scholarly journals Neuroticism in Young Women with Fibromyalgia Links to Key Clinical Features

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Katrina Malin ◽  
Geoffrey Owen Littlejohn
Keyword(s):  
Clinical Features ◽  
Young Women ◽  
Big Five ◽  
Personality Trait ◽  
Clinical Symptoms ◽  
Healthy Controls ◽  
Psychological Processes ◽  
Psychological Variables ◽  
Significant Difference ◽  
The Common

Objective. We examined personality traits in young women with FM, in order to seek associations with key psychological processes and clinical symptoms. Methods. Twenty-seven women with FM and 29 age-matched female healthy controls [HC] completed a series of questionnaires examining FM symptoms, personality and psychological variables. Results. Significant differences between characteristic FM symptoms (sleep, pain, fatigue, and confusion) as well as for the psychological variables of depression, anxiety, and stress were found between FM and HC (P<0.001). Neuroticism was the only subscale of the Big Five Inventory that showed a significant difference between the FM group and HC group [P<0.05]. Within the FM group, there was a significant association between the level of the neuroticism and each of pain, sleep, fatigue, and confusion, depression, anxiety, and stress (P<0.05–0.01). The association between the level of neuroticism and the level of stress was the strongest of all variables tested (P<0.001). Conclusion. The personality trait of neuroticism significantly associates with the key FM characteristics of pain, sleep, fatigue and confusion as well as the common co-morbidities of depression, anxiety and stress. Personality appears to be an important modulator of FM clinical symptoms.

scholarly journals Decision making under ambiguity and risk in adolescent-onset schizophrenia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dandan Li ◽  
Fengyan Zhang ◽  
Lu Wang ◽  
Yifan Zhang ◽  
Tingting Yang ◽  
...  
Keyword(s):  
Decision Making ◽  
Executive Function ◽  
Iowa Gambling Task ◽  
Clinical Symptoms ◽  
Healthy Controls ◽  
Syndrome Scale ◽  
Significant Difference ◽  
Abnormal Pattern ◽  
Negative Syndrome ◽  
The Relationship

Abstract Objective Numerous studies have identified impaired decision making (DM) under both ambiguity and risk in adult patients with schizophrenia. However, the assessment of DM in patients with adolescent-onset schizophrenia (AOS) has been challenging as a result of the instability and heterogeneity of manifestations. The Iowa Gambling Task (IGT) and Game of Dice Task (GDT), which are frequently used to evaluate DM respectively under ambiguity and risk, are sensitive to adolescents and neuropsychiatric patients. Our research intended to examine the performance of DM in a relatively large sample of patients with AOS using the above-mentioned two tasks. We also aimed to take a closer look at the relationship between DM and symptom severity of schizophrenia. Methods We compared the performance of DM in 71 patients with AOS and 53 well-matched healthy controls using IGT for DM under ambiguity and GDT for DM under risk through net scores, total scores and feedback ration. Neuropsychological tests were conducted in all participants. Clinical symptoms were evaluated by using Positive and Negative Syndrome Scale (PANSS) in 71 patients with AOS. Pearson’s correlation revealed the relationship among total score of DM and clinical and neuropsychological data. Results Compared to healthy controls, patients with AOS failed to show learning effect and had a significant difference on the 5th block in IGT and conducted more disadvantageous choices as well as exhibited worse negative feedback rate in GDT. Apart from DM impairment under risk, diminished DM abilities under ambiguity were found related to poor executive function in AOS in the present study. Conclusions Our findings unveiled the abnormal pattern of DM in AOS, mainly reflected under the risky condition, extending the knowledge on the performance of DM under ambiguity and risk in AOS. Inefficient DM under risk may account for the lagging impulse control and the combined effects of developmental disease. In addition, our study demonstrated that the performance on IGT was related to executive function in AOS.

scholarly journals Image Mosaic Algorithm-Based Analysis of Pathological Characteristics of Gastric Polyp Patients Using Computed Tomography Images

