scholarly journals Cornual Polyps of the Fallopian Tube Are Associated with Endometriosis and Anovulation

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
S. A. AlAsiri ◽  
M. Ghahremani ◽  
P. F. McComb
Keyword(s):  
Fallopian Tube ◽  
Case Series ◽  
Infertile Women ◽  
The Relationship

Background. The relationship between tubal cornual polyps and endometriosis and ovulatory disorders in infertile women is unclear. Our objective was to determine such an association from our database and review the literature.Methods. Twenty-two infertile women with tubal cornual polyps were assessed for coexistence of oligoovulation/anovulation and endometriosis with stratification for polyp diameter (large: ≥5 mm diameter, small <5 mm diameter).Result(s). Oligoovulation/anovulation was more prevalent in women with large versus small tubal cornual polyps (P=0.0048). Endometriosis was associated with both large and small polyps.Conclusion(s). This case series confirms the association of tubal cornual polyps with oligoovulation/anovulation and endometriosis in infertile women. This case series is limited by a lack of controls.

scholarly journals The Relationships Between Serum DHEA-S and AMH Levels in Infertile Women: A Retrospective Cross-Sectional Study

2021 ◽  
Vol 10 (6) ◽  
pp. 1211
Author(s):  
Li-Te Lin ◽  
Kuan-Hao Tsui
Keyword(s):  
Generalized Linear Models ◽  
Large Scale ◽  
Linear Models ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Dehydroepiandrosterone Sulphate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Infertile Women ◽  
The Relationship

The relationship between serum dehydroepiandrosterone sulphate (DHEA-S) and anti-Mullerian hormone (AMH) levels has not been fully established. Therefore, we performed a large-scale cross-sectional study to investigate the association between serum DHEA-S and AMH levels. The study included a total of 2155 infertile women aged 20 to 46 years who were divided into four quartile groups (Q1 to Q4) based on serum DHEA-S levels. We found that there was a weak positive association between serum DHEA-S and AMH levels in infertile women (r = 0.190, p < 0.001). After adjusting for potential confounders, serum DHEA-S levels positively correlated with serum AMH levels in infertile women (β = 0.103, p < 0.001). Infertile women in the highest DHEA-S quartile category (Q4) showed significantly higher serum AMH levels (p < 0.001) compared with women in the lowest DHEA-S quartile category (Q1). The serum AMH levels significantly increased across increasing DHEA-S quartile categories in infertile women (p = 0.014) using generalized linear models after adjustment for potential confounders. Our data show that serum DHEA-S levels are positively associated with serum AMH levels.

scholarly journals Association of psychiatric comorbidities with the risk of transport accidents in ADHD and MPH

2021 ◽  
Vol 30 ◽  
Author(s):  
Yi-Chun Liu ◽  
Vincent Chin-Hung Chen ◽  
Yao-Hsu Yang ◽  
Yi-Lung Chen ◽  
Michael Gossop
Keyword(s):  
Dose Response ◽  
Case Series ◽  
Autism Spectrum ◽  
Research Database ◽  
Accident Risk ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Series Analysis ◽  
The Relationship ◽  
Transport Accidents

Abstract Aims Although the relationship between attention-deficit/hyperactivity disorder (ADHD) and transport accidents has been shown, there is limited information on the relationship between medication and dose–response effects and transport accident risk. This study aims to determine whether young people with ADHD, including adolescents, are more prone to transport accidents than those without, and the extent to which methylphenidate (MPH) prescription in these patients reduces the risk. Methods We identified 114 486 patients diagnosed with ADHD from Taiwan's National Health Insurance Research Database from 1997 to 2013. Using a Cox regression model, we compared the risk of transport accidents between ADHD and non-ADHD groups and estimated the effect of MPH on accidents. Furthermore, we applied a self-control case-series analysis to compare the risk of accidents during the medication periods with the same patients' non-medication periods. Results Male ADHD patients had a higher risk of transport accidents than non-ADHD individuals (adjusted hazard ratio [aHR] = 1.24, [95% confidence interval (CI) 1.10–1.39]), especially for those comorbid with epilepsy, oppositional defiant disorder/conduct disorder (ODD/CD), and intellectual disabilities (ID). Female ADHD patients showed no relationship, except for comorbid with autism spectrum disorder (ASD) or ID. We found a reduced risk of transport accidents in patients with ADHD with MPH medication than those without MPH, with a plausible dose–response relationship (aHR of 0.23 to 0.07). A similar pattern was found in self-controlled case-series analysis. Conclusions Male patients with ADHD, especially those comorbid with epilepsy, ODD/CD, or ID, were at high risk of transport accidents. Female patients, when comorbid with ASD or ID, also exhibited a higher risk of accidents. MPH treatment lowered the accident risk with a dose–response relationship.

