scholarly journals Development of Microencapsulation Delivery System for Long-Term Preservation of Probiotics as Biotherapeutics Agent

2013 ◽  
Vol 2013 ◽  
pp. 1-21 ◽  
Author(s):  
Himanshu K. Solanki ◽  
Dipak D. Pawar ◽  
Dushyant A. Shah ◽  
Vipul D. Prajapati ◽  
Girish K. Jani ◽  
...  
Keyword(s):  
Methodological Approach ◽  
Health Benefit ◽  
Global Market ◽  
Appropriate Technology ◽  
Physical Barrier ◽  
Bile Concentration ◽  
Adverse Environmental Conditions ◽  
Long Term Preservation ◽  
Harsh Conditions

The administration of probiotic bacteria for health benefit has rapidly expanded in recent years, with a global market worth $32.6 billion predicted by 2014. The oral administration of most of the probiotics results in the lack of ability to survive in a high proportion of the harsh conditions of acidity and bile concentration commonly encountered in the gastrointestinal tract of humans. Providing probiotic living cells with a physical barrier against adverse environmental conditions is therefore an approach currently receiving considerable interest. Probiotic encapsulation technology has the potential to protect microorganisms and to deliver them into the gut. However, there are still many challenges to overcome with respect to the microencapsulation process and the conditions prevailing in the gut. This review focuses mainly on the methodological approach of probiotic encapsulation including biomaterials selection and choice of appropriate technology in detailed manner.

A Preparation based on Bacteria Isolated from Hypersaline Environments to Improve the Functional and Protective Characteristics of Concrete

2020 ◽  
Vol 36 (4) ◽  
pp. 21-28
Author(s):  
N.B. Gradova ◽  
S.P. Sivkov ◽  
E.V. Agalakova ◽  
A.A. Belov ◽  
N.A. Suyasov ◽  
...  
Keyword(s):  
Environmental Conditions ◽  
Hypersaline Environment ◽  
Cement Stone ◽  
Self Healing ◽  
Crack Healing ◽  
Cement Mixture ◽  
Adverse Environmental Conditions ◽  
Long Term Preservation ◽  
Bacterial Preparations

Improving the strength and stability of cement-based structures in adverse environmental conditions with associated anthropogenic influences is possible through the development and implementation of nature-like and nature-friendly technologies. The ability of urobacteria to precipitate calcium carbonate can be useful in the manufacture of self-healing and reinforced concrete, in the crack healing and the restoration of concrete structures. Hypersaline environment is an ecological niche for search for microorganisms that are resistant to increased alkalinity, changing environmental conditions and stress. Screening of microorganisms allowed us to isolate the most active urobacteria, Lysinibacillus macroides and Bacillus licheniformis, from hypersaline lakes. The introduction of these microorganisms into the cement mixture significantly increased the strength of mortar specimens, reduced their porosity and capillary water absorption, which was associated with ongoing biocalcination. We studied the microstructure of spores of diatomite-immobilized bacteria and showed that this form provided long-term preservation of bacterial activity. A high activity of bacterial preparations in the healing of cement stone cracks was found. biomineralization, biocementation, extreme halophiles, crack healing, cement mortar, microbial concrete, urea hydrolysis. The work was supported by the D. Mendeleev University of Chemical Technology of Russia (Project no. 033-2018).

Problems of treatment of primary openangle glaucoma in combination with thrombosis of the central retinal vein

GlaucomaNews ◽  
2020 ◽  
pp. 65-69
Author(s):  
T.E. Lipatkina ◽  
◽  
Е.V. Karlova ◽  
A.V. Zolotarev ◽  
◽  
...  
Keyword(s):  
Macular Edema ◽  
Primary Open Angle Glaucoma ◽  
Antihypertensive Drugs ◽  
Open Angle Glaucoma ◽  
Vascular Wall ◽  
Open Angle ◽  
Retinal Edema ◽  
Long Term Preservation ◽  
Central Retinal Vein

Patients with primary open-angle glaucoma (POAG) and ophthalmic hypertension have an increased likelihood of developing occlusions (thrombosis) of the central retinal vein. Different groups of antihypertensive drugs differ in their mechanism of action and may affect concomitant ocular pathology, in particular, retinal edema, which occurs, for example, in occlusion of the central retinal vein. Used in most patients with glaucoma, prostaglandin analogs can contribute to the long-term preservation of macular edema due to the effect on the permeability of the vascular wall. Preparations of other pharmacological groups, reducing the production of aqueous humor, on the contrary, may contribute to its regression. Therefore, the question of choosing a drug for antihypertensive therapy in patients with primary open-angle glaucoma and concomitant macular edema is relevant and is for further study.

