scholarly journals Neurostimulation for Neurogenic Bowel Dysfunction

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
J. Worsøe ◽  
M. Rasmussen ◽  
P. Christensen ◽  
K. Krogh
Keyword(s):  
Nerve Stimulation ◽  
Magnetic Stimulation ◽  
Bowel Function ◽  
Bowel Dysfunction ◽  
Cochrane Library ◽  
Congenital Defects ◽  
Clinical Use ◽  
Pilot Studies ◽  
Cord Injury ◽  
Neurogenic Bowel

Background. Loss of normal bowel function caused by nerve injury, neurological disease or congenital defects of the nervous system is termed neurogenic bowel dysfunction (NBD). It usually includes combinations of fecal incontinence, constipation, abdominal pain and bloating. When standard treatment of NBD fails surgical procedures are often needed. Neurostimulation has also been investigated, but no consensus exists about efficacy or clinical use.Methods. A systematic literature search of NBD treated by sacral anterior root stimulation (SARS), sacral nerve stimulation (SNS), peripheral nerve stimulation, magnetic stimulation, and nerve re-routing was made in Pubmed, Embase, Scopus, and the Cochrane Library.Results. SARS improves bowel function in some patients with complete spinal cord injury (SCI). Nerve re-routing is claimed to facilitate defecation through mechanical stimulation of dermatomes in patients with complete or incomplete SCI or myelomeningocele. SNS can reduce NBD in selected patients with a variety of incomplete neurological lesions. Peripheral stimulation using electrical stimulation or magnetic stimulation may represent non-invasive alternatives.Conclusion. Numerous methods of neurostimulation to treat NBD have been investigated in pilot studies or retrospective studies. Therefore, larger controlled trials with well-defined inclusion criteria and endpoints are recommended before widespread clinical use of neurostimulation against NBD.

scholarly journals Efficacy of functional magnetic stimulation in neurogenic bowel dysfunction after spinal cord injury

2009 ◽  
Vol 41 (1) ◽  
pp. 41-47 ◽  
Author(s):  
PY Tsai ◽  
CP Wang ◽  
FY Chiu ◽  
YA Tsai ◽  
YC Chang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Magnetic Stimulation ◽  
Bowel Dysfunction ◽  
Cord Injury ◽  
Neurogenic Bowel

scholarly journals Faecal Microbiota in Patients with Neurogenic Bowel Dysfunction and Spinal Cord Injury or Multiple Sclerosis—A Systematic Review

2021 ◽  
Vol 10 (8) ◽  
pp. 1598
Author(s):  
Willemijn Faber ◽  
Janneke Stolwijk-Swuste ◽  
Florian van Ginkel ◽  
Janneke Nachtegaal ◽  
Erwin Zoetendal ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Methodological Quality ◽  
Alpha Diversity ◽  
Bowel Function ◽  
Antibiotic Use ◽  
Bowel Dysfunction ◽  
Healthy Controls ◽  
Cord Injury ◽  
Neurogenic Bowel

Background: Neurogenic bowel dysfunction (NBD) frequently occurs in patients with spinal cord injury (SCI) and multiple sclerosis (MS) with comparable symptoms and is often difficult to treat. It has been suggested the gut microbiota might influence the course of NBD. We systematically reviewed the literature on the composition of the gut microbiota in SCI and MS, and the possible role of neurogenic bowel function, diet and antibiotic use. Methods: A systematic search was conducted in PubMed and Embase, which retrieved studies on the gut microbiota in SCI and MS. The Newcastle–Ottawa Quality Assessment Scale (NOS) was used to assess methodological quality. Results: We retrieved fourteen papers (four on SCI, ten on MS), describing the results of a total of 479 patients. The number of patients per study varied from 13 to 89 with an average of 34. Thirteen papers were observational studies and one study was an intervention study. The studies were case control studies in which the gut microbiota composition was determined by 16S rRNA gene sequencing. The methodological quality of the studies was mostly rated to be moderate. Results of two studies suggested that alpha diversity in chronic SCI patients is lower compared to healthy controls (HC), whereas results from five studies suggest that the alpha diversity of MS patients is similar compared to healthy subjects. The taxonomic changes in MS and SCI studies are diverse. Most studies did not account for possible confounding by diet, antibiotic use and bowel function. Conclusion: Based on these 14 papers, we cannot draw strong conclusions on the composition of the gut microbiota in SCI and MS patients. Putatively, alpha diversity in chronic SCI patients may be lower compared to healthy controls, while in MS patients, alpha diversity may be similar or lower compared to healthy controls. Future studies should provide a more detailed description of clinical characteristics of participants and of diet, antibiotic use and bowel function in order to make valid inferences on changes in gut microbiota and the possible role of diet, antibiotic use and bowel function in those changes.