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Xiqi Zhu ◽  
Jian Jiang ◽  
Jian Wang ◽  
Yue Tang ◽  
Xiaoming Ge
Keyword(s):  
Clinical Symptoms ◽  
Abdominal Distension ◽  
Ct Images ◽  
Gastric Polyp ◽  
Image Mosaic ◽  
Image Splicing ◽  
Pathological Characteristics ◽  
Computed Tomography Images ◽  
Significant Difference ◽  
The Common

The application value of image mosaic algorithm (IMA) based CT imaging technology in the analysis of pathological characteristics of gastric polyp (GP) patients was explored in this work. 588 cases of GP patients in the hospital were selected as the research objects, and CT images based on IMA were adopted for examination. The patient’s basic information, image performance, and gastroscopy results were recorded. The results showed that the absolute mean bright error (AMBE) index and information entropy of the IMA are 0.0625 and 7.0385, respectively. The clinical symptoms of patients were mostly abdominal pain (21.4%), abdominal distension (15.6%), and sour regurgitation (17.8%). The common size of GP was no more than 0.5 cm, and the common type was Yamada type II. There were notable differences between single and multiple GPs of different pathological types ( P < 0.05 ). Proliferative polyps were mostly found in the stomach and antrum, while fundus gland polyps were mostly in the stomach and fundus. There was significant difference between the growth location of the hyperplastic polyp and basal gland polyp ( P < 0.05 ). In summary, the CT images of IMA proposed in this paper can not only realize image splicing effectively but also were superior to the traditional SIFT method in the quality of splicing image and were conducive to the analysis of the pathological characteristics of GP patients, which had significant clinical promotion value.

scholarly journals Association Between Serum Insulin-Like Growth Factor 1 Levels and the Clinical Symptoms of Chronic Schizophrenia: Preliminary Findings

2021 ◽  
Vol 12 ◽  
Author(s):  
Naomichi Okamoto ◽  
Koji Yoshino ◽  
Shogo Kitagawa ◽  
Rintaro Fujii ◽  
Shinsuke Hamada ◽  
...  
Keyword(s):  
Growth Factor ◽  
Environmental Health ◽  
Clinical Symptoms ◽  
Psychiatric Symptoms ◽  
Serum Insulin ◽  
Chronic Schizophrenia ◽  
Healthy Controls ◽  
Insulin Like Growth Factor ◽  
Significant Difference ◽  
The University

Purpose: Insulin-like growth factor 1 (IGF-1) is a trophic mediator that is regulated by growth hormone and associated with the proliferation, development, and growth of neural cells. IGF-1 may be associated with the pathophysiology of schizophrenia, but this association remains controversial. This study aimed to investigate the relationship between serum IGF-1 levels and psychiatric symptoms in patients with chronic schizophrenia.Patients and Methods: A total of 65 patients were recruited from the University of Occupational and Environmental Health, Komine Eto Hospital, Moji Matsugae Hospital, Shin-Moji Hospital, and Tsutsumi Hospital in Kitakyushu between September 2019 and June 2020. Further, 20 healthy age- and sex-matched control participants were recruited from the Komine Eto Hospital and the University of Occupational and Environmental Health. Patients with schizophrenia were assessed using the Positive and Negative Syndrome Scale (PANSS) and the Drug-Induced Extrapyramidal Symptoms Scale. Serum levels of free plus albumin-bound IGF-1 (IGF-1) were measured by immunoradiometric assay. The measurements were performed using antibody beads for bound/free separation. Associations between serum IGF-1 levels and the PANSS scores were determined. We also examined the associations between serum IGF-1 levels and diabetes, antipsychotic drug use, and disease duration.Results: No significant difference was found in the serum IGF-1 level between patients with schizophrenia and healthy controls. Serum IGF-1 levels were significantly negatively correlated with the PANSS total score (R2 = 0.06, p = 0.015) and PANSS general score (R2 = 0.088, p = 0.008), but not with the PANSS positive scores and PANSS negative scores. Serum IGF-1 levels were not related to the prevalence of diabetes (p = 0.64). However, a significant correlation was observed between serum IGF-1 levels and age (B = −1.88, p &lt; 0.0001). Serum IGF-1 levels could not distinguish patients with schizophrenia and healthy controls.Conclusion: The association between serum IGF-1 levels and psychiatric symptoms may be complicated in patients with chronic schizophrenia.

