scholarly journals Correlation between US-PSV and 64-Row MDCTA with Advanced Vessel Analysis in the Quantification of 50–70% Carotid Artery Stenosis

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Matteo Stefanini ◽  
Eleonora Gaspari ◽  
Luca Boi ◽  
Costantino Del Giudice ◽  
Roberta Mastrangeli ◽  
...  

Purpose. To correlate ultrasonographic peak systolic velocity (US-PSV) and 64-row multidetector computed tomography angiography (MDCTA) with advanced vessel analysis (AVA) software in the quantification of 50–70% carotid artery stenosis.Materials and methods. 199 consecutive patients (247 arteries) with internal carotid artery (ICA) or third proximal bifurcation stenosis. Each patient was studied by duplex US (DUS) and 64-row MDCTA with AVA software.Results. DUS showed PSV measurements less than 125 cm/s in 51 carotid stenosis and a value greater than this in 196 arteries. 64-row MDCTA AVA software showed a grade of stenosis less than 50% in 42 carotid arteries while a greater 70% was found in 4 carotid arteries; then, carotid arteries with stenosis percentage between 50% and 70% were 201. Linear regression analysis showed a good linear correlation () between MDCTA-AVA software percentage stenosis and PSV: between 50% grade of stenosis and PSV value corresponding to 133,6 cm/sec and between 70% stenosis and PSV value corresponding to 268 cm/sec. The sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) of this analysis were 93%, 82%, 97%, 75%, respectively.Conclusion. Linear correlation between PSV data and grade of stenosis from 50% to 70% obtained with 64-row MDCTA AVA software. Main PSV value corresponding to 50% and 70% grade of stenosis at AVA analysis.

2018 ◽  
Vol 42 (4) ◽  
pp. 155-161
Author(s):  
Jing Xu ◽  
Samuel S. Rafla ◽  
Michelle K. Pouria ◽  
Drena Root ◽  
Shannon H. Lyons ◽  
...  

External carotid artery (ECA) disease has been understated in the current literature, likely secondary to the lack of clinical neurological symptoms when this vessel is stenotic. However, vascular ultrasound credentialing entities request the adoption of specific criteria for the assessment of the ECA. Our purpose is to determine the ultrasound criteria for the detection of hemodynamically significant stenosis (50%-99%) using computed tomography angiography (CTA) as the reference standard. We included patients who had a carotid ultrasound and a CTA of the neck performed both within a 12-month period. Ultrasound measurements were reviewed for technical accuracy. CTAs were reassessed to determine the degree of stenosis of the bilateral ECAs adopting the North American Symptomatic Carotid Endarterectomy Trial criteria. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated for different peak systolic velocity (PSV) cutoff points to determine the most accurate PSV for detecting 50% to 99% stenosis of the ECA. Receiver operating curve analysis was used to assess diagnostic performance. Of the 536 ECAs included in this study, 13 were noted to be occluded by CTA. Six of these occlusions were accurately detected by ultrasound. There were 82 ECAs with 50% to 99% stenosis on CTA; these vessels had a significantly higher mean PSV compared to ECAs with <50% stenosis (294 vs 122 cm/s) ( P < .0001). A cutoff velocity of ⩾200 cm/s demonstrated a sensitivity, specificity, and overall accuracy of 0.84, 0.93, and 0.91, respectively. Using univariate analysis, smoking was significantly associated with the presence of ⩾50% ECA stenosis. We determined that a PSV cutoff of ⩾200 cm/s showed high sensitivity and specificity for detecting 50% to 99% ECA stenosis based on CTA.


2014 ◽  
Vol 47 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Vilson Lacerda Brasileiro Junior ◽  
Aníbal Henrique Barbosa Luna ◽  
Marcelo Augusto Oliveira de Sales ◽  
Tânia Lemos Coelho Rodrigues ◽  
Priscilla Lopes da Fonseca Abrantes Sarmento ◽  
...  

Objective The present study evaluated the reliability of digital panoramic radiography in the diagnosis of carotid artery calcifications. Materials and Methods Thirty-five patients under high-risk for development of carotid artery calcifications who had digital panoramic radiography were referred to undergo ultrasonography. Thus, 70 arteries were assessed by both methods. The main parameters utilized to evaluate the panoramic radiography reliability in the diagnosis of carotid artery calcifications were accuracy, sensitivity, specificity and positive predictive value of this method as compared with ultrasonography. Additionally, the McNemar's test was utilized to verify whether there was a statistically significant difference between digital panoramic radiography and ultrasonography. Results Ultrasonography demonstrated carotid artery calcifications in 17 (48.57%) patients. Such individuals presented with a total of 29 (41.43%) carotid arteries affected by calcification. Radiography was accurate in 71.43% (n = 50) of cases evaluated. The degree of sensitivity of this method was 37.93%, specificity of 95.12% and positive predictive value of 84.61%. A statistically significant difference (p < 0.001) was observed between the methods evaluated in their capacity to diagnose carotid artery calcifications. Conclusion Digital panoramic radiography should not be indicated as a method of choice in the investigation of carotid artery calcifications.


