scholarly journals Bilateral Circumscribed Posterior Keratoconus: Visualization by Ultrasound Biomicroscopy and Slit-Scanning Topography Analysis

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Robert Rejdak ◽  
Katarzyna Nowomiejska ◽  
Dariusz Haszcz ◽  
Anselm G. M. Jünemann
Keyword(s):  
Cataract Surgery ◽  
Developmental Disorder ◽  
Corneal Thickness ◽  
Ultrasound Biomicroscopy ◽  
Corneal Curvature ◽  
Corneal Surface ◽  
Topography Analysis ◽  
First Time ◽  
Slit Scanning ◽  
Posterior Keratoconus

This paper documents a rare nonprogressive developmental disorder—bilateral circumscribed posterior keratoconus—in a 60-year-old man referred for a cataract surgery. For the first time ultrasound biomicroscopy was used to visualise the local anterior bulging of the posterior corneal surface with concomitant thinning of the stroma. The amount of localized posterior depression, corneal thickness and the refractive power of both the posterior and anterior corneal curvature were measured using slit-scanning topography analysis (Orbscan).

scholarly journals Agreement Analysis of LENSTAR With Other Four Techniques of Biometry Before Cataract Surgery.

2021 ◽  
Author(s):  
Jinling Zhang ◽  
Yong Wang
Keyword(s):  
Cataract Surgery ◽  
Pearson Correlation ◽  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Anterior Chamber Depth ◽  
Correlation Coefficients ◽  
Preoperative Assessment ◽  
Ultrasound Biomicroscopy ◽  
Intraclass Correlation Coefficients ◽  
Axis Length

Abstract Purpose: To test whether some biometry measurements provided by the Lenstar LS900 compared well with the AL-Scan, Pentacam rotating Scheimpflug camera, Ultrasound Biomicroscopy (UBM) and Tomey EM-3000. Methods: 201 patients having routine cataract surgery had standard preoperative assessment. In this clinical study, the axis length (AL) and lens thickness (LT) were taken by Lenstar LS900 and AL-Scan; anterior chamber depth (ACD) were taken by Lenstar LS900, A-scan, Pentacam and UBM; central corneal thickness (CCT) were taken by Lenstar LS900, Pentacam and Tomey EM-3000. The results were compared using a Wilcoxon-Mann-Whitney U test and Pearson correlation calculations. Agreement was assessed through intraclass correlation coefficients and Bland-Altman plots.Results: The highest correlation was found between Lenstar and AL-Scan for AL (r = 0.975; P <0.001). For LT measurements, the correlation between these two devices was also good (r = 0.699; P <0.001). Excellent correlations were showed between Lenstar and pentacam or UBM for ACD (r=0.948, 0.704, respectively; both P <0.001), but AL-scan (r=0.453, P <0.001). According to CCT, correlation between Lenstar and Pentacam or Tomey EM-3000 were both excellent (r=0.817, 0.882, respectively; both P <0.001).Conclusions: In phakic eyes of cataract patients, measurements of AL, LT, ACD, and CCT from Lenstar LS900 yielded results that correlated very well with other clinical instruments.

Ultrasound Biomicroscopy Documented Anterior Uveal Melanoma Regression after Ruthenium-106 Plaque Therapy

2021 ◽  
pp. 1-9
Author(s):  
Biljana Kuzmanović Elabjer ◽  
Mladen Bušić ◽  
Andrej Pleše ◽  
Mirjana Bjeloš ◽  
Daliborka Miletić ◽  
...  
Keyword(s):  
Uveal Melanoma ◽  
Tumor Regression ◽  
Corneal Thickness ◽  
Case Series ◽  
Ultrasound Biomicroscopy ◽  
Close Monitoring ◽  
Single Institution ◽  
Retrospective Case ◽  
Caucasian Patients

