scholarly journals Gestational Diabetes Mellitus: A Positive Predictor of Type 2 Diabetes?

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Gregory E. Rice ◽  
Sebastian E. Illanes ◽  
Murray D. Mitchell
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Disease Onset ◽  
First Trimester ◽  
Global Pandemic ◽  
Develop Type ◽  
Type Two Diabetes

The aim of this paper is to consider the relative benefits of screening for type two diabetes mellitus in women with a previous pregnancy complicated by gestational diabetes mellitus. Recent studies suggest that women who experience GDM are at a greater risk of developing type 2 diabetes within 10–20 years of their index pregnancy. If considered as a stand-alone indicator of the risk of developing type 2 diabetes, GDM is a poor diagnostic test. Most women do not develop GDM during pregnancy and of those that do most do not develop type 2 diabetes. There is, however, a clear need for better early detection of predisposition to disease and/or disease onset to significantly impact on this global pandemic. The putative benefits of multivariate approaches and first trimester and preconception screening to increase the sensitivity of risk assignment modalities for type 2 diabetes are proposed.

scholarly journals Gestational Diabetes Mellitus (GDM): Current concept and a short Review

1970 ◽  
Vol 24 (1) ◽  
pp. 16-20 ◽  
Author(s):  
MT Rahman ◽  
T Tahmin ◽  
S Ferdousi ◽  
SN Bela
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Later Life ◽  
Short Review ◽  
Current Concept ◽  
Increased Risk ◽  
Develop Type

Gestational Diabetes Mellitus (GDM) is a very common and important disease occurring during pregnancy and has detrimental effect on both the mother and the baby. The mother is at increased risk of developing obstetric complications like prolonged labour, prone to develop type 2 diabetes in future and the baby is born with overweight, cause of childhood obesity and later life development of type 2 diabetes. A short review and current concept of GDM is discussed. Key words: GDM, Type 2 diabetes, Obesity, Macrosomia, Complications   doi: 10.3329/bjpath.v24i1.2877 Bangladesh J Pathol 24 (1) : 16-20

Gestational Diabetes Mellitus

2020 ◽  
Author(s):  
Ellen W. Seely ◽  
Chloe A. Zera
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Glucose Intolerance ◽  
First Trimester ◽  
Keywords Gestational Diabetes ◽  
Obstetric Management ◽  
In Pregnancy

Gestational diabetes mellitus (GDM) has historically been defined as glucose intolerance first identified during pregnancy. The definition fails to distinguish overt (pre-gestational) diabetes diagnosed during pregnancy from glucose intolerance induced by pregnancy. Recently, the recognition that overt diabetes may first be identified in pregnancy has led to the recommendation that diabetes diagnosed in the first trimester should be termed type 2 diabetes (T2DM) rather than GDM , a clinically relevant difference in terminology as the outcomes and management of T2DM in pregnancy are distinct from outcomes and management of GDM. This chapter discusses the epidemiology, pathophysiology, screening, diagnosis, treatment and impact of GDM, as well as the obstetric management of GDM and management of GDM after pregnancy.  This review contains 8 tables, and 56 references. Keywords: Gestational diabetes mellitus, diabetes mellitus, stillbirth, glucose control, type 2 diabetes mellitus, pregnancy

scholarly journals Elevated first trimester C-reactive protein as a predictor of gestational diabetes

2019 ◽  
Vol 6 (5) ◽  
pp. 1482
Author(s):  
Sanjay Parihar ◽  
Rajesh Singh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
First Trimester ◽  
Antenatal Visit ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
First Trimester Of Pregnancy

Background: The incidence of type 2 diabetes is increasing at an alarming rate, particularly among young women. GDM is a unique prediabetes state that shares common risk factors with type 2 diabetes, and similar alterations in carbohydrate metabolism. Objectives of this study the elevation of C-reactive protein in the first trimester of pregnancy as a predictor of gestational diabetes.Methods: This hospital-based study comprised of patients (Primigravida) visiting the obstetric OPD or admitted in Obstetric wards. Detailed history and clinical examination of the patient was recorded on a Proforma. Blood samples of patients were taken for: (i) C-reactive protein in first trimester of pregnancy; and (ii) Blood sugar (fasting & post-prandial) during their first antenatal visit and patients were followed up in subsequent visits in second and third trimester for development of gestational diabetes.Results: There were seven women who developed gestational diabetes and had elevated first trimester C- reactive protein levels as compared to other group in which only two women developed gestational diabetes mellitus but did not have elevated C-reactive protein in their first trimester. However, there were two women, who had elevated C-reactive protein, but did not subsequently develop gestational diabetes mellitus and women with C-reactive protein in normal range who did not develop gestational diabetes mellitus were 56.Conclusion: An association between first trimester inflammation marked by increased CRP levels, and subsequent risk of development of GDM has been identified.

scholarly journals Lactation Duration and Long-term Risk for Incident Type 2 Diabetes in Women With a History of Gestational Diabetes Mellitus

Diabetes Care ◽  
2020 ◽  
Vol 43 (4) ◽  
pp. 793-798 ◽  
Author(s):  
Sylvia H. Ley ◽  
Jorge E. Chavarro ◽  
Mengying Li ◽  
Wei Bao ◽  
Stefanie N. Hinkle ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Incident Type ◽  
Incident Type 2 Diabetes ◽  
History Of ◽  
Lactation Duration
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