scholarly journals Clinical features and outcome of fecal retention in infancy

2020 ◽  
Author(s):  
Lu Ren ◽  
Lan-Lan Geng ◽  
hong-li Wang ◽  
si-tang Gong ◽  
Jing Xie ◽  
...  
Keyword(s):  
Medical Record ◽  
Electronic Medical Record ◽  
Clinical Features ◽  
Clinical Symptoms ◽  
Gastrointestinal Symptoms ◽  
Treatment Rate ◽  
Record System ◽  
Significant Difference ◽  
Normal Defecation

Abstract 1) Background: To understand the clinical features and outcome of fecal retention in infancy(FRI), so as to guide the focus and intervention methods of such infants.2) Methods: The electronic medical record system(EMRS)was used to collect and screen out cases diagnosed as fecal retention from June 2018 to June 2019 in outpatient clinic of our hospital. The age, feeding method, frequency and traits of stool, and accompanying symptoms were recorded. The changes of clinical symptoms, medical examinations and drug treatment by the age of 1 year were investigated by means of electronic medical record review and telephone follow-up.3) Results: A total of 286 infants were enrolled, 7 were lost to follow-up, and 279 were effectively followed up. There were 157 males and 129 females, with an age of 3.6 ± 1.5 months. The average stool frequency was 5.9 ± 1.8 days. 63.3% of the infants were breast-fed, 16.8% were formula-fed, and the rest were mixed-fed,all without supplementary food. 9.1% of the infants showed corresponding gastrointestinal symptoms, such as bloating, increased crying, decreased milk intake, and laborious defecation. 87.1% of the infants received medical treatment, including glycerin enema, probiotics, and Chinese herbal preparations, with an effective treatment rate of 7.8%. 38.7% of infants have undergone medical examination, including abdominal ultrasound, X-ray film / barium enema, blood test, etc, the positive rate is 14.8%. The duration of fecal retention in 53% of infants was ≤ 2 months, 22.6% between 2–3 months, 24.4% ≥ 3 months, with an average of 2.6 ± 1.1 months. At the age of followed up to 1 year, 16.8% of infants developed functional constipation(FC). Compared with other infants with normal defecation, there was no significant difference in age, frequency of stool, the proportion of breast milk feeding and receiving treatment, and there was a significant difference in the duration of fecal retention. The duration of FC group was longer than normal defecation group by which was 3.49 ± 0.83 months.4) Conclusions: Infants with fecal retention are more likely to develop FC at age 1 than general population, and may be positively related to the duration of fecal retention.

scholarly journals Stereopsis deficits in patients with schizophrenia in a Han Chinese population

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Li Hui ◽  
Hai Sen Xia ◽  
An Shu Tang ◽  
Yi Feng Zhou ◽  
Guang Zhong Yin ◽  
...  
Keyword(s):  
Chinese Population ◽  
Negative Symptoms ◽  
Clinical Symptoms ◽  
Three Dimensional ◽  
Han Chinese ◽  
Healthy Controls ◽  
Han Chinese Population ◽  
Significant Difference ◽  
Marked Deficit ◽  
Positive And Negative Symptoms

