scholarly journals Aortic Valve Papillary Fibroelastoma Associated with Acute Cerebral Infarction: A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Nobuhiro Takeuchi ◽  
Masanori Takada ◽  
Koichi Fujita ◽  
Yoshiharu Nishibori ◽  
Takao Maruyama ◽  
...  
Keyword(s):  
Cerebral Infarction ◽  
Cardiac Tumor ◽  
Drug Regimen ◽  
Acute Cerebral Infarction ◽  
Papillary Fibroelastoma ◽  
Pathological Examination ◽  
Thromboembolic Events ◽  
Resected Tumor ◽  
History Of ◽  
Warfarin Potassium

An 80-year-old woman with a history of congestive heart failure, atrial fibrillation, and hypertension was transferred to our institution with hematemesis. Her drug regimen included 2 mg warfarin potassium/day to prevent thromboembolic events. Transthoracic echocardiography (TTE) performed at 78 years of age revealed a mass attached to the noncoronary cusp and a cardiac tumor was suspected. The patient declined surgery and was meticulously followed up with periodic TTE. Upper gastroendoscopy revealed a gastric ulcer with an exposed blood vessel; anticoagulant therapy was ceased. On day 15 of admission, acute cerebral infarction occurred. Heparin sodium and warfarin potassium were administered rapidly, and her symptoms improved. TTE revealed no alteration of the mobile, string-like mass attached to the noncoronary cusp. Cardiac tumor was considered the cause of cerebral infarction, and the patient consented to surgical therapy. Pathological examination of the resected tumor suggested papillary fibroelastoma (PFE). Although no guidelines exist for PFE management, a mobile, cardiac tumor necessitates surgical resection to prevent thromboembolic events, even when small in size.

Third ventricular choroid plexus papilloma with psychosis

1997 ◽  
Vol 87 (1) ◽  
pp. 103-105 ◽  
Author(s):  
Benjamin S. Carson ◽  
Jon D. Weingart ◽  
Michael Guarnieri ◽  
Paul G. Fisher
Keyword(s):  
Choroid Plexus ◽  
Behavioral Problems ◽  
Third Ventricle ◽  
Choroid Plexus Papilloma ◽  
Pathological Examination ◽  
Psychiatric Evaluation ◽  
Content Type ◽  
Resected Tumor ◽  
History Of ◽  
Plexus Papilloma

✓ This 9-year-old boy with a history of behavioral problems and worsening psychosis responded initially to treatment with haloperidol. However, a magnetic resonance image obtained as part of his psychiatric evaluation revealed an anterior third ventricle tumor and mild-to-moderate hydrocephalus. The resected tumor was found on pathological examination to be a choroid plexus papilloma. The patient had an uneventful postoperative course and remained free of psychosis or mood disorder at 1-year follow-up examination.

Familial Hypercholesterolemia and Cerebral Infarction - A Case Report

2021 ◽  
Author(s):  
Huajun Jiang ◽  
Qu Wei ◽  
Liang Zhanhua ◽  
Yang Jingjing
Keyword(s):  
Family History ◽  
Carotid Artery ◽  
Cerebral Infarction ◽  
Carotid Stenosis ◽  
Familial Hypercholesterolemia ◽  
Acute Cerebral Infarction ◽  
Ldlr Gene ◽  
History Of ◽  
The Right ◽  
Arterial Plaques

Abstract Background: Familial hypercholesterolemia has various presentations mostly including early-onset cardiovascular diseases, remarkable skin and tendon xanthomas. By comparison, Cerebral Infarction due to familial hypercholesterolemia is extremely rare. Case presentation: We present a 41-year-old man who was admitted to our hospital with dizziness, vertigo, slurred speech, weakness in his left limbs. He had family history of Hyperlipidemia in older sister . Head CT scan demonstrated multiple acute cerebral infarction in the right frontal and parietal lobes, and arterial plaques was found in the bifurcation of common carotid artery. The severe carotid stenosis was located in the initial segment of the right internal carotid artery. Histopathologic findings were consistent with xanthoma. Especially, molecular analysis of the LDLR gene was made, which identified heterozygous missense mutation in exon 12 of the LDLR gene. The final diagnosis of cerebral infarction associated with familial hypercholesterolemia was made. The patient was referred to a nutritionist for dietary advice, and was treated with Tab. Finally, the patient recovered well. The symptoms of brain infarct vanished and no recurrence occurred during follow-up.Conclusions: In the present case, the acute cerebral infarction is most likely due to hypercholesterolemia, as his family history of hypercholesterolemia, and arterial plaques and severe carotid stenosis was found by CTA. This case highlights the importance of the early diagnosis and treatment of hypercholesterolemia, which may help in preventing the development of cardiovascular and cerebrovascular diseases.

scholarly journals Papillary Fibroelastoma of the Right Ventricular Free Wall

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Tetsuya Niino ◽  
Satoshi Unosawa
Keyword(s):  
Cardiac Tumor ◽  
Main Pulmonary Artery ◽  
Tumor Resection ◽  
Papillary Fibroelastoma ◽  
Free Wall ◽  
Right Ventricular Free Wall ◽  
Postoperative Course ◽  
Resected Tumor ◽  
Benign Cardiac Tumor ◽  
The Right

Papillary fibroelastoma is a rare benign cardiac tumor that usually arises from the valvular endocardium and its development in the cardiac chambers is extremely rare. A 52-year-old woman complained of palpitations and echocardiography revealed a cardiac tumor. Resection was performed via the right ventricle and main pulmonary artery under cardiopulmonary bypass. Histological examination of the resected tumor showed that it was a papillary fibroelastoma. The patient’s postoperative course was unremarkable and no complications have been detected on followup.