scholarly journals Neurogenic bowel dysfunction

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1800 ◽  
Author(s):  
Anton Emmanuel
Keyword(s):  
Quality Of Life ◽  
Neurological Diseases ◽  
Bowel Function ◽  
Bowel Dysfunction ◽  
Laxative Use ◽  
Cord Injury ◽  
Surgical Options ◽  
Neurogenic Bowel ◽  
Monitoring Response

The symptoms of neurogenic bowel dysfunction (NBD) comprise constipation and fecal incontinence. These have a major impact on quality of life and dignity. Bowel symptoms occur in the majority of patients with chronic neurological diseases like multiple sclerosis, spinal cord injury, and Parkinson’s disease. Management relies on obtaining a careful bowel history, including assessment of bowel function prior to the onset of neurological symptoms. Objective measures of NBD are available and important in terms of monitoring response for what are often intensely personal and difficult-to-elicit symptoms. Conservative management begins by establishing an effective and regular bowel regime by optimizing diet and laxative use. If this is insufficient, as seen in about half of patients, transanal irrigation has been shown to reduce NBD symptoms and improve quality of life. Failing that, there are more invasive surgical options available. This review aims to provide practical guidance for the clinician who encounters these patients, focusing on a stepwise approach to assessment, interventions, and monitoring.

scholarly journals The Effect of Exoskeletal-Assisted Walking on Spinal Cord Injury Bowel Function: Results from a Randomized Trial and Comparison to Other Physical Interventions

2021 ◽  
Vol 10 (5) ◽  
pp. 964
Author(s):  
Peter H. Gorman ◽  
Gail F. Forrest ◽  
Pierre K. Asselin ◽  
William Scott ◽  
Stephen Kornfeld ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bowel Function ◽  
Bowel Dysfunction ◽  
Secondary Outcome ◽  
Secondary Outcome Measure ◽  
Cord Injury ◽  
Patient Reported ◽  
Stool Form ◽  
Time Since Injury

Bowel function after spinal cord injury (SCI) is compromised because of a lack of voluntary control and reduction in bowel motility, often leading to incontinence and constipation not easily managed. Physical activity and upright posture may play a role in dealing with these issues. We performed a three-center, randomized, controlled, crossover clinical trial of exoskeletal-assisted walking (EAW) compared to usual activity (UA) in people with chronic SCI. As a secondary outcome measure, the effect of this intervention on bowel function was assessed using a 10-question bowel function survey, the Bristol Stool Form Scale (BSS) and the Spinal Cord Injury Quality of Life (SCI-QOL) Bowel Management Difficulties instrument. Fifty participants completed the study, with bowel data available for 49. The amount of time needed for the bowel program on average was reduced in 24% of the participants after EAW. A trend toward normalization of stool form was noted. There were no significant effects on patient-reported outcomes for bowel function for the SCI-QOL components, although the time since injury may have played a role. Subset analysis suggested that EAW produces a greater positive effect in men than women and may be more effective in motor-complete individuals with respect to stool consistency. EAW, along with other physical interventions previously investigated, may be able to play a previously underappreciated role in assisting with SCI-related bowel dysfunction.

scholarly journals Reliability, validity and sensitivity to change of neurogenic bowel dysfunction score in patients with spinal cord injury

Spinal Cord ◽  
2017 ◽  
Vol 55 (12) ◽  
pp. 1084-1087 ◽  
Author(s):  
D Erdem ◽  
D Hava ◽  
P Keskinoğlu ◽  
Ç Bircan ◽  
Ö Peker ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bowel Dysfunction ◽  
Sensitivity To Change ◽  
Cord Injury ◽  
Neurogenic Bowel

scholarly journals Prediction of severe neurogenic bowel dysfunction in persons with spinal cord injury

Spinal Cord ◽  
2010 ◽  
Vol 48 (7) ◽  
pp. 554-559 ◽  
Author(s):  
C-W Liu ◽  
C-C Huang ◽  
C-H Chen ◽  
Y-H Yang ◽  
T-W Chen ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bowel Dysfunction ◽  
Cord Injury ◽  
Neurogenic Bowel
Sign in / Sign up

Export Citation Format

Share Document