scholarly journals The Traditional Chinese Medicine Prescription Pattern of Endometriosis Patients in Taiwan: A Population-Based Study

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Ruei-Chi Fang ◽  
Yueh-Ting Tsai ◽  
Jung-Nien Lai ◽  
Chia-Hao Yeh ◽  
Chien-Tung Wu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Symptom Relief ◽  
Healthcare Providers ◽  
Population Based ◽  
Reproductive Age ◽  
Research Database ◽  
Herbal Products ◽  
Chinese Herbal ◽  
Medicine Prescription

Background. Traditional Chinese medicine (TCM), when given for symptom relief, has gained widespread popularity among women with endometriosis. The aim of this study was to analyze the utilization of TCM among women with endometriosis in Taiwan.Methods. The usage, frequency of service, and the Chinese herbal products prescribed for endometriosis, among endometriosis patients, were evaluated using a randomly sampled cohort of 1,000,000 beneficiaries recruited from the National Health Insurance Research Database.Results. Overall, 90.8% (N=12,788) of reproductive age women with endometriosis utilized TCM and 25.2% of them sought TCM with the intention of treating their endometriosis-related symptoms. Apart from the usage of either analgesics or more than one type of medical treatment, the odds of using TCM and Western medicine were similar in all types of conventional endometriosis treatment. However, endometriosis patients suffering from symptoms associated with endometriosis were more likely to seek TCM treatment than those with no symptoms. There were 21,056 TCM visits due to endometriosis and its related symptoms, of which more than 98% were treated with Chinese herbal products (CHPs).Conclusion.Gui-Zhi-Fu-Ling-Wan(Cinnamon Twig and Poria Pill) containing sedative and anti-inflammatory agents is the most commonly prescribed Chinese herbal formula mainly for the treatment of endometriosis-related symptomatic discomfort and the effects of these TCMs should be taken into account by healthcare providers.

scholarly journals Traditional Chinese Medicine Use among Patients with Psoriasis in Taiwan: A Nationwide Population-Based Study

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Shu-Wen Weng ◽  
Bor-Chyuan Chen ◽  
Yu-Chiao Wang ◽  
Chun-Kai Liu ◽  
Mao-Feng Sun ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Population Based ◽  
Research Database ◽  
Newly Diagnosed ◽  
Population Based Study ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
White Collar Workers ◽  
Median Interval

Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. We identified 28,510 patients newly diagnosed with psoriasis between 2000 and 2010. Among them, 20,084 (70.4%) patients were TCM users. Patients who were female, younger, white-collar workers and lived in urbanized area tended to be TCM users. The median interval between the initial diagnosis of psoriasis to the first TCM consultation was 12 months. More than half (N=11,609; 57.8%) of the TCM users received only Chinese herbal medicine. Win-qing-yin and Bai-xian-pi were the most commonly prescribed Chinese herbal formula and single herb, respectively. The core prescription pattern comprised Mu-dan-pi, Wen-qing-yin, Zi-cao, Bai-xian-pi, and Di-fu-zi. Patients preferred TCM than Western medicine consultations when they had metabolic syndrome, hepatitis, rheumatoid arthritis, alopecia areata, Crohn’s disease, cancer, depression, fatty liver, chronic airway obstruction, sleep disorder, and allergic rhinitis. In conclusion, TCM use is popular among patients with psoriasis in Taiwan. Future clinical trials to investigate its efficacy are warranted.

scholarly journals Prescription Pattern of Chinese Herbal Products for Breast Cancer in Taiwan: A Population-Based Study

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Jung-Nien Lai ◽  
Chien-Tung Wu ◽  
Jung-Der Wang
Keyword(s):  
Breast Cancer ◽  
Panax Ginseng ◽  
Synergistic Effects ◽  
Symptom Relief ◽  
Healthcare Providers ◽  
Angelica Sinensis ◽  
Research Database ◽  
Herbal Products ◽  
Chinese Herbal ◽  
Angelica Sinensis Radix

Background. Chinese herbal products (CHPs) given as a therapy for symptom relief have gained widespread popularity among women with breast cancer. The aim of this study was to analyze the utilization of CHP among women with breast cancer in Taiwan.Methods. The usage, frequency of services, and CHP prescribed for breast cancer among women with breast cancer were evaluated, recruited from a randomly sampled cohort of 1,000,000 beneficiaries from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs) for utilization of CHP.Results. 81.5 percent (N=2,236) of women with breast cancer utilized traditional Chinese medicine (TCM) and 18% of them sought TCM with the intent of treating their breast cancer. Jia-wei-xiao-yao-san (Augmented Rambling Powder) was the most frequently prescribed formula for treating breast cancer. Among the top 10 most frequently prescribed CHP for treating breast cancer, seven contained dang qui (Angelica sinensis-radix) and six contained ren shen (Panax ginseng-radix), which are reported to have potential beneficial synergistic effects on breast cancer cells.Conclusion. CHP containing dang qui (Angelica sinensis-radix) or ren shen (Panax ginseng-radix) are the most frequently prescribed for breast cancer and their effects should be taken into account by healthcare providers.

