scholarly journals Impact of Laparoscopic Fundoplication for the Treatment of Laryngopharyngeal Reflux: Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Guilherme da Silva Mazzini ◽  
Richard Ricachenevsky Gurski
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastric Content ◽  
Antireflux Surgery ◽  
Laparoscopic Fundoplication ◽  
Laryngopharyngeal Reflux ◽  
Review Of The Literature ◽  
Proximal Esophagus ◽  
The Impact ◽  
Symptoms And Signs

Laryngopharyngeal reflux (LPR) is part of the so-called extraesophageal manifestations of gastroesophageal reflux disease (GERD). It is presented by unspecific symptoms and signs and is believed to be caused by the reflux of gastric content to the proximal esophagus and larynx. However, evidence considering the role of the antireflux surgery for LPR has failed to demonstrate results comparable to those for GERD. The aim of this paper is to review the current literature regarding the impact of laparoscopic fundoplication for the treatment of LPR.

Stages of the formation of temporary and permanent occlusion and the impact of early tooth extraction on the dentition state. Literature review

2019 ◽  
pp. 22-24
Author(s):  
G.A. Murachueva ◽  
I.M. Rasulov ◽  
S.G. Gusenov
Keyword(s):  
Literature Review ◽  
Temporomandibular Joint ◽  
Tooth Extraction ◽  
Physiological State ◽  
Review Of The Literature ◽  
Full Development ◽  
Permanent Occlusion ◽  
The Impact

A review of the literature on the stages of the formation of temporary and permanent occlusion has been performed. This stages play an important role not only for the full development of the maxillofacial apparatus, temporomandibular joint, but also the whole organism. The role of early tooth extraction in the formation of the physiological state of the dentoalveolar system is considered. The conclusion is drawn about the need for a deeper study of this problem in the structure of general dental morbidity.

Dangerous liaisons?

2008 ◽  
Vol 29 (1/2) ◽  
pp. 116-124 ◽  
Author(s):  
John Rodwell ◽  
Linden Fairbairn
Keyword(s):  
Design Methodology ◽  
Service Delivery Model ◽  
University Libraries ◽  
Review Of The Literature ◽  
Content Type ◽  
Role Description ◽  
Definition Of ◽  
The Impact ◽  
Practical Implications

PurposeMany university libraries are adopting a faculty liaison librarian structure as an integral part of their organization and service delivery model. This paper aims to examine, in a pragmatic way, the variations in the definition of the role of the faculty liaison librarian, the expectations of those librarians, their library managers and their clients and the impact of environmental factors. The faculty liaison librarian role is not entirely new, evolving from the traditional subject librarian and university special/branch library role. However the emerging role is characterized by a more outward‐looking perspective and complexity, emphasizing stronger involvement and partnership with the faculty and direct engagement in the University's teaching and research programs.Design/methodology/approachFollowing a review of the literature and other sources on the rationale and role of library liaison, the current developments, drivers and expectations are discussed.FindingsThe study finds that dynamic external and internal environments of universities are driving the evolution of library liaison, so the role description is still fluid. However, the breadth and weight of expectations is now such that the effectiveness and sustainability of the role has to be addressed.Practical implicationsWhile a dynamic, broader and more intensive role for the faculty liaison librarian is emerging, more thinking is needed about the extent of that role and its sustainability. What, for example, are the priorities for the faculty liaison librarian? What traditional activities can, and may, have to be abandoned? These considerations are necessary not only to guide the librarians, but also to help define the attributes and skills required for the position and to determine the institutional support it requires.Originality/valueThis is a contemporary critique of the well‐established, but diverse library service – the faculty liaison librarian structure.

scholarly journals Laryngopharyngeal reflux: clinical significance, modern approaches to diagnosis and treatment

2019 ◽  
pp. 8-16
Author(s):  
I. V. Maev ◽  
J. V. Selskaya ◽  
D. N. Andreev ◽  
D. T. Dicheva ◽  
Z. N. Bogolepova ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Gold Standard ◽  
Gastric Content ◽  
Laryngopharyngeal Reflux ◽  
Standard Dosage ◽  
No Gold Standard ◽  
Instrumental Methods ◽  
Ph Metry

