scholarly journals Mucoepidermoid Carcinoma in a Minor Salivary Gland in a Child

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Fatih Sengul ◽  
Sera Simsek ◽  
Binali Cakur
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Minor Salivary Gland ◽  
Differential Diagnoses ◽  
Common Site ◽  
Radiological Findings ◽  
Pathologic Lesions ◽  
A Minor

Mucoepidermoid carcinoma (MEC), one of the most common salivary gland malignancies, is rare in children. MEC mainly occurs in the parotid gland, along with minor glands being the second common site, particularly in palate. Clinical, histological, and radiological findings of palatal MEC in a 12-year-old girl are presented with three-year follow-up. Pathologic lesions must be considered in differential diagnoses of intraoral asymptomatic lesions, and their detailed inspection should be taken into consideration.

scholarly journals Warthin tumor of the oropharyngeal minor salivary gland

2018 ◽  
Vol 6 ◽  
pp. 2050313X1881871 ◽  
Author(s):  
Nicole Diaz-Segarra ◽  
Lauren K Young ◽  
Kristin Levin ◽  
William Rafferty ◽  
Joshua Brody ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Minor Salivary Gland ◽  
Previous History ◽  
Salivary Gland Tumor ◽  
Gland Tumor ◽  
Warthin Tumor ◽  
Diagnosis And Management ◽  
History Of ◽  
A Minor

Warthin tumor is the second most common benign salivary gland tumor that classically arises in the parotid gland. It can be synchronous, metachronous, multifocal, bilateral, or unilateral, which complicates diagnosis and management. Rare cases of Warthin tumor of the minor salivary gland are described, but no cases of unilateral, synchronous Warthin tumor involving the parotid and minor salivary gland have been reported. We present a case of Warthin tumor arising from a minor salivary gland in the left oropharynx of a 71-year-old male with a previous history of left parotid Warthin tumor, later determined to be synchronous.

Low Grade Mucoepidermoid Carcinoma of a Minor Salivary Gland of the Tongue in a Paediatric Patient

2018 ◽  
Vol 69 (6) ◽  
pp. 367-369
Author(s):  
María Fernanda Vargas Gamarra ◽  
José María Perolada Vilmaña ◽  
Miguel Armengot Carceller
Keyword(s):  
Salivary Gland ◽  
Paediatric Patient ◽  
Mucoepidermoid Carcinoma ◽  
Minor Salivary Gland ◽  
Low Grade ◽  
A Minor

Mucoepidermoid carcinoma in a minor salivary gland in childhood

1987 ◽  
Vol 101 (12) ◽  
pp. 1320-1323 ◽  
Author(s):  
Hans Gustafsson ◽  
Åke Dahlqvist ◽  
Matti Anniko ◽  
Bengt Carlsöö
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Adult Population ◽  
Minor Salivary Gland ◽  
Childhood And Adolescence ◽  
Minor Salivary Glands ◽  
Salivary Gland Tumours ◽  
Pediatric Age Group ◽  
Pleomorphic Adenomas ◽  
A Minor

SummarySalivary gland neoplasms in childhood and adolescence are rare, especially in the minor salivary glands. Vasoformative tumours and pleomorphic adenomas appear to be the most common benign neoplastic salivary gland lesions in the pediatric age group. The distribution of various malignant histological types is not always consistent with that in the adult population, and they appear more often in girls than in boys. Only 17 cases have previously been documented. The clinical and histological picture of a case of palatal mucoepidermoid carcinoma in a 13-year-old girl is presented as well as a review of the literature on malignant salivary gland tumours in childhood.