Abstract Although cognitive and sensory deficits have been identified as a core feature of schizophrenia, only a small portion of visual sensorium has been explored. To date, studies on visual system of three-dimensional percepts based on two-dimensional information still are limited. This study is the first to examine the integrity of stereopsis of schizophrenia in a Han Chinese population, and to further investigate the correlation of stereopsis with clinical symptoms. 100 patients with schizophrenia and 80 healthy controls were recruited. We assessed stereoacuity using the Titmus Stereopsis Test and clinical symptoms using Chinese versions of the Scales for the Assessment of Positive and Negative Symptoms (SAPS and SANS). There was a significant difference in log seconds of arc between two groups (p < 0.0001). The percentage of patients with correct stereopsis detection was significantly reduced at 400, 200, 140, 100, 80, 60, 50, and 40 seconds of arc than healthy controls (all, p < 0.01). Log seconds of arc in patients was not correlated with total scores and subscores of SAPS and SANS (all, p > 0.05). Our findings support that patients with schizophrenia have a marked deficit of stereopsis in a Han Chinese population. However, clinical symptoms do not influence stereopsis of schizophrenia.

scholarly journals The Correlation Between Asthma Severity and Neutrophil to Lymphocyte Ratio

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Meena Abdul-Sattar Darwesh ◽  
Ibtihal Shukri Abd Alhaleem ◽  
Muhammed Waheeb Salman Al-Obaidy
Keyword(s):  
Clinical Symptoms ◽  
Asthma Severity ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Healthy Controls ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Asthmatic Patients ◽  
Significant Difference

Background—The prognosis is essential in management and follows up of asthmatic patients. Neutrophil to lymphocyte ratio is considered as the common prognostic marker for many diseases especially the asthma. Aim of study—To assess the relationship between asthma severity and neutrophil to lymphocyte ratio in comparison to healthy controls. Patients and methods—This study is a cross sectional study conducted in Respiratory Consultancy Clinic in Baghdad Teaching Hospital in Medical City during the period from 1st of October, 2018 to 31st of March, 2019 on sample of 50 asthmatic patients and 50 healthy controls. The diagnosis of asthma was confirmed by the supervisor through clinical symptoms, signs, spirometery with reversibility test (according to GINA guideline.). Results—A highly significant difference was observed between asthmatic cases and controls regarding age (p<0.001). A significant association was observed between obesity and asthmatic cases (p=0.001). There was a highly significant association between high neutrophil/lymphocyte ratio and asthmatic cases (p<0.001). The neutrophil/lymphocyte ratio was significantly increased with advanced age, females, severe and uncontrolled asthma. Conclusions—The neutrophil to lymphocyte ratio is useful biomarker in assessment of asthma severity.

scholarly journals Clinical symptoms and psychological changes of patients with COVID-19 in Jiangxi Province

2020 ◽  
Author(s):  
Jing Zhou ◽  
Xin-Ping Xu ◽  
Fei Xu ◽  
Yi Shao ◽  
Mei-Hong Zou ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Severe Infection ◽  
Depression Score ◽  
Anxiety Score ◽  
Blood Type ◽  
Jiangxi Province ◽  
Healthy Controls ◽  
Amyloid A ◽  
Significant Difference

Abstract Objective The purpose of this study was to determine the prevalence and differences in etiology, clinical manifestations, and psychological activity of coronavirus disease-19 (COVID-19) among patients. Results We recruited 90 subjects, 30 were healthy controls, 30 were patients with moderate infection, and 30 were patients with severe/critical infections. No significant differences were noted in the sex ratio, mean age, body mass index, or blood type; however, the history of exposure of the patients with COVID-19 compared with healthy controls was noteworthy. The erythrocyte sedimentation rate, as well as the levels of C-reactive protein and serum amyloid A (SAA) were all increased. In terms of mental health, there were significant differences in the worry scores between severely and moderately infected patients and healthy controls. There was a significant difference in depression scores between patients with moderate infection and healthy hypertension, and there was also a significant difference in dream worry scores. Analysis of the Mini-Mental State Examination scores showed that for patients with moderate infection, the depression score was moderately and positively correlated with the dream anxiety score. For patients with severe infection, the anxiety score was positively correlated with the dream anxiety score, and the depression score was moderately and positively correlated with the dream anxiety score. Conclusion Patients with severe infection showed increased pain and sputum in the pharyngeal area compared with patients with moderate infection. Patients with blood type A may be more susceptible to COVID-19, and lymphopenia may indicate worsening of COVID-19.

