scholarly journals A Novel Approach to Design Chitosan-Polyester Materials for Biomedical Applications

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Tatiana A. Akopova ◽  
Tatiana S. Demina ◽  
Alexander N. Shchegolikhin ◽  
Tikhon S. Kurkin ◽  
Christian Grandfils ◽  
...  
Keyword(s):  
Low Temperatures ◽  
Biomedical Applications ◽  
Oxidative Degradation ◽  
Shear Stresses ◽  
Chemical Transformations ◽  
Melting Points ◽  
Reactive Blending ◽  
Crystalline Polymers ◽  
Solid Polymers ◽  
Novel Approach

A novel approach to design chitosan-polyester materials is reported. The method is based on mechanical activation and effective intermixing of the substrates under high pressure and shear deformation in the course of solid-state reactive blending. The marked departure of this approach from previous practice resides on exploitation of a variety of chemical transformations of the solid polymers that become feasible under conditions of plastic flow. Low temperatures (aboveTgbut below the melting points of the crystalline polymers) are maintained throughout the process, minimizing mechanical and oxidative degradation of the polymers. Morphology as well as structural, mechanical, and relaxation properties of those prepared blends of chitosan with semicrystalline poly(L,L-lactide) and amorphous poly(D,L-lactide-co-glycolide) has been studied. Grafting of polyester moieties onto chitosan chains was found to occur under employed pressures and shear stresses. The prepared polymer blends have demonstrated an amphiphilic behavior with a propensity to disperse in organic solvents that widens possibilities to transform them into promising materials for various biomedical applications.

scholarly journals Novel Approach to Tooth Chemistry: Quantification of Human Enamel Apatite in Context for New Biomaterials and Nanomaterials Development

2020 ◽  
Vol 22 (1) ◽  
pp. 279
Author(s):  
Andrzej Kuczumow ◽  
Renata Chałas ◽  
Jakub Nowak ◽  
Wojciech Smułek ◽  
Maciej Jarzębski
Keyword(s):  
Biomedical Applications ◽  
Energy Levels ◽  
New Class ◽  
Novel Approach ◽  
Human Enamel ◽  
Linear Profiles ◽  
Resistant Form ◽  
Molar Teeth ◽  
Stable Core ◽  
Nanoscale Level

A series of linear profiles of the elements of the enamel in human molar teeth were made with the use of an electron microprobe and a Raman microscope. It is postulated that the enamel can be treated as the superposition of variable “overbuilt” enamel on the stable “core” enamel at the macro-, micro- and nanoscale level. The excessive values characterize the “overbuilt enamel”. All the profiles of excessive parameters along the enamel thickness from the enamel surface to the dentin enamel junction (DEJ) can be approximated very precisely with the use of exponential functions, where Ca, P, Cl and F spatial profiles are decaying while Mg, Na, K and CO32− ones are growing distributions. The “overbuilt” apatite formed on the boundary with DEJ, enriched in Na, Mg, OH and carbonates, reacts continuously with Ca, Cl and F, passing into an acid-resistant form of the “overbuilt” enamel. The apparent phases arriving in boundary regions of the “overbuilt enamel” were proposed. Microdiffraction measurements reveal relative variation of energy levels during enamel transformations. Our investigations are the milestones for a further new class of biomaterial and nanomaterial development for biomedical applications.

Single-molecule spectromicroscopy: a route towards sub-wavelength refractometry

2015 ◽  
Vol 184 ◽  
pp. 263-274 ◽  
Author(s):  
T. A. Anikushina ◽  
M. G. Gladush ◽  
A. A. Gorshelev ◽  
A. V. Naumov
Keyword(s):  
Refractive Index ◽  
Single Molecule ◽  
Low Temperatures ◽  
Radiative Lifetime ◽  
Spatially Resolved ◽  
Local Fluctuations ◽  
Novel Approach ◽  
Spectral Linewidth ◽  
Spatial Fluctuations ◽  
Sub Wavelength

We suggest a novel approach for spatially resolved probing of local fluctuations of the refractive index n in solids by means of single-molecule (SM) spectroscopy. It is based on the dependence T1(n) of the effective radiative lifetime T1 of dye centres in solids on n due to the local-field effects. Detection of SM zero-phonon lines at low temperatures gives the values of the SM natural spectral linewidth (which is inversely proportional to T1) and makes it possible to reveal the distribution of the local n values in solids. Here we demonstrate this possibility on the example of amorphous polyethylene and polycrystalline naphthalene doped with terrylene. In particular, we show that the obtained distributions of lifetime limited spectral linewidths of terrylene molecules embedded into these matrices are due to the spatial fluctuations of the refractive index local values.

Structural Performance of Pultruded Composites under Elevated Temperatures

2009 ◽  
Vol 79-82 ◽  
pp. 2223-2226
Author(s):  
Ayman S. Mosallam
Keyword(s):  
Elevated Temperature ◽  
High Temperatures ◽  
Elevated Temperatures ◽  
Oxidative Degradation ◽  
Viscoelastic Behavior ◽  
Structural Performance ◽  
Crystalline Polymers ◽  
Damage To The Material ◽  
Continuous Working ◽  
Pultruded Composites

One of the major limitations for wider use of pultruded fiber reinforced polymeric (PFRP) composites in the civil engineering sector has been their behavior under elevated temperature and ultimately fire. This limitation arises not only due to the reduction in mechanical properties at high temperatures, including increased propensity to creep, but also due to limitations on the continuous working temperature causing permanent damage to the material as a result of thermal and oxidative degradation. Significant gains in property retention at high temperatures with crystalline polymers have been derived from the incorporation of fibrous reinforcement, but the development of new polymer matrices is the key for further elevation of the useful temperature range. This paper presents summary results of a research project focused on characterizing the viscoelastic behavior of commercially-produced, off-the-shelf unidirectional PFRP materials subjected to elevated temperature environments.