P1.16. A rare case of mucoepidermoid carcinoma ex pleomorphic adenoma of a minor salivary gland

2009 ◽  
Vol 3 (1) ◽  
pp. 128
Author(s):  
L.J. Grando ◽  
F. Modolo ◽  
E.R.C. Rivero ◽  
S.C.O.M. de Souza ◽  
M.I. Meurer ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Rare Case ◽  
Minor Salivary Gland ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
A Minor

A Case of Mucoepidermoid Carcinoma Arising from the Intraoral Minor Salivary Gland

2017 ◽  
Vol 33 (1) ◽  
pp. 39-41
Author(s):  
Hun Hee Baek ◽  
◽  
Seok Jung Hong ◽  
Mi Ji Lee ◽  
Seung Woo Kim ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Mucoepidermoid Carcinoma ◽  
Minor Salivary Gland

scholarly journals POS0782 FOLLICULAR DENDRITIC CELL NETWORKS IN MINOR SALIVARY GLAND BIOPSIES: A MARKER OF DISEASE ACTIVITY AT BASELINE AND DURING THE FOLLOW-UP IN SJÖGREN’S SYNDROME

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 644.2-644
Author(s):  
C. Baldini ◽  
F. Ferro ◽  
G. Fulvio ◽  
G. La Rocca ◽  
S. Fonzetti ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Dendritic Cell ◽  
Disease Activity ◽  
Inflammatory Infiltrate ◽  
Minor Salivary Gland ◽  
Sjogren’S Syndrome ◽  
Follicular Dendritic Cell ◽  
Sjogren's Syndrome ◽  
Follicular Dendritic

Background:Minor salivary gland biopsy (MSGB) has been increasingly recognized as an important tool for the stratification of patients with primary Sjögren’s syndrome (pSS). Recently, the presence of follicular dendritic cell (FDC) networks in the inflammatory infiltrate has been associated with more severe biological and serological abnormalities compared with less organized infiltrates.Objectives:To investigate the associations between the presence and number of FDC networks in foci and pSS glandular and extra-glandular disease activity at baseline and during the follow-up.Methods:Consecutive MSGBs performed in daily practice for clinically suspected pSS from January 2017 to October 2020 were reviewed. Patients’ demographic, clinical, biological and serological data were obtained from medical records. The ESSDAI was used to measure disease activity at baseline and at the end of the follow-up in pSS patients. For histopathology, 3 µm sections were cut from each formalin-fixed paraffin-embedded block of MSGBs and stained with haematoxylin and eosin (H&E). Immunohistochemical stainings were performed on additional 3 μm sections in order to detect T lymphocytes (CD3), B lymphocytes (CD20) and follicular dendritic cells (CD21). Glandular tissue areas, number of foci, focus score (FS) and the presence and number of FDC networks were assessed.Results:We reviewed 330 consecutive MSGBs from patients with suspected pSS: out of them 146/330 (44%) were classified as nonspecific chronic sialadenitis (NSCS) whereas 184/330 (56%) as focal lymphocytic sialadenitis (FLS). According to the ACR/EULAR criteria the diagnosis of pSS was confirmed in 130 patients (117 F:13 M, age 56±13 yrs). The mean (S.D) surface area of the MSGBs was 7.8 (3.9) mm2. The number of foci in the FLS samples ranged from 1 to 12 (mean (S.D)=3.1 (2.6)), whereas the FS ranged from 0.3 to 9.0 (mean (S.D) = 1.4 (1.2)).The presence of FDC networks was documented in 106/330 (32%) of the samples; in 54/106 (51%) of these MSGBs the number of FDC networks ranged from 2 to 8 (mean (S.D)=3.1 (1.4)). The number of FDC networks significantly correlated with the number of foci (r=0.721**) and FS (r=0.707**). Patients with FDC networks in the inflammatory infiltrate presented more serological abnormalities (i.e anti-Ro/SSA, anti-LA/SSB, Rheumatoid factor) and elevated IgG levels (p<0.001). In pSS patients, the number of FDC networks slightly correlated also with C4 levels (r=-0.216*), peripheral lymphocyte count (r=-0.274**) and with glandular (r=0.213*), and biological (r=0.230**) domains of the ESSDAI at baseline. After a mean (S.D) follow-up of 21(13) months, the number of FDC networks still correlated with the final total ESSDAI (r=0.312**).Conclusion:The presence and number of FDC networks in foci represent a useful histopathological parameter able to reflect disease activity at baseline and during the follow-up, thus allowing more personalized interventions.Disclosure of Interests:None declared