Threatening Conditions and Challenges in the Modern Living of the Old People in Republic of Macedonia

2016 ◽  
Vol 2 (2) ◽  
pp. 110
Author(s):  
Hava Rexhep
Keyword(s):  
Kidney Diseases ◽  
Methodological Approach ◽  
Research Problem ◽  
Functional Dependency ◽  
Old People ◽  
Stomach Diseases ◽  
Social Challenge ◽  
The Social ◽  
Build System

The aging is not only a personal but also a social challenge from several aspects, several dimensions; a challenge aiming to build system approaches and solutions with a long term importance. Aims: the main aim of this research is to investigate the conditions and challenges in the modern living of the old people, primarily in terms of the social care. However, this research is concentrated on a big group of the population and their challenges are the most intensive in the modern living. The investigation of the conditions and challenges in the aging are basis and encouragement in realizing the progressive approaches in order to improve the modern living of the old people. The practical aim of the research is a deep investigation and finding important data, analyzing the basic indicators of the conditions, needs and challenges in order to facilitate the old population to get ready for the new life. Methods and techniques: Taking into consideration the complexity of the research problem, the basic methodological approach is performed dominantly by descriptive-analytical method. The basic instrument for getting data in the research is the questionnaire with leading interview for the old people. Results: The research showed that the old people over 70-79 years old in a bigger percentage manifested difficulties primarily related to the functional dependency, respectively 39,33 % of the participants in this category showed concern about some specific functional dependency from the offered categories. The percentage of the stomach diseases with 38,33 % is important, as well as the kidney diseases with 32,83% related to the total population and the category of the old people over 80. Conclusion: The old people very often accept the life as it is, often finding things fulfilled with tolerance and satisfaction. However the health problems of the old people are characterized with a dominant representation. The chronic diseases and the diseases characteristic for the aging are challenge in organizing adequate protection which addresses to taking appropriate regulations, programs and activities.

Trends and Prospects of Development of the Oil and Gas Sector in the Context of Digitalization

2020 ◽  
Vol 26 (1) ◽  
pp. 35-45 ◽  
Author(s):  
A. G. Kazanin
Keyword(s):  
Oil And Gas ◽  
Digital Technologies ◽  
Oil And Gas Industry ◽  
Global Market ◽  
The Arctic ◽  
Business And Society ◽  
Gas Industry ◽  
Exploration And Production ◽  
Oil And Gas Sector

The modern oil and gas industry is heavily dependent on the processes and trends driven by the accelerating digitalization of the economy. Thus, the digitalization of the oil and gas sector has become Russia’s top priority, which involves a technological and structural transformation of all production processes and stages.Aim. The presented study aims to identify the major trends and prospects of development of the Russian oil and gas sector in the context of its digitalization and formation of the digital economy.Tasks. The authors analyze the major trends in the development of the oil and gas industry at a global scale and in Russia with allowance for the prospects of accelerated exploration of the Arctic; determine the best practices of implementation of digital technologies by oil and gas companies as well as the prospects and obstacles for the subsequent transfer of digital technologies to the Russian oil and gas industry.Methods. This study uses general scientific methods, such as analysis, synthesis, and scientific generalization.Results. Arctic hydrocarbons will become increasingly important to Russia in the long term, and their exploration and production will require the implementation of innovative technologies. Priority directions for the development of many oil and gas producers will include active application of digital technologies as a whole (different types of robots that could replace people in performing complex procedures), processing and analysis of big data using artificial intelligence to optimize processes, particularly in the field of exploration and production, processing and transportation. Digitalization of the oil and gas sector is a powerful factor in the improvement of the efficiency of the Russian economy. However, Russian companies are notably lagging behind in this field of innovative development and there are problems and high risks that need to be overcome to realize its potential for business and society.Conclusions. Given the strategic importance of the oil and gas industry for Russia, its sustainable development and national security, it is recommendable to focus on the development and implementation of digital technologies. This is crucial for the digitalization of long-term projection and strategic planning, assessment of the role and place of Russia and its largest energy companies in the global market with allowance for a maximum number of different internal and external factors.

Comparison of Polarized and Depolarized Arrest in the Isolated Rat Heart for Long-term Preservation

Circulation ◽  
1997 ◽  
Vol 96 (9) ◽  
pp. 3148-3156 ◽  
Author(s):  
A. K. Snabaitis ◽  
M. J. Shattock ◽  
D. J. Chambers
Keyword(s):  
Rat Heart ◽  
Isolated Rat Heart ◽  
Long Term Preservation ◽  
Isolated Rat

Online Publication of Monuments

2020 ◽  
pp. 355-369
Author(s):  
Willeke Wendrich
Keyword(s):  
Peer Review ◽  
3D Modeling ◽  
Online Publication ◽  
New Technologies ◽  
3D Scanning ◽  
Architectural Drawings ◽  
3D Gis ◽  
Unity 3D ◽  
Long Term Preservation

This chapter outlines the advantages of digital epigraphy in the context of the original monuments. It analyzes the perception of epigraphic publication of monuments, taking into account new technologies. 3DVR models can be created using architectural drawings and measurements (CAD and 3D modeling), 3D scanning, and Structure for Motion (SfM). These systems present different advantages and challenges, which are discussed. Current options for publication include VSim, 3D GIS, and Unity 3D platforms. The issues of peer review of publications and long-term preservation of data are addressed. The chapter concludes with a consideration of the issue of potentially misleading impressions given by 3DVR representations.

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