scholarly journals Prediction of the Setting Properties of Calcium Phosphate Bone Cement

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Seyed Mahmud Rabiee ◽  
Hamid Baseri
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Bone Substitutes ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement ◽  
Poly Ethylene ◽  
Predicted Values ◽  
Inference Systems ◽  
Glycol Solution

Setting properties of bone substitutes are improved using an injectable system. The injectable bone graft substitutes can be molded to the shape of the bone cavity and set in situ when injected. Such system is useful for surgical operation. The powder part of the injectable bone cement is included ofβ-tricalcium phosphate, calcium carbonate, and dicalcium phosphate and the liquid part contains poly ethylene glycol solution with different concentrations. In this way, prediction of the mechanical properties, setting times, and injectability helps to optimize the calcium phosphate bone cement properties. The objective of this study is development of three different adaptive neurofuzzy inference systems (ANFISs) for estimation of compression strength, setting time, and injectability using the data generated based on experimental observations. The input parameters of models are polyethylene glycol percent and liquid/powder ratio. Comparison of the predicted values and measured data indicates that the ANFIS model has an acceptable performance to the estimation of calcium phosphate bone cement properties.

Physicochemical and Mechanical Properties of Composite of Chitosan Microspheres/Calcium Phosphate Cement

2007 ◽  
Vol 336-338 ◽  
pp. 1654-1657
Author(s):  
Rui Liu ◽  
Li Min Dong ◽  
Qing Feng Zan ◽  
Chen Wang ◽  
Jie Mo Tian
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Chemical Properties ◽  
Phase Evolution ◽  
Chitosan Microspheres ◽  
Setting Times ◽  
Calcium Phosphate Bone Cement

The aim of this work is to improve the mechanical properties of calcium phosphate bone cement (CPC) by appending chitosan microspheres to CPC base. That chitosan degrades rapidly than bone cement has been proved by previous investigations. Porous CPC has low compressive strength because of the pores in it weakening the structure. Additive chitosan microspheres can improve the mechanical properties by bearing the compress with the CPC base and produce pores after degradation. This study investigates the effect of chitosan microspheres on the setting time, mechanical properties, phase evolution and morphology of CPC. The additive proportion of chitosan microspheres ranges from 0 wt% to 30 wt%. Compared with original CPC, the modified CPC has higher compressive strength, without significantly affecting the chemical properties. The phase composition of the CPC is tested by XRD. The microstructures of CPC are observed using SEM. The final setting times range from 5~15 minutes and can be modulated by using different liquid and powder (L/P) ratio.

scholarly journals Photoluminescent Eu3+-Doped Calcium Phosphate Bone Cement and Its Mechanical Properties

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1610 ◽  
Author(s):  
Annemarie Oesterle ◽  
Anne Boehm ◽  
Frank Müller
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Setting Time ◽  
Bone Cements ◽  
X Ray ◽  
Novel Approach ◽  
Calcium Phosphate Bone Cement ◽  
Negative Effect ◽  
Healing Processes

Calcium phosphate cements (CPC) are well-established bone replacement materials that have been used in dentistry and orthopedics for more than 25 years. The monitoring of bone cements and the associated healing processes in the human body is difficult and so far has often been achieved using cytotoxic X-ray contrast agent additives. These additives have a negative effect on the mechanical properties and setting time of the bone cement. In this paper, we present a novel approach to prepare contrastive CPC by the incorporation of luminescent Eu3+-doped hydroxyapatite (Eu:HAp) nanoparticles. Eu-doped CPC (Eu:CPC) exhibited enhanced mechanical properties compared to pure CPC. Furthermore, the red photoluminescence of Eu:CPC may allow the observation of CPC-related healing processes without the use of harmful ionizing radiation.

scholarly journals Effect of Gold Nanoparticles and Silicon on the Bioactivity and Antibacterial Properties of Hydroxyapatite/Chitosan/Tricalcium Phosphate-Based Biomicroconcretes

Materials ◽  
2021 ◽  
Vol 14 (14) ◽  
pp. 3854
Author(s):  
Joanna Czechowska ◽  
Ewelina Cichoń ◽  
Anna Belcarz ◽  
Anna Ślósarczyk ◽  
Aneta Zima
Keyword(s):  
Gold Nanoparticles ◽  
Antibacterial Activity ◽  
Tricalcium Phosphate ◽  
Setting Time ◽  
Antibacterial Properties ◽  
Bone Substitutes ◽  
Bacterial Strains ◽  
Setting Times ◽  
Biological Studies

Bioactive, chemically bonded bone substitutes with antibacterial properties are highly recommended for medical applications. In this study, biomicroconcretes, composed of silicon modified (Si-αTCP) or non-modified α-tricalcium phosphate (αTCP), as well as hybrid hydroxyapatite/chitosan granules non-modified and modified with gold nanoparticles (AuNPs), were designed. The developed biomicroconcretes were supposed to combine the dual functions of antibacterial activity and bone defect repair. The chemical and phase composition, microstructure, setting times, mechanical strength, and in vitro bioactive potential of the composites were examined. Furthermore, on the basis of the American Association of Textile Chemists and Colorists test (AATCC 100), adapted for chemically bonded materials, the antibacterial activity of the biomicroconcretes against S. epidermidis, E. coli, and S. aureus was evaluated. All biomicroconcretes were surgically handy and revealed good adhesion between the hybrid granules and calcium phosphate-based matrix. Furthermore, they possessed acceptable setting times and mechanical properties. It has been stated that materials containing AuNPs set faster and possess a slightly higher compressive strength (3.4 ± 0.7 MPa). The modification of αTCP with silicon led to a favorable decrease of the final setting time to 10 min. Furthermore, it has been shown that materials modified with AuNPs and silicon possessed an enhanced bioactivity. The antibacterial properties of all of the developed biomicroconcretes against the tested bacterial strains due to the presence of both chitosan and Au were confirmed. The material modified simultaneously with AuNPs and silicon seems to be the most promising candidate for further biological studies.

Phosphoserine – a convenient compound for modification of calcium phosphate bone cement collagen composites

2004 ◽  
Vol 15 (4) ◽  
pp. 451-455 ◽  
Author(s):  
A. Reinstorf ◽  
M. Ruhnow ◽  
M. Gelinsky ◽  
W. Pompe ◽  
U. Hempel ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Calcium Phosphate Bone Cement

Recent Developments on Injectable Calcium Phosphate Bone Cement

2017 ◽  
Vol 9 (2) ◽  
pp. 72-94 ◽  
Author(s):  
Sufiamie Hablee ◽  
Nurul Razali ◽  
Asep Alqap ◽  
Iis Sopyan
Keyword(s):  
Calcium Phosphate ◽  
Bone Cement ◽  
Calcium Phosphate Bone Cement ◽  
Recent Developments

Effect of calcium carbonate on the compliance of an apatitic calcium phosphate bone cement

Biomaterials ◽  
1997 ◽  
Vol 18 (23) ◽  
pp. 1535-1539 ◽  
Author(s):  
I. Khairoun ◽  
M.G. Boltong ◽  
F.C.M. Driessens ◽  
J.A. Planell
Keyword(s):  
Calcium Carbonate ◽  
Calcium Phosphate ◽  
Bone Cement ◽  
Calcium Phosphate Bone Cement
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