scholarly journals Chronic Cough, Reflux, Postnasal Drip Syndrome, and the Otolaryngologist

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Deborah C. Sylvester ◽  
Petros D. Karkos ◽  
Casey Vaughan ◽  
James Johnston ◽  
Raghav C. Dwivedi ◽  
...  

Objectives. Chronic cough is a multifactorial symptom that requires multidisciplinary approach. Over the last years, general practitioners refer increasingly more chronic cough patients directly to the otolaryngologist. The aim of this paper is to highlight the issues in diagnosis and management of chronic cough patients from the otolaryngologist perspective.Design. Literature review.Results. Gastroesophageal reflux and postnasal drip syndrome remain one of the most common causes of chronic cough. Better diagnostic modalities, noninvasive tests, and high technology radiological and endoscopic innovations have made diagnosis of these difficult-to-treat patients relatively easier. Multidisciplinary assessment has also meant that at least some of these cases can be dealt with confidently in one stop clinics.Conclusions. As the number of referrals of chronic cough patients to an Ear Nose Throat Clinic increases, the otolaryngologist plays a pivotal role in managing these difficult cases.

2003 ◽  
Vol 37 (11) ◽  
pp. 1607-1609 ◽  
Author(s):  
Mehran Howaizi ◽  
Christian Delafosse

OBJECTIVE: To report a case of chronic, persistent cough induced by omeprazole therapy. CASE SUMMARY: A 42-year-old white woman presented with chronic, persistent cough after omeprazole initiation for treatment of postoperative heartburn. The cough was permanent, dry, and exhausting and worsened at night. Omeprazole therapy was continued for 4 months because the persistent cough was thought to be related to gastroesophageal reflux disease (GERD). However, no cause of persistent, chronic cough was identified. After omeprazole discontinuation, the cough resolved. DISCUSSION: The most common causes of chronic cough in nonsmokers of all ages are postnasal drip syndrome, asthma, and GERD. However, persistent cough without bronchospasm or other pulmonary involvement may occur as a drug adverse effect. According to the US omeprazole package insert, cough is observed as an adverse reaction in 1.1% of patients, although this has not been mentioned in international drug information sources or medical literature. A MEDLINE search (1966–June 2003) using the terms cough, drug related, adverse effects, and omeprazole failed to find any data. In our patient, there was a temporal relationship between cough and medication use, suggesting a causal relationship. An objective causality assessment revealed that the adverse drug reaction was probable. The mechanism is unclear. CONCLUSIONS: Chronic, persistent cough may occur as an adverse effect of omeprazole therapy. Clinicians must be aware of this adverse effect to avoid useless and costly tests.


2020 ◽  
pp. S35-S42
Author(s):  
M. Lucanska ◽  
A. Hajtman ◽  
V. Calkovsky ◽  
P. Kunc ◽  
R. Pecova

Cough is one of the most important defensive reflexes. However, extensive non- productive cough is a harmful mechanism leading to the damage of human airways. Cough is initiated by activation of vagal afferents in the airways. The site of their convergence is particularly the nucleus of the solitary tract (nTS). The second-order neurons terminate in the pons, medulla and spinal cord and there is also the cortical and subcortical control of coughing. Upper airway cough syndrome (UACS) – previously postnasal drip syndrome - is one of the most common causes of chronic cough together with asthma and gastroesophageal reflux. The main mechanisms leading to cough in patients with nasal and sinus diseases are postnasal drip, direct irritation of nasal mucosa, inflammation in the lower airways, upper airway inflammation and the cough reflex sensitization. The cough demonstrated by UACS patients is probably due to hypersensitivity of the upper airways sensory nerve or lower airways sensory nerve, or a combination of both. Further studies are needed to clarify this mechanism.


2005 ◽  
Vol 114 (4) ◽  
pp. 253-257 ◽  
Author(s):  
Bryant Lee ◽  
Peak Woo

Chronic cough is often attributed to reflux, postnasal drip, or asthma. We present 28 patients who had chronic cough or throat-clearing as a manifestation of sensory neuropathy involving the superior or recurrent laryngeal nerve. They had been identified as having sudden-onset cough, laryngospasm, or throat-clearing after viral illness, surgery, or an unknown trigger. Cough and laryngospasm were the most common complaints. Seventy-one percent of the patients had concomitant superior laryngeal nerve or recurrent laryngeal nerve motor neuropathy documented by laryngeal electromyography or videostroboscopy. After a negative workup for reflux, asthma, or postnasal drip, these patients were treated with gabapentin at 100 to 900 mg/d. Symptomatic relief was achieved in 68% of the patients. Sensory neuropathy of the recurrent laryngeal nerve or superior laryngeal nerve should be considered in the workup for chronic cough or larynx irritability. Symptomatic management of patients with cough and laryngospasm due to a suspected sensory neuropathy may include the use of antiseizure medications such as gabapentin.