Gastroesophageal reflux disease (GERD) is one of the most common pathologies in modern clinical practice. Laryngopharyngeal reflux (LPR) is considered to be an extraesophageal manifestation of GERD and is characterized by retrograde ingestion of gastric content into the larynx and pharynx, leading to recurrent otolaryngological symptoms. Classical manifestations of LPR are hoarseness, perspiration, dryness and feeling of lump in the throat, coughing. There is no «gold standard» for the diagnosis of LPR. At the same time, several instrumental methods are used in clinical practice to verify the diagnosis: laryngoscopy and EGDS are the most common, and in some cases - 24-hour pH-metry and impedancemetry. In the case of an established diagnosis of LPR, it is recommended to use a standard dosage of PPI twice a day for 3–6 months.

scholarly journals Hyperuricemia and chronic kidney disease

2021 ◽  
pp. 77-81
Author(s):  
Olga Kompaniets
Keyword(s):  
Chronic Kidney Disease ◽  
Uric Acid ◽  
Kidney Disease ◽  
Clinical Studies ◽  
Review Of The Literature ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

The article is devoted to a review of the literature on the impact of hyperuricemia on the development and progression of chronic kidney disease (CKD). The tendency of changes of views on the role of uric acid in the pathogenesis of CKD is demonstrated. An analysis of experimental, epidemiological and clinical studies on the effects of uric acid on the physiology of the nephron and endothelial tissues, the relationship of hyperuricemia with metabolic and cardiorenal syndromes.

End-of-life care volunteers: a systematic review of the literature

2005 ◽  
Vol 18 (4) ◽  
pp. 244-257 ◽  
Author(s):  
Donna M Wilson ◽  
Christopher Justice ◽  
Roger Thomas ◽  
Sam Sheps ◽  
Margaret MacAdam ◽  
...  
Keyword(s):  
End Of Life ◽  
End Of Life Care ◽  
Review Of The Literature ◽  
Volunteer Training ◽  
Care Services ◽  
Eol Care ◽  
The Impact ◽  
Organizational Needs ◽  
Meaningful Role

This report presents a review of 1988 and onwards research and other literature on end-of-life (EOL) care volunteers. Only 18 research or case studies articles were identified for an integrative review through a search of nine library databases. A review of this literature revealed three themes: (1) the roles of EOL volunteers, (2) volunteer training and other organizational needs or requirements, and (3) outcomes, particularly the impact of volunteering on volunteers and the impact of volunteers on EOL care. Despite limited statistical evidence, the available literature on EOL care volunteers clearly indicates that considerable potential benefit can be derived from EOL care volunteers' contributions, with their efforts benefiting dying persons, their families, paid EOL staff, and the volunteers themselves. More specifically, willing volunteers, particularly those with diverse skills and abilities, have the potential to significantly and positively impact EOL care in that they can perform many necessary and extra functions of value. Volunteers often augment and enhance the range of EOL care services provided to terminally ill individuals and their families. Volunteers should also be recognized as increasing the accessibility of EOL care. The role of the volunteer is not without challenge, however, both for the individuals who volunteer and the organizations that must orient them and provide a meaningful role for them.

scholarly journals Role of Trade in Growth and Poverty Reduction: A Review of Literature with Special Reference to India

2018 ◽  
Vol 4 (02) ◽  
Author(s):  
Komal . ◽  
Harinder Mohan
Keyword(s):  
International Trade ◽  
Poverty Reduction ◽  
International Market ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Firm Level ◽  
Poor Growth ◽  
Employment Effects ◽  
The Impact

The growing volumes of international trade and lowering of tariff barriers have triggered continuing debate and analysis on the impact of international trade on poverty. The United Nations has identified eradication of poverty – especially of extreme poverty – as its number one Millennium Development Goal (MDG). This paper tries to assess the relevance of trade in reducing poverty in India and promoting pro-poor growth through a survey of the existing literature and concludes that a strong performance on the international market can help reduce domestic poverty in developing countries. Through a review of the literature on this topic, the author finds that there is strong empirical evidence in favour of the growth enhancing effects of exports and trade in general. Furthermore, a number of detailed microeconomic studies using firm-level and household data show that exporting can lead to productivity, growth and directly reduce poverty through wage and employment effects.

scholarly journals The role of the p53 tumor suppressor in metabolism and diabetes