2021 ◽  
Vol 7 ◽  
Author(s):  
Sheng-Jiang Chen ◽  
Rui-Rui Liu ◽  
Yi-Ran Shang ◽  
Yu-Juan Xie ◽  
Xiao-Han Guo ◽  
...  

Purpose: The present study aimed to explore the predictive ability of an ultrasound linear regression equation in patients undergoing endovascular stent placement (ESP) to treat carotid artery stenosis-induced ischemic stroke.Methods: Pearson's correlation coefficient of actual improvement rate (IR) and 10 preoperative ultrasound indices in the carotid arteries of 64 patients who underwent ESP were retrospectively analyzed. A predictive ultrasound model for the fitted IR after ESP was established.Results: Of the 10 preoperative ultrasound indices, peak systolic velocity (PSV) at stenosis was strongly correlated with postoperative actual IR (r = 0.622; P &lt; 0.01). The unstable plaque index (UPI; r = 0.447), peak eccentricity ratio (r = 0.431), and plaque stiffness index (β; r = 0.512) moderately correlated with actual IR (P &lt; 0.01). Furthermore, the resistance index (r = 0.325) and the dilation coefficient (r = 0.311) weakly correlated with actual IR (P &lt; 0.05). There was no significant correlation between actual IR and the number of unstable plaques, area narrowing, pulsatility index, and compliance coefficient. In combination, morphological, hemodynamic, and physiological ultrasound indices can predict 62.39% of neurological deficits after ESP: fitted IR = 0.9816 – 0.1293β + 0.0504UPI – 0.1137PSV.Conclusion: Certain carotid ultrasound indices correlate with ESP outcomes. The multi-index predictive model can be used to evaluate the effects of ESP before surgery.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ivan Platzek ◽  
Dominik Sieron ◽  
Philipp Wiggermann ◽  
Michael Laniado

Purpose. The aim of this study was to assess the correlation of 3D time-of-flight MR angiography (TOF MRA) and contrast-enhanced MR angiography (CEMRA) for carotid artery stenosis evaluation at 3T.Material and Methods. Twenty-three patients (5 f, 18 m; mean age 61 y, age range 45–78 y) with internal carotid artery stenosis detected with ultrasonography were examined on a 3.0T MR system. The MR examination included both 3D TOF MRA and CEMRA of the carotid arteries. MR images were evaluated independently by two board-certified radiologists. Stenosis evaluation was based on a five-point scale. Stenosis grades determined by TOF and CEMRA were compared using Spearman’s rank correlation coefficient and the Wilcoxon test. Cohen’s Kappa was used to evaluate interrater reliability.Results. CEMRA detected stenosis in 24 (52%) of 46 carotids evaluated, while TOF detected stenosis in 27 (59%) of 46 carotids. TOF MRA yielded significantly higher results for stenosis grade in comparison to CEMRA (P=0.014). Interrater agreement was very good for both TOF MRA (κ=0.93) and CEMRA (κ=0.93).Conclusion. At 3T, 3D TOF MRA should not be used as replacement for contrast-enhanced MRA of the carotid arteries, as it results in significantly higher stenosis grades.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Masatomo Miura ◽  
Kiyofumi Yamada ◽  
Takuya Kanamaru ◽  
Kazutaka Uchida ◽  
Manabu Shirakawa ◽  
...  

Background: Vasa vasorum neovascularization (VVN) is one of the characteristics of vulnerable plaque. The purpose of this study was to assess VVN using optical frequency domain imaging (OFDI) between symptomatic and asymptomatic carotid artery plaques, and to know its association with progression of stenosis. Methods: The carotid artery plaques were examined before angioplasty using OFDI system (LUNAWAVE TM , Terumo). VVN was defined as a no-signal tubuloluminal structures recognized on at least 3 consecutive images. A total number of VVN was compared between symptomatic and asymptomatic plaques. The stenosis was evaluated by carotid duplex scan within one year. The lesion was diagnosed as ‘progressive’ when the stenotic degree and peak systolic velocity were increased. Results: A total of 60 patients (29 symptomatic, 11 progression) were included. VVN was detected in 54 patients (90%), the total number of VVN was significantly higher in progressive stenosis (8.9 ± 5.7 vs. 4.5 ± 3.8, p = 0.02). However, there was no relationship between the number of VVN and ischemic symptom. Conclusions: VVN was more frequently observed in progressive stenosis. Evaluation of VVN using OFDI might be useful to predict progression of carotid artery stenosis.


2012 ◽  
Vol 28 (2) ◽  
pp. 68-72
Author(s):  
Eun Mi Kong ◽  
Jang Yong Kim ◽  
Yong Sun Jeon ◽  
Soon Gu Cho ◽  
Kee Chun Hong

Sign in / Sign up

Export Citation Format

Share Document