scholarly journals Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Jatin M. Vyas ◽  
Wayne A. Marasco
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Marrow Transplantation ◽  
Marrow Transplant ◽  
Allogeneic Bone ◽  
Transplant Patients ◽  
Liver Functions ◽  
Extensive Necrosis

We report two cases of fatal hepatic failure in patients who received matched unrelated bone marrow transplantation. Both patients presented with high fevers, abnormal liver functions tests, and hypodense lesions in the liver by CT scan. Histologic examination of postmortem liver samples demonstrated extensive necrosis, and immunohistochemistry was positive for adenovirus.

Outbreak ofStenotrophomonas maltophiliaBacteremia Among Patients Undergoing Bone Marrow Transplantation: Association With Faulty Replacement of Handwashing Soap

1999 ◽  
Vol 20 (11) ◽  
pp. 756-758 ◽  
Author(s):  
Jeffrey D. Klausner ◽  
Carol Zukerman ◽  
Ajit P. Limaye ◽  
Lawrence Corey
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Healthcare Worker ◽  
Molecular Typing ◽  
Marrow Transplantation ◽  
Stenotrophomonas Maltophilia ◽  
Marrow Transplant ◽  
Hand Washing ◽  
Transplant Patients ◽  
Typing Methods

AbstractUsing molecular typing methods, we confirmed an outbreak ofStenotrophomonas maltophiliaamong bone marrow transplant patients. The likely source was a healthcare worker who may have washed with moisturizer instead of soap between patients. Hospital epidemiologists need to go beyond antibiograms when evaluating outbreaks and be vigilant about all aspects of hand washing.

scholarly journals Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major

2017 ◽  
Vol 1 (25) ◽  
pp. 2421-2432 ◽  
Author(s):  
Yongliang Huo ◽  
Jonathan R. Lockhart ◽  
Shanrun Liu ◽  
Suean Fontenard ◽  
Mike Berlett ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Bone Marrow Transplant ◽  
Marrow Transplantation ◽  
Globin Gene ◽  
Thalassemia Major ◽  
Marrow Transplant ◽  
Allogeneic Bone ◽  
Key Points ◽  
Gene Switch

Key Points After completion of the fetal-to-adult globin gene switch, humanized β-thalassemia major mice are transfusion dependent. Perinatal humanized β-thalassemia major mice are rescued by bone marrow transplantation in the absence of cytoreductive conditioning.

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