scholarly journals Small Cell Carcinoma of the Larynx Treated by Concurrent Chemoradiotherapy: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Susumu Nakahara ◽  
Norihiko Takemoto ◽  
Hidenori Inohara
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Organ Preservation ◽  
Concurrent Chemoradiotherapy ◽  
Complete Response ◽  
Small Cell ◽  
Intensive Chemotherapy ◽  
Rare Entity ◽  
Carcinoma Of The Larynx ◽  
First Interview

Small cell carcinoma (SmCC) generally occurs in the lung and extrapulmonary SmCC is a relatively rare entity. Here, we present a case of a 42-year-old male with SmCC of the larynx diagnosed as cT3N0M0. Concurrent chemoradiotherapy using cisplatin (CDDP) and etoposide (VP-16) was given, which achieved complete response (CR). Lung metastasis became evident in 16 months whereas the locoregional control remained good. In spite of intensive chemotherapy using CDDP and irinotecan (CPT-11), the patient died of disease in 34 months after the first interview. Since the prognosis of laryngeal SmCC is extremely poor, organ preservation therapy should be considered instead of radical laryngectomy.

scholarly journals Distal Humerus as Delayed Site of Metastasis from Small Cell Carcinoma of Gallbladder

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Mutahir A. Tunio ◽  
Mushabbab AlAsiri ◽  
Asma Mohammed F. Ali ◽  
Eyad Fawzi AlSaeed ◽  
Muhammad Shuja ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
World Literature ◽  
Case Reports ◽  
Locally Advanced ◽  
Distal Humerus ◽  
Small Cell ◽  
Rare Entity ◽  
Dismal Prognosis ◽  
Advanced Stages

Background. Small cell carcinoma (SCC) of the gallbladder is a rare entity and is often seen in elderly women. SCC of gallbladder is typically a nonsecretory carcinoid tumor without overt clinical symptoms and is often discovered at advanced stages. SCC of gallbladder carries a dismal prognosis as compared to SCC of lung and adenocarcinoma of gallbladder. To date, only 73 case reports have been published in the world literature.Case Presentation. Herein, we report a case of a 73-year-old Saudi woman who presented with one week history of right upper quadrant abdominal pain and obstructive jaundice and was found to be a case of locally advanced, metastatic SCC of gallbladder cT4N1M1 (liver, para-aortic lymph nodes, and bone). The patient was treated with neoadjuvant etoposide and cisplatin (EP) chemotherapy three cycles after biliary stenting followed by radical cholecystectomy, lymphadenectomy, and adjuvant EP chemotherapy and then one year later developed distal humerus osseous metastasis.Conclusion. SCC of the gallbladder is very rare entity and is often seen at advanced stages. Osseous metastases of peripheral skeleton from SCC gallbladder are rarely reported. Surgery is curative option but only for early stage tumors. Incorporation of chemotherapy along with radical resection increases the survival.

Primary Combined Squamous and Small Cell Carcinoma of the Larynx: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (11) ◽  
pp. 1279-1282
Author(s):  
Vilkesh R. Jaiswal ◽  
Mai P. Hoang
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Squamous Cell ◽  
Small Cell ◽  
Squamous Cell Carcinomas ◽  
Review Of The Literature ◽  
The Past ◽  
Laryngeal Carcinomas ◽  
Carcinoma Of The Larynx ◽  
Combined Small Cell Carcinoma

Abstract Primary laryngeal carcinomas comprise approximately 2% to 5% of all malignancies worldwide. Of these laryngeal carcinomas, approximately 99% are primary squamous cell carcinomas. During the past 30 years, about 160 cases of primary small cell carcinoma of the larynx have been reported. Combined primary squamous and small cell carcinoma of the larynx, the so-called composite tumor of the larynx, is even more rare, with only 13 published cases to date. Although the major risk factors for developing these composite tumors of the larynx are thought to be similar to other more common neoplasms of the larynx, such as squamous cell carcinoma, the treatment and prognosis are different. We report an additional case of combined small cell carcinoma of the larynx and discuss the histogenesis of this unusual neoplasm.

Synchronous sporadic medullary carcinoma of the thyroid and small-cell carcinoma of lung: A rare entity

2013 ◽  
Vol 2 (2) ◽  
pp. 170
Author(s):  
Manigreeva Krishnatreya ◽  
Tashnin Rahman ◽  
Jagannath Sharma ◽  
Amal Kataki
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Medullary Carcinoma ◽  
Small Cell ◽  
Rare Entity

scholarly journals Complete Response of Recurrent Small Cell Carcinoma of the Uterine Cervix to Paclitaxel, Carboplatin, and Bevacizumab Combination Therapy

2020 ◽  
Vol 13 (1) ◽  
pp. 373-378 ◽  
Author(s):  
Yuri Nakao ◽  
Satoshi Tamauchi ◽  
Nobuhisa Yoshikawa ◽  
Shiro Suzuki ◽  
Hiroaki Kajiyama ◽  
...  
Keyword(s):  
Lymph Node ◽  
Combination Therapy ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Uterine Cervix ◽  
Posterior Wall ◽  
Complete Response ◽  
Uterine Sarcoma ◽  
Small Cell ◽  
Lymph Node Sampling

We report a case of recurrent small cell carcinoma of the uterine cervix that showed a complete response to paclitaxel, carboplatin, and bevacizumab (TC + Bev) combination therapy. Small cell carcinoma of the uterine cervix is extremely rare, with an incidence of only 1.3% in Japan, and a poor outcome. The patient was a 62-year-old woman with a chief complaint of irregular vaginal bleeding. Magnetic resonance imaging showed a 10-cm irregular mass from the uterine corpus’s posterior wall to the cervix. Abdominal total hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node sampling were performed for suspected uterine sarcoma. Histopathological findings revealed small cell carcinoma with lymph node metastasis. Although 6 cycles of etoposide + cisplatin were performed, para-aortic lymph node recurrence was found 3 months after chemotherapy. Subsequently, the patient received 8 cycles of TC + Bev, which eliminated the metastases. The patient is currently alive at 24 months.

scholarly journals Primary small cell carcinoma of the larynx. Survival time of 47 months. Case report

2018 ◽  
Vol 30 ◽  
pp. 46-49 ◽  
Author(s):  
A. Raposo ◽  
A. Marco ◽  
M.E. García-Solano ◽  
M.J. Martínez-Ortiz ◽  
F. García-Purriños ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Survival Time ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Larynx

Small Cell Carcinoma of the Larynx: A Case Report

2005 ◽  
Vol 133 (4) ◽  
pp. 647-647 ◽  
Author(s):  
Ossama Hamid ◽  
Lobna El Fiky ◽  
Lobna Ezz El Arab ◽  
Yasser El Beltagy ◽  
Ragaa Amin
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Carcinoma Of The Larynx

Neuro-endocrine tumours of the head and neck

1990 ◽  
Vol 104 (6) ◽  
pp. 504-507 ◽  
Author(s):  
A. C. Soussi ◽  
A. Benghiat ◽  
C. S. Holgate ◽  
B. Majumdar
Keyword(s):  
Cell Carcinoma ◽  
Head And Neck ◽  
Small Cell Carcinoma ◽  
Neuroendocrine Carcinoma ◽  
Large Cell Carcinoma ◽  
Large Cell ◽  
Differential Response ◽  
Small Cell ◽  
Endocrine Tumours ◽  
Carcinoma Of The Larynx

AbstractWe report two types of neuroendocrine carcinoma of the head and neck, small cell carcinoma of the ethmoid and large cell carcinoma of the larynx, demonstrating a differential response to radiotherapy.

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