scholarly journals Clinical Features and Survival Outcome of Early-Stage Primary Pulmonary MALT Lymphoma After Surgical Treatment

2021 ◽  
Vol 8 ◽  
Author(s):  
Ye Xu ◽  
Min Zheng ◽  
Qingkui Guo ◽  
Ning Wang ◽  
Rui Wang
Keyword(s):  
Clinical Features ◽  
Malt Lymphoma ◽  
Clinical Symptoms ◽  
Early Stage ◽  
Univariate Analysis ◽  
Tumor Stage ◽  
Good Prognosis ◽  
Rank Test ◽  
Significant Difference ◽  
Pulmonary Malt Lymphoma

Background: We aimed to study the clinical features and survival outcomes of patients with early-stage primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma who underwent surgery.Methods: This is a retrospective, single-center study including 32 patients with early-stage primary pulmonary MALT lymphoma. Univariate and multivariate Cox analyses were performed to select independent prognostic factors. The overall survival (OS) was analyzed by the Kaplan-Meier method and was compared with the log-rank test.Results: Among the 32 patients included, there were 16 men (50.0%) and 16 women (50.0%). The average age was 59.2 years old. Ten patients had non-specific clinical symptoms including cough, expectoration, and chest pain, and four patients had B symptoms. CT images are not specific and can be shown as peripheral, central, solid, and ground glass but more peripheral (93.8%) and solid (75.0%). In prognostic analysis, univariate analysis showed that tumor stage and size were associated with relapse-free survival (RFS) and OS [hazard ratio (HR) = 1.105, 95% CI: 1.021–1.197, P = 0.011; HR = 1.211, 95% CI: 1.158–1.968, P = 0.003, respectively]. It seems to indicate that higher stage and larger size indicate a worse prognosis, but we could not find statistically significant predictors in multivariate analysis. Sublobectomy was performed in 21 (65.6) cases, lobectomy was performed in the other 11 (34.4) cases, both of them can achieve good prognosis (5-year RFS and OS are both 100%), and there is no significant difference between them.Conclusions: The clinical manifestation of early-stage primary pulmonary MALT lymphoma is not significantly specific, and surgical resection is an effective treatment.

scholarly journals Adiponectin as a novel biomarker of disease severity in alopecia areata

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anna Stochmal ◽  
Anna Waśkiel-Burnat ◽  
Sylwia Chrostowska ◽  
Michał Zaremba ◽  
Adriana Rakowska ◽  
...  
Keyword(s):  
Serum Level ◽  
Negative Correlation ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Enzyme Linked Immunosorbent Assay ◽  
Healthy Controls ◽  
Significant Difference ◽  
The Common ◽  
Loss Severity

AbstractThe frequent coexistence of obesity and metabolic syndrome in patients with alopecia areata may indicate the common pathogenetic pathway in these conditions with an important role of adipokines. The aim of the study was to evaluate the serum level of adiponectin, resistin and leptin in patients with alopecia areata in comparison to healthy controls. The study included 65 patients with alopecia areata and 71 healthy controls. The concentration of adipokines was determined with the enzyme-linked immunosorbent assay. The mean concentrations of adiponectin and resistin were significantly lower in the sera of patients with alopecia areata when compared to healthy controls (7966 $$\pm$$ ± 4087 vs 9947 $$\pm$$ ± 5692 ng/ml; p = 0.0312 and 11.04 $$\pm$$ ± 3.88 vs 14.11 $$\pm$$ ± 8.69 ng/ml; p = 0.0176, respectively). A negative correlation between the serum level of adiponectin and severity of alopecia tool (SALT) score was observed (r = − 0.26; p < 0.05). The concentration of adiponectin was significantly lower in patients with alopecia universalis than in patients with patchy alopecia areata (4951 $$\pm$$ ± 2499 vs 8525 $$\pm$$ ± 4085 ng/ml; p = 0.0135). No significant difference in the serum concentration of leptin was observed between patients with alopecia areata and healthy controls. The negative correlation between the serum level of adiponectin and hair loss severity indicates that adiponectin may be considered a marker of hair loss severity in alopecia areata. Further studies are needed to evaluate the role of resistin in patients with alopecia areata and its decreased level irregardless of severity or activity of the disease.

