scholarly journals Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Qi Jin ◽  
Erzhen Chen ◽  
Jie Jiang ◽  
Yiming Lu
Keyword(s):  
Liver Transplantation ◽  
Hepatic Failure ◽  
Heat Stroke ◽  
Acute Hepatic Failure ◽  
Exertional Heat Stroke ◽  
Case Presentation ◽  
Significant Prolongation ◽  
Leading Symptom ◽  
Supportive Management ◽  
Hepatocyte Growth

Background. Acute hepatic failure (AHF) is uncommon as a leading symptom in patients with exertional heat stroke (EHS). Which stage to perform the liver transplantation for severe hepatic failure in EHS is still obscure at clinical setting. The conservative management has been reported to be successful in treating heat-stroke-associated AHF even in the presence of accepted criteria for emergency liver transplantation.Case Presentation. Here, we reported a 35-year-old male who presented with very high transaminases, hyperbilirubinemia, significant prolongation of the prothrombin time, and coma. No other causes for AHF could be identified but physical exhaustion and hyperthermia. Although the current patient fulfilled London criteria for emergency liver transplantation, he spontaneously recovered under conservative treatment including intravenous fluids, cooling, diuretics as mannitol, and hepatocyte growth-promoting factors.Conclusions. Meticulous supportive management could be justified in some selected cases of AHF due to EHS.

A Case of Exertional Heat Stroke with Acute Hepatic Failure Treated with Plasma Exchange - A Case Report -

2012 ◽  
Vol 27 (2) ◽  
pp. 130 ◽  
Author(s):  
Young Joo Han ◽  
Jae Wook Choi ◽  
Woo Jin Chung ◽  
Dong In Suh ◽  
June Dong Park
Keyword(s):  
Case Report ◽  
Plasma Exchange ◽  
Hepatic Failure ◽  
Heat Stroke ◽  
Acute Hepatic Failure ◽  
Exertional Heat Stroke

scholarly journals Fatal neurological complication after liver transplantation in acute hepatic failure patient with hepatic encephalopathy

2018 ◽  
Vol 33 (1) ◽  
pp. 96
Author(s):  
Joo-Yun Kim ◽  
Hyun-Su Ri ◽  
Ji-Uk Yoon ◽  
Eun-Ji Choi ◽  
Hye-Jin Kim ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatic Encephalopathy ◽  
Hepatic Failure ◽  
Neurological Complication ◽  
Acute Hepatic Failure

scholarly journals The Fire from Within: Multiorgan Failure with Bimodal Rhabdomyolysis from Exertional Heat Stroke

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Onion Gerald V. Ubaldo ◽  
Khia Quiwa ◽  
Rohana Elise Rollan ◽  
Edhel Tripon ◽  
Elizabeth Sebastian
Keyword(s):  
Liver Transplantation ◽  
Liver Failure ◽  
Liver Transplant ◽  
Core Body Temperature ◽  
Multiorgan Failure ◽  
Heat Stroke ◽  
Exertional Heat Stroke ◽  
Liver Support ◽  
Central Nervous System Dysfunction ◽  
Extracorporeal Liver Support

Heat stroke (HS) is a condition characterized by a rise in core body temperature and central nervous system dysfunction. It is divided into two types: classical and exertional. Exertional heat stroke (EHS) is accompanied by organ failure. Liver injury, presenting only with a rise in liver enzymes, is common but in rare conditions, acute liver failure (ALF) may ensue, leading to a potentially lethal condition. Most cases of EHS-induced ALF are managed conservatively. However, liver transplantation is considered for cases refractory to supportive treatment. Identifying patients eligible for liver transplantation in the context of an EHS-induced ALF becomes a medical dilemma since the conventional prognostic criterion may be difficult to apply, and there is paucity of literature about these specific sets of individuals. Recently, extracorporeal liver support has been gaining popularity for patients with liver failure as a bridge to liver transplant. In this case report, we present a young Filipino athlete with symptoms and clinical course consistent with EHS that developed multiorgan failure, initially considered a candidate for liver transplant and total plasma exchange, but clinically improved with supportive management alone. This patient was also found to have bimodal rhabdomyolysis during the course of his hospital stay as manifested by the bimodal rise in his creatine kinase enzymes.

Diagnosis and assessment of acute hepatic failure in the critically ill

2016 ◽  
Author(s):  
Sameer Patel ◽  
Julia Wendon
Keyword(s):  
Liver Transplantation ◽  
Risk Stratification ◽  
Critically Ill ◽  
Clinical Assessment ◽  
Hepatic Failure ◽  
Rapid Assessment ◽  
Acute Hepatic Failure ◽  
Differential Diagnoses ◽  
Life Saving ◽  
Specialist Centre

Establishing the aetiology of acute hepatic failure is essential for correct and timely management. An exhaustive history and examination is crucial in targeting investigations and initiating management. Clinical assessment allows risk stratification, identifying those patients who can be managed locally from those best served in a specialist centre with liver transplantation capability. History should focus on the presenting problem, time of onset and speed of deterioration, and establish features consistent with hyperacute, acute or subacute ALF to guide prognostication. Examination should initially focus on rapid assessment and resuscitation before searching for signs leading to more specific differential diagnoses. Investigations should encompass the variety of potential causes, ranging from basic to more specialist studies. Prognostication is critical for stratification of those patients who may benefit from a potentially life-saving transplantation. Several risk stratification and predictive tools exist to differentiate those patients likely to recover, those unlikely to survive despite maximal intervention, and those who would potentially benefit from transplantation.

Liver and intestinal lactate metabolism in patients with acute hepatic failure undergoing liver transplantation

2001 ◽  
Vol 29 (11) ◽  
pp. 2111-2118 ◽  
Author(s):  
Nick D. Murphy ◽  
Sadik K. Kodakat ◽  
Julia A. Wendon ◽  
Charl A. Jooste ◽  
Paolo Muiesan ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatic Failure ◽  
Acute Hepatic Failure ◽  
Lactate Metabolism

Liver transplantation in exertional heat stroke: a medical dilemma

2004 ◽  
Vol 30 (7) ◽  
Author(s):  
Eran Hadad ◽  
Ziv Ben-Ari ◽  
Yuval Heled ◽  
DanielS. Moran ◽  
Yoav Shani ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Heat Stroke ◽  
Exertional Heat Stroke
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