scholarly journals Primary Leiomyosarcoma of Bone: Analysis of Prognosis

Sarcoma ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
P. Brewer ◽  
V. Sumathi ◽  
R. J. Grimer ◽  
S. R. Carter ◽  
R. M. Tillman ◽  
...  

Leiomyosarcoma of bone is just one of the variants of spindle cell sarcoma of bone characterised by the expression of desmin and other markers indicating a significant element of smooth muscle in the tumour, without osteoid production we have investigated the management and outcome of this rare type of primary malignant bone tumour.Method. Retrospective review of data stored on a prospective database.Results. In a database of 3364 patients with primary malignant bone sarcomas, 31 patients were identified with a primary leiomyosarcoma of bone. There were 12 males and 19 females with a mean age of 46 and tumour size of 8 cm. The most common site was the distal femur followed by the proximal tibia. Treatment was with chemotherapy and surgical resection. Seven of the patients had metastases at diagnosis. Surgery was carried out in 28 patients, 8 having amputation and 20 limb salvage. Three patients developed local recurrence, but half developed metastases. All patient disease-specific survival was 57% at five years and 44% at 10 yrs but for those without metastases was 82% and 60%, respectively. The only prognostic factors were metastases at diagnosis.Conclusion. Leiomyosarcoma of bone is a very rare primary malignant bone tumour affecting a predominantly older population. Despite the high incidence of metastases, survival is better than for other bone sarcomas for those without metastases at diagnosis.

2017 ◽  
Vol 99-B (9) ◽  
pp. 1244-1249 ◽  
Author(s):  
V. Cladière-Nassif ◽  
C. Bourdet ◽  
V. Audard ◽  
A. Babinet ◽  
P. Anract ◽  
...  

2017 ◽  
Vol 99-B (9) ◽  
pp. 1244-1249
Author(s):  
V. Cladière-Nassif ◽  
C. Bourdet ◽  
V. Audard ◽  
A. Babinet ◽  
P. Anract ◽  
...  

2014 ◽  
Vol 18 (3) ◽  
pp. 267-272 ◽  
Author(s):  
Christel A.H.P. van Riel ◽  
Esther E.M. Meijer-van den Bergh ◽  
Hennie L.M. Kemps ◽  
Ton Feuth ◽  
Hendrik W.B. Schreuder ◽  
...  

2004 ◽  
Vol 21 (4) ◽  
Author(s):  
AB Omololu ◽  
JO Ogunbiyi ◽  
SO Ogunlade ◽  
TO Alonge ◽  
A Adebisi ◽  
...  

2018 ◽  
Vol 2 (2) ◽  
pp. 41
Author(s):  
OscarIndra Kusuma ◽  
CynthiaDewi Sinardja ◽  
TjokordaGde Agung Senapathi ◽  
IPutu Pramana Suarjaya ◽  
IWayan Suranadi ◽  
...  

2017 ◽  
Vol 99-B (9) ◽  
pp. 1244-1249
Author(s):  
V. Cladière-Nassif ◽  
C. Bourdet ◽  
V. Audard ◽  
A. Babinet ◽  
P. Anract ◽  
...  

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
G. L. Tiemeier ◽  
J. M. Brown ◽  
S. E. Pratap ◽  
C. McCarthy ◽  
A. Kastrenopoulou ◽  
...  

2020 ◽  
Vol 21 (2) ◽  
pp. 105-110
Author(s):  
Md Shawkat Alam ◽  
Sudip Das Gupta ◽  
Hadi Zia Uddin Ahmed ◽  
Md Saruar Alam ◽  
Sharif Muhammod Wasimuddin

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110


2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Rachna Agarwal ◽  
Ritu Khatuja ◽  
Lipi Sharma ◽  
Alpana Singh

Introduction. A rare case of histologically proven placental mesenchymal dysplasia (PMD) with fetal omphalocele in a 22-year-old patient is reported.Material and Methods. Antenatal ultrasound of this patient showed hydropic placenta with a live fetus of 17 weeks period of gestation associated with omphalocele. Cordocentesis detected the diploid karyotype of the fetus. Patient, when prognosticated, choose to terminate the pregnancy in view of high incidence of fetal and placental anomalies. Subsequent histopathological examination of placenta established the diagnosis to be placental mesenchymal dysplasia.Conclusion. On clinical and ultrasonic grounds, suspicion of P.M.D. arises when hydropic placenta with a live fetus presents in second trimester of pregnancy. Cordocentesis can detect the diploid karyotype of the fetus in such cases. As this condition is prognostically better than triploid partial mole, continuation of pregnancy can sometimes be considered after through antenatal screening and patient counseling. However, a definite diagnosis of P.M.D. is made only on placental histology by absence of trophoblast hyperplasia and trophoblastic inclusions.


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