scholarly journals FELICIDAD SUBJETIVA, SENTIDO DEL HUMOR Y PERSONALIDAD EN LA DOCENCIA

2017 ◽  
Vol 3 (1) ◽  
pp. 401
Author(s):  
Lucía Herrera Torres ◽  
Teresa María Perandones González
Keyword(s):  
Big Five ◽  
Personality Trait ◽  
Teaching Experience ◽  
Subjective Happiness ◽  
Psychological Variables ◽  
Big Five Inventory ◽  
Subjective Happiness Scale ◽  
Positive Correlations ◽  
Educación Primaria ◽  
The Relationship

Abstract.SUBJECTIVE HAPPINESS, HUMOR SENSE, AND PERSONALITY IN TEACHINGThe research aims to analyze, firstly, the relationship between different psychological variables of the teachers, that is, subjective happiness, sense of humor and personality. Secondly, to determine the factorial structure of these variables. 454 teachers (24.4% males and 65.6% females), with a mean age of 40.4 years (SD = 10.50) and an average teaching experience of 14.03 years, took part in the study. 15% worked in Early Childhood Education (n = 68), 26.2% in Primary Education (n = 119), 43.6% in Secondary Education (n = 198) and 15.2% in Higher Education (n = 69). The instruments used were the following: Subjective Happiness Scale (SHS), Multidimensional Humor Sense Scale (MSHS), and Big Five Inventory-10 items (BFI-10). The results derived from the correlation analysis indicated positive correlations between the different dimensions analyzed, except for the Neuroticism personality trait, in which they were negative. In addition, factorial analysis showed three factors: A first factor formed by the different components of the Humor Sense and the personality trait of Extraversion; a second factor that integrated subjective happiness, the personality trait of Agreeableness and Emotional Stability (the opposite of Neuroticism); and a third factor that included the personality traits of Conscientiousness and Openness to experience. The need to address these psychological variables in the professional development of the teacher is discussed.Keywords: Subjective Happiness, Humor Sense, Personality, TeachersResumen. La investigación pretende analizar, en primer lugar, la relación que existe entre diferentes variables psicológicas de los docentes, esto es, felicidad subjetiva, sentido del humor y personalidad. En segundo lugar, determinar la estructura factorial de dichas variables. Formaron parte del estudio 454 docentes (24.4% hombres y 65.6% mujeres), con una edad media de 40.4 años (DT = 10.50) y una experiencia profesional media de 14.03 años. El 15% trabajaba en Educación Infantil (n = 68), el 26.2% en Educación Primaria (n = 119), el 43.6% en Educación Secundaria (n = 198) y el 15.2% en Educación Superior (n = 69). Los instrumentos empleados fueron los siguientes: la Escala de Felicidad Subjetiva (Subjective Happiness Scale, SHS), la Escala Multidimensional del Sentido del Humor (Multidimensional Humor Sense Scale, MSHS) y el Inventario de Personalidad de los Cinco Factores (Big Five Inventory-10 ítems, BFI-10). Los resultados derivados del análisis correlacional indicaron correlaciones positivas entre las diferentes dimensiones analizadas, excepto para el rasgo de personalidad Neuroticismo, donde fueron negativas. Además, el análisis factorial mostró tres factores: un primer factor formado por los diferentes componentes del sentido del humor y el rasgo de personalidad de extraversión; un segundo factor que integraba el bienestar subjetivo, el rasgo de personalidad de amabilidad y el de estabilidad emocional (el opuesto a Neuroticismo); y un tercer factor que incluía los rasgos de personalidad de responsabilidad y apertura a la experiencias. Se discute la necesidad de atender a estas variables psicológicas en el desarrollo profesional del docente.Palabras clave: felicidad subjetiva, sentido del humor, personalidad, docentes

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