<b><i>Introduction:</i></b> Ultrasound biomicroscopy (UBM) is the only widely used method for the evaluation of anterior uveal melanoma (AUM). <b><i>Objective:</i></b> Documentation of regression of AUM treated with ruthenium-106 (Ru-106) plaque types CCB and CCC using UBM. <b><i>Methods:</i></b> This single institution-based retrospective case series involved 10 Caucasian patients with AUM followed after brachytherapy with UBM from January 2014 until February 2019. The largest prominence of the tumor perpendicular to the sclera or the cornea (including scleral/corneal thickness) (<i>D</i>) and the largest basal dimension (<i>B</i>) were measured in millimeters with UBM for all patients prior to the brachytherapy and at 4-month interval follow-up. Tumor regression was calculated as a percentage of decrease in the initial <i>D</i> and <i>B</i> values. <b><i>Results:</i></b> The study involved 10 patients with a mean age of 64.4 years (yr) (range 46–80 yr). <i>D</i> ranged from 1.82 to 5.5 mm (median 2.99 mm) and <i>B</i> from 2.32 to 12.38 mm (median 4.18 mm). The apical radiation dose in all patients was 100 Gy. The median follow-up was 42.02 months. Regression for <i>D</i> was 21.11 ± 13.66%, 31.09 ± 14.66%, and 34.92 ± 19.86% at 1st, 2nd, and 3rd year of the follow-up, respectively, while for <i>B</i> it was 21.58 ± 16.05%, 28.98 ± 17.71%, and 32.06 ± 18.96%, respectively. Tumor recurrence was documented in 2/10 patients. <b><i>Conclusion:</i></b> The major regression of AUM, treated with Ru-106 plaque types CCB and CCC, was documented in the first 2 years after brachytherapy in our study group. In the following years, only minimal regression was documented that warns of the need for close monitoring and active search for local recurrences.

scholarly journals Combining QTL Mapping and Gene Expression Analysis to Elucidate the Genetic Control of ‘Crumbly’ Fruit in Red Raspberry (Rubus idaeus L.)

Agronomy ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 794
Author(s):  
Luca M. Scolari ◽  
Robert D. Hancock ◽  
Pete E. Hedley ◽  
Jenny Morris ◽  
Kay Smith ◽  
...  
Keyword(s):  
Genetic Control ◽  
Developmental Disorder ◽  
Molecular Mechanisms ◽  
Developmental Stages ◽  
Microarray Experiment ◽  
Rubus Idaeus ◽  
Red Raspberry ◽  
Genotype By Sequencing ◽  
First Time ◽  
Selection Of

‘Crumbly’ fruit is a developmental disorder in raspberry that results in malformed and unsaleable fruits. For the first time, we define two distinct crumbly phenotypes as part of this work. A consistent crumbly fruit phenotype affecting the majority of fruits every season, which we refer to as crumbly fruit disorder (CFD) and a second phenotype where symptoms vary across seasons as malformed fruit disorder (MFD). Here, segregation of crumbly fruit of the MFD phenotype was examined in a full-sib family and three QTL (Quantitative Trait Loci) were identified on a high density GbS (Genotype by Sequencing) linkage map. This included a new QTL and more accurate location of two previously identified QTLs. A microarray experiment using normal and crumbly fruit at three different developmental stages identified several genes that were differentially expressed between the crumbly and non-crumbly phenotypes within the three QTL. Analysis of gene function highlighted the importance of processes that compromise ovule fertilization as triggers of crumbly fruit. These candidate genes provided insights regarding the molecular mechanisms involved in the genetic control of crumbly fruit in red raspberry. This study will contribute to new breeding strategies and diagnostics through the selection of molecular markers associated with the crumbly trait.

Surface and Orbscan II slit-scanning elevation topography in circumscribed posterior keratoconus

2005 ◽  
Vol 31 (3) ◽  
pp. 636-639 ◽  
Author(s):  
Nicolás Charles ◽  
Martin Charles ◽  
Oscar J. Croxatto ◽  
Daniel E. Charles ◽  
Diego Wertheimer
Keyword(s):  
Orbscan Ii ◽  
Slit Scanning ◽  
Posterior Keratoconus

scholarly journals Evaluation of Anterior Chamber Depth in 28,709 Adult Cataract Patients in China using Swept-Source Optical Biometry

2021 ◽  
Author(s):  
Qiong Lei ◽  
Haixia Tu ◽  
Xi Feng ◽  
Yong Wang
Keyword(s):  
Cataract Surgery ◽  
Anterior Chamber ◽  
Axial Length ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Regression Analysis ◽  
Swept Source ◽  
Mean Values ◽  
The Mean ◽  
Cataract Patients

