scholarly journals A Novel Study of Comorbidity between Schizoaffective Disorder and Geschwind Syndrome

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Kara O'Connell ◽  
Joanne Keaveney ◽  
Raymond Paul
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Schizoaffective Disorder ◽  
Brain Mri ◽  
Clinical Findings ◽  
Correct Identification ◽  
Behavioural Disorders ◽  
Structural Abnormalities ◽  
The Right ◽  
Lobe Atrophy

Geschwind syndrome has been described in patients with temporal lobe epilepsy and is characterized by sexual behavioural disorders, hyperreligiosity, hypergraphia, and viscosity. Presented here is a case of a 53-year-old man with clinical findings consistent with Geschwind syndrome in the setting of a known diagnosis of schizoaffective disorder, with no identifiable comorbid illness of temporal lobe epilepsy or frontotemporal dementia. Brain MRI showed bilateral temporal lobe atrophy greater than would be expected for age and more prominent on the left side than the right. It is likely that these structural abnormalities may be related to this patient’s clinical presentation of Geschwind syndrome. To our knowledge, this is the first reporting of a case of Geschwind syndrome in the setting of schizoaffective disorder. These symptoms of Geschwind syndrome were present irrespective of mental state status. The report highlights the importance in correct identification of underlying cause and differentiation between Geschwind syndrome and schizoaffective disorder in order to avoid mistreatment and consequent iatrogenic adverse events.

scholarly journals Extrahippocampal temporal lobe atrophy in temporal lobe epilepsy and mesial temporal sclerosis

Brain ◽  
2001 ◽  
Vol 124 (1) ◽  
pp. 167-175 ◽  
Author(s):  
N. F. Moran ◽  
L. Lemieux ◽  
N. D. Kitchen ◽  
D. R. Fish ◽  
S. D. Shorvon
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Mesial Temporal Sclerosis ◽  
Lobe Atrophy

Transsylvian hippocampal transection for mesial temporal lobe epilepsy: surgical indications, procedure, and postoperative seizure and memory outcomes

2013 ◽  
Vol 119 (5) ◽  
pp. 1098-1104 ◽  
Author(s):  
Takehiro Uda ◽  
Michiharu Morino ◽  
Hirotaka Ito ◽  
Noriaki Minami ◽  
Atsushi Hosono ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Verbal Memory ◽  
Memory Function ◽  
Mesial Temporal Lobe Epilepsy ◽  
Hippocampal Atrophy ◽  
Delayed Recall ◽  
Nonverbal Memory ◽  
Mesial Temporal Lobe ◽  
The Right

Object Amygdalohippocampectomy is a well-established, standard surgery for medically intractable mesial temporal lobe epilepsy (MTLE). However, in the case of MTLE without hippocampal atrophy or sclerosis, amygdalohippocampectomy is associated with decreased postoperative memory function. Hippocampal transection (HT) has been developed to overcome this problem. In HT the hippocampus is not removed; rather, the longitudinal hippocampal circuits of epileptic activities are disrupted by transection of the pyramidal layer of the hippocampus. The present study describes a less invasive modification of HT (transsylvian HT) and presents the seizure and memory outcomes for this procedure. Methods Thirty-seven patients with MTLE (18 men and 19 women; age range 9–63 years; 19 with surgery on the right side and 18 with surgery on the left side; seizure onset from 3 to 34 years) who were treated with transsylvian HT were retrospectively analyzed. All patients had left-side language dominance, and follow-up periods ranged from 12 to 94 months (median 49 months). Seizure outcomes were evaluated for all patients by using the Engel classification. Memory function was evaluated for 22 patients based on 3 indices (verbal memory, nonverbal memory, and delayed recall), with those scores obtained using the Wechsler Memory Scale–Revised. Patients underwent evaluation of the memory function before and after surgery (6 months–1 year). Results Engel Class I (completely seizure free) was achieved in 25 patients (67.6%). Class II and Class III designation was achieved in 10 (27%) and 2 patients (5.4%), respectively. There were differences in memory outcome between the sides of operation. On the right side, verbal memory significantly increased postoperatively (p = 0.003) but nonverbal memory and delayed recall showed no significant change after the operation (p = 0.718 and p = 0.210, respectively). On the left side, all 3 indices (verbal memory, nonverbal memory, and delayed recall) showed no significant change (p = 0.331, p = 0.458, and p = 0.366, respectively). Conclusions Favorable seizure outcome and preservation of verbal memory were achieved with transsylvian HT for the treatment of MTLE without hippocampal atrophy or sclerosis.