scholarly journals Utilization Pattern of Traditional Chinese Medicine among Fracture Patients: A Taiwan Hospital-Based Cross-Sectional Study

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Chu-Yao Tseng ◽  
Ching-Wen Huang ◽  
Hsin-Chia Huang ◽  
Wei-Chen Tseng
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Early Period ◽  
Clinic Visit ◽  
Research Database ◽  
Late Period ◽  
Utilization Pattern ◽  
Cross Sectional ◽  
Herbal Products ◽  
Tcm Theory

Traditional Chinese medicine (TCM) divides fracture treatment into three stages. Many TCM herbs and formulas have been used to treat fractures for thousands of years. However, research regarding the Chinese herbal products (CHPs) that should be used at different periods of treatment is still lacking. This study aims to identify the CHPs that should be used at different periods of treatment as well as confirm the TCM theory of fracture periods medicine. We used prescriptions of TCM outpatients with fracture diagnoses analyzed using the Chang Gung Research Database (CGRD) from 2000 to 2015. According to the number of days between the date of the fracture and the clinic visit date, all patients were assigned to one of three groups. Patients with a date gap of 0-13 days were assigned to the early period group; those with a date gap of 14-82 days were assigned to the middle period group; and those with a date gap of 83-182 days were assigned to the late period group. We observed the average number of herbal formulas prescribed by the TCM doctor at each visit was 2.78, and the average number of single herbs prescribed was 6.47. The top three prescriptions in the early fracture period were Zheng-gu-zi-jin-dang, Shu-jing-huo-xue-tang, and Wu-ling-san. In the middle fracture period, the top three formulas were Zheng-gu-zi-jin-dang, Shu-jing-huo-xue-tang, and Zhi-bai-di-huang-wan. In the late fracture period, the top three formulas were Shu-jing-huo-xue-tang, Gui-lu-er-xian-jiao, and Du-huo-ji-sheng-tang. The main single herbs used in the early fracture period were Yan-hu-suo, Gu-sui-bu, and Dan-shen. From the middle to the late period, the most prescribed single herbs were Xu-duan, Gu-sui-bu, and Yan-hu-suo. We concluded that the results showed that the CGRD utilization pattern roughly meets the TCM theory at different fracture periods.

scholarly journals Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Yang Xin Zi Xu ◽  
Shengyan Xi ◽  
Xiaoyan Qian
Keyword(s):  
Diabetes Mellitus ◽  
Chinese Medicine ◽  
Herbal Medicine ◽  
Traditional Chinese Medicine ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Symptom Relief ◽  
Care Providers ◽  
Herbal Products ◽  
Health Maintenance

Gestational diabetes mellitus is the most common metabolic disorder during pregnancy with health consequences for both lives during and after pregnancy. Studies found that many pregnant women turn to complementary and alternative medicine for health maintenance or symptom relief, such as herbal medicine and acupuncture from traditional Chinese medicine. With the growing popularity of traditional Chinese medicine, we conducted a systemic search in PubMed, Web of Science, and Embase databases on research studies that investigated traditional Chinese medicine during pregnancy. The resultant hits were further searched in relation to all diabetes mellitus. In total, we found three major herbal medicine/herbal products that were associated with glycemic control in gestational diabetes, including Zuo Gui Wan, red raspberry leaves, and Orthosiphon stamineus. We further reviewed them and their relatives in relation to type 2 diabetes mellitus and found more evidence of metabolic benefits. None of the herbal medicine and products examined reported toxicity in the experimental models. Overall, treatments of gestational diabetes by western or alternative interventions are grossly understudied. It is critical to have a standardized protocol when evaluating efficacy of herbal medicine and produce quality results for women and their health-care providers to make informed treatment decisions.

scholarly journals The Prescription Pattern of Chinese Herbal Products ContainingGinsengamong Tamoxifen-Treated Female Breast Cancer Survivors in Taiwan: A Population-Based Study