A Cry for Help: Exploring the Relationship between Perceived Social Support and Quality of Life in Infertile Women of South India

2021 ◽  
Vol 23 (23) ◽  
Author(s):  
Siddharth R ◽  
Dr. Nisha B ◽  
Dr. Timsi Jain ◽  
Dr. Anantha Eashwar ◽  
Dr Ruma Dutta
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
South India ◽  
Perceived Social Support ◽  
Infertile Women ◽  
Cry For Help ◽  
The Relationship

scholarly journals Role of IgG Chlamydia antibody in tubal factor infertility

2017 ◽  
Vol 6 (3) ◽  
pp. 837
Author(s):  
Sheila Balakrishnan ◽  
Anitha Malathi ◽  
Geetha Raveendran ◽  
Dolly Johnrose ◽  
Sreekumari Radha
Keyword(s):  
Chlamydial Infection ◽  
Venous Blood ◽  
Igg Antibody ◽  
Infertile Women ◽  
Tubal Factor Infertility ◽  
Tubal Factor ◽  
Tubal Disease ◽  
The Difference ◽  
Chlamydial Antibody ◽  
The Relationship

Background: Chlamydial infection is considered to be one of the important causes of tubal factor infertility. This study will help to explore the relationship between positive Chlamydial infection and tubal damage in infertile women assessed by diagnostic laparoscopy. The results will help to determine whether a policy of routine screening for Chlamydia antibody is justifiable in infertile women to suspect tubal factor so that they can be taken up for laparoscopy earlier.Methods: A prospective study was performed on 158 consecutive patients who underwent laparoscopy as part of infertility evaluation. About 5 mL of venous blood was drawn preoperatively to detect Chlamydia IgG antibody in all the patients by ELISA. The laparoscopic findings were documented and the relationship to Chlamydial antibody evaluated.Results: Of the 158 patients who underwent laparoscopy, 95 patients had evidence of tubal disease as evidenced by unilateral or bilateral tubal block, peritubal adhesions, hydrosalpinx, beading of the tube and unhealthy shaggy appearance. Of the 95 patients with documented tubal disease at laparoscopy, 14 (14.7%) had antibodies to Chlamydia. Of the 63 patients with normal tubes, 12 (19%) had Chlamydial positivity. The difference is not statistically significant. However of the 26 patients who were positive for Chlamydia antibodies 14 patients (53.8%) had abnormal tubes. Out of the 158 patients who underwent laparoscopy 26 patients were positive for Chlamydia. Hence the prevalence in our study is 16.4% (26/158). The sensitivity is 14.7% and the specificity is 81%.Conclusions: This study showed no difference in Chlamydial positivity between infertile women with abnormal tubes and those with normal looking tubes in our population. The absence of Chlamydial antibodies cannot be taken as a marker for normal tubes. Hence screening for chlamydial antibody can neither be used as a screening test for tubal factor infertility nor to decide on the need for laparoscopy in the present population.

scholarly journals Synergism of Hypothyroidism and Hyperprolactinemia to impact on efficiency of menstrual cycle and ovulatory status

2017 ◽  
Vol 1 (28) ◽  
pp. 661-670
Author(s):  
NASSER NAFAA ABRAHEM ◽  
SAAD HASSAN DREIJ ◽  
Mahdi Saber Al-Deresawi
Keyword(s):  
Thyroid Hormone ◽  
Menstrual Cycle ◽  
Teaching Hospital ◽  
Infertile Women ◽  
Menstrual Disturbance ◽  
Menstrual Irregularities ◽  
Relationship Of ◽  
The Relationship ◽  
Hormonal Assay

This study aimed to determine the relationship of  thyroid hormone disturbance and prolactin over production to impact on the menstrual irregularities anovulation .This  study were carried out in Al-Karama teaching hospital and  included (47) primary infertile women, (30 ) of them were with hypothyroidism , the patients aged between (18-40). This study extended from February to June  2017. The hormonal assay of TSH, FT3, FT4 ,FSH , LH and PRL that revealed  :- There were high  significantly (p < 0.01) increased in TSH concentrations , significantly (p < 0.05) decreased in levels of FT3 and  FT4.Gonadotropins hormones recorded significantly ( p <0.05) decreased in levels of FSH and non significantly increased in levels of LH. Prolactin concentrations that obtained revealed to significantly (p < 0.05) increased in patients with hypothyroidism . This study reported there were (70%) of hypothyroidism patients with menstrual disturbance. We concluded , that hypothyroidism and Hyperprolactinemia commonly related and synergized to menstrual irregularities and ovulatory failure. 

scholarly journals Evaluation of tubal and peritoneal factors in chlamydia positive infertile women by laparoscope

