scholarly journals Stress Evaluation in Adult Patients with Atopic Dermatitis Using Salivary Cortisol

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Megumi Mizawa ◽  
Masaki Yamaguchi ◽  
Chieko Ueda ◽  
Teruhiko Makino ◽  
Tadamichi Shimizu
Keyword(s):  
Atopic Dermatitis ◽  
Psychological Stress ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Serum Levels ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Saliva Cortisol ◽  
Salivary Cortisol Level

The symptoms of atopic dermatitis (AD) are often aggravated by stress, and AD can also lead to psychological stress due to social isolation and discrimination. The salivary cortisol level reflects psychological stress, and it is a good index to assess chronic stress. In this study, we measured the salivary cortisol levels in patients with AD (). AD patients were also evaluated for general disease severity using the Scoring Atopic Dermatitis (SCORAD) index. The serum levels of TARC, total IgE, and lactate dehydrogenase (LDH) and peripheral blood eosinophil counts were measured by laboratory tests. The Skindex-16 was used as a skin disease-specific, quality of life measure, instrument. The results showed that the saliva cortisol level was significantly higher in AD patients compared to healthy subjects () while the serum TARC and LDH levels were positively correlated with the SCORAD index. However, no statistically significant correlations were observed between the salivary cortisol level and Skindex-16. These results suggest that the saliva cortisol level is therefore a useful biomarker to evaluate the stress in AD patients.

Atopische Dermatitis: Die Frage nach dem Einfluss von Vitaminen bleibt weiter offen

2020 ◽  
Vol 8 (1) ◽  
pp. 19-20
Author(s):  
Regina Fölster-Holst
Keyword(s):  
Atopic Dermatitis ◽  
Peripheral Blood ◽  
High Performance ◽  
Atopische Dermatitis ◽  
Serum Levels ◽  
Blood Eosinophil ◽  
Normal Children ◽  
Study Objective ◽  
Peripheral Blood Eosinophil ◽  
Eosinophil Counts

Background: Several studies have suggested that vitamin D (VD) deficiency (VDD) is associated with atopic dermatitis (AD). However, little is known about the relationship between AD and vitamin A (VA). The interaction between VA and VD on AD requires further study. Objective: We detected serum levels of VA and VD in children with AD to explore how VA deficiency (VAD) and VDD affect AD severity. Methods: We assessed the SCORing Atopic Dermatitis (SCORAD) index, total immunoglobin E levels and peripheral blood eosinophil counts. VA and VD levels were determined with high-performance liquid chromatography. Correlations among variables were investigated with Pearson's correlation analysis. Results: The VD and VA levels were significantly lower in children with AD than in normal children (p < 0.001, p = 0.0423). Both VD and VA levels were negatively correlated with SCORAD scores. The SCORAD scores were significantly higher in AD patients with both VDD and VAD (co-deficiency) than in other AD patients. Significant inverse correlations were observed between peripheral blood eosinophil counts and serum VA and VD levels. Conclusions: VA and VD co-deficiency may exacerbate AD symptoms in children, but the specific mechanism underlying this relationship requires further study. These findings may indicate the need for studies evaluating the use of VD and VA as potential treatments for AD patients.

Effects of Relaxing Music on Salivary Cortisol Level after Psychological Stress

2003 ◽  
Vol 999 (1) ◽  
pp. 374-376 ◽  
Author(s):  
STÉPHANIE KHALFA ◽  
SIMONE DALLA BELLA ◽  
MATHIEU ROY ◽  
ISABELLE PERETZ ◽  
SONIA J. LUPIEN
Keyword(s):  
Psychological Stress ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Salivary Cortisol Level

Effects of Physical Workload on Salivary Cortisol Level

2004 ◽  
Vol 16 (1) ◽  
pp. 57 ◽  
Author(s):  
Dong Mug Kang ◽  
Byung Min Son ◽  
Sang Baek Koh ◽  
Junho Jang ◽  
Mia Son ◽  
...  
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Physical Workload ◽  
Salivary Cortisol Level

593 SALIVARY CORTISOL LEVEL IN PATIENTS WITH BURNING MOUTH SYNDROME

2009 ◽  
Vol 13 (S1) ◽  
Author(s):  
I. Glazar ◽  
H. Simic ◽  
I. Brekalo Prso ◽  
G. Brumini ◽  
S. Pezelj‐Ribaric
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Burning Mouth Syndrome ◽  
Salivary Cortisol Level ◽  
Burning Mouth

The effect of citrus ginger aroma on heart rate and salivary cortisol level during sleep at home

2018 ◽  
Vol 14 (4) ◽  
pp. 623-629
Author(s):  
Fang Jiang ◽  
Takemi Kobayashi ◽  
Takurou Ichihashi ◽  
Kanetoshi Ito ◽  
Shusaku Nomura
Keyword(s):  
Heart Rate ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Salivary Cortisol Level ◽  
At Home

scholarly journals Propensity-score-matched Evaluation of Psychological Stress and Hair Cortisol among People Living with HIV in China

2020 ◽  
Author(s):  
Xu Chen ◽  
Cheng-Bo Zeng ◽  
Shuai-Feng Liu ◽  
Xiao-Ming Li ◽  
Shan Qiao ◽  
...  
Keyword(s):  
Propensity Score ◽  
Psychological Stress ◽  
Perceived Stress ◽  
Cortisol Level ◽  
Stress Level ◽  
People Living With Hiv ◽  
Hair Cortisol ◽  
Mental Resilience ◽  
Living With Hiv

