scholarly journals Osteosarcoma: Evolution of Treatment Paradigms

Sarcoma ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Norman Jaffe ◽  
Ajay Puri ◽  
Hans Gelderblom

This paper reviews the contribution of chemotherapy in the conquest of osteosarcoma. It discusses how the treatment of osteosarcoma has evolved over the last five decades, resulting in a more than fivefold increase in survival. Though the initial improvements in survival were dramatic, essentially there has been no change in the outlook for this disease over the past 30 years. The paper also highlights the necessity of a multidisciplinary approach to combat this disease and stresses the need to explore newer treatment agents in order to build on the lessons learnt from the past while striving to achieve greater levels of success.

2021 ◽  
Vol 30 (10) ◽  
pp. 580-587
Author(s):  
Ajay Asokan ◽  
Joanna Baawa-Ameyaw ◽  
Babar Kayani ◽  
Ganan T Radhakrishnan ◽  
Ahmed A Magan ◽  
...  

Robotic-arm assisted arthroplasty (RAA) has gained popularity over the past decade because of its ability to provide more accurate implant positioning with less surgical trauma than conventional manual arthroplasty. It has shown better early functional outcomes, less postoperative pain and shorter inpatient stays. A multidisciplinary approach is crucial in improving overall outcomes and ensuring this technology is implemented efficiently and safely, but there is limited published literature on the nursing considerations for managing patients undergoing RAA. This article aims to provide a pragmatic approach for nursing care in the pre-, intra-, and postoperative phases of RAA.


2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Maria Archontaki ◽  
Dimitris P. Korkolis ◽  
Niki Arnogiannaki ◽  
Stelios Hatzijiannis ◽  
Panagiotis Dendrinos ◽  
...  

Solitary fibrous tumour (SFT) is a rare oncological entity that most often arises in the pleura. Over the past 10 years, the tumour has been described at numerous extrapleural locations. We present the case of a 42-year-old female Caucasian patient with an extrapleural SFT located at the anterior thoracic wall for 22 years, with atypical histological characteristics and clinical features of malignancy. Management consisted of a wide surgical resection, plastic reconstruction, and postoperative radiotherapy. Although extrapleural SFT usually behaves as a benign soft tissue tumour, it can also present with a more aggressive local behavior, including locoregional recurrence or metastasis. In that case, a multidisciplinary approach is required for accurate diagnosis and proper management.


2021 ◽  
Author(s):  
Divyesh Kumar

World over life was going at its normal pace when an outbreak occurred in Hubei province of China in the later part of the year 2019. This outbreak was soon found to be caused by a virus named coronavirus (COVID-19). Rapidly the virus spread globally leading to a pandemic. The mortality rate was increasing day by day and helplessly everyone was wondering what actually could be done to prevent the spread. Lessons from the past epidemic made it possible to think that maintaining social distancing and adequate hygiene might help to combat the ailment. In India, majorly affected were the people from poor strata and the businessmen who were earning their daily bread by selling things of daily need. The health sector too witnessed an alarming ratio of patients suffering from COVID-19. The second wave, which soon followd the first wave, caused much more havoc. Overall, the COVID-19 pandemic, exposed and challanged the health security system of every country. As the danger of pandemic still prevails, steps to curtail the spread of disease and future management strategies should be formulated from the lessons learnt through the COVID-19 phase.


2021 ◽  
Vol 8 (1) ◽  
pp. 1-22
Author(s):  
George D. Malaperdas

Visibility (or Viewshed) Analysis in archeology is a function given through GIS, in purpose to contribute in the field of archaeology and especially in landscape archeology, by reconstituting the visual panorama of a study area of the past.  The concept of landscape archeology is a multidimensional research process that is not limited to archaeologists but places a special emphasis on a multidisciplinary approach. Mycenaean Messenia was the area of study and analysis of the visual panorama for two important reasons. First of all, it is a large area, which presents territories of varying heterogeneity in terms of morphology, while having a large sea front and an open observation horizon. Secondly, it is one of the continental regions of the Mycenaean period, which has evoked the largest number of residential facilities, structures and tombs, and also has been extensively studied by archaeologists since the 1920s. The main aim of this paper is to make an effort to identify archaeological information, through the bibliographic references of the archaeologists who studied the area, with the GIS visibility analysis. For that reason, the author tries for those residential locations that have been assigned a role or function of the site by archaeologists, such as an observation station, to be controlled in parallel and on the basis of new technologies (GIS and Viewshed Analysis) if this view is verified.


2015 ◽  
Vol 32 ◽  
pp. 53-58 ◽  
Author(s):  
Lorenzo Gitto ◽  
Luigi Bonaccorso ◽  
Aniello Maiese ◽  
Massimiliano dell'Aquila ◽  
Vincenzo Arena ◽  
...  

2021 ◽  
pp. 053331642110125
Author(s):  
Andrei Novac ◽  
Christine Zahn ◽  
Barton J. Blinder

Major social political changes over the past decades have stimulated an interest in both individual (i.e., personal) and group narratives as they relate to the decision-making process. In previous contributions, we have proposed the term Identity Narrative (IdN) to define a cognitive and emotional framework that serves as an implicit (unconscious) scaffold of human autobiography. IdN is a form of implicit memory, the acquisition of which begins with the first human nonverbal interactions. It serves as a framework for a person’s identity and creates relative stability and constancy for conscious, explicit, autobiographical memory. In this contribution we are presenting a multi-system exploration of the relationship between personal narratives as influenced by IdN and group narratives and their impact on social stability. We are presenting multi-disciplinary data from a variety of fields, including group psychoanalysis, memory research, the neuroscience of error prediction and free energy, and social science. We propose that in order to maintain social stability, the ratio between the entropy of personal narratives and group narratives in society also remains relatively stable. Based on the literature on group analysis, we are proposing a further investigation of the interchange between group narratives (group psychology, history, the humanities, culture in a society) and individual narratives (autobiography and IdN), and their impact at a societal level. By doing so, we are reiterating that the study of group analysis is of special socio-political significance in these historical times.


2005 ◽  
Vol 3 (4) ◽  
pp. 492 ◽  

In 2005, an estimated 40,340 new cases of rectal cancer will occur in the U.S., and experts estimate that during the same year, 56,290 people will die of rectal and colon cancer. As with colon cancer, however, mortality from rectal cancer has also decreased over the past 30 years. The NCCN Rectal Cancer Panel believes a multidisciplinary approach is necessary for effectively managing rectal cancer, an approach detailed here. For the most recent version of the guidelines, please visit NCCN.org


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Tejas Sheth ◽  
C. S. Pitchumoni ◽  
Kiron M. Das

Musculoskeletal manifestations are the most common extraintestinal manifestations in inflammatory bowel diseases. Some appendicular manifestations are independent of gut inflammation and are treated with standard anti-inflammatory strategies. On the other hand, axial involvement is linked to gut inflammatory activity; hence, there is a considerable amount of treatment overlap. Biological therapies have revolutionized management of inflammatory bowel diseases as well as of associated articular manifestations. Newer mechanisms driving gut associated arthropathy have surfaced in the past decade and have enhanced our interests in novel treatment targets. Introduction of biosimilar molecules is expected in the US market in the near future and will provide an opportunity for considerable cost savings on healthcare. A multidisciplinary approach involving a gastroenterologist, rheumatologist, and physical therapist is ideal for these patients.


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