scholarly journals Association between a Primitive Brain Tumor and Cerebral Aspergillosis

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Siegfried Hélage ◽  
Charles Duyckaerts ◽  
Danielle Seilhean ◽  
Jean-Jacques Hauw ◽  
Jacques Chiras

Cerebral aspergillosis is a rare pathology of poor prognosis in spite of the use of adapted antifungal treatments. This infection of the central nervous system is generally the complication of an invasive aspergillosis with hematogenic scattering from pulmonary focal spots. It can arise in immunocompetent patients treated with prolonged corticotherapy or chemoradiotherapy for cancer. A case of lethal cerebral aspergillosis in a patient with an infiltrative glioma treated with corticotherapy and radiotherapy is reported. Clinicopathological aspects and therapeutic approach are described.

PEDIATRICS ◽  
1959 ◽  
Vol 23 (1) ◽  
pp. 40-45
Author(s):  
Laurence Finberg

Seven infants with hypernatremic dehydration developed subdural effusions or bleeding. One of these was a previously normal infant accidentally poisoned by excessive ingestion of salt. This infant and five of the others had significant neurologic damage, ranging from moderate to severe. It appears that the hypernatremic dehydration was responsible for the subdural lesions in these patients and responsible for permanent damage in at least three of them. Changes in chemical anatomy and lesions of the cerebral vessels are discussed with regard to producing lesions of the central nervous system in hypernatremic dehydration. At present no salutary therapeutic approach to the complication of subdural effusions occurring during hypernatremic dehydration has been found.


1913 ◽  
Vol 13 (3-4) ◽  
pp. 224-241
Author(s):  
F. Ya. Chistovich ◽  
V. P. Pervushin

The case of cystic multiple brain tumor described below is of interest in two relationships: in clinical because it gave a reason for surgical intervention for the purpose of diagnostics and for the sake of removal of a brain tumor, the exact localization of which presented significant difficulties; In the pathological and anatomical relationship, this case deserves attention both because of the multiplicity of brain tumors, and due to their completely unusual structure, which deviates from these types of neoplasms, which usually serve as the starting point in the development of the cysts of the central nervous system.


2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e13035-e13035
Author(s):  
Edwin Boelke ◽  
Christiane Matuschek ◽  
Lawrence E. Ginsberg ◽  
Sujit S. Prabhu ◽  
Wilfried Budach ◽  
...  

e13035 Background: Primary brain and central nervous system (CNS) tumor incidence is approximately 19 per 100,000 individuals per year in the United States (US) compared with 7 per 100,000 individuals worldwide. The most common intra-axial tumor is gliomas, which account for 32% of all primary CNS tumors and 80% of all malignant tumors of the CNS.The most common diffuse glioma is grade 4 astrocytoma (glioblastoma, GBM), which makes up 54% of diffuse glial tumors. GBM is also the most aggressive brain tumor with poor prognosis.GBM metastases outside the CNS are rare, so therapeutic experience with these types of tumors is limited. Methods: Herein, we present 3 GBM patients with extra-CNS metastasis. Results: One patient developed GBM metastasis in the lung and pleura 5 years after his GBM diagnosis had been confirmed. Another patient who underwent resection of the primary GBM developed disease that extended through the sphenoid to involve the orbit and skull and subsequently invaded the parotid gland and neck nodes 1 year after diagnosis. A third patient developed GBM metastasis in the skull and L5 vertebra 2 years after her primary brain tumor had been resected. Conclusions: The exact mechanism of GBM metastasis outside the central nervous system is not well understood but likely involves the invasion of structures such as bone, lymphatics, and vasculature, especially veins. Above-average survival time and repeated surgical intervention may place GBM patients at higher risk for these unusual metastases.


2007 ◽  
Vol 65 (4a) ◽  
pp. 1030-1033 ◽  
Author(s):  
Marcelo Maroco Cruzeiro ◽  
Thiago Cardoso Vale ◽  
Leopoldo Antônio Pires ◽  
Gláucio Mendes Franco

Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory disorder of the central nervous system with both poor prognosis and high mortality. The disease has been related to a persistent and aberrant measles virus infection and no effective treatment has been available. We report a case of SSPE with atypical features including seizures at onset and a fulminant course in a 8 years-old boy who had been previously immunized against measles.


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