scholarly journals A method for pet mechanical properties enhancement

2019 ◽  
Vol 10 (8) ◽  
pp. 1725
Author(s):  
Raffaella Aversa ◽  
Relly Victoria Virgil Petrescu ◽  
Antonio Apicella ◽  
Florian Ion Tiberiu Petrescu
Keyword(s):  
Mechanical Properties ◽  
Liquid Crystalline ◽  
Liquid Crystalline Polymers ◽  
Molecular Structures ◽  
Reactive Blending ◽  
Scanning Calorimetry ◽  
Shear Transfer ◽  
Crystalline Polymers ◽  
Reactive Compatibilizer

A method for PET mechanical properties enhancement by reactive blending with HBA/HNA Liquid Crystalline Polymers for in situ highly fibrillar composites preparation is presented. LCP/PET blends were reactively extruded in presence of Pyromellitic Di-Anhydride (PMDA) and then characterized by Differential Scanning Calorimetry, Thermally Stimulated Currents and tensile mechanical properties. Moderate amounts of LCP in the PET (0.5 and 5%) and small amounts of thermo-active and reactive compatibilizer in the blend (0.3%) were found to significantly improve LCP melt dispersion, melts shear transfer and LCP fibril formation and adhesion. An unexpected improvement was probably due to the presence of two distinct phases’ supra-molecular structures involving PET-LCP and PMDA.

scholarly journals Formulation and Evaluation of Copper Nanoparticles Loaded Microsponges

2019 ◽  
Vol 11 (04) ◽  
Author(s):  
S. Kothai ◽  
R. Umamaheswari
Keyword(s):  
Copper Nanoparticles ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Entrapment Efficiency ◽  
Diffusion Method ◽  
Hibiscus Rosa Sinensis ◽  
Novel Approach ◽  
Targeted Drug ◽  
Antimicrobial And Antioxidant Activity ◽  
Emulsion Solvent Diffusion Method

Microsponges become imperative in the field of targeted drug delivery and in other biomedical applications. There was a clamant need for designing microsponges incorporating with green synthesised metal nanoparticles rather than the chemical drug in order to reduce the side effects of the drug and thus increasing the effectiveness of nature of the whole material. It provokes us to design this novel approach of loading copper nanoparticles into the microsponges. Here in this work, microsponges based on ethyl cellulose and polyvinyl alcohol were synthesised by Quasi-Emulsion Solvent diffusion method in which copper nanoparticles procured from Hibiscus rosa-sinensis leaf extract was incorporated. The Loaded microsponges were characterised by High Resolution Scanning Electron Microscopy (HR-SEM) and Particle size distribution Analyzer (PSA). The Drug content and Entrapment Efficiency of the microsponges were found out. The antimicrobial and antioxidant activity of the loaded microsponges were evaluated.

Modeling the Torsional Cyclic Response of Direct Metal Laser Sintered Inconel 718

2019 ◽  
Author(s):  
Sanna F. Siddiqui ◽  
Firat Irmak ◽  
Nathan O’Nora ◽  
Ali P. Gordon
Keyword(s):  
Constitutive Modeling ◽  
Inconel 718 ◽  
Mechanical Test ◽  
Experimental Testing ◽  
Fatigue Tests ◽  
Multiaxial Fatigue ◽  
Shear Stresses ◽  
Cyclic Shear ◽  
Novel Approach ◽  
Gauge Section

Abstract The aerospace propulsion industry has seen strides in the use of the additive manufacturing (AM) technology in the rapid prototyping and geometric design flexibility of aerospace parts, with concurrent efforts on 3D printing turbine engine blades of Inconel 718 material [1] for use in aircraft engines. The tensile, compressive and axial fatigue response of AM Inconel 718, along with associated constitutive modeling of the material response exhibited under these mechanical test conditions have been reported. However, in addition to understanding the axial behavioral response exhibited by this material, assessing the role of cyclic shear stresses, through experimental testing and constitutive modeling can provide preliminary insight into the mechanical behavior of AM Inconel 718 under multiaxial loading conditions. This study has presented a novel approach to constitutively model the experimental cyclic shearing deformation of as-built direct metal laser sintered (DMLS) Inconel 718, manufactured along varying build orientations in the xy, yz and xz planes, compared with wrought annealed Inconel 718. Specimens were subjected to completely reversible torsional fatigue tests at room temperature, under angle of twist control. The experimental cyclic shearing response was modeled through the use of the Chaboche model, from which optimized constants are reported with build orientation; and the specimen deformation, under angle of twist control, was captured through a finite-element simulation model of the cylindrical gauge section of the specimens. Overall this study yields a comprehensive understanding of the experimental and modeled cyclic shearing response of an additively manufactured metal, which is vital to develop these components to be conducive for the multiaxial fatigue conditions to which they are subjected to in the gas turbine industry.

Estimation of the Packing density of solid polymers—III. Crystalline polymers

1962 ◽  
Vol 3 (6) ◽  
pp. 1139-1142 ◽  
Author(s):  
A.A. Tager ◽  
M.V. Tsilipotkina ◽  
D.M. Romanova
Keyword(s):  
Packing Density ◽  
Crystalline Polymers ◽  
Solid Polymers
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