2019 ◽  
Vol 87 (2) ◽  
pp. 77-80 ◽  
Author(s):  
Stefania De Simone ◽  
Francesca Maglietta ◽  
Michela Ferrara ◽  
Lorenzo Spagnolo ◽  
Pietrantonio Ricci ◽  
...  

Crime scene investigation should be carried out using a critical forensic approach by an expert team. This provides essential tools in the research and collection of evidence and samples which must be integrated with the autopsy and the police officers’ investigations. This paper aims to highlight the importance of a multidisciplinary approach to crime scene investigation and describes a very interesting criminal case. As demonstrated by this case, the evidence obtained from the crime scene analysis sheds light on difficult cases, such as murders staged as suicides or accidents.


2012 ◽  
Vol 126 (5) ◽  
pp. 441-444 ◽  
Author(s):  
R S Natt ◽  
J E Earis ◽  
A C Swift

AbstractBackground and methods:Chronic cough is defined as a cough persisting for more than eight weeks. This condition generates significant healthcare and economic costs. It is associated with a spectrum of disorders across multiple medical specialties and can provide significant challenges for effective evaluation and management. The current literature was reviewed to gain further insight into chronic cough, including its relationship with sinonasal disease.Results:Within the reviewed literature, there was strong emphasis on post-nasal drip syndrome as a major causative factor.Conclusion:Cough is the most common complaint for which adult patients seek medical consultation in primary care settings. Chronic cough is associated with a deterioration in the quality of patients' lives. Thorough assessment of a patient with a chronic cough relies on a multidisciplinary approach.


2014 ◽  
Vol 23 (3) ◽  
pp. 106-115
Author(s):  
Swapna Chandran

Aspiration and pharyngeal dysphagia occur across various age groups as a result of numerous conditions, such as neurological, oncological, or inflammatory processes. After nonsurgical techniques fail, surgical options for treatment of the larynx or cricopharygeus muscle are considered. The most common causes of laryngeal causes of dysphasia/aspiration can be treated with procedures aimed at closing the laryngeal gap resulting from paralysis. Cricopharyngeal dysfunction often can be identified by various diagnostic modalities, but dilation, botulinum toxin, and myotomy are commonly employed management options.


2015 ◽  
Vol 79 (5) ◽  
pp. 749-752 ◽  
Author(s):  
Melanie Greifer ◽  
Maria T. Santiago ◽  
Kalliope Tsirilakis ◽  
Jeffrey C. Cheng ◽  
Lee P. Smith

CHEST Journal ◽  
2006 ◽  
Vol 129 (1) ◽  
pp. 59S-62S ◽  
Author(s):  
Melvin R. Pratter
Keyword(s):  

Author(s):  
Katie Scott

A chronic cough in children is defined in the British Thoracic Society guidelines as a cough of 8 weeks or more. The aetiology of a chronic cough in children differs from adult populations, due to decreased cough reflex control in children, differences in airway anatomy and physiology, and immunological and neurological maturation changes. The three most common causes of chronic cough in adults (asthma, gastro-oesophageal reflux, and upper airway cough syndrome) account for less than 10% of the causes in children. Thus, it is important to assess and manage chronic cough in children differently.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jan Domaradzki ◽  
Dariusz Walkowiak

Caring for patients suffering from a rare disease (RD) requires the special and combined efforts of different healthcare professionals, including nurses, physiotherapists and physicians. Nevertheless, Poland still lacks a national plan for RDs and the undergraduate and postgraduate education of future healthcare professionals on RDs is also inadequate. Thus, the aim of this study was to assess the awareness of RDs among nursing, physiotherapy and medical students in Poland. It shows that although 98% of respondents had heard of the term “rare disease,” most students had problems in defining the most common causes of RDs and their prevalence. Students also lacked basic knowledge about the healthcare system for RD patients in the country. While over 95% of future nurses, physiotherapists and physicians assessed their knowledge about RDs as insufficient or very poor, almost 92% of medical students, and 84% of physiotherapy and nursing students, did not feel prepared for caring for RD patients. Furthermore, although the vast majority of respondents declared eagerness to broaden their knowledge on RDs, only 45% of medical students, 76% of nursing students and 88% of physiotherapy students believed that RDs should be included into the medical curricula. Simultaneously, for most students the Internet was the prime source of information on RDs. It is concluded that as caring for RD patients requires a multidisciplinary approach, by identifying the gap in the education of future nurses, physiotherapists and physicians this study shows that there is an urgent need of better education about RDs among future healthcare professionals.


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