scholarly journals Diagnosing Sporadic Creutzfeldt-Jakob Disease in a Patient with a Suspected Status Epilepticus in the Intensive Care Unit

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Harm J. van der Horn ◽  
Peter H. Egbers ◽  
Michaël A. Kuiper ◽  
Wouter J. Schuiling
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Status Epilepticus ◽  
Tau Protein ◽  
Psychiatric Symptoms ◽  
Clinical Signs ◽  
Review Of The Literature ◽  
Protein Determination ◽  
Jakob Disease ◽  
Antiepileptic Drug Therapy

Objective. Several tests are available in the diagnostics of sporadic Creutzfeldt-Jakob disease (sCJD); however, none of these is conclusive. We review the values of these tests, from an intensive care unit (ICU) perspective.Methods. Case report and review of the literature.Results. A 53-year-old woman initially presenting with psychiatric symptoms developed myoclonus and was admitted 1 month later to the ICU with a suspected nonconvulsive status epilepticus and respiratory insufficiency, probably due to extensive antiepileptic drug therapy. Typical MRI and EEG findings and a positive 14-3-3 protein led to the diagnosis of sCJD. All treatments were terminated, and autopsy confirmed sCJD.Conclusions. Clinical signs combined with MRI, EEG, and 14-3-3 and/or tau protein determination might be sufficient to diagnose or exclude sCJD and may therefore prevent the application of unnecessary diagnostic tests.

Electroconvulsive therapy in the intensive care unit for the treatment of catatonia: a case series and review of the literature

2016 ◽  
Vol 38 ◽  
pp. 37-41 ◽  
Author(s):  
Femke M. Dessens ◽  
Judith van Paassen ◽  
David J. van Westerloo ◽  
Nic J. van der Wee ◽  
Irene M. van Vliet ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Electroconvulsive Therapy ◽  
Case Series ◽  
Review Of The Literature

Rapidly Progressive Dementia and Coma

2019 ◽  
pp. 704-712
Author(s):  
Prasuna Kamireddi ◽  
Jason L. Siegel ◽  
Dennis W. Dickson
Keyword(s):  
Intensive Care Unit ◽  
Functional Ability ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Cognitive Domain ◽  
Progressive Dementia ◽  
Common Causes ◽  
Jakob Disease ◽  
Clinical Signs And Symptoms ◽  
Definition Of

In most patients with dementia, the clinical signs and symptoms progress gradually over many years. However, neurointensivists may encounter patients who have rapidly progressive dementia (RPD). Often these patients need to be admitted to the intensive care unit for management of status epilepticus, agitation, or ventilation in coma. Although the prototype of RPD is Creutzfeldt-Jakob disease, this chapter reviews other common causes of RPD. An established definition of RPD does not exist, but in this chapter RPD refers to the loss of more than 1 cognitive domain and functional ability, usually occurring over a few months.

Status epilepticus related to pregnancy: Devising a protocol for use in the intensive care unit

2018 ◽  
Vol 66 (6) ◽  
pp. 1629 ◽  
Author(s):  
Ashalatha Radhakrishnan ◽  
KeniRavish Rajiv ◽  
RamshekharN Menon ◽  
Sajith Sukumaran ◽  
Ajith Cherian ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Status Epilepticus

Time to Detection of the First Seizure in Patients With Nonconvulsive Status Epilepticus in the Neurological Intensive Care Unit

2019 ◽  
Vol 51 (1) ◽  
pp. 70-73
Author(s):  
Nese Dericioglu ◽  
Ethem Murat Arsava ◽  
Mehmet Akif Topcuoglu
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Status Epilepticus ◽  
Eeg Monitoring ◽  
Neurological Intensive Care Unit ◽  
Neurological Intensive Care ◽  
Eeg Recordings ◽  
Gcs Score ◽  
Early Seizure ◽  
Video Eeg

Video-EEG monitoring is often used to detect nonconvulsive status epilepticus (NCSE) in critical care patients. Short recording durations may fail to detect seizures. In this study, we investigated the time required to record the first ictal event, and whether it could be correlated with some clinical or EEG parameters. Video-EEG recordings of patients who were followed up in our neurological intensive care unit were evaluated retrospectively. The EEG recordings of patients with NCSE were reviewed to determine the timing of the first seizure occurrence. Demographic data and EEG findings were obtained from patient charts and EEG reports. Possible correlations between the presence of periodic discharges (PD), Glasgow Coma Scale (GCS) score and early seizure detection (defined as a seizure within the first hour of recording) were explored statistically. Out of 200 patients who underwent video-EEG monitoring, we identified 30 cases (15%; 18 male, 12 female; age 24-86 years; mean recording duration 99 hours) with NCSE. The first seizure was recorded within 0 to 1 hour in 22 patients (73%) and within 1 to 12 hours in 6 patients (22%). Interictal PDs were identified in 19 patients (63%). GCS score was ≤8 in 16 patients (53%). There was no correlation between early seizure detection and PDs (p=1.0) or GCS score ( P = .22). In our study, >90% of the seizures were captured within 12 hours. This finding suggests that most of the NCSE cases can be identified even in centers with limited resources. The presence or absence of PDs or GCS score does not predict the timing of the first seizure.

Status epilepticus; Experience in our intensive care unit since 2014

2019 ◽  
Vol 101 ◽  
pp. 106747
Author(s):  
Luisa M. Charco-Roca ◽  
Alberto Grande-Martín ◽  
Jose M. Jimenez-Vizuete ◽  
Ramón Peyró-Garcia ◽  
Pedro M. Canales-Lara ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Status Epilepticus
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