scholarly journals Advances in Optical Adjunctive Aids for Visualisation and Detection of Oral Malignant and Potentially Malignant Lesions

2013 ◽  
Vol 2013 ◽  
pp. 1-17 ◽  
Author(s):  
Nirav Bhatia ◽  
Yastira Lalla ◽  
An N. Vu ◽  
Camile S. Farah

Traditional methods of screening for oral potentially malignant disorders and oral malignancies involve a conventional oral examination with digital palpation. Evidence indicates that conventional examination is a poor discriminator of oral mucosal lesions. A number of optical aids have been developed to assist the clinician to detect oral mucosal abnormalities and to differentiate benign lesions from sinister pathology. This paper discusses advances in optical technologies designed for the detection of oral mucosal abnormalities. The literature regarding such devices, VELscope and Identafi, is critically analysed, and the novel use of Narrow Band Imaging within the oral cavity is also discussed. Optical aids are effective in assisting with the detection of oral mucosal abnormalities; however, further research is required to evaluate the usefulness of these devices in differentiating benign lesions from potentially malignant and malignant lesions.

2016 ◽  
Vol 3 (57) ◽  
pp. 2988-2991
Author(s):  
Laveena P Mehta ◽  
Yessukrishna Prabhakar Shetty ◽  
Sharad B Bhalekar ◽  
Yogesh G Dabholkar ◽  
Haritosh K Velankar

2020 ◽  
Vol 6 (3) ◽  
pp. 70-73
Author(s):  
Nazila Esmaeili ◽  
Alfredo Illanes ◽  
Axel Boese ◽  
Nikolaos Davaris ◽  
Christoph Arens ◽  
...  

AbstractLongitudinal and perpendicular changes in the blood vessels of the vocal fold have been related to the advancement from benign to malignant laryngeal cancer stages. The combination of Contact Endoscopy (CE) and Narrow Band Imaging (NBI) provides intraoperative realtime visualization of vascular pattern in Larynx. The evaluation of these vascular patterns in CE+NBI images is a subjective process leading to differentiation difficulty and subjectivity between benign and malignant lesions. The main objective of this work is to compare multi-observer classification versus automatic classification of laryngeal lesions. Six clinicians visually classified CE+NBI images into benign and malignant lesions. For the automatic classification of CE+NBI images, we used an algorithm based on characterizing the level of the vessel’s disorder. The results of the manual classification showed that there is no objective interpretation, leading to difficulties to visually distinguish between benign and malignant lesions. The results of the automatic classification of CE+NBI images on the other hand showed the capability of the algorithm to solve these issues. Based on the observed results we believe that, the automatic approach could be a valuable tool to assist clinicians to classifying laryngeal lesions.


2020 ◽  
Author(s):  
Xianying He ◽  
Linlin Wang ◽  
Li Wang ◽  
Jinghong Gao ◽  
Fangfang Cui ◽  
...  

BACKGROUND Telepathology is a potent strategy to overcome the shortage of senior pathologists, whole slid imaging (WSI) is the most advanced means and has been widely used in telepathology owning to its complete scanning of glass slides, but WSI occupies large storage space and computing resource, and the WSI retrieval is time-consuming. To compensate for these shortcomings of WSI, we have established a cloud-based telepathology system and conducted detailed evaluation of its implementation effects. OBJECTIVE The cloud-based telepathology system in China has been running for more than four years, and a large number of cases were submitted. The main purpose of this study is to evaluate the operation effect of this system based on a large sample, including the overview of the submitted cases, timeliness of telepathology reports, diagnostic accuracy, and economic benefits. METHODS A total of 23,167 cases submitted to the cloud-based telepathology system of the National Telemedicine Center of China from January 2016 to December 2019 were collected as subjects. The variation tendency of the report-timeliness from the system were analyzed for years. 564 patients who also directly visited the First Affiliated Hospital of Zhengzhou University and obtained final diagnoses were followed up to analyze the diagnostic accuracy of the system. RESULTS The amounts of participated hospitals and submitted cases rose year by year. Most samples were captured from uterus, gastrointestinal tract, bone or soft tissue, breast, and esophagus. 17,495 cases were confirmed, including 12,088 benign lesions, 5217 malignant lesions, and 190 borderline lesions, the proportion of malignant lesions in esophagus, lung/mediastinum, urinary and thoracic cavity/pleura was higher than that in benign lesions, which was different from other 22 anatomic sites. The median turnaround time was 16.93 hours and shortened yearly (between 2018 and 2019 adjusted P= .012, other groups adjusted P< .001), 82.88% cases were diagnosed in 48 hours. The telepathological diagnosis of 11 cases were discrepant with the final diagnosis, and the diagnostic accuracy of the system was 98.05%, with no statistical difference from the final diagnosis in hospital(P= .549). 300,000 dollars were saved for patients every year with this system. CONCLUSIONS The novel cloud-based telepathology system has the potential to relieve the shortage of pathologists in primary hospitals and simultaneously reduced the high medical costs for patients in China. It should be therefore promoted further to enhance the efficiency, quantity and quality of telepathological diagnoses.


2020 ◽  
pp. 014556132092532 ◽  
Author(s):  
Chuanyao Lin ◽  
Sisi Zhang ◽  
Ling Lu ◽  
Maohua Wang ◽  
Xiaoyun Qian

Objectives: To explore the diagnostic value and pathological correlation of narrow band imaging (NBI) classification in laryngeal lesions. Methods: A total of 112 patients (123 lesions) with laryngeal lesions from July 2018 to May 2019 were selected in this study. All patients were examined by NBI and white light imaging endoscopy. The NBI endoscopy was applied to classify the observed lesion sites according to intraepithelial papillary capillary loop pattern. The gold standard of diagnosis was pathological results. To evaluate the consistency of NBI classification and pathological results. Results: The sensitivity, specificity, positive predictive value, and negative predictive value of the diagnosis for benign, precancerous, and malignant lesions under the NBI endoscopy were 90.91%, 81.19%, 74.07%, 85.42%; 41.67%, 92.93%, 58.82%, 86.79%; and 93.51%, 65.22%, 91.14%, 68.18%, respectively. There was a high consistency between NBI classification and pathological results (κ = 0.679, P < .001). Conclusions: The NBI classification can improve the accuracy of the diagnosis of laryngeal lesions. It is important for early diagnosis and treatment of vocal cord leukoplakia and laryngeal cancer.


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