scholarly journals History, Present, and Progress of Frontotemporal Dementia in China: A Systematic Review

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Ru-Jing Ren ◽  
Yue Huang ◽  
Gang Xu ◽  
Chun-Bo Li ◽  
Qi Cheng ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Age Of Onset ◽  
Case Reports ◽  
Small Sample ◽  
Current Status ◽  
Future Research ◽  
Clinical Presentations ◽  
Neuropathological Diagnosis ◽  
Future Research Directions ◽  
Small Sample Sizes

We aim to provide an overview of clinical and demographical features and neuropathological research on frontotemporal dementia (FTD) from China over the past decade. We reviewed the demographic features, clinical presentations, and neuropathology of the FTD-spectrum disorders from the 49 cases in China published since 1998. On the basis of these findings, we retrospect the history and speculate on future progress in terms of FTD in China. We found that most published papers comprise case reports with a few retrospective studies with small sample sizes. Behavior variant FTD (bvFTD) was the most common diagnostic subtype, of which 35% were associated with amyotrophic lateral sclerosis or Parkinsonian syndrome. More than 47% patients with FTD had age onset before 65. There were no differences in age of onset and sex distribution between diagnostic subtypes. The spectrum of neuropathological diagnosis of bvFTD was frontotemporal lobe degeneration (FTLD) with tau protein or ubiquitin-immunopositive inclusions, and FTLD without intracellular inclusions. Median survival in bvFTD was 14 years. This paper provides an overview of the current status and pointers for future research directions of FTD in China.

scholarly journals Sleep Spindle Characteristics in Children with Neurodevelopmental Disorders and Their Relation to Cognition

2016 ◽  
Vol 2016 ◽  
pp. 1-27 ◽  
Author(s):  
Reut Gruber ◽  
Merrill S. Wise
Keyword(s):  
Cognitive Function ◽  
Neurodevelopmental Disorders ◽  
Sleep Problems ◽  
Small Sample ◽  
Future Research ◽  
Sleep Spindles ◽  
Sleep Spindle ◽  
High Prevalence ◽  
Future Research Directions ◽  
Small Sample Sizes

Empirical evidence indicates that sleep spindles facilitate neuroplasticity and “off-line” processing during sleep, which supports learning, memory consolidation, and intellectual performance. Children with neurodevelopmental disorders (NDDs) exhibit characteristics that may increase both the risk for and vulnerability to abnormal spindle generation. Despite the high prevalence of sleep problems and cognitive deficits in children with NDD, only a few studies have examined the putative association between spindle characteristics and cognitive function. This paper reviews the literature regarding sleep spindle characteristics in children with NDD and their relation to cognition in light of what is known in typically developing children and based on the available evidence regarding children with NDD. We integrate available data, identify gaps in understanding, and recommend future research directions. Collectively, studies are limited by small sample sizes, heterogeneous populations with multiple comorbidities, and nonstandardized methods for collecting and analyzing findings. These limitations notwithstanding, the evidence suggests that future studies should examine associations between sleep spindle characteristics and cognitive function in children with and without NDD, and preliminary findings raise the intriguing question of whether enhancement or manipulation of sleep spindles could improve sleep-dependent memory and other aspects of cognitive function in this population.

Tourism research for the GCC region: Current status and future research directions

2021 ◽  
pp. 135481662199996
Author(s):  
Ali Salman Saleh ◽  
Charbel Bassil ◽  
Arsalan Safari
Keyword(s):  
United Arab Emirates ◽  
Current Status ◽  
Future Research ◽  
Research Directions ◽  
Regional Tourism ◽  
Research Theme ◽  
Tourism Sector ◽  
Future Research Directions ◽  
Meta Analyses ◽  
The Impact

Tourism in the Gulf Cooperation Council (GCC) countries has recently been considered by policymakers as a new avenue for economic diversification. Despite the considerable literature concerning the impact of tourism worldwide, only a limited number of studies have looked at the tourism sector in the GCC region or analyzed its economic, sociocultural, and environmental impacts. This article therefore conducts a systematic review of the state of the literature related to tourism in the GCC region. It provides effective insights about the current status, gaps, and challenges and proposes future research directions in this area for academics, practitioners, and policymakers with an interest in regional tourism development. The preferred reporting items for systematic reviews and meta-analyses approach was used to identify and select the papers. Some 23 papers were identified and analyzed. The majority of these studies focused on the United Arab Emirates, specifically the Dubai emirate. We found the most dominant research theme to be tourism planning.

Sustainability and Design Education: The Current Status of Product Design Higher Education in the UK

2021 ◽  
Author(s):  
Emelia Delaney ◽  
Wei Liu
Keyword(s):  
Higher Education ◽  
Product Design ◽  
New Product Development ◽  
Design Education ◽  
Current Status ◽  
Design Stage ◽  
Future Research ◽  
Future Research Directions ◽  
Area Of Concern ◽  
The Uk

Abstract The aim of sustainability is to fulfil the needs of current generations without compromising the needs of future generations. It is also a rising area of concern within industry, it is therefore important that graduate designers are equipped with the skills to accommodate sustainability issues as well as demands from industry. Additionally, the product design stage during New Product Development has been identified to have the greatest impact on the sustainability of the entire product, however how educated designers are on the topic of sustainability is unclear. An initial literature review has been conducted to investigate design education on sustainability as well as teaching styles. Following this the study identifies and reviews UK Product Design courses to establish the current status of sustainability integration in higher education. The exploration into university prospectuses has found that around half of UK universities implement sustainability in some way, however there are limited courses which dedicate specific modules to sustainability. Additionally, links with industry and accreditation organizations between UK product design courses have been confirmed, but there is no definite information to suggest that the universities use this to aid in the implementation sustainability education. From this review future research directions have been outlined.

