scholarly journals Potential Antiosteoporotic Agents from Plants: A Comprehensive Review

2012 ◽  
Vol 2012 ◽  
pp. 1-28 ◽  
Author(s):  
Min Jia ◽  
Yan Nie ◽  
Da-Peng Cao ◽  
Yun-Yun Xue ◽  
Jie-Si Wang ◽  
...  

Osteoporosis is a major health hazard and is a disease of old age; it is a silent epidemic affecting more than 200 million people worldwide in recent years. Based on a large number of chemical and pharmacological research many plants and their compounds have been shown to possess antiosteoporosis activity. This paper reviews the medicinal plants displaying antiosteoporosis properties including their origin, active constituents, and pharmacological data. The plants reported here are the ones which are commonly used in traditional medical systems and have demonstrated clinical effectiveness against osteoporosis. Although many plants have the potential to prevent and treat osteoporosis, so far, only a fraction of these plants have been thoroughly investigated for their physiological and pharmacological properties including their mechanism of action. An attempt should be made to highlight plant species with possible antiosteoporosis properties and they should be investigated further to help with future drug development for treating this disease.

2020 ◽  
Vol 10 (5) ◽  
pp. 543-549
Author(s):  
Vijay Chopra ◽  
Aishwarya Shriwastva ◽  
Gopal L. Khatik ◽  
Manish Vyas ◽  
Pramod Yadav ◽  
...  

Background: Abrus precatorius L. (A. precatorius) is a valuable plant from the family Fabaceae which is a pea family. It is commonly known as Gunja or Jequirity, significantly found throughout India mainly Himalaya to Southern India and Ceylon. It is considered a poisonous plant due to the presence of abrin. Objective: A. precatorius has many pharmacological and biologically active constituents, such as alkaloids, glycosides and flavonoids situated in different parts of the plant. The objective of this review is to provide a retrospective study based on its anticancer potential. Results: Recent studies of A. precatorius are based on the isolation, characterization, and pharmacological evaluation of different secondary metabolites. These constituents possess significant cytotoxic properties against various cancer cell lines including breast, lung, liver, ovarian, prostate and leukaemia. A. precatorius is also reported to have anti-diabetic, anti-microbial, abortifacient, antioxidant, anthelmintic activity, antifertility, nephroprotective, and immunomodulatory activities. Conclusion: The present review summarizes the anticancer potential of A. precatorius and its constituents. However, extensive research is required to establish it as a potent chemotherapeutic agent.


Author(s):  
SULEIMAN OLIMAT

This is a specific review of Vitex agnus-castus L. (chasteberry) known as Finjinkest and Shajrat Ibrahim (Abraham’s tree) in Arabic, focusing in the current application: V. agnus-castus is listed among other medicinal plants in the ancient book “Al-Kulliyat Fi A-Tibb,” written by the famous Andulasin Philosopher Ibn Rushd. The focus of the study is to review only the uses mentioned in the book, review up to date literature (e.g., Google Scholar, PubMed, and Scopus) and analyzing the current pharmacological properties in link to the active constituents of the plant. The purpose of the present study is to confirm the uses of V. agnus-castus mentioned by Ibn Rushd with modern scientific and pharmacological research. Ethnopharmacological research confirming the uses mentioned by Ibn Rushd, such as treatment internal organs, liver and spleen, erectile dysfunction, and offspring. The results give further insights into the pharmacological activity of V. agnus-castus and confirm the different uses mentioned by Ibn Rushd.


2020 ◽  
Vol 7 (06) ◽  
pp. 4841-4844
Author(s):  
Suleiman Olimat

  Background: This is a specific review of Achillea millefoilum L. (Yarrow), known as Qaisum in Arabic, focusing in the current application. Purpose: The purpose of the present study is to confirm the uses of Achillea millefoilum  mentioned by Ibn Rushd with modern scientific and pharmacological research. Study Design:  Achillea millefoilum  is listed among other medicinal plants in the ancient book  “Al-Kulliyat Fi A-Tibb”, written by the famous Andulasi Philosopher Ibn Rushd. The focus of the study is to review only  the uses mentioned in the book, review up to date literature (e.g. Google Scholar, PubMed, Scopus) and analyzing the current pharmacological properties in link to the active constituents of the plant. Results: Ethnopharmacological research confirming the uses mention by Ibn Rusd, such as alopecia and its relation with castor oil and pumpkin, in addition to its application for the treatment of skin disorders.  Conclusion: The results give further insights into the pharmacological activity of A.  millefolium   and confirm the different uses mentioned by Ibn Rusd.