Earlier tachycardia for seizures originating from the right versus left hemisphere in a patient with bilateral mesial temporal lobe epilepsy

2020 ◽  
Vol 131 (9) ◽  
pp. 2168-2170 ◽  
Author(s):  
Kei Yanai ◽  
Seijiro Shimada ◽  
Naoto Kunii ◽  
Megumi Takasago ◽  
Kazuhiko Takabatake ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Left Hemisphere ◽  
Temporal Lobe ◽  
Mesial Temporal Lobe Epilepsy ◽  
Mesial Temporal Lobe ◽  
The Right

Exploring the Role of the Right Temporal Lobe in Person-specific Knowledge: A Case Study of Semantic Dementia Associated with Right Temporal Lobe Atrophy

2002 ◽  
Vol 2 (1) ◽  
pp. 54-61
Author(s):  
Shutaro Nakaaki ◽  
Junko Sato ◽  
Hikaru Nakamura ◽  
Shinichi Yoshida ◽  
Kyoko Furuhashi ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Semantic Dementia ◽  
Specific Knowledge ◽  
The Right ◽  
Lobe Atrophy

scholarly journals Temporal Lobe Epilepsy as a Unique Manifestation of Multiple Sclerosis

2003 ◽  
Vol 30 (3) ◽  
pp. 228-232 ◽  
Author(s):  
Antonio Gambardella ◽  
Paola Valentino ◽  
Angelo Labate ◽  
Grazia Sibilia ◽  
Francesca Ruscica ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Mri ◽  
Epileptic Seizures ◽  
Cortical Lesion ◽  
Temporal Region ◽  
Antiepileptic Medication ◽  
Long Term Follow Up

Objective:To report on five patients with temporal lobe epilepsy (TLE) as the unique manifestation of multiple sclerosis (MS).Methods:Among 350 consecutive MS patients, we identified 16/350 (4.6%) who also had epileptic seizures. Here, we review their electrophysiological and clinical features.Results:Five of these 16 patients (four female, one male; mean age 34.2 years; range 31 to 38) with MS and epileptic seizures had an extremely homogeneous clinical picture characterized by TLE as the unique manifestation of MS, even at long follow-up (mean: five years; range 4 to 10). In all patients, seizures started in the second or third decade. Brain MRI revealed at least one juxta-cortical lesion within the temporal region. Antiepileptic medication was always effective.Conclusions:The present study provides the first evidence of a peculiar form of MS characterized by TLE as the unique manifestation of the disease with no disability or MS relapses at long-term follow-up.

scholarly journals RIGHT VS. LEFT TEMPORAL LOBE SEMIOLOGY IN DEMENTIA: LESSONS FROM TWO CASES WITH FOCAL FRONTOTEMPORAL DEMENTIA SYNDROMES

2021 ◽  
Author(s):  
Vitor Arca ◽  
Pedro Albuquerque ◽  
Victor Correia ◽  
Amanda Pires ◽  
Hugo Araújo ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Temporal Lobe ◽  
Word Processing ◽  
Brain Mri ◽  
Cerebral Atrophy ◽  
Primary Progressive Aphasia ◽  
Left Temporal Lobe ◽  
Her Family ◽  
Mini Mental Status Examination ◽  
The Right