Abstract Background: To create an anterior chamber depth (ACD) regression model for adult cataract surgery candidates from China, and to evaluate the distribution of their ocular biometric parameters.Methods: The ocular biometric records of 28,709 right eyes of cataract surgery candidates who were treated at Aier Eye Hospitals in nine cities from 2018 to 2019 were retrospectively analyzed. All measurements were taken with IOLMaster 700. We included patients who were at least 40 years old and were diagnosed with cataract.Results: The mean age of the patients was 68.6 ± 11.0 years. The mean values recorded were as follows: axial length (AL), 24.17 ± 2.47 mm; mean keratometry (Km) value, 44.09 ± 3.25 D; corneal astigmatism (CA), 1.06 ± 0.98 D; ACD, 3.02 ± 0.45 mm; lens thickness (LT), 4.52 ± 0.45 mm; central corneal thickness (CCT), 0.534 ± 0.04 mm; and white to white (WTW) corneal diameter, 11.64 ± 0.46 mm. The proportion of patients with long axial length (AL >25 mm) decreased with age. ACD, LT, AL, Km, WTW, and age were correlated. In the multivariate regression analysis of ACD, which included LT, AL, WTW, sex, Km, CCT, and age, there was a reasonable prediction with adjusted R2 = 0.629.Conclusions: The results show that high myopes are inclined to schedule cataract surgery at a younger age. LT and AL were found to be important factors that affect ACD. This study provides reference data for cataract patients from China.

scholarly journals Two-step sclero-corneal tunnel incision for cataract surgery

2002 ◽  
Vol 1 (4) ◽  
pp. 92-96
Author(s):  
V. S. Neyasov ◽  
A. S. Ekimov
Keyword(s):  
Cataract Surgery ◽  
Corneal Curvature ◽  
Corneal Incision ◽  
Lens Extraction

The modification of small tunnel sclero-corneal incision for lens extraction is suggested. The influence of the incision on corneal curvature and its ability to provide intraoperative and postoperative eyeball hermeticity is experimentally studied.

scholarly journals Comparison of surgically induced astigmatism between anterior and total cornea in 2.2 mm steep meridian incision cataract surgery

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Young-chae Yoon ◽  
Minji Ha ◽  
Woong-Joo Whang
Keyword(s):  
Cataract Surgery ◽  
Intraocular Lens ◽  
Corneal Surface ◽  
Polar Plot ◽  
Mean Values ◽  
Surgically Induced Astigmatism ◽  
Induced Astigmatism ◽  
The Mean ◽  
Surgically Induced ◽  
Corneal Refractive Power

Abstract Background This study aimed to compare surgically induced astigmatism (SIA) on the anterior and total cornea during cataract surgery through a 2.2 mm steep meridian incision. Methods The study included 69 left eyes of 69 patients who had undergone cataract surgery. The 69 eyes were classified into three subgroups according to the preoperative steep meridian. Following phacoemulsification, an intraocular lens was inserted into the bag. The keratometric measurements were taken 12 months postoperatively, on the anterior cornea (automated keratometer and anterior keratometry [K] from a rotating Scheimpflug camera) and total cornea (equivalent K reading [EKR] 3.0 mm, EKR 4.5 mm, total corneal refractive power (TCRP) 2.0 mm ring, TCRP 3.0 mm zone, TCRP 4.0 mm zone). The SIA was analyzed for each parameter. Results On the double-angle polar plot, the summated vector mean values of SIA determined by the automated keratometer and Scheimpflug anterior K were 0.28 diopter (axis: 177°) and 0.37 diopter (axis: 175°) in with-the-rule (WTR) astigmatism; 0.03 diopter (axis: 156°) and 0.18 diopter (axis: 177°) in oblique astigmatism; 0.15 diopter (axis: 96°) and 0.17 diopter (axis: 73°) in against-the-rule (ATR) astigmatism. The mean SIAs on the total cornea ranged from 0.31 to 0.42 diopter in WTR astigmatism; from 0.16 to 0.27 diopter in oblique astigmatism; from 0.04 to 0.11 diopter in ATR astigmatism. Mean magnitude SIA ranged from 0.41 to 0.46 diopter on anterior corneal surface and 0.50 to 0.62 diopter on total cornea. J0 and J45 of the posterior cornea showed no significant changes after cataract surgery, and the changes in J0 and J45 did not show any statistical differences between the anterior and total cornea (all p > 0.05). Conclusions There were no differences in the summed vector mean values of SIA between the anterior cornea and the total cornea.

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