scholarly journals Brain Metastasis of Nasopharyngeal Carcinoma: A Case Report and Literature Review

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Orit Kaidar-Person ◽  
Jonathan Kuten ◽  
Fadi Atrash ◽  
Salem Billan ◽  
Abraham Kuten
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Nasopharyngeal Carcinoma ◽  
Brain Metastasis ◽  
Database Search ◽  
Solitary Brain Metastasis ◽  
Search Terms ◽  
Pubmed Database ◽  
Central Nervous System Metastases

Central nervous system metastases from nasopharyngeal carcinoma (NPC) are uncommon. The patient presented was diagnosed with aggressive advanced NPC resistant to treatment and complicated by a solitary brain metastasis. A PubMed database search was conducted to review the existing literature regarding brain metastases of NPC, using the search terms “nasopharyngeal neoplasia,” “nasopharyngeal carcinoma,” “nasopharynx,” “radiotherapy,” “central nervous system,” and “brain” in section of “Title/Abstract.” The articles were first evaluated by title and then by abstract, and thereafter appropriate manuscripts were evaluated by full text. References of the published papers were also reviewed.

scholarly journals Central Nervous System Miliary Brain Metastasis Secondary to Breast Cancer: Case Report

Cureus ◽  
2020 ◽  
Author(s):  
Gabriel Santos Vázquez ◽  
Ricardo Garcia Cázarez ◽  
Erick Moreno Pizarro ◽  
Aarón Emanuel Serrano Padilla ◽  
Juan Carlos Plascencia Salcedo
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Brain Metastasis ◽  
Breast Cancer Case ◽  
Cancer Case

scholarly journals Central Nervous System Metastases from Ewing''s Sarcoma —Case Report—

1994 ◽  
Vol 34 (11) ◽  
pp. 754-758 ◽  
Author(s):  
Hidekatsu MIZUSHIMA ◽  
Hiroyuki JINBO ◽  
Motohiko SHIMAZU ◽  
Takashi ABE ◽  
Norihiko KUNII ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Central Nervous System Metastases

scholarly journals Delayed Cerebral Metastasis of Breast Cancer: Case Report and Molecular Review

2019 ◽  
Vol 38 (04) ◽  
pp. 336-341
Author(s):  
Leonardo Dessesards Olijnyk ◽  
Artur Nobrega Lima Morais ◽  
Rodolfo Figueiredo Carvalho ◽  
Adriana Abrão ◽  
Krunal Patel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Brain Metastasis ◽  
Molecular Subtypes ◽  
Breast Cancer Case ◽  
Cerebral Metastasis ◽  
Cancer Case ◽  
Prevalent Disease

AbstractBreast cancer (BC) is a prevalent disease, and its incidence of brain metastasis (BM) varies from 5 to 30% according to the literature. We present the case of a delayed isolated cerebral metastasis in a female patient following a period of 16 years after the diagnosis and first treatment. During this time, there was no other recurrence. We also review the literature concerning central nervous system spread and the molecular subtypes of such late tumors.

Isolated Central Nervous System Metastasis from Ovarian Carcinoma: A Case Report

1989 ◽  
Vol 75 (2) ◽  
pp. 181-182 ◽  
Author(s):  
Gianmaria Bonardi ◽  
Michela Donadio ◽  
Franco Maestroni ◽  
Giuseppe Giaccone ◽  
Alessandro Calciati
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Ovarian Carcinoma ◽  
Abdominal Cavity ◽  
Pathological Response ◽  
Central Nervous System Metastasis ◽  
Ovarian Adenocarcinoma ◽  
Central Nervous System Metastases ◽  
Intracranial Recurrence

Ovarian adenocarcinoma usually disseminates and recurs the abdominal cavity. The detection of central nervous system metastases is rare. In this report we describe a case of intracranial recurrence that developed during a complete local surgical and pathological response and was treated radically with surgery followed by radiation.

scholarly journals Nasopharyngeal carcinoma with central nervous system metastases

Medicine ◽  
2017 ◽  
Vol 96 (49) ◽  
pp. e9175 ◽  
Author(s):  
Chunying Shen ◽  
Hongmei Ying ◽  
Xueguan Lu ◽  
Chaosu Hu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Nasopharyngeal Carcinoma ◽  
Central Nervous System Metastases

scholarly journals Targeted Therapy Using the Selective Tropomyosin Kinase Receptor Inhibitor Larotrectinib in an Infant with Infantile Fibrosarcoma with a TPM3–NTRK1 Gene Fusion with Lung and Central Nervous System Metastases: Case Report

2021 ◽  
pp. 1-6
Author(s):  
Fabricio T Romagnol ◽  
Eliana M Caran ◽  
Fabricio T Romagnol ◽  
Sérgio Cavalheiro ◽  
Marcelo de Toledo Petrilli ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Targeted Therapy ◽  
Gene Fusion ◽  
Molecular Testing ◽  
Durable Response ◽  
Infantile Fibrosarcoma ◽  
Antibody Staining ◽  
Central Nervous System Metastases

This case report describes the outcomes of tropomyosin receptor kinase (TRK) inhibitor treatment in an infant with an infantile fibrosarcoma (IFS) with a TPM3–NTRK1 gene fusion. The IFS on the left foot was refractory to chemotherapy and was partially resected. After 5 months, there was local recurrence and further surgery was performed. The patient developed pulmonary and central nervous system metastases. Pan-TRK antibody staining was positive and genomic profiling with next-generation sequencing confirmed a TPM3–NTRK1 gene fusion. The patient started treatment with larotrectinib in February 2019, with a durable response, including a clear reduction in brain metastases. Research on novel gene fusions and molecular testing to direct the use of targeted therapy should be encouraged, especially in refractory solid tumors.

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