2017 ◽  
Vol 7 (2) ◽  
pp. 54-58
Author(s):  
Nurjahan Begum ◽  
Fawzia Hussain ◽  
Farzana Deeba ◽  
Shaheen Ara Anwary ◽  
Parveen Sultana ◽  
...  
Keyword(s):  
Fallopian Tubes ◽  
Test Results ◽  
Immunofluorescence Test ◽  
Common Cause ◽  
Positive Group ◽  
Chlamydia Trachomatis Infection ◽  
Infertile Women ◽  
Antibody Titres ◽  
The Difference ◽  
The Relationship

Background: Abnormalities or damage to the fallopian tube interferes with fertility and is responsible for abnormal implantation (eg, ectopic pregnancy). Obstruction of the distal end of the fallopian tubes results in accumulation of the normally secreted tubal fluid, creating distention of the tube with subsequent damage of the epithelial cilia (hydrosalpinx). Genital Chlamydia trachomatis infection has a worldwide distribution6 and is now recognized as the single most common cause of tubal peritoneal damage. The study explores the relationship between serum chlamydia antibody titres (CATs) and detection of tubal damage in infertile women.Objective: To Evaluation of tubal and peritonial factors in chlamydia positive infertile women by laparoscope.Methodology: The tubal status and pelvic findings in 138 women underwent laparoscopy for infertility were related to CAT, which was measured using the whole-cell inclusion immunofluorescence test. RESULTS: A total of 138 infertile women who underwent laparoscopic investigation for infertility were identified and they were divided in two groups, on the bsis of presence is absence Chlamydia positive (n=69) and Chlamydia Negative (n=69). Demographic status were almost similar between two groups, however service holder was found significantly higher in Chlamydia positive group (17 vs. 7). Tubal block was found in 44(63.7%) in Chlamydia positive and 37(53.6%) in Chlamydia negative. The difference was statistically significant (p<0.01) between two groups. Site of block & hydrosalpinges was almost similar between two groups. POD was completely obliterated in 10(14.5%) in Chlamydia positive and 3(4.3%) in Chlamydia negative. The difference was statistically significant (p<0.05) between two groups.Conclusion: Chlamydia serology is useful mainly as a screening test for the likelihood of tubal damage in infertile women and may facilitate decisions on which women should proceed with further investigations without delay.J Shaheed Suhrawardy Med Coll, December 2015, Vol.7(2); 54-58

scholarly journals The Relationship Between Gait Symmetry and Metabolic Demand in Individuals With Unilateral Transfemoral Amputation: A Preliminary Study

2019 ◽  
Vol 184 (7-8) ◽  
pp. e281-e287
Author(s):  
Caitlin E Mahon ◽  
Benjamin J Darter ◽  
Christopher L Dearth ◽  
Brad D Hendershot
Keyword(s):  
Energy Expenditure ◽  
Case Series ◽  
Step Length ◽  
Metabolic Energy ◽  
Metabolic Power ◽  
Transfemoral Amputation ◽  
Preliminary Study ◽  
Spatial Asymmetries ◽  
Metabolic Energy Expenditure ◽  
The Relationship

Abstract Introduction Temporal-spatial symmetry allows for optimal metabolic economy in unimpaired human gait. The gait of individuals with unilateral transfemoral amputation is characterized by temporal-spatial asymmetries and greater metabolic energy expenditure. The objective of this study was to determine whether temporal-spatial asymmetries account for greater metabolic energy expenditure in individuals with unilateral transfemoral amputation. Materials and Methods The relationship between temporal-spatial gait asymmetry and metabolic economy (metabolic power normalized by walking speed) was retrospectively examined in eighteen individuals with transfemoral amputation walking at a self-selected velocity overground. Pearson’s product-moment correlations were used to assess the relationship between: (1) step time symmetry and metabolic economy and (2) step length symmetry and metabolic economy. The retrospective analysis of this data was approved by the Walter Reed National Military Medical Center Institutional Review Board and all individuals provided written consent. Additional insights on this relationship are presented through a case series describing the temporal-spatial and metabolic responses of two individuals with transfemoral amputation who completed a split-belt treadmill walking test. Results For the cohort of individuals, there was no significant relationship between metabolic economy and either step time asymmetry or step length asymmetry. However, the case series showed a positive relationship between step length asymmetry and metabolic power as participants adapted to split-belt treadmill walking. Conclusion There is mixed evidence for the relationship between temporal-spatial asymmetries and metabolic energy expenditure. This preliminary study may suggest optimal metabolic energy expenditure in individuals with transfemoral amputation occurs at an individualized level of symmetry and resultant deviations incur a metabolic penalty. The results of this study support the idea that addressing only temporal-spatial gait asymmetries in individuals with transfemoral amputation through rehabilitation may not improve metabolic economy. Nevertheless, future prospective research is necessary to confirm these results and implications for clinical practice.

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