scholarly journals Relation of Visceral and Subcutaneous Adipose Tissue to Bone Mineral Density in Chinese Women

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ling Wang ◽  
Wei Wang ◽  
Li Xu ◽  
Xiaoguang Cheng ◽  
Yimin Ma ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Adipose Tissue ◽  
Bone Mineral ◽  
Chinese Women ◽  
Quantitative Computed Tomography ◽  
Cross Sectional Study ◽  
Mineral Density ◽  
Trabecular Bone Mineral Density ◽  
Cross Sectional ◽  
Subcutaneous Adipose

The relationship between adipose and bone tissues is still being debated. The purpose of our study was to evaluate whether the distribution and volume of abdomen adipose tissue are correlated to trabecular bone mineral density in the lumbar spine. In this cross-sectional study, 320 Chinese women, being divided into two groups according to age ≥55 years and <55 years, were evaluated with quantitative computed tomography (QCT) of the spine to simultaneously evaluate the average trabecular BMD of L2–L4, VAT, and SAT. Possible covariates of height, weight, age, and comorbidities were considered. In the <55-year-old sample, multiple linear regression analyses indicated that VAT volume was negatively correlated to trabecular BMD (Pvalue = 0.0003) and SAT volume had no correlation to trabecular BMD. In contrast, there was no significant correlation between VAT or SAT and BMD in the ≥55-year-old sample. Our results indicate that high VAT volume is associated with low BMD in Chinese women aged <55 years and SAT has no relation with BMD.

scholarly journals Reduction of trabecular and cortical volumetric bone mineral density at the proximal femur in patients with acromegaly

2016 ◽  
Vol 174 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Elena Valassi ◽  
Iris Crespo ◽  
Jorge Malouf ◽  
Jaume Llauger ◽  
Anna Aulinas ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Proximal Femur ◽  
Disease Duration ◽  
Quantitative Computed Tomography ◽  
Cross Sectional Study ◽  
Volumetric Bone Mineral Density ◽  
Inverse Association ◽  
Mineral Density ◽  
Cross Sectional

ObjectiveData on dual energy absorptiometry (DXA)-measured bone mineral density (BMD) at the level of the total hip (TH) and femoral neck (FN) in patients with acromegaly (ACRO) are conflicting. Increase in bone size associated with ACRO may limit the reliability of DXA. Our objective is to evaluate trabecular and cortical volumetric BMD (vBMD) across the proximal femur in ACRO patients.DesignCross sectional study in a clinical research center.PatientsThirty-five ACRO patients (19 males; mean age, 48±7 years; BMI, 27.5±4.4 kg/m2; 17 with active disease) and 35 age, gender, and BMI-matched controls.ResultsvBMD was assessed by quantitative computed tomography at the level of the TH, FN, trochanter (TR), and intertrochanteric (IT). Trabecular vBMD was lower in both total and active ACRO as compared with controls (P<0.01). Cortical vBMD was lower in ACRO patients (active and controlled) vs controls at both TH and TR sites (P<0.05). These findings were confirmed when only eugonadal patients were analyzed. Both total cross sectional area (CSA) and average cortical thickness (ACT) were greater in ACRO patients vs controls (P<0.05). An inverse association between disease duration and trabecular vBMD at TH (r=−0.42, P=0.023) and IT (r=−0.41, P=0.026) was also found.ConclusionBoth cortical and trabecular vBMD are reduced at the proximal femur in ACRO patients, regardless of gender, gonadal status, and disease activity. Disease duration is negatively associated with trabecular vBMD at the TH and IT.

scholarly journals Somatic maturation and the relationship between bone mineral variables and types of sports among adolescents: cross-sectional study

2017 ◽  
Vol 135 (3) ◽  
pp. 253-259 ◽  
Author(s):  
Ricardo Ribeiro Agostinete ◽  
Igor Hideki Ito ◽  
Han Kemper ◽  
Carlos Marcelo Pastre ◽  
Mário Antônio Rodrigues-Júnior ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Peak Height ◽  
Cross Sectional Study ◽  
Height Velocity ◽  
Whole Body ◽  
Sectional Study ◽  
Peak Height Velocity ◽  
Mineral Density ◽  
Cross Sectional

ABSTRACT CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS: The study was composed of 93 adolescents (12 to 16.5 years old), divided into three groups: no-sport group (n = 42), soccer/basketball group (n = 26) and swimming group (n = 25). Bone mineral density and content were measured using dual-energy x-ray absorptiometry and somatic maturation was estimated through using peak height velocity. Data on training load were provided by the coaches. RESULTS: Adolescents whose PHV occurred at an older age presented higher bone mineral density in their upper limbs (P = 0.018). After adjustments for confounders, such as somatic maturation, the swimmers presented lower values for bone mineral density in their lower limbs, spine and whole body. Only the bone mineral density in the upper limbs was similar between the groups. There was a negative relationship between whole-body bone mineral content and the weekly training hours (β: -1563.967; 95% confidence interval, CI: -2916.484 to -211.450). CONCLUSION: The differences in bone variables attributed to sport practice occurred independently of maturation, while high training load in situations of hypogravity seemed to be related to lower bone mass in swimmers.

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