scholarly journals Risk Factors for Hearing Loss in Children following Bacterial Meningitis in a Tertiary Referral Hospital

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Benson Wahome Karanja ◽  
Herbert Ouma Oburra ◽  
Peter Masinde ◽  
Dalton Wamalwa
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Healthcare Providers ◽  
Sensorineural Hearing ◽  
Tertiary Referral Hospital ◽  
Hearing Function ◽  
Children With Hearing Loss ◽  
Audiologic Testing

Objective. This study aimed to examine hearing function in children admitted with bacterial meningitis to determine the risk factors for sensorineural hearing loss.Setting. The study was conducted in the audiology unit and paediatric wards of Kenyatta National Hospital.Subjects and Methods. The study involved 83 children between the ages of six months and twelve years admitted with bacterial meningitis. The median age for the children examined was 14. On discharge they underwent hearing testing to evaluate for presence and degree of hearing loss.Results. Thirty six of the 83 children (44.4%) were found to have at least a unilateral mild sensorineural hearing loss during initial audiologic testing. Of the children with hearing loss, 22 (26.5%) had mild or moderate sensorineural hearing loss and 14 (16.9%) had severe or profound sensorineural hearing loss. Significant determinants identified for hearing loss included coma score below eight, seizures, cranial nerve neuropathy, positive CSF culture, and fever above 38.7 degrees Celsius.Conclusions. Sensorineural hearing loss was found to be highly prevalent in children treated for bacterial meningitis. There is need to educate healthcare providers on aggressive management of coma, fever, and seizures due to their poor prognostic value on hearing.

scholarly journals Sensorineural hearing loss after bacterial meningitis in children

2017 ◽  
Vol 4 (46) ◽  
pp. 14-19
Author(s):  
Aliya Seidullayeva ◽  
Gulnar Zhaxylykova ◽  
Dinagul Bayesheva ◽  
Raisa Sundetova ◽  
Bulat Aitzhanov ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Meningitis In Children

scholarly journals Cisplatin Ototoxicity: Examination of the Impact of Dosing, Infusion Times, and Schedules In Pediatric Cancer Patients

2021 ◽  
Vol 11 ◽  
Author(s):  
Miranda L. Camet ◽  
Anne Spence ◽  
Susan S. Hayashi ◽  
Ningying Wu ◽  
Jennifer Henry ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Model Building ◽  
Significant Risk ◽  
The Body ◽  
Sensorineural Hearing ◽  
Cycle Number ◽  
Pediatric Cancer Patients ◽  
The Impact

BackgroundSensorineural hearing loss is a well-known side effect of cisplatin (CDDP). There is limited research on the effect of dosing, infusion times, and schedules of cisplatin administration and their impact on hearing loss.MethodsA retrospective review of 993 pediatric patients’ medical and audiological charts from August 1990 to March 2015 was conducted using stringent inclusion criteria to characterize patients with hearing loss. 248 of these patients received CDDP. Of these, 216 patients had sufficient CDDP infusion data to assess for sensorineural hearing loss attributable to CDDP and its associated risk factors. Chart reviews were performed to extract clinical data including CDDP dosing information. Demographic and clinical characteristics were summarized by descriptive statistics, and univariate and multivariate logistic regressions were performed to examine the relationship between hearing loss and specific parameters of cisplatin administration (amount infused per dose, prescribed infusion time, total number of doses, number of doses per cycle, number of cycles, cumulative cisplatin exposure). Stepwise variable selection procedure was performed in the multivariate model building to extract the best subset of risk factors for the prediction of hearing loss and worsening ototoxicity grade using an established ototoxicity grading scale from the International Society of Pediatric Oncology (SIOP).ResultsA total of 153 patients with complete medical and audiologic data were evaluable for analysis. Hearing loss was identified in 72.6% of the patients. Multivariate analysis revealed that age [OR=0.90 (0.84-0.97), p-value=0.0086], radiation to any part of the body, [OR=3.20 (1.29-7.93), p-value=0.012], amount infused per dose (mg/m2) [OR=1.018 (1.002-1.033), p-value=0.029], and cumulative cisplatin exposure (mg/m 2) [OR=1.004 (1-1.008), p-value=0.027] were associated with hearing loss. Similar associations were also found between these risk factors and worsening SIOP grade.ConclusionIn one of the largest studies examining the influence of CDDP dosing and schedules on hearing loss, we found the amount of CDDP infused per dose is a significant risk factor. Considerations in designing regimens that reduce the amount of CDDP infused per dose may reduce the risk of hearing loss. Randomized prospective trials are needed.

scholarly journals Frequency of sensorineural hearing loss in children with bacterial meningitis.

