scholarly journals Bone Mineral Density in Spinal Cord Injury: An Evaluation of the Distal Femur

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Alexandra Passos Gaspar ◽  
Marise Lazaretti-Castro ◽  
Cynthia M. A. Brandão
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mineral ◽  
Distal Femur ◽  
Secondary Process ◽  
Control Group ◽  
Mineral Density ◽  
X Ray ◽  
Cord Injury

Osteoporosis (OP) in spinal cord injury (SCI) patients is a secondary process in which numerous factors are involved. Diagnosing OP and the threshold for fractures in this population, based on bone mineral density (BMD) measured by double energy X-ray absorptiometry (DXA), is still a challenge. The aim of this study was to evaluate bone mineral loss by DXA, its relationship with body composition and fracture incidence, in complete paraplegics patients, compared with aged-matched controls; we include a nonstandard bone site, the distal femur, and describe the technical and practical aspects of this procedure. Twenty-five SCI patients were included in the study and 17 subjects as control group. No prior or recent fractures were observed in X-ray analysis. The BMD of all femoral sites was significantly lower in patients than in controls (femoral neck, total femur, and distal femur); no difference was observed between BMD of the lumbar spine of patients and controls. We found inverse relationship between time of SCI and bone mineral mass only for distal femur BMD. We conclude that the distal femur is a more sensitive bone site for assessing bone loss by DXA, in SCI patients, than the proximal femoral sites.

scholarly journals Dual-energy X-ray absorptiometry overestimates bone mineral density of the lumbar spine in persons with spinal cord injury

Spinal Cord ◽  
2009 ◽  
Vol 47 (8) ◽  
pp. 628-633 ◽  
Author(s):  
W A Bauman ◽  
E Schwartz ◽  
I S Y Song ◽  
S Kirshblum ◽  
C Cirnigliaro ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Dual Energy ◽  
Mineral Density ◽  
X Ray ◽  
Cord Injury

scholarly journals Relationships between T-scores at the hip and bone mineral density at the distal femur and proximal tibia in persons with spinal cord injury

2019 ◽  
Vol 43 (5) ◽  
pp. 685-695 ◽  
Author(s):  
Christopher M. Cirnigliaro ◽  
J. Scott Parrott ◽  
Mary Jane Myslinski ◽  
Pierre Asselin ◽  
Alexander T. Lombard ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mineral ◽  
Distal Femur ◽  
Proximal Tibia ◽  
Mineral Density ◽  
Cord Injury

scholarly journals Bone Mineral Density at the Distal Femur and Proximal Tibia and Related Factors During the First Year of Spinal Cord Injury

2021 ◽  
Vol Volume 14 ◽  
pp. 1121-1129
Author(s):  
Xin Zheng ◽  
Yanyan Qi ◽  
Hongjun Zhou ◽  
Haiqiong Kang ◽  
Yanming Tong ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mineral ◽  
Distal Femur ◽  
Proximal Tibia ◽  
First Year ◽  
Mineral Density ◽  
Related Factors ◽  
Cord Injury

Changes in Osteoprotegerin/RANKL System, Bone Mineral Density, and Bone Biochemicals Markers in Patients with Recent Spinal Cord Injury

2005 ◽  
Vol 76 (6) ◽  
pp. 404-411 ◽  
Author(s):  
L. Maïmoun ◽  
I. Couret ◽  
D. Mariano-Goulart ◽  
A. M. Dupuy ◽  
J.-P. Micallef ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Mineral ◽  
Mineral Density ◽  
Cord Injury

Acupuncture for Treatment of Secondary Osteoporosis in Patients with Spinal Cord Injury: A Controlled Study

2014 ◽  
Vol 32 (5) ◽  
pp. 381-386 ◽  
Author(s):  
Qingxi Meng ◽  
Xin Liu ◽  
Qunqun Shan ◽  
Peng Yu ◽  
Zhaohu Mao ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Combination Therapy ◽  
Bone Mineral ◽  
Secondary Osteoporosis ◽  
Mineral Density ◽  
Cord Injury ◽  
Group 2 ◽  
Group 1

Objective We explored the effect of adjunctive acupuncture on secondary osteoporosis in patients with spinal cord injury (SCI). Methods Patients with subacute SCI were recruited and divided into two groups by patient choice: group 1 patients received standard combination therapy and group 2 patients received combination therapy plus acupuncture for 3 months. The concentrations of IgG, IgM and tumour necrosis factor α (TNFα) in serum and the bone mineral density were measured before and after treatment. Result The decrease in the concentration of TNFα and IgM in patients in group 2 compared with those in group 1 was statistically significant. The IgG level showed no significant change in either group. Bone mineral density increased more after adjunctive acupuncture, but the difference was not significant. Conclusions Further research is needed to determine whether acupuncture as an adjunct to combination therapy can reduce osteoporosis in patients with subacute SCI. Trial Registration Number P153-2008-36

scholarly journals Spinal Cord Injury Induced Osteoporosis: Case Report and Current Literature

2021 ◽  
Vol 9 (2) ◽  
pp. 155-159
Author(s):  
Abdulai Bangura ◽  
Thomas Shuler ◽  
Lisa Wright ◽  
Anne Lake
Keyword(s):  
Bone Mineral Density ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Bone Loss ◽  
Bone Mineral ◽  
Treatment Plan ◽  
Treatment Options ◽  
Definitive Treatment ◽  
Mineral Density ◽  
Cord Injury

Background: Among the various etiologies of osteoporosis, spinal cord injury has a drastic progression of the disease, causing weekly bone loss. There is no definitive treatment for the prevention of osteoporosis in these individuals. This review illustrates the recent findings on the pathophysiology, treatment, and management of spinal cord injury-induced osteoporosis. Furthermore, we cover a case of a male patient who experienced severe bone loss after a spinal cord injury at the age of 21 years. The Case: We have a 57-year-old man with a history of AIS grade A spinal cord injury, level T11 with rod fixation from a motorcycle collision at age 21. His fracture history following the injury includes tibia, femur, and vertebral fractures. Bone mineral density imaging revealed notable T-scores ranging from -3.1 to -3.4 at the hip and femurs. Treatment plan consisted of teriparatide, dietary supplements, and physical therapy. Biomarkers from baseline to post one month of treatment revealed the following: procollagen type 1 N-terminal propeptide from 38 mcg/L to 70 mcg/L and C-terminal telopeptide from 209 pg/mL to 88 pg/mL, representing an increased bone formation and decreased bone resorption, respectively. After two years, bone mineral density T-scores improved to -2.7 on the left and the patient was capable of standing for the first time with the assistance of a standing frame. Conclusion: Our case exemplified the progression of the disease and treatment options. A basis for the derivation of future innovative therapies has been covered. Favorable treatments and management are described in the review.

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