scholarly journals Bacillus cereusBloodstream Infection in a Preterm Neonate Complicated by Late Meningitis

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Toshinobu Horii ◽  
Kiyoko Tamai ◽  
Shigeyuki Notake ◽  
Hideji Yanagisawa
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Bacillus Cereus ◽  
Gel Electrophoresis ◽  
Preterm Neonate ◽  
Pulsed Field Gel Electrophoresis ◽  
Central Nervous System Infections ◽  
Acute Meningitis

Central nervous system infections caused byBacillus cereushave rarely been reported in infants. In this paper, the case of a 2-month-old low-birth-weight female who developed meningitis 45 days after resolution of a bloodstream infection (BSI) is described. The pulsed-field gel electrophoresis results revealed that the patterns of bothB. cereusisolates responsible for the acute meningitis and for the prior bacteraemic episode were closely related. Although the source of the infection from within the patient was not clear, it is suggested that theB. cereusBSI developed in the neonate was complicated by acute meningitis.

LABORATORY CRITERIA OF PERINATAL DAMAGE OF CENTRAL NERVOUS SYSTEM AT PREMATURE NEWBORNS

2019 ◽  
Vol 72 (8) ◽  
pp. 1512-1516
Author(s):  
Viktoria A. Petrashenko ◽  
Andrii M. Loboda ◽  
Olexandr I. Smiyan ◽  
Sergii V. Popov ◽  
Svetlana N. Kasyan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Neonatal Period ◽  
Metabolic Effect ◽  
Premature Newborns ◽  
Premature Children ◽  
Cns Lesions

Introduction: Fetal and neonatal hypoxia takes a special place among the damaging factors of central nervous system (CNS). All forms of oxygen deficiency are accompanied by the development of bioenergetic hypoxia, which leads to tension of metabolic processes of the organism. Metabolic effect of hypoxia includes stark reduce of mitochondrial activity due to a significant inhibition enzymes of the Krebs cycle: succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH). In newborn babies is not always possible to objectively assess the condition of the CNS defeat, because very often the severity of lesions does not correspond to clinical symptoms, especially in premature newborns. So far determination the severity of hypoxic-ischemic CNS lesions is still very actual in modern medicine. More objective method of such an assessment is determine the activity of neurospecific enolase (NSE). The aim of the paper is to increase the efficiency of diagnosis of hypoxic CNS lesions in premature infants by determining the activity of NSE and study energy supply during the neonatal period. Materials and methods: The concentration of NSE, SDH and LDH were determined in 15 conventionally healthy preterm infants (CHPI), which made the comparison group, and 64 premature babies with hypoxic-ischemic CNS lesions, which were divided into three groups: I group – 26 premature children with mild CNS lesions; II group – 20 premature children with severe hypoxic lesions and low birth weight; III group – 18 premature newborns with severe damage of central nervous system and extremely low birth weight. NSE activity was determined by enzyme immunoassay using reagents of the company «Fujirebio» (Sweden) on an automatic analyzer «Multiscan Plus» company «Labsystems» (Finland). Material for investigation was peripheral venous blood of newborns, which collected by vein punction at morning on an empty stomach. Results and conclusions: Metabolic effect of hypoxia in premature infants manifested by severe inhibition of mitochondrial respiratory activity, which appears in the reduction of aerobic enzyme activity of SDH and activation serum LDH. During the neonatal period in infants with perinatal hypoxic- ischemic lesions of the CNS levels of the of NSE, SDH and LDG aren’t normalized, that indicated on energy deficiency and requires the development of effective methods of correcting this condition. Perinatal hypoxia in premature neonates causes significant alteration of neuronal membranes and increase concentration in blood such neurospecific protein as NSE, whose concentration correlates with the degree of severity of CNS injury.

scholarly journals Cryptococcus laurentii fungemia in a low birth weight preterm neonate: India

2018 ◽  
Vol 11 (6) ◽  
pp. 896-897 ◽  
Author(s):  
Minakshi Gupta ◽  
Asit K. Mishra ◽  
Santosh K. Singh
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Neonate ◽  
Cryptococcus Laurentii

Management of central nervous system infections during an epidemic of enteroviral aseptic meningitis

1980 ◽  
Vol 96 (3) ◽  
pp. 559-563 ◽  
Author(s):  
Jonathan I. Singer ◽  
Philip R. Maur ◽  
John P. Riley ◽  
Pamela Burger Smith
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Aseptic Meningitis ◽  
Central Nervous System Infections

Diffusion imaging in pediatric central nervous system infections

2001 ◽  
Vol 43 (12) ◽  
pp. 1031-1039 ◽  
Author(s):  
J. Teixeira ◽  
R. Zimmerman ◽  
J. Haselgrove ◽  
L. Bilaniuk ◽  
J. Hunter
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Diffusion Imaging ◽  
Central Nervous System Infections
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