ANALYSIS OF DRUG THERAPY FOR ACUTE CEREBRAL INFARCTION AT HUE CENTRAL HOSPITAL FROM AUGUST 2010 TO JUNE 2011

2011 ◽  
pp. 43-52
Author(s):  
Thi Ha Vo ◽  
Thi Kim Huyen Hoang ◽  
Khanh Hoang
Keyword(s):  
Drug Interaction ◽  
Drug Therapy ◽  
Cerebral Infarction ◽  
Acute Cerebral Infarction ◽  
Central Hospital ◽  
Neuroprotective Drugs ◽  
History Of ◽  
The Mean ◽  
Drug Drug Interaction ◽  
Ulcer Prophylaxis

Objectives: The cerebral infarction is a complex clinical emergency and the application of guidelines of treatment in each health establishment varies. The study was conducted with two main objectives: (1) Identify the profile of patients and (2) Analyze the drug therapy in patients with acute cerebral infarction. Materials and Methods: A prospective, descriptive study of 94 in patients with acute cerebral infarction treated at the Hue Central Hospital from 08/2010 to 06/2011 was conducted; Results: the mean age was 68.6 ± 15.5 years (range 16-101), 73.4% had hypertension at admission, the most commonly risk factors included pre-existing hypertensions (59.6%), cardiovascular diseases (28.7%) and a history of cerebral vascular accident or TIA (26.6%). Four groups of drugs used the most frequently were: neuroprotective drugs (95.8%), antibiotics (85.1%), vitamins - minerals (84.0%), drugs for peptic ulcer prophylaxis (74.5%). A total of three cases of ADR were reported. 86.2% of patients received potential drug-drug interaction pairs and the mean number of drug-drug interaction pairs per patient was 4.9 ± 2.4. Conclusions: The treatment of patients with cerebral infarction was complex, often has to combine many different classes of drugs, some have narrow therapeutic ranges, which were indicated in patients with multiple pathologies that increased the risk of drug-related problems. It is necessary to monitor closely the drug therapeutics.

The Diagnostic Value of Pericardial Fluid and Pericardial Biopsy: Single Center Experiences

2016 ◽  
Vol 19 (1) ◽  
pp. 023 ◽  
Author(s):  
Mehmet Yildirim ◽  
Recep Ustaalioglu ◽  
Murat Erkan ◽  
Bala Basak Oven Ustaalioglu ◽  
Hatice Demirbag ◽  
...  
Keyword(s):  
Pericardial Effusion ◽  
Thoracoscopic Surgery ◽  
Pericardial Tamponade ◽  
Pericardial Fluid ◽  
Pathological Examination ◽  
Common Disease ◽  
Pericardial Window ◽  
Surgical Interventions ◽  
History Of ◽  
Recurrent Pericardial Effusion

<strong>Background:</strong> Patients with recurrent pericardial effusion and pericardial tamponade are usually treated in thoracic surgery clinics by VATS (video-assisted thoracoscopic surgery) or open pericardial window operation. The diagnostic importance of pathological evaluation of the pericardial fluid and tissue in the same patients has been reported in few studies. We reviewed pathological examination of the pericardial tissue and fluid specimens and the effect on the clinical treatment in our clinic, and compared the results with the literature. <br /><strong>Methods:</strong> We retrospectively analyzed 174 patients who underwent pericardial window operation due to pericardial tamponade or recurrent pericardial effusion. For all patients both the results of the pericardial fluid and pericardial biopsy specimen were evaluated. Clinicopathological factors were analyzed by using descriptive analysis. <br /><strong>Results:</strong> Median age was 61 (range, 20-94 years). The most common benign diagnosis was chronic inflammation (94 patients) by pericardial biopsy. History of malignancy was present in 28 patients (16.1%) and the most common disease was lung cancer (14 patients). A total of 24 patients (13.8%) could be diagnosed as having malignancy by pericardial fluid or pericardial biopsy examination. The malignancy was recognized for 12 patients who had a history of cancer; 9 of 12 with pericardial biopsy, 7 diagnosed by pericardial fluid. Twelve of 156 patients were recognized as having underlying malignancy by pericardial biopsy (n = 9) or fluid examination (n = 10), without known malignancy previously. <br /><strong>Conclusion:</strong> Recurrent pericardial effusion/pericardial tamponade are entities frequently diagnosed, and surgical interventions may be needed either for diagnosis and/or treatment, but specific etiology can rarely be obtained in spite of pathological examination of either pericardial tissue or fluid. For increasing the probability of a specific diagnosis both the pericardial fluid and the pericardial tissues have to be sent for pathologic examination.

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