scholarly journals Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Dhara Chaudhari ◽  
Conchitina Crisostomo ◽  
Charles Ganote ◽  
George Youngberg
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Weight Reduction ◽  
Rare Complication ◽  
Case Review ◽  
Review Of The Literature ◽  
Over The Counter ◽  
Oxalate Absorption ◽  
Intravenous Hydration ◽  
Oxalate Nephropathy

Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal failure which improved minimal with intravenous hydration. She was found to have oxalate crystals on renal biopsy. Patient admitted orlistat use over the counter for weight reduction on further questioning. The purpose of this case review is to increase awareness among patients since they are more focused on losing weight. This case also calls for the provider attention to educate patients regarding side effects of orlistat because of easy availability of orlistat over the counter.

scholarly journals Acute renal failure due to acetaminophen ingestion: a case report and review of the literature.

1995 ◽  
Vol 6 (1) ◽  
pp. 48-53
Author(s):  
P Blakely ◽  
B R McDonald
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Hepatic Dysfunction ◽  
The United States ◽  
Hepatic Necrosis ◽  
Review Of The Literature ◽  
Over The Counter ◽  
Tubular Necrosis ◽  
Drug History ◽  
Margin Of Safety

Acetaminophen is the most commonly reported drug overdose in the United States. Acute renal failure occurs in less than 2% of all acetaminophen poisonings and 10% of severely poisoned patients. At the therapeutic dosages, acetaminophen can be toxic to the kidneys in patients who are glutathione depleted (chronic alcohol ingestion, starvation, or fasting) or who take drugs that stimulate the P-450 microsomal oxidase enzymes (anticonvulsants). Acute renal failure due to acetaminophen manifests as acute tubular necrosis (ATN). ATN can occur alone or in combination with hepatic necrosis. The azotemia of acetaminophen toxicity is typically reversible, although it may worsen over 7 to 10 days before the recovery of renal function occurs. In severe overdoses, renal failure coincides with hepatic encephalopathy and dialysis may be required. Recognition of acetaminophen nephropathy requires the following: (1) a thorough drug history, including over-the-counter medications such as Tylenol or Nyquil; (2) knowledge of the risk factors that lessen its margin of safety at therapeutic ingestions, i.e., alcoholism; and (3) consideration of acetaminophen in the differential diagnosis of patients who present with combined hepatic dysfunction and ATN.

Acute Renal Failure Caused by Imiquimod 5% Cream in a Renal Transplant Patient: Review of the Literature on Side Effects of Imiquimod

Dermatology ◽  
2011 ◽  
Vol 222 (2) ◽  
pp. 109-112 ◽  
Author(s):  
J. Santos-Juanes ◽  
A. Esteve ◽  
A. Mas-Vidal ◽  
P. Coto-Segura ◽  
E. Salgueiro ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Side Effects ◽  
Renal Transplant ◽  
Renal Transplant Patient ◽  
Transplant Patient ◽  
Review Of The Literature

scholarly journals Low-Dose Aminophylline for the Treatment of Neonatal Non-Oliguric Renal Failure—Case Series and Review of the Literature

2008 ◽  
Vol 13 (2) ◽  
pp. 80-87
Author(s):  
Bethany A. Lynch ◽  
Peter Gal ◽  
J. Laurence Ransom ◽  
Rita Q. Carlos ◽  
Mary Ann V.T. Dimaguila ◽  
...  
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Chart Review ◽  
Low Dose ◽  
Case Series ◽  
Retrospective Chart Review ◽  
Review Of The Literature ◽  
Oliguric Renal Failure ◽  
The Impact

OBJECTIVE Aminophylline is a methylxanthine with multiple physiologic actions. At low doses, aminophylline can antagonize adenosine and improve renal function via increased glomerular filtration rate. Despite its clinical use, little data exists in neonates for this indication. Therefore, the objective of this report is to describe the impact of aminophylline on renal function indices in a series of neonates with acute renal failure. MATERIALS AND METHODS This was a retrospective chart review of 13 neonates with acute renal failure who received aminophylline during a 15-month study period. Aminophylline was administered at 1 mg/kg intravenously or orally every twelve hours. Forty-six percent (n = 6) of the patients received a 5 mg/kg loading dose before initiation of maintenance therapy. Most patients had already received other treatments for renal failure, including diuretics and dopamine. RESULTS Resolution of acute renal failure (with normalization of serum creatinine and blood urea nitrogen) was documented in 10 patients (77%). Four of the thirteen patients died from complications due to their prematurity. Failure of low-dose aminophylline was observed in 3 of the 4 patients who died. CONCLUSIONS Low-dose aminophylline in neonates with acute renal failure is associated with an improvement in renal function indices.