Author(s):  
Pavani C H

Hyperlipidemia is the immediate results of the excessive fat intake in food. This results in the elevated levels of cholesterol and triglycerides in the blood. This leads to heart conditions like CAD, hypertension, congestive heart failure as risk factors which can be lethal. There are many drugs to treat and control the lipids levels in the body. These drugs are either designed to prevent LDL accumulation and VLDL synthesis. Some drugs also lower the elevated levels of saturated lipids in the body. But many drugs are known to cause side effects and adverse effects; therefore, alternatives to the drugs are the subjects for current investigations. Herbs and medicinal plants are used as treatment sources for many years. They have been used in the Indian medical systems like Ayurveda, Siddha etc. As the application of herbs in the treatment is growing, there is an urgent need for the establishment of Pharmacological reasoning and standardization of the activity of the medicinal plants. Chloris paraguaiensis Steud. is Poyaceae member that is called locally as Uppugaddi. Traditionally it is used to treat Rheumatism, Diabetes, fever and diarrhoea. The chemical constituents are known to have anti-oxidant properties and most of the anti-oxidants have anti-hyperlipidemic activity too. Since the plant has abundant flavonoid and phenol content, the current research focusses on the investigation of the anti-hyperlipidemic activity of the plant Chloris extracts. Extracts of Chloris at 200mg/kg showed a comparably similar anti hyperlipidemia activity to that of the standard drug. The extracts showed a dose based increase in the activity at 100 and 200mg/kg body weight.


2019 ◽  
Vol 5 (3) ◽  
pp. 170-231
Author(s):  
Minky Mukhija ◽  
Bhuwan Chandra Joshi

Background: Peptic ulcer is a deep gastrointestinal erosion disorder that involves the entire mucosal thickness and can even penetrate the muscular mucosa. Nowadays, several plants and compounds derived from it have been screened for their antiulcer activity. In the last few years, there has been an exponential growth in the field of herbal medicine. This field has gained popularity in both developing and developed countries because of their natural origin and less side effects. Objective: This review aims to provide a comprehensive summary of currently available knowledge of medicinal plants and phytoconstituents reported for their anti-ulcer properties. Methods: The worldwide accepted database like SCOPUS, PUBMED, SCIELO, NISCAIR, ScienceDirect, Springerlink, Web of Science, Wiley, SciFinder and Google Scholar were used to retrieve available published literature. Results: A comprehensive review of the present paper is an attempt to list the plants with antiulcer activity. The review narrates the dire need to explore potential chemical moieties that exert an antiulcer effect, from unexploited traditional plants. Furthermore, the present study reveals the intense requirement to exploit the exact mechanism through which either the plant extracts or their active constituents exhibit their antiulcer properties. Conclusion: This article is the compilation of the plants and its constituents reported for the treatment of peptic ulcers. The Comprehensive data will surely attract the number of investigators to initiate further research that might lead to the drugs for the treatment of ulcers. As sufficient scientific data is not available on plants, most of the herbals cannot be recommended for the treatment of diseases. This can be achieved by research on pure chemical structures derived from plants or to prepare new lead compounds with proven beneficial preclinical in vitro and in vivo effects. However, a lot remains to be done in further investigations for the better status of medicinal plants.


2021 ◽  
Vol 85 ◽  
pp. 104638
Author(s):  
Chun-xiao Li ◽  
Tian-hao Li ◽  
Mei Zhu ◽  
Jiang Lai ◽  
Zhi-peng Wu

1988 ◽  
Vol 108 (5) ◽  
pp. 450-453
Author(s):  
TOSIHIKO SUMIDA ◽  
HIROYUKI SUGIMOTO ◽  
TOHRU FUWA ◽  
KAZUO YAMASAKI ◽  
OSAMU TAKEDA ◽  
...  

Author(s):  
Fatemeh Hosseinpour-Jaghdani ◽  
Tahoora Shomali ◽  
Sajedeh Gholipour-Shahraki ◽  
Mohammad Rahimi-Madiseh ◽  
Mahmoud Rafieian-Kopaei

AbstractMedicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties.


Author(s):  
S. Mounika ◽  
R. Jayaraman ◽  
D. Jayashree ◽  
K. Hanna Pravalika ◽  
Anna Balaji ◽  
...  

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