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Wei-Lung Hsu ◽  
Yueh-Ting Tsai ◽  
Chien-Tung Wu ◽  
Jung-Nien Lai
Keyword(s):  
Breast Cancer ◽  
Endometrial Cancer ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Population Based ◽  
Interactive Effects ◽  
Tamoxifen Treatment ◽  
Research Database ◽  
Herbal Products ◽  
Chinese Herbal

Background.The purpose of our study is to analyze the association between prescribed Chinese herbal products (CHPs) containingGinsengand the risk of endometrial cancer among tamoxifen (TMX) users and to identify any possible interactive effects betweenGinsengand TMX with respect to preventing the development of subsequent endometrial cancer in an estrogen-dependent breast cancer population in Taiwan.Methods.All patients newly diagnosed with invasive breast cancer receiving tamoxifen treatment from January 1, 1998, to December 31, 2008, were selected from the National Health Insurance Research Database. The usage, frequency of service, and CHP-Ginsengprescribed across the 30,556 TMX-treated breast cancer (BC) survivors were evaluated. Logistic regression was employed to estimate the odds ratios (ORs) for the utilization of CHP-Ginseng. Cox’s proportional hazard regression was performed to calculate the hazard ratios (HRs) for endometrial cancer associated withGinsenguse among the TMX-treated BC cohort.Results.The HR for the development of endometrial cancer among breast cancer survivors who had ever takenGinsengafter TXM treatment was significantly decreased compared to those who never used CHP.Conclusion.A significant inhibitory relationship betweenGinsengconsumption and subsequent endometrial cancer less than 2 years after TMX treatment was detected among BC survivors.

scholarly journals Concurrent Use in Taiwan of Chinese Herbal Medicine Therapies among Hormone Users Aged 55 Years to 79 Years and Its Association with Breast Cancer Risk: A Population-Based Study

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yueh-Ting Tsai ◽  
Jung-Nien Lai ◽  
Chien-Tung Wu ◽  
Shun-Ku Lin
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Proportional Hazards ◽  
Population Based ◽  
Cox Proportional Hazards ◽  
Research Database ◽  
Herbal Products ◽  
Chinese Herbal ◽  
Concurrent Use

Background. The purpose of the present study was to analyze the concurrent use of Chinese herbal products (CHPs) among women aged 55 to 79 years who had also been prescribed hormonal therapies (HT) and its association with breast cancer risk.Methods. The use, frequency of service, and CHP prescribed among 17,583 HT users were evaluated from a random sample of 1 million beneficiaries from the National Health Insurance Research Database. A logistic regression method was used to identify the factors that were associated with the coprescription of a CHP and HT. Cox proportional hazards regressions were performed to calculate the hazard ratios (HRs) of breast cancer between the TCM nonusers and women who had undergone coadministration of HT and a CHP or CHPs.Results. More than one out of every five study subjects used a CHP concurrently with HT (CHTCHP patients).Shu-Jing-Huo-Xie-Tangwas the most commonly used CHP coadministered with HT. In comparison to HT-alone users, the HRs for invasive breast cancer among CHTCHP patients were not significantly increased either in E-alone group or in mixed regimen group.Conclusions. The coadministration of hormone regimen and CHPs did not increase the risk of breast cancer.

scholarly journals Chinese Herbal Products for Non-Motor Symptoms of Parkinson’s Disease in Taiwan: A Population-Based Study

2021 ◽  
Vol 11 ◽  
Author(s):  
Chien-Hung Lin ◽  
Hsienhsueh Elley Chiu ◽  
Szu-Ying Wu ◽  
Shih-Ting Tseng ◽  
Tzu-Chan Wu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Population Based ◽  
Research Database ◽  
Motor Symptoms ◽  
Neuroprotective Effects ◽  
Herbal Products ◽  
Logistic Regression Models ◽  
Chinese Herbal ◽  
Non Motor Symptoms