Abstract To compare the psychological stress level and hair cortisol level of people living with HIV (PLWH) with those without HIV. A total of 220 subjects were initially enrolled in the study, including 20 subjects living without HIV and 200 PLWH. Psychological stress level, including quality of life, anxiety, perceived stress and mental resilience, was self-reported in both groups with related scales. The cortisol in hair were extracted and assessed by LC-APCI-MS/MS method. Propensity score matching analysis was performed to balance the baseline covariates of the two groups, whereas the difference in psychological stress level and hair cortisol level between the two groups were compared. Furthermore, the associations between psychological stress level and cortisol level were examined. Two comparison groups were matched by 1:3 propensity score matching, which yield 20 subjects living without HIV and 60 PLWH. Ultimately, in regarding to the psychological stress, the levels of the anxiety, perceived stress and mental resilience were higher among PLWH than those living without HIV, but the people without HIV showed higher quality of life. The hair cortisol level in PLWH was higher than those living without HIV. However, there were no significant associations between psychological stress level and cortisol level. The PLWH showed higher level of psychological stress and cortisol than those without HIV. No relationship was seen between psychological stress level and cortisol level in PLWH.

scholarly journals The effect of supplementation of Lactobacillus paracasei HII01 on salivary cortisol, and dehydroepiandrosterone sulfate (DHEA-S) levels

2020 ◽  
Vol 11 (1) ◽  
pp. 12-15
Author(s):  
Ekasit Lalitsuradej ◽  
Bhagavathi Sundaram Sivamaruthi ◽  
Sasithorn Sirilun ◽  
Phakkharawat Sittiprapaporn ◽  
Sartjin Peerajan ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Dehydroepiandrosterone Sulfate ◽  
Chronic Fatigue ◽  
Lactobacillus Paracasei ◽  
Psychological State ◽  
Salivary Cortisol Level ◽  
Probiotic Intervention ◽  
Lactobacillus Paracasei Hii01

Background of the study: Fatigue is one of the serious health issues, and stress is the main factor that induces chronic fatigue syndrome (CFS). The dysregulation of stress management pathway may account for the development of CFS. The human body comprises several neurobiological networks to manage physical and emotional insults. Hypothalamic-pituitary- adrenal (HPA) axis is one of the important neuroendocrine networks involved in the neurophysiological activity of the host system. The response of HPA axis depends on the physical and psychological state of stress and other factors like time and duration of stress. The probiotic supplements are proved as an adjuvant therapeutic agent for several diseases.   Aims and Objective: The aim of the current study was to evaluate the effect of Lactobacillus paracasei HII01 supplementation on salivary cortisol and DHEA-S levels of fatigue subjects.   Materials and Methods: After 12-weeks of probiotic intervention significantly reduced the salivary cortisol level, while DHEA-S level was not affected. The ratio of cortisol: DHEA-S was reduced after probiotic intervention.   Results: The results concluded that L. paracasei HII01 has the ability to reduce the stress level in fatigue subjects by reducing the salivary cortisol level. Conclusion: The results evidently to recommend that the ingestion of 12.5 billion cells of L. paracasei HII01 per day for 12 weeks significantly amended HPA-Axis by lowering salivary cortisol and ratio cortisol: DHEA-S in fatigue subjects.

scholarly journals Multifaceted Analyses of Epidermal Serine Protease Activity in Patients with Atopic Dermatitis

2020 ◽  
Vol 21 (3) ◽  
pp. 913 ◽  
Author(s):  
Hayato Nomura ◽  
Mutsumi Suganuma ◽  
Takuya Takeichi ◽  
Michihiro Kono ◽  
Yuki Isokane ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Serine Protease ◽  
Protease Activity ◽  
Serine Proteases ◽  
Immunoglobulin E ◽  
Total Serum ◽  
Tape Stripping ◽  
Blood Eosinophil ◽  
Peripheral Blood Eosinophil ◽  
Serine Protease Activity

The serine proteases kallikrein-related peptidase (KLK) 5 and KLK7 cleave cell adhesion molecules in the epidermis. Aberrant epidermal serine protease activity is thought to play an important role in the pathogenesis of atopic dermatitis (AD). We collected the stratum corneum (SC) from healthy individuals (n = 46) and AD patients (n = 63) by tape stripping and then measuring the trypsin- and chymotrypsin-like serine protease activity. We also analyzed the p.D386N and p.E420K of SPINK5 variants and loss-of-function mutations of FLG in the AD patients. The serine protease activity in the SC was increased not only in AD lesions but also in non-lesions of AD patients. We found, generally, that there was a positive correlation between the serine protease activity in the SC and the total serum immunoglobulin E (IgE) levels, serum thymus and activation-regulated chemokine (TARC) levels, and peripheral blood eosinophil counts. Moreover, the p.D386N or p.E420K in SPINK5 and FLG mutations were not significantly associated with the SC’s serine protease activity. Epidermal serine protease activity was increased even in non-lesions of AD patients. Such activity was found to correlate with a number of biomarkers of AD. Further investigations of serine proteases might provide new treatments and prophylaxis for AD.

Impulsivity and Salivary Cortisol Level in Patients With Substance Dependence

2019 ◽  
Vol 18 (1) ◽  
pp. 1-9
Author(s):  
Hani H. Dessoki ◽  
Osama Refaat ◽  
Hisham Salah ◽  
Taghrid Tahoun ◽  
Maha Emadeldin ◽  
...  
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Substance Dependence ◽  
Salivary Cortisol Level
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