Background: Case 1: a 59-year old man presented to our service with 4 years of progressive cognitive and behavioral symptoms. He became forgetful and experienced difficulties managing his payments. After 4 years he could no longer recognise his relatives. Cognitive assessment showed a mini-mental status examination of 17/30. MRI and SPECT revealed respectively focal atrophy and hipoperfusion of the frontal regions and anterior right temporal lobe. Case 2: a 72-year-old woman was brought to evaluation with a 5-years history of progressive language and behavioral deterioration. Her family reported early speech errors and behavioral changes, with a marked aggressiveness, ritualistic behaviors and hyperorality. Cognitive evaluation revealed a MMSE of 6/30 mainly due to a relatively fluent afasia. Brain MRI showed asymmetric cerebral atrophy, more prominent in the anterior left temporal lobe. Objective: N/H Methods: N/H Results: N/H Conclusion: We describe two cases of suspected frontotemporal dementia (FTD) syndromes. The left ATL may receive proportionately more input from the lexical and phonological centers subserving word processing. The right ATL may receive more input from right-lateralized emotion processing hubs. Focal atrophy of the left anterior temporal lobe has been associated with the semantic type of primary progressive aphasia evolving to semantic dementia. In contrast, focal atrophy of the right temporal lobe has recently been described as a controversial entity reported as the right temporal variant of FTD.

scholarly journals Autosomal dominant temporal lobe epilepsy associated with heterozygous reelin mutation: 3 T brain MRI study with advanced neuroimaging methods

2019 ◽  
Vol 11 ◽  
pp. 39-42 ◽  
Author(s):  
Katarína Česká ◽  
Štefánia Aulická ◽  
Ondřej Horák ◽  
Pavlína Danhofer ◽  
Pavel Říha ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Autosomal Dominant ◽  
Brain Mri ◽  
Mri Study

Mental and behavioral disorders in temporal lobe epilepsy

Psihiatru ro ◽  
2019 ◽  
Vol 58 (3) (1) ◽  
pp. 23-27
Author(s):  
Diana Vulea ◽  
Simona Butnăraşu ◽  
Ciprian Băcilă
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Medical Condition ◽  
Focal Epilepsy ◽  
Epileptic Seizures ◽  
General Medical Condition ◽  
Legal Implications ◽  
The Right ◽  
Psychiatric Manifestations ◽  
Mental And Behavioral Disorders

The evolution of temporal lobe epilepsy often implies complex psychiatric manifestations, as the elements can be part of an aura, as well as of a psychiatric pathology of its own. This paper presents the case of a patient diagnosed with focal epilepsy of the right mesial temporal lobe, who subsequently developed psychotic disorder due to a general medical condition with medico-legal implications, treatment noncompliance and difficulties in controlling epileptic seizures.

scholarly journals Cortical Activation during a Cognitive Challenge in Patients with Chronic Temporal Lobe Epilepsy—A Dynamic SPECT Study

1993 ◽  
Vol 6 (4) ◽  
pp. 187-192
Author(s):  
P. J. Kirkpatrick ◽  
R. Morris ◽  
G. M. S. Syed ◽  
C. E. Polkey
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Single Photon ◽  
Photon Emission ◽  
Temporal Cortex ◽  
Cortical Activation ◽  
Word Memory ◽  
The Mean ◽  
Cognitive Challenge ◽  
The Right

In a pilot group of six patients suffering from chronic temporal lobe epilepsy, single photon emission computerized tomography (SPECT) has been used to image the changes in relative cerebral blood flow between rest (static scan) and conditions of cognitive activation (activated scan). The cognitive challenge used during activation comprised a test of word memory, and the performance was expressed as a word memory score (WMS) for each individual. An activation index (AI) was calculated from the mean normalized density counts in specific regions of interest (ROIs), and values obtained were analysed for correlation with the WMS. The mean AI was increased significantly in the right lateral temporal cortex, the right and left inferior frontal regions, the left temporal pole, and the right medial temporal cortex. A positive correlation with the WMS was found in the medial temporal cortices, and this relationship was significant for the right medial temporal ROI.

The right hemisphere’s contribution to discourse processing: A study in temporal lobe epilepsy

2017 ◽  
Vol 171 ◽  
pp. 31-41 ◽  
Author(s):  
Carolina Lomlomdjian ◽  
Claudia P. Múnera ◽  
Daniel M. Low ◽  
Verónica Terpiluk ◽  
Patricia Solís ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Discourse Processing ◽  
The Right
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