2020 ◽  
Vol 27 (12) ◽  
pp. 2729-2733
Author(s):  
Rabia Saleem Safdar ◽  
M Faisal Mehar ◽  
Madiha Naz ◽  
Afsheen Asghar Khan ◽  
Nusrat Buzdar ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Cross Sectional Study ◽  
Sensorineural Hearing ◽  
Outcome Variable ◽  
Cross Sectional ◽  
And Gender ◽  
Evoked Response Audiometry ◽  
Study Setting

Objectives: To determine the frequency of sensorineural hearing loss (SNHL) in children with bacterial meningitis. Study Design: Cross Sectional study. Setting: Department of Paediatric Medicine Nishtar Hospital, Multan. Period: October 2019 to March 2020. Material & Methods: The study was conducted after permission from ethical committee. A total of 151 patients admitted with bacterial meningitis were enrolled. Apart from the presenting complaints, necessary information like the age and gender were noted. Examination of the child was done to assess the condition of child. Brainstem evoked response audiometry (BERA) test was performed before discharge of the patient from the hospital. The outcome variable that is SNHL in bacterial meningitis assessed by BERA test was noted in a specifically designed Performa. Results: Out of total of 151 patients, males were 83 (55%) while females 68 (45%). Overall mean age was 11.85+6.12 months. SNHL was found in 26 (17.2%) children. There was no significant effect of age or gender on the frequencies of SNHL. Conclusion: SNHL is a frequently encountered complication in our population of children with bacterial meningitis. SNHL should be carefully sought out and properly diagnosed in all the patients presenting with bacterial meningitis.

Risk Factors for Sensorineural Hearing Loss in Children

2012 ◽  
Vol 63 (5) ◽  
pp. 382-390 ◽  
Author(s):  
Faustino Núñez-Batalla ◽  
Germán Trinidad-Ramos ◽  
José Miguel Sequí-Canet ◽  
Valentín Alzina De Aguilar ◽  
Carmen Jáudenes-Casaubón
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing

Hearing and Neurodevelopmental Outcome in Survivors of Persistent Pulmonary Hypertension of the Newborn

PEDIATRICS ◽  
1992 ◽  
Vol 90 (3) ◽  
pp. 392-396 ◽  
Author(s):  
Mary-Joan Marron ◽  
Maria A. Crisafi ◽  
John M. Driscoll ◽  
Jen-Tien Wung ◽  
Yvonne T. Driscoll ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Neurodevelopmental Outcome ◽  
Supplemental Oxygen ◽  
Sensorineural Hearing ◽  
Persistent Pulmonary Hypertension ◽  
Arterial Oxygen ◽  
Abnormal Chest ◽  
Audiologic Testing

Thirty-four infants who had a diagnosis of severe persistent pulmonary hypertension of the newborn at birth (alveolar-arterial oxygen difference > 600) were treated without paralysis or hyperventilation to induce alkalosis. All survived. Twenty-seven of these 34 eligible infants (79%) underwent neurologic, intelligence, and audiologic testing between 10 months and 6 years of age. Children who were younger than 1 year of age at the initial hearing test were retested after they reached 2 years of age. The average IQ was within the normal range (mean = 96.23). None had sensorineural hearing loss. Severe neurologic abnormalities were seen in 4 children, 3 of whom had been severely asphyxiated at birth (determined by biochemical criteria). Mild neurologic abnormalities were observed in 5 children. Two infants had bronchopulmonary dysplasia because they required supplemental oxygen for 29 and 66 days, respectively, and had abnormal chest roentgenograms; 1 patient takes intermittent doses of albuterol (Ventolin) and neither currently requires supplemental oxygen. This study of 27 infants with severe persistent pulmonary hypertension of the newborn suggests that conservative management without induced alkalosis or respiratory paralysis is accompanied by no sensorineural hearing loss and a good neurologic outcome.