Sialolithiasis with sialoadenitis of a minor salivary gland

1970 ◽  
Vol 30 (3) ◽  
pp. 320-324 ◽  
Author(s):  
Gerald DeGregori ◽  
Robert Pippen
Keyword(s):  
Salivary Gland ◽  
Minor Salivary Gland ◽  
A Minor

Hyalinizing clear cell carcinoma of the nasopharynx operated by trans-oral and trans-palatal approach

2015 ◽  
Vol 129 (S2) ◽  
pp. S95-S97 ◽  
Author(s):  
T Nakashima ◽  
R Yasumatsu ◽  
M Yamauchi ◽  
S Toh ◽  
T Nakano ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Cell Carcinoma ◽  
Surgical Resection ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Minor Salivary Gland ◽  
Good Prognosis ◽  
Salivary Gland Neoplasm ◽  
Hyalinizing Clear Cell Carcinoma

AbstractBackground:Hyalinizing clear cell carcinoma is a rare minor salivary gland neoplasm. The treatment of choice is surgical resection with or without post-operative radiotherapy. This tumour often demonstrates a good prognosis.Case report:We report a case of hyalinizing clear cell carcinoma arising in the nasopharynx. A 27-year-old female presented with progressive hearing disturbance and tinnitus. On examination, an expansile mass was observed in her nasopharynx. Biopsy was performed and the pathology results returned as clear cell carcinoma.Results and conclusion:Surgical resection was performed trans-orally accompanied by trans-palatal approach. She has no recurrence during more than two years of follow up.

Minor salivary gland biopsy: its importance in rheumatoid arthritis and secondary Sjögren's síndrome

2019 ◽  
pp. 15-18
Author(s):  
María Florencia Rodriguez ◽  
Cristian Troitiño ◽  
Felix Enrique Romanini ◽  
Anastasia Secco
Keyword(s):  
Rheumatoid Arthritis ◽  
Multivariate Analysis ◽  
Salivary Gland ◽  
Interstitial Lung Disease ◽  
Univariate Analysis ◽  
Minor Salivary Gland ◽  
Minor Salivary Gland Biopsy ◽  
Extraglandular Manifestations ◽  
Salivary Gland Biopsy

Secondary Sjögren’s Syndrome (SSs) is common in patients with Rheumatoid Arthritis (RA). Objectives: to determine if lymphocytic sialoadenifitis (FLS) is associated with clinical and serological differences in a group of patients with RA and SSs. Methods: patients with a diagnosis of RA and SSs were included, which of them presented FLS in the salivary gland biopsy, clinical and serological characteristics were compared. Results: 88 patients were included, 92% women, mean age of 53 years (SD ± 11.3) and 12.5 years of evolution of RA (RIC 6-7). 63.6% had SLF versus 36.4% who did not. In the univariate analysis, a statistically significant association was found between FLS + and the variables: parotidomegaly, interstitial lung disease, hypergammaglobulinemia, hypocomplementemia, rheumatoid factor, positive ANF, and extra-articular and/ or extraglandular manifestations. In the multivariate analysis, the variables independently associated with the presence of FLS were: extra-articular and/or extraglandular manifestations (OR 5.67, 95% CI 1.6-20), positive ANF (OR 11.7, 95% CI 1.6-83) and hypergammaglobulinemia (OR 21, 95% CI 2.46-179). Conclusion: patients with RA and SSs with FLS have a higher frequency of extra-articular and extraglandular manifestations and serological differences, which would imply a different clinical follow-up.

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