Objective: Combinations of Chinese herbal products (CHPs) are widely used for Parkinson’s disease (PD) in Taiwan. Thereby, we investigated the use of CHPs in patients with PD.Methods: This study was a population-based cohort study that analyzed the data of patients with PD from the National Health Insurance Research Database. A total of 9,117 patients were selected from a random sample of one million individuals included in this database. We used multiple logistic regression models to estimate the adjusted odds ratios of the demographic factors and analyzed the formula and single CHPs commonly used for PD.Results: Traditional Chinese medicine users were more commonly female, younger, of white-collar status, and residents of Central Taiwan. Chaihu-Jia-Longgu-Muli-Tang was the most commonly used formula, followed by Ma-Zi-Ren-Wan and then Shao-Yao-Gan-Cao-Tang. The most commonly used single herb was Uncaria tomentosa (Willd. ex Schult.) DC., followed by Gastrodia elata Blume and then Radix et Rhizoma Rhei (Rheum palmatum L., Rheum tanguticum Maxim. ex Balf., and Rheum officinale Baill.). Chaihu-Jia-Longgu-Muli-Tang and U. tomentosa (Willd. ex Schult.) DC. have shown neuroprotective effects in previous studies, and they have been used for managing non-motor symptoms of PD.Conclusion: Chaihu-Jia-Longgu-Muli-Tang and U. tomentosa (Willd. ex Schult.) DC. are the most commonly used CHPs for PD in Taiwan. Our results revealed the preferences in medication prescriptions for PD. Further studies are warranted to determine the effectiveness of these CHPs for ameliorating the various symptoms of PD, their adverse effects, and the mechanisms underlying their associated neuroprotective effects.

scholarly journals Prescription Patterns of Chinese Herbal Products for Osteoporosis in Taiwan: A Population-Based Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Wei-Tai Shih ◽  
Yao-Hsu Yang ◽  
Pau-Chung Chen
Keyword(s):  
Population Based ◽  
Research Database ◽  
Herbal Formula ◽  
Efficacy And Safety ◽  
Population Based Study ◽  
Herbal Products ◽  
Treatment Of Osteoporosis ◽  
Prescription Patterns ◽  
Chinese Herbal ◽  
Prevalence Of Osteoporosis

Background. Traditional Chinese medicine (TCM) includes Chinese herbal products (CHPs), acupuncture, and traumatology manipulative therapies. TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used and their patterns of prescriptions have yet to be characterized. This study, therefore, aimed to evaluate the CHP used for the treatment of osteoporosis in Taiwan and their prescription patterns.Methods. A cohort of one million randomly sampled cases from the National Health Insurance Research Database (NHIRD) was analyzed to evaluate the frequencies and percentages of herbal formula and single herb prescriptions for osteoporosis. Association rules were then applied to evaluate the CHP coprescription patterns and the prevalence of osteoporosis.Results. The osteoporosis cohort included 16 544 patients, of whom more than 70% had used TCM on one or more occasion. Of these patients, 4 292 (25.9%) had been hospitalized at least once because of fracture. Du-Huo-Ji-Sheng-Tang and Du Zhong (Cortex Eucommiae) were the most frequently prescribed herbal formula and single herb, respectively, for the treatment of osteoporosis.Conclusion. This study identified patterns of CHP use for the treatment of osteoporosis. However, further research is required to fully elucidate the efficacy and safety of these CHP.

scholarly journals Traditional Chinese Medicine Reduces Hospitalization Risk of Osteoarthritis Patients: A 13- Year Population-based Cohort Study

2021 ◽  
Author(s):  
Yanping Zhao ◽  
Shuya Wang ◽  
James Cheng-Chung Wei ◽  
Yu Hsun Wang ◽  
Zhiyi Zhang
Keyword(s):  
Logistic Regression ◽  
Cohort Study ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Population Based ◽  
Hospitalization Rate ◽  
Study Patient ◽  
Research Database ◽  
Medical Expense

Abstract Introduction：Osteoarthritis (OA) is a chronic musculoskeletal disorder of the movable joints. TCM has been widely used as complementary therapy for OA in Chinese. Traditional Chinese medicine (TCM) including Duhuojishi decoction, Shujing Huoxue decoction, Angelica Niantong decoction, Guilu Erxian glue et al are widely used in the clinical of osteoarthritis treatment. However there are very few large-scale studies about long-term effect of TCM on OA treatment. This study determined the long-term effects of TCM on reducing OA patients hospitalization risk.Material and methods: This study was a population-based retrospective cohort study. Patient data were collected from the claim-based Taiwan National Health Insurance Research Database from 2000 to 2012. We enrolled 67737 TCM treated cohort and 67737 non-TCM comparison of newly diagnosed OA patients. Propensity score matching was done on age, sex and possible confounders to ensure baseline comparability. Outcomes were medical utility, including hospitalization rate, emergency visits and direct medical expense. Logistic regression was conducted to compare the differences o between TCM and non-TCM groups. Subgroup analyses were also performed by age, gender, income and urbanization.Results: TCM group had an overall higher medical expense than non-TCM group. Although Logistic regression analysis results showed that there was no difference of emergency rate in TCM group and non-TCM group, TCM treatment reduced hospitalization rate of OA significantly.Conclusions: The usage of TCM was associated with a reduced risk of hospitalization of OA patients. TCM might play a complementary role in OA treatment.

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