scholarly journals 3D Printing in Construction: Current Status, Implementation Hindrances, and Development Agenda

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Xin Ning ◽  
Tong Liu ◽  
Chunlin Wu ◽  
Chao Wang
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Current Status ◽  
Future Research ◽  
Research Directions ◽  
Technical Research ◽  
Research Status ◽  
Development Agenda ◽  
Future Research Directions ◽  
Future Topics

3D printing (3DP) is regarded as an innovation that contributes to automation in civil engineering and offers benefits in design, greenness, and efficiency. It is necessary to objectively analyze the current status and challenges associated with 3DP and identify future research directions to properly understand its construction applications. Previous research has focused more on the technical dimension of 3DP; however, the nontechnical dimension of the technology may hinder its implementation and thus must be paid particular attention to. This study presents a systematic review of the existing literature from both technical and nontechnical dimensions by combining quantitative and qualitative studies. The quantitative study was conducted using scientometric methods. The qualitative study analyzed information, including the technical research status and nontechnical challenges and trends. Two aspects of technical research status are presented, including materials and processes. In addition, nontechnical challenges and trends from the economic, environmental, social, and legislative aspects are proposed. This study provides a comprehensive agenda to advance 3DP in construction and proposes research interests, challenges, and future topics. It is intended to help construction practitioners systematically master existing processes and materials and assess the application degree and necessity of 3DP.

Big 4 Firms as Legal Service Providers: Implications for Audit Practice and Future Research Directions

2021 ◽  
Author(s):  
David N. Herda ◽  
Jonathan H. Grenier ◽  
Billy E. Brewster ◽  
Mary E Marshall
Keyword(s):  
Service Providers ◽  
Current Status ◽  
Future Research ◽  
Legal Services ◽  
Legal Service ◽  
Accounting Firms ◽  
Big 4 ◽  
Rule Changes ◽  
Future Research Directions ◽  
The U.S

The Big 4 accounting firms have expanded their legal service arms to historic proportions over the last decade, employing thousands of lawyers around the world. Although most of the Big 4's revenue from legal services is presently generated outside the U.S., they are now making inroads into the U.S. legal market, and rule changes are being considered that would further allow the Big 4 to offer legal services in the U.S. This essay summarizes the current status of Big 4 firms as legal service providers, discusses potential implications of legal offerings for their U.S. audit practices, and suggests directions for future research. Our proposed research questions are informed by several literatures, interviews with former Big 4 partners and practicing attorneys, and a survey of the general public. They center on the fundamental difference between audit and law practices, brand equity considerations, and culture changes within the Big 4.

Systematic Review of Pre-Injury Migraine Disorder as a Risk Factor for Worse Outcome Following Sport-Related Concussion

2019 ◽  
Vol 34 (5) ◽  
pp. 754-754
Author(s):  
D P Terry ◽  
A J Gardner ◽  
G L Iverson
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Age Of Onset ◽  
Small Sample ◽  
Self Report ◽  
Cochrane Library ◽  
Clinical Recovery ◽  
Other Information ◽  
Sport Athlete ◽  
Small Sample Sizes

Abstract Purpose This systematic review examined clinical outcomes (i.e., prognosis) following a sport-related concussion in athletes who have a pre-injury history of migraines. Clinical recovery was defined functionally as recovery from symptoms or full return to activities following injury. Data Selection All studies published prior to February 2019 that addressed pre-injury migraines as a possible predictor of clinical recovery from concussion were included. Broadly, the search included (i) sport/athlete-related terms, (ii) concussion-related terms, and (iii) diverse predictor/modifier terms. The following databases were utilized: PubMed, PsycINFO®, MEDLINE®, CINAHL, Cochrane Library, EMBASE, SPORTDiscus, Scopus, and Web of Science. After removing duplicates from the 9,372 identified articles, 5,888 abstracts were screened, 358 full-text articles were reviewed, and 15 articles examining pre-injury migraines as a predictor of recovery were included. Data Synthesis Most articles examined pre-injury migraines as an exploratory/secondary predictor of concussion outcome. Migraine history was predominantly based on self-report. Studies included minimal other information about this condition (e.g., age of onset, migraine frequency/severity, past treatment). Methodological rigor varied greatly across studies. Most studies did not find pre-injury migraines to be associated with concussion outcome, but several of these studies had small or very small sample sizes. Larger, better-designed studies suggested pre-injury migraines may be a risk factor for worse concussion outcome. Effect sizes were rarely reported or able to be calculated. Conclusion There is some evidence to suggest pre-injury migraines may be a vulnerability factor for a prolonged recovery following concussion. Future studies should focus on improving methodological quality when assessing the relationship between pre-injury migraines and concussion outcome.

scholarly journals Review of literature on decision support systems for natural hazard risk reduction: Current status and future research directions

2017 ◽  
Vol 96 ◽  
pp. 378-409 ◽  
Author(s):  
Jeffrey Peter Newman ◽  
Holger Robert Maier ◽  
Graeme Angus Riddell ◽  
Aaron Carlo Zecchin ◽  
James Edward Daniell ◽  
...  
Keyword(s):  
Decision Support ◽  
Decision Support Systems ◽  
Natural Hazard ◽  
Current Status ◽  
Future Research ◽  
Review Of Literature ◽  
Research Directions ◽  
Hazard Risk ◽  
Reduction Current ◽  
Future Research Directions
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