scholarly journals Cortical Anaplastic Ependymoma with Significant Desmoplasia: A Case Report and Literature Review

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Alaa Eldin Elsharkawy ◽  
Raid Abuamona ◽  
Markus Bergmann ◽  
Shadi Salem ◽  
Evariste Gafumbegete ◽  
...  

Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare. We present a rare case of a 25-year-old male who presented with generalized convulsions. Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion. Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle. The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia. A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed. There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas. Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.

2005 ◽  
Vol 19 (4) ◽  
pp. 181-190 ◽  
Author(s):  
Chien-Kuo Wang ◽  
Tsyh-Jyi Hsieh ◽  
Twei-Shiun Jaw ◽  
Jau-Nan Lin ◽  
Gin-Chung Liu ◽  
...  

A technique calledin vivomagnetic resonance spectroscopy (MRS) can be performed along with magnetic resonance imaging (MRI) to obtain information about the chemical content of musculoskeletal lesions. This information can be used for several clinical applications, such as improving the accuracy of lesion diagnosis and monitoring the response to cancer therapies. Initial MRS studies of musculoskeletal tumors show promising results, and the technique has been incorporating into the MRI routine protocols. This article introduces1H MRS of the musculoskeletal tumors, reviews the literature, discusses current methods and technical issues, and describes applications for treatment monitoring and lesion diagnosis.


2002 ◽  
Vol 30 (2) ◽  
pp. 232-237 ◽  
Author(s):  
R. S. Richardson ◽  
E. A. Noyszewski ◽  
L. J. Haseler ◽  
S. Bluml ◽  
L. R. Frank

Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) are both powerful, non-invasive methodologies and, as such, offer great potential to investigate both human biochemistry and human physiology, and ultimately to contribute significantly to the field of medicine. Consequently there has been much effort devoted to fostering the evolution of these methodologies into distinct and applicable techniques. Here we will highlight several MRI and MRS techniques for the assessment of human biochemistry and physiology that ultimately may provide useful clinical assessments and diagnoses of various muscular and cardiovascular pathologies. Specifically, the evolving techniques that will be discussed are: (1) 1H MRS of myoglobin to assess the intracellular partial pressure of O2, (2) 31P MRS to assess metabolic capacity, and (3) the combination of 31P chemical shift imaging to assess local metabolic demand (oxygen uptake; o2) with arterial spin labelling to assess local perfusion (blood flow; ), in an effort to characterize the elusive spatial matching of skeletal muscle (/o2).


1990 ◽  
Vol 157 (S9) ◽  
pp. 56-65 ◽  
Author(s):  
John L. Waddington ◽  
Eadbhard O'Callaghan ◽  
Conall Larkin ◽  
Oonagh Redmond ◽  
John Stack ◽  
...  

In this new era of structural and functional neuroimaging technologies, it is the unsurpassed anatomical resolution of magnetic resonance imaging (MRI) (Andreasen, 1989; and Besson, this supplement) that has resulted in a new generation of studies on cerebral morphology in schizophrenia. With the recent development of whole-body magnets of very high (⩾ 1.5T) and uniform field strength, it has become possible to extend the scope of this approach to include measurement of certain fundamental neurochemical processes, via magnetic resonance spectroscopy (MRS: Hubesch et al, 1989; Lock et al, this supplement). The purpose of this article is to introduce and review critically the existing literature on the application of MRI and MRS to schizophrenia, and to give a preliminary account of some of our own recent studies in these areas.


2000 ◽  
Vol 10 (4) ◽  
pp. 335-337 ◽  
Author(s):  
G. Rebolleda ◽  
M. Suárez Figueroa ◽  
F.J. Muñoz-Negrete ◽  
A. Rocamora

Purpose To report the development of a cavitary choroidal melanoma in a patient with nevus of Ota and describe its magnetic resonance imaging (MRI) features. Patient A 66-year-old man with right oculodermal melanocytosis and an ipsilateral choroidal cavitary melanoma was seen. Diagnosis was suspected on the clinical, ultrasonographic and MRI findings. Results T1-weighted image showed a hyperintense solid mass containing hypointense cystic-like spaces delineated by hyperintense septa with respect to the vitreous. The reverse image was observed on T2-weighted images. A choroidal melanoma comprising epithelioid and spindle cells with multilocular cavities was documented histopathologically. Conclusions There may be an association between cavitary melanoma and nevus of Ota. Characteristic MRI findings could be helpful in the differential diagnosis of cavitary uveal melanoma.


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