scholarly journals Urgent Splenectomy after Partial Splenic Embolization in Liver-Transplanted Patient: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Jorge Herrador Benito ◽  
M. G. Zunzarren ◽  
T. Pozancos de Simón ◽  
L. Tortolero ◽  
R. Latorre Fragua ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Treatment ◽  
Splenic Abscess ◽  
Severe Complication ◽  
Partial Splenic Embolization ◽  
Transplant Patients ◽  
Splenic Embolization

We describe a 51-year-old-male. Three months after liver transplantation due to hepatitis C virus (HCV) hepatopathy, an HCV relapse was detected, and partial splenic embolization (PSE) was performed prior to antiviral treatment. Eleven days after PSE emergency splenectomy was performed due to the development of a splenic abscess, which is a rare but severe complication of PSE. Between May 2002 and March 2012, 18 PSEs have been performed in transplant patients in our centre. The patient presented here is the only case of splenic abscess and the only one who has needed surgery after complications of PSE.

scholarly journals Impact of Treatment against Hepatitis C Virus on Overall Survival of Naive Patients with Advanced Liver Disease

2014 ◽  
Vol 59 (2) ◽  
pp. 803-810 ◽  
Author(s):  
Blaise K. Kutala ◽  
Jeremie Guedj ◽  
Tarik Asselah ◽  
Nathalie Boyer ◽  
Feryel Mouri ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Beneficial Effect ◽  
Antiviral Treatment ◽  
Biochemical Response ◽  
Risk Of Death ◽  
Unsuccessful Treatment ◽  
Advanced Liver Fibrosis ◽  
Baseline Characteristics

ABSTRACTThe beneficial effect of achieving a sustained virological response (SVR) after antiviral treatment against hepatitis C virus is well established. However, it remains unclear whether unsuccessful treatment (non-SVR) also improves patient survival, especially in patients with advanced liver fibrosis. We retrospectively evaluated the incidence of death or liver transplantation in the 427 naive patients with a Child-Pugh score of A and advanced fibrosis newly admitted to the Hospital Beaujon between 2000 and 2010. Patients were followed for a median time of 5.5 years. The baseline characteristics of untreated (n= 102) and treated (n= 325) patients were largely similar, and there was no evidence of a bias of indication. Treated patients received a combination of interferon and ribavirin and had an SVR rate of 32%. The incidence of death or liver transplantation per 100 person-years was 1.00, 3.20, and 5.44 in SVR, non-SVR, and untreated patients, respectively. After adjusting for baseline characteristics, the risk of death or liver transplantation was significantly lower in SVR than in non-SVR patients and in non-SVR than in untreated patients (hazard ratios, 0.35 and 0.51, respectively;P= 0.019 and 0.038, respectively). The effect of treatment in non-SVR patients was higher in patients who had a virological or a biochemical response than in those who did not have a virological or a biochemical response. The risk of death or liver transplantation was significantly lower in treated than in untreated patients. Moreover, there was a gradient of mortality between patients with SVRs, virological or biochemical responders, and untreated patients, suggesting that treatment, even in the absence of viral eradication, has a beneficial effect on survival.

Impact of hepatitis C virus (HCV) antiviral treatment on the need for liver transplantation (LT)

2017 ◽  
Vol 38 (6) ◽  
pp. 1022-1027 ◽  
Author(s):  
Esteban Sáez-González ◽  
Carmen Vinaixa ◽  
Fernando San Juan ◽  
Vanesa Hontangas ◽  
Salvador Benlloch ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Treatment

Partial Splenic Embolization for the Treatment of Hypersplenism in Liver Transplanted Patients with Hepatitis C Virus Recurrence before peg-Interferon Plus Ribavirin

2005 ◽  
Vol 79 (11) ◽  
pp. 1634-1635 ◽  
Author(s):  
Rafael B??rcena ◽  
Luis Gil-Grande ◽  
Javier Moreno ◽  
Jos?? R. Foruny ◽  
Elena Ot??n ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Partial Splenic Embolization ◽  
Splenic Embolization
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