Frequency of Sensorineural Hearing Loss among Children with Bacterial Meningitis

2021 ◽  
Vol 15 (8) ◽  
pp. 1827-1828
Author(s):  
Faiza Gohar ◽  
Syed Sajid Munir ◽  
Sami Ul Haq
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Sample Size ◽  
Study Design ◽  
Teaching Hospital ◽  
Sensorineural Hearing ◽  
Acute Bacterial Meningitis ◽  
Cross Sectional ◽  
Hearing Assessment

Aim: Frequency of sensorineural hearing loss among children presenting with acute bacterial meningitis. Study design: Pediatric wards of Khyber Teaching Hospital, Peshawar with the help of audiology department of Khyber teaching hospital, Peshawar Study design & duration: Descriptive cross sectional study. 5 months from 23/10/2018 to 23/03/2019. Sample size: Sample size was 149 using 44.4% proportions SNHL among children with bacterial meningitis, 95% confidence level and 8% absolute precision using WHO sample size calculations. Methodology: 149 cases i.e. 90 males and 59 females were included with age of 02 to 144 months. All were with diagnosis of bacterial meningitis. Lab tests and CSF examination was performed. The assessment of hearing was done before discharge in the form of BERA and PTA. All findings of hearing assessment was entered in Performa. Results: In the study, mean± SD of age was 28± 35.7. Moreover, 60.4% were males and 39.6% were females. 10(6.7%) of the 149 cases have sensorineural hearing loss while 139(93.3%) were having normal on hearing assessment. Conclusion: Sensorineural hearing loss in patients with bacterial meningitis was 6.7%. Keywords: Sensorineural Hearing Loss, Meningitis, Bacterial Meningitis

scholarly journals Clinical Profile and Outcome of Acute Encephalitis Syndrome in Dhulikhel Hospital of Nepal

2013 ◽  
Vol 32 (3) ◽  
pp. 201-205 ◽  
Author(s):  
Srijana Dongol ◽  
Shreema Shrestha ◽  
Narayan Shrestha ◽  
J Adhikari
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Clinical Signs ◽  
Viral Meningitis ◽  
Sensorineural Hearing ◽  
Subdural Effusion ◽  
Eosinophilic Meningitis ◽  
Acute Encephalitis Syndrome ◽  
Acute Encephalitis

Introduction: Acute encephalitis syndrome (AES) is a constellation of clinical signs and or symptoms i.e. acute fever with acute change in mental status. AES may be present as encephalitis, meningoencephalitis or meningitis. It can be associated with severe complication, including impaired consciousness, seizure, limb paresis or death. Materials and Methods: Study consisted of retrospective analysis of hospital records of children up to 16 years of age admitted with diagnosis of AES in the department of Paediatrics Dhulikhel Hospital, Kathmandu University Teaching Hospital, Dhulikhel Kavre from January 2010 to December 2011. Results: During the two years (January 2010 to December 2011), 47 patients of AES were admitted. Among the admitted cases there were 34 male and 13 female patients. Meningitis cases were 29, encephalitis cases were 14 and 4 meningoencephalitis cases. Among the meningitis cases, viral meningitis accounted for 12, bacterial meningitis accounted for 15 and 1 tubercular meningitis.One was eosinopilic meningitis in which the causative organism was found to be fasciolosis by ELISA. Viral encephalitis was found to be the most common cause of encephalitis. Sensorineural hearing loss was seen in 3 cases, subdural effusion in 1 and hydrocephalus in 1. One patient had intracranial hemorrhage with hemiparesis as a complication of eosinophilic meningitis. Conclusion: Acute encephalitis syndrome is one of the most common causes of PICU admission in Dhulikhel hospital. Bacterial meningitis was common among the acute encephalitis syndrome followed by viral meningitis. One case of eosinophilic meningitis with intracranical hemorrhage and hemiparesis was found. Sensorineural hearing loss was found to be commonest complication. DOI: http://dx.doi.org/10.3126/jnps.v32i3.6683 J. Nepal Paediatr. SocVol.32(3) 2012 201-205

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