scholarly journals Oat Protects against Diabetic Nephropathy in Rats via Attenuating Advanced Glycation End Products and Nuclear Factor Kappa B

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Abdulrahman L. Al-Malki
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
Advanced Glycation ◽  
Nuclear Factor Kappa ◽  
Glycation End Products ◽  
End Products

scholarly journals Tropisetron modulates peripheral and central serotonin/insulin levels via insulin and nuclear factor kappa B/receptor for advanced glycation end products signalling to regulate type-2 diabetes in rats

RSC Advances ◽  
2018 ◽  
Vol 8 (22) ◽  
pp. 11908-11920
Author(s):  
Reem Ali Mohamed ◽  
Omneya Galal ◽  
Ahmed Refaat Mohammed ◽  
Hanan Salah El-Abhar
Keyword(s):  
Type 2 Diabetes ◽  
Signaling Pathways ◽  
Advanced Glycation End Products ◽  
Nuclear Factor Kappa B ◽  
Nuclear Factor ◽  
Advanced Glycation ◽  
Insulin Levels ◽  
Glycation End Products ◽  
End Products

Schematic illustration of tropisetron's (5-HT3 antagonist) modulation of the insulin and Wnt/β-catenin signaling pathways both peripherally and centrally in type 2 diabetes.

Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-Ay/Ta mice

Metabolism ◽  
2007 ◽  
Vol 56 (2) ◽  
pp. 160-167 ◽  
Author(s):  
Mitsuo Tanimoto ◽  
Tomohito Gohda ◽  
Shigeru Kaneko ◽  
Shinji Hagiwara ◽  
Maki Murakoshi ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Type 2 Diabetic

scholarly journals Advanced glycation end-products in diabetic nephropathy

1996 ◽  
Vol 11 (supp5) ◽  
pp. 91-94 ◽  
Author(s):  
S. Sugiyama ◽  
T. Miyata ◽  
K. Horie ◽  
Y. Iida ◽  
M. Tsuyuki ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Advanced Glycation End Products ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

AGE, RAGE and Diabetic Nephropathy

2010 ◽  
Vol 8 (2) ◽  
pp. 84
Author(s):  
MaÏté Daroux ◽  
Nicolas Grossin ◽  
Eric Boulanger ◽  
◽  
◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Diabetic Nephropathy ◽  
Kidney Disease ◽  
Advanced Glycation End Products ◽  
Specific Treatment ◽  
Therapeutic Approaches ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Immunohistochemical Studies

Diabetes is a disease that is present worldwide and which is associated with a large number of potential complications including chronic kidney disease (CKD). Several factors have been implicated in the development of the latter, including advanced glycation end-products (AGEs), which are formed from the interaction between sugar and proteins. AGE toxicity may be triggered via different mechanisms, especially by receptor binding. Immunohistochemical studies have demonstrated the presence of AGEs in all renal structures (vessels, glomeruli, tubules and the interstitium). They appear to be involved in the exacerbation of renal injury observed during diabetic nephropathy. At present, no specific treatment is yet available, although several therapeutic approaches are under development.

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