scholarly journals Active Case Finding of Pulmonary Tuberculosis through Screening of Respiratory Symptomatics Using Sputum Microscopy: Is It Time to Change the Paradigm?

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Eva Carolina del Portillo-Mustieles ◽  
Rafael Laniado-Laborín
Keyword(s):  
Pulmonary Tuberculosis ◽  
Sputum Sample ◽  
Upper Airway ◽  
Case Finding ◽  
Active Case Finding ◽  
Active Case ◽  
Sputum Microscopy ◽  
Two Samples ◽  
Airway Symptoms ◽  
Positive Smear

Background.One of the main strategies for the early detection of pulmonary tuberculosis (PTB) is through the screening of individuals with symptoms compatible with PTB. Although this is programmatic strategy for active case finding, its yield is not well known.Objective.To determine the yield of pulmonary tuberculosis active case finding through the screening of respiratory symptomatic (RS) patients at a general hospital.Methods.RS patients were defined as subjects complaining of cough and/or sputum for a period of 2 or more weeks. Outpatients and their companions were approached while they waited in the outpatient care areas of the hospital to detect RS. Two samples from different days or 2 samples taken 2 hours apart on the same day were collected.Results.122 RS patients were identified. Fifty-seven patients (46.7%) had at least one sputum sample analyzed. Three patients presented a positive smear and 2 were culture positive; neither had upper airway symptoms. None of the patients with productive cough and upper airway symptoms had a positive smear (). Only 19 (33.3%) returned to the laboratory to retrieve their results.Conclusion.Current strategy to screen RS patients based only on clinical data has a low compliance. Specific strategies to increase compliance (removal of barriers, incentives, etc.) should be implemented.

scholarly journals Blood-based host biomarker diagnostics in active case finding for pulmonary tuberculosis: A diagnostic case-control study

2021 ◽  
pp. 100776
Author(s):  
Flora Martinez Figueira Moreira ◽  
Renu Verma ◽  
Paulo Cesar Pereira dos Santos ◽  
Alessandra Leite ◽  
Andrea da Silva Santos ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Case Control Study ◽  
Case Control ◽  
Case Finding ◽  
Active Case Finding ◽  
Active Case ◽  
Control Study

Mass screening for active case finding of pulmonary tuberculosis in the Russian Federation: how to save costs

2019 ◽  
Vol 23 (7) ◽  
pp. 830-837
Author(s):  
E. Bogdanova ◽  
O. Mariandyshev ◽  
S. G. Hinderaker ◽  
E. Nikishova ◽  
A. Kulizhskaya ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Mass Screening ◽  
Russian Federation ◽  
Case Finding ◽  
Active Case Finding ◽  
Active Case ◽  
The Russian Federation

scholarly journals Active detection of tuberculosis: tackling the problem head on in the remote area of Andaman and Nicobar Islands

2019 ◽  
Vol 6 (8) ◽  
pp. 3314
Author(s):  
Samarendra Prasanna Burma ◽  
Gunda Jahnavi ◽  
Pappachen Lal ◽  
Pandurang V. Thatkar
Keyword(s):  
Case Finding ◽  
Nucleic Acid Amplification ◽  
Sputum Smear ◽  
Active Case Finding ◽  
Community Based ◽  
Cross Sectional ◽  
X Ray ◽  
Active Case ◽  
Sputum Microscopy ◽  
Team Activity

Background: Community based active case finding for tuberculosis (TB) is an essential step in the fight forward for eliminating TB. One of the steps in targeting TB intervention is early diagnosis and treatment of patients by reducing the reservoir of infection in the community. Active case finding (ACF) targeting the entire population by house to house survey was done in Nicobar district of these islands.Methods: A community-based, cross-sectional, descriptive study was conducted with the trained mobile teams from 17.07.2017 to 31.07.2017 in the Nicobar District. The algorithm of the case detection included screening patients by symptoms, then by sputum microscopy for confirmation. X-ray was done in patients who were symptomatic but sputum negative. If both smear and chest X-ray results were negative but still symptomatic, then cartridge-based nucleic acid amplification test (CBNAAT) was done.Results: A total population of 18526 was mapped of which 14784 (79.8) could be screened. A total of 209 people were identified by the mobile teams with symptoms who were examined by sputum microscopy. Among them 7 cases were identified to be sputum smear positive, 2 X-ray positive and 2 were diagnosed by CBNAAT.Conclusions: This study shows that the active case finding method is feasible and acceptable by the community. The results obtained are encouraging for the implementation of ACF through mobile team activity in all these islands in order to meet the target of WHO’s End TB Strategy.

scholarly journals Impact of Active Case Finding on Treatment Outcomes in Adult Pulmonary Tuberculosis Patients

2021 ◽  
Vol 99 (7) ◽  
pp. 33-40
Author(s):  
S. А. Sterlikov ◽  
V. B. Gаlkin ◽  
B. M. Mаliev ◽  
А. А. Shirokovа ◽  
V. А. Khorotetto ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Treatment Outcomes ◽  
Lung Tissue ◽  
Case Finding ◽  
Adjusted Relative Risk ◽  
Active Case Finding ◽  
Tissue Destruction ◽  
Tuberculosis Patients ◽  
Active Case ◽  
Risk Of Death

The objective: to assess the effect of active finding of tuberculosis cases on the frequency of bacterial excretion, lung tissue destruction, and treatment outcomes.Subjects and Methods. The characteristics of adult patients (newly detected - new cases and those with relapsed pulmonary tuberculosis) were studied in 2 phases: a) 1,404 cases, including 814 actively found, at detection; b) the outcomes of the completed first course of chemotherapy in 946 patients, including 565 actively detected, registered for treatment in 2017 and 2018. Adjusted relative risk (aOR) and statistical significance of differences were calculated.Results. Patients detected actively versus those detected by self presentation to a medical unit had a lower level of positive results of smear microscopy (aOR = 2.7; p < 0.01) and lung tissue destruction (aOR = 1.4; p = 0.01), but the level of positive culture was equal (aOR = 0.9; p = 0.6).  Active case finding had no effect on treatment failure rate but if a patient is HIV negative and young, it reduced the risk of death in tuberculosis patients during treatment (aOR = 0.3; p < 0.01). Active case finding, along with no history of previous treatment, negative HIV status, and older age were inversely associated with treatment interruption (aOR = 0.3; p < 0.01).

scholarly journals Active Case Finding of Pulmonary Tuberculosis among Prison Inmates in Aba Federal Prison, Abia State, Nigeria

2015 ◽  
Vol 05 (01) ◽  
pp. 57-62 ◽  
Author(s):  
Emmanuel O. Ekundayo ◽  
Okorie Onuka ◽  
Gidado Mustapha ◽  
Mazi Geoffrey
Keyword(s):  
Pulmonary Tuberculosis ◽  
Case Finding ◽  
Prison Inmates ◽  
Active Case Finding ◽  
Federal Prison ◽  
Active Case
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