scholarly journals Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Francesca Salvatori ◽  
Saverio Siciliano ◽  
Francesco Maione ◽  
Dario Esposito ◽  
Stefania Masone ◽  
...  
Keyword(s):  
Colonic Mucosa ◽  
Current Data ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
High Resolution Imaging ◽  
Bowel Diseases ◽  
Surveillance Programs ◽  
Risk Patients ◽  
Resolution Imaging ◽  
Inflammatory Bowel

Confocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed “virtual biopsy” as they simulate the images seen in traditional histology. Recently, the use of CLE was reported in the study of colonic mucosa in patients with inflammatory bowel diseases and in particular in patients affected by ulcerative colitis. CLE has the potential to have an important role in management of IBD patients as it can be used to assess the grading of colitis and in detection of microscopic colitis in endoscopically silent segments. Moreover, CLE can be used in surveillance programs especially in high-risk patients. This report aims to evaluate the current data on the application of confocal endomicroscopy in clinical gastroenterology and particularly in the study of colonic mucosa in UC patients.

scholarly journals Quantitative assessment of mucosal architecture using computer-based analysis of confocal laser endomicroscopy in inflammatory bowel diseases

2019 ◽  
Vol 89 (3) ◽  
pp. 626-636 ◽  
Author(s):  
Lucille Quénéhervé ◽  
Grégoire David ◽  
Arnaud Bourreille ◽  
Jean Benoît Hardouin ◽  
Gabriel Rahmi ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Quantitative Assessment ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Bowel Diseases ◽  
Computer Based ◽  
Inflammatory Bowel

scholarly journals Advanced Endoscopic Imaging Techniques for the Study of Colonic Mucosa in Patients with Inflammatory Bowel Disease

2016 ◽  
Vol 54 (1) ◽  
pp. 11-23
Author(s):  
Daniela Ştefănescu ◽  
S.P. Pereira ◽  
M.M. Filip ◽  
A. Săftoiu ◽  
S. Cazacu
Keyword(s):  
Colonic Mucosa ◽  
Narrow Band Imaging ◽  
Imaging Techniques ◽  
Mucosal Healing ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Autofluorescence Imaging ◽  
Endoscopic Techniques ◽  
White Light Endoscopy ◽  
Inflammatory Bowel

Background. Crohn’s disease and ulcerative colitis are inflammatory bowel diseases (IBD) associated with colorectal cancer risk in long-standing diseases. In order to assess the colonic mucosa and to discover dysplastic or neoplastic lesions, advanced endoscopic techniques are needed. Such techniques are detailed in this review: chromoendoscopy, autofluorescence imaging (AFI), narrow band imaging (NBI), i-SCAN, Fujinon Intelligent Color Enhancement (FICE) and confocal laser endomicroscopy (CLE). Aim. The aim of the review is to describe and establish the clinical impact of advanced endoscopic techniques, that could be used in IBD patients’examination in order to assess mucosal healing, microscopic inflammation, dysplasia or neoplasia. Materials and Methods. A literature research about new endoscopic approaches of patients with IBD was made. Results. A lot of studies have been performed to reveal which imaging technique might be used for IBD surveillance. Regarding dysplasia or neoplasia detection and mucosal healing or inflammation assessment, CE proved to be superior to white light endoscopy (WLE), while NBI and AFI did not show an encouraging result. I-SCAN did not improve the colonoscopy quality while FICE has been used in a few studies. CLE could be used to characterize a lesion, providing the same results as conventional histology. Conclusion. At the moment, CE is the only technique which has been included in guidelines for IBD surveillance. CLE can be used to assess any lesion detected with WLE during surveillance, while the other imaging techniques require more studies to determine their efficacy or inefficacy.

W1266 Confocal Laser Endomicroscopy (CLE) Reveals Mucosal Accumulation of Plga-Nanoparticles in Ulcerous Lesions of Patients With Inflammatory Bowel Diseases

2010 ◽  
Vol 138 (5) ◽  
pp. S-687 ◽  
Author(s):  
Carsten Schmidt ◽  
Eva M. Collnot ◽  
Christian Bojarski ◽  
Michael Schumann ◽  
Joerg D. Schulzke ◽  
...  
Keyword(s):  
Inflammatory Bowel Diseases ◽  
Plga Nanoparticles ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Bowel Diseases ◽  
Inflammatory Bowel
Sign in / Sign up

Export Citation Format

Share Document