scholarly journals Development of the proteinuria dosage

2021 ◽  
Vol 14 (3) ◽  
pp. 079-081
Author(s):  
Andriamiarimbola Irène Rakotoniaina ◽  
Miora Koloina Ranaivosoa ◽  
Annick Anjatiana Raherinaivo ◽  
Andry Rasamindrakotroka
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Kidney Disease ◽  
Urine Sample ◽  
Protein Detection ◽  
Urine Collection ◽  
Creatinine Ratio ◽  
Review Of The Literature ◽  
Creatinine Excretion ◽  
Albumin Creatinine Ratio

The 24-hour urine proteinuria or albuminuria ratio is still prescribed for protein detection in urine, despite the fact that it has been replaced by the albuminuria or protein/creatininuria ratio. The use of this ratio eliminates the misinterpretation of 24-hour urine proteinuria. The objective of this development is to clarify the importance of the ratio for the search for albumin or protein in the urine. We conducted a review of the literature focusing on different diagnostic recommendations. Indeed, 24-hour urine collection is tedious and prone to many errors. The ratio is therefore a simple, reliable and standardized indicator for assessing proteinuria except in acute renal failure patients. The correlation between these ratios and 24-hour urine has been demonstrated in several studies in various populations and is currently considered to be the most adequate measure for proteinuria quantification despite the variability in creatinine excretion. The Kidney Disease Improving Global Outcomes recommendations therefore suggest the use of the albumin/creatinine ratio and the protein/creatinine ratio on a 1st morning urine sample to test for proteinuria.

Bee sting leading to stroke: a case report and review of the literature

2021 ◽  
Vol 14 (11) ◽  
pp. e240693
Author(s):  
Shivakumar K Masaraddi ◽  
Rohan J Desai ◽  
Swanit Hemant Deshpande ◽  
Sameet Patel
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Diffusion Mri ◽  
Left Middle Cerebral Artery ◽  
Acute Pulmonary Oedema ◽  
Middle Cerebral Artery Territory ◽  
Review Of The Literature ◽  
Bee Sting ◽  
Local Reactions ◽  
Left Middle

In India, bee stings are very common, seen mainly in farmers and honey collectors. Usually, it presents with local reactions and anaphylaxis. It rarely requires urgent hospitalisation. Other major complications seen are acute renal failure, intravascular coagulation, rhabdomyolysis and acute pulmonary oedema. Stroke as a presentation is uncommon. We report a case of a 45-year-old man presenting with right-sided hemiplegia and aphasia due to multiple bee stings. Diffusion MRI showed left middle cerebral artery territory hyperacute infarct.

Thrombotic Microangiopathy in Cocaine Abuse–Associated Malignant Hypertension: Report of 2 Cases With Review of the Literature

2007 ◽  
Vol 131 (12) ◽  
pp. 1817-1820 ◽  
Author(s):  
Xin Gu ◽  
Guillermo A. Herrera
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Thrombotic Microangiopathy ◽  
Cocaine Abuse ◽  
Illicit Drugs ◽  
Malignant Hypertension ◽  
Fibrinoid Necrosis ◽  
Elevated Blood ◽  
Review Of The Literature ◽  
Accelerated Hypertension

Abstract Cocaine is one of the most commonly used illicit drugs. Acute renal failure is an emergent complication in patients with acute cocaine intoxication. It is well known that rhabdomyolysis and vasoconstriction can be important pathogenetic mechanisms resulting in acute renal failure in these patients. Clinically, although cocaine abuse is associated with elevated blood pressure, persistent accelerated hypertension reaching levels diagnostic of malignant hypertension is uncommon. Cocaine-induced malignant hypertension associated with morphologic features of thrombotic macroangiopathy has been rarely mentioned in the literature. We report 2 cases of cocaine abuse–associated malignant hypertension with renal failure. Kidney biopsies revealed thrombotic microangiopathy with fibrinoid necrosis of arterioles and glomerular tufts. Cocaine-mediated endothelial injury and platelet activation may play important pathogenetic roles in cocaine abusers who develop acute renal failure and malignant hypertension.

RAPIDLY PROGRESSIVE T CELL LYMPHOMA PRESENTING AS ACUTE RENAL FAILURE: Case Report and Review of the Literature

1997 ◽  
Vol 17 (3) ◽  
pp. 449-460 ◽  
Author(s):  
Thomas S. Neuhauser ◽  
Kristen Lancaster ◽  
Robert Haws ◽  
Dennis Drehner ◽  
Margaret L. Gulley ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Case Report ◽  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Review Of The Literature
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