scholarly journals Pattern and Risk Factors of Central Compartment Lymph Node Metastasis in Papillary Thyroid Cancer: A Prospective Study from an Endocrine Surgery Centre

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Sudhi Agarwal ◽  
Gyan Chand ◽  
Sushila Jaiswal ◽  
Anjali Mishra ◽  
Gaurav Agarwal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Tumour Size ◽  
Central Compartment ◽  
Papillary Thyroid ◽  
Lymph Nodes Metastasis ◽  
Lymph Nodes Dissection ◽  
A Prospective Study

Lymphatic metastasis in papillary thyroid cancer (PTC) is eminent; however, the extent of central compartment lymph nodes dissection (CCD) is controversial and requires the knowledge of pattern and risk factors for central compartment lymph nodes metastasis (CCM). We did a prospective study of 47 cases with PTC who underwent total thyroidectomy (TT) with CCD with/without lateral lymph nodes dissection (LND). Clinicopathological profile including CCM as ipsilateral and contralateral was documented. On histopathology, the mean tumour size was3.57±2.42 cm 59.6% had CCM, which was bilateral in the majority (60.72%). The tumour-size was the most important predictor for lymph nodes metastasis-(P=0.018) whereas multicentricity-(P=0.002) and ipsilateral CCM-(P=0.001) were the predictors for contralateral CCM. The long-term morbidity of CCD done in primary setting is comparable with TT-alone. Bilateral CCD should be done with thyroidectomy in PTC, otherwise the risk of residual diseases and subsequent recurrence is high. The long-term morbidity is comparable in experienced hands.

QUANTITATIVE AND QUALITATIVE CHARACTERISTICS OF METASTASES IN REGIONAL LYMPH NODES - RISK FACTORS FOR THE RECURRENCE OF PAPILLARY THYROID CANCER IN CHILDREN AND ADOLESCENTS

2018 ◽  
Vol 64 (2) ◽  
pp. 159-165
Author(s):  
Mikhail Fridman ◽  
Svetlana Mankovskaya ◽  
Olga Krasko
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Children And Adolescents ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Regional Lymph Nodes ◽  
Cancer In Children ◽  
Qualitative Characteristics

Among the factors determining the relapse/persistence of papillary thyroid cancer in children and adolescents the most important are the age of the patient (p= 0.003), the presence of concomitant background pathology (p

scholarly journals The association between tumor’s location and cervical lymph nodes metastasis in papillary thyroid cancer

Gland Surgery ◽  
2019 ◽  
Vol 8 (5) ◽  
pp. 557-568 ◽  
Author(s):  
Ting-Ting Zhang ◽  
Xiu-Zhu Qi ◽  
Jian-Ping Chen ◽  
Rong-Liang Shi ◽  
Shi-Shuai Wen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Cervical Lymph Nodes ◽  
Lymph Nodes Metastasis

scholarly journals Axillary lymph nodes metastasis in a patient with recurrent papillary thyroid cancer: a case report

2015 ◽  
Vol 9 (1) ◽  
Author(s):  
Mohamed T. Hafez ◽  
Basel Refky ◽  
Khaled Abd Elwahab ◽  
Mohammad Arafa ◽  
Islam Abdou ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Case Report ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Papillary Thyroid ◽  
Lymph Nodes Metastasis

Metastasis of Right Upper Para-Esophageal Lymph Nodes in Central Compartment Lymph Node Dissection of Papillary Thyroid Cancer

2009 ◽  
Vol 33 (10) ◽  
pp. 2094-2098 ◽  
Author(s):  
Byung-Joo Lee ◽  
Jin-Choon Lee ◽  
Soo-Geun Wang ◽  
Yong-Ki Kim ◽  
In-Ju Kim ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Lymph Node Dissection ◽  
Central Compartment ◽  
Papillary Thyroid ◽  
Node Dissection

Preoperative High-Resolution Ultrasound for the Assessment of Malignant Central Compartment Lymph Nodes in Papillary Thyroid Cancer

Thyroid ◽  
2015 ◽  
Vol 25 (12) ◽  
pp. 1351-1354 ◽  
Author(s):  
Mamoona T. Khokhar ◽  
Kristopher M. Day ◽  
Rohit B. Sangal ◽  
Nigar N. Ahmedli ◽  
Latha R. Pisharodi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
High Resolution ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Central Compartment ◽  
Papillary Thyroid

scholarly journals Risk factors of permanent hypoparathyroidism after total thyroidectomy and central neck dissection for papillary thyroid cancer: a prospective study

2020 ◽  
Vol 71 (2) ◽  
pp. 126-133
Author(s):  
Paulina Godlewska ◽  
Małgorzata Benke ◽  
Elżbieta Stachlewska-Nasfeter ◽  
Jacek Gałczyński ◽  
Bartosz Puła ◽  
...  
Keyword(s):  
Risk Factors ◽  
Thyroid Cancer ◽  
Prospective Study ◽  
Total Thyroidectomy ◽  
Neck Dissection ◽  
Central Neck Dissection ◽  
Central Neck ◽  
Permanent Hypoparathyroidism ◽  
Papillary Thyroid ◽  
A Prospective Study

scholarly journals Long-Term Efficacy of Lymph Node Reoperation for Persistent Papillary Thyroid Cancer

2010 ◽  
Vol 95 (5) ◽  
pp. 2187-2194 ◽  
Author(s):  
Osama Al-Saif ◽  
William B. Farrar ◽  
Mark Bloomston ◽  
Kyle Porter ◽  
Matthew D. Ringel ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Papillary Thyroid Cancer ◽  
Surgical Resection ◽  
Papillary Thyroid ◽  
Cervical Lymph Nodes ◽  
Initial Surgery ◽  
Retrospective Clinical Study

Abstract Objective: The objective of the study was to determine the outcome of surgical resection of metastatic papillary thyroid cancer (PTC) in cervical lymph nodes after failure of initial surgery and I131 therapy. Design: This was a retrospective clinical study. Setting: The study was conducted at a university-based tertiary cancer hospital. Patients: A cohort of 95 consecutive patients with recurrent/persistent PTC in the neck underwent initial reoperation during 1999–2005. All had previous thyroidectomy (±nodal dissection) and I131 therapy. Twenty-five patients with antithyroglobulin (Tg) antibodies were subsequently excluded. Main Outcome Measures: Biochemical complete remission (BCR) was stringently defined as undetectable TSH-stimulated serum Tg. Results: A total of 107 lymphadenectomies were undertaken in these 70 patients through January 2010. BCR was initially achieved in 12 patients (17%). Of the 58 patients with detectable postoperative Tg, 28 had a second reoperation and BCR was achieved in five (18%), seven had a third reoperation, and none achieved BCR. No patient achieving BCR had a subsequent recurrence after a mean follow-up of 60 months (range 4–116 months). In addition, two more patients achieved BCR during long-term follow-up without further intervention. In total, 19 patients (27%) achieved BCR and 32 patients (46%) achieved a TSH-stimulated Tg less than 2.0 ng/ml. Patients who did not achieve BCR had significant reduction in Tg after the first (P < 0.001) and second (P = 0.008) operations. No patient developed detectable distant metastases or died from PTC. Conclusions: Surgical resection of persistent PTC in cervical lymph nodes achieves BCR, when most stringently defined, in 27% of patients, sometimes requiring several surgeries. No biochemical or clinical recurrences occurred during follow-up. In patients who do not achieve BCR, Tg levels were significantly reduced. The long-term durability and impact of this intervention will require further investigation.

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