2016 ◽  
Vol 231 (2) ◽  
pp. R61-R75 ◽  
Author(s):  
Che-Pei Kung ◽  
Maureen E Murphy
Keyword(s):  
Tumor Suppression ◽  
Metabolic Diseases ◽  
Nucleotide Polymorphisms ◽  
Review Of The Literature ◽  
Single Nucleotide ◽  
Cycle Arrest ◽  
Transcription Factor P53 ◽  
The Impact ◽  
The Relationship

In the context of tumor suppression, p53 is an undisputedly critical protein. Functioning primarily as a transcription factor, p53 helps fend off the initiation and progression of tumors by inducing cell cycle arrest, senescence or programmed cell death (apoptosis) in cells at the earliest stages of precancerous development. Compelling evidence, however, suggests that p53 is involved in other aspects of human physiology, including metabolism. Indeed, recent studies suggest that p53 plays a significant role in the development of metabolic diseases, including diabetes, and further that p53’s role in metabolism may also be consequential to tumor suppression. Here, we present a review of the literature on the role of p53 in metabolism, diabetes, pancreatic function, glucose homeostasis and insulin resistance. Additionally, we discuss the emerging role of genetic variation in the p53 pathway (single-nucleotide polymorphisms) on the impact of p53 in metabolic disease and diabetes. A better understanding of the relationship between p53, metabolism and diabetes may one day better inform the existing and prospective therapeutic strategies to combat this rapidly growing epidemic.

scholarly journals Excess Body Weight and Gastroesophageal Reflux Disease

2021 ◽  
pp. 1-6
Author(s):  
Andreas Thalheimer ◽  
Marco Bueter
Keyword(s):  
Body Weight ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Gastric Content ◽  
Antireflux Surgery ◽  
Esophagogastric Junction ◽  
Mucosal Damage ◽  
Excess Body Weight ◽  
Retrograde Flow

<b><i>Background:</i></b> Gastroesophageal reflux disease (GERD) is strongly associated with excess body weight. <b><i>Summary:</i></b> GERD is characterized by typical symptoms with or without mucosal damage because of retrograde flow of gastric content into the esophagus. An ineffective esophagogastric junction (EGJ) combined with anatomical abnormalities is considered to be causative. The incidence of GERD is strongly associated with excess body weight, reflecting the pathophysiological relevance of the abdominothoracic pressure gradient. <b><i>Key Message:</i></b> Weight loss has been demonstrated to be an effective therapy for GERD combined with obesity. In cases in which surgical therapy is indicated, traditional antireflux surgery has led to equivocal results, advocating a proximal Roux-en-Y gastric bypass in these patients to correct both GERD and excess body weight.

scholarly journals The Role of Elective Neck Treatment in the Management of Sinonasal Carcinomas: A Systematic Review of the Literature and a Meta-Analysis

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1842
Author(s):  
Costanza Galloni ◽  
Luca Giovanni Locatello ◽  
Chiara Bruno ◽  
Angelo Cannavicci ◽  
Giandomenico Maggiore ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lower Risk ◽  
Meta Analysis ◽  
Regional Recurrence ◽  
Observation Group ◽  
Review Of The Literature ◽  
Impact On Survival ◽  
The Impact ◽  
Nodal Relapse

The impact of elective neck treatment (ENT), whether by irradiation or dissection, on the prognosis of patients with cN0 sinonasal carcinomas (SNCs) remains an understudied issue. METHODS: A systematic review and meta-analysis of the literature were performed according to PRISMA guidelines in order to assess regional nodal relapse rate after ENT compared to observation in cN0 SNCs patients. Twenty-six articles for a total of 1178 clinically N0 patients were analyzed. Globally, the 5-year overall survival was 52%; 34.6% of patients underwent ENT and 140 regional recurrences were registered (5.9% in the ENT cohort and 15% in the observation group). ENT appears to confer a lower risk of regional recurrence compared to observation alone, with a cumulative OR of 0.38 (95% CI 0.25–0.58). Our meta-analysis supports the efficacy of ENT for reducing the risk of regional recurrence, but its overall impact on survival remains uncertain.

scholarly journals Business knowledge absorptive capacity in micro and small innovative enterprises

2021 ◽  
pp. 3-14
Author(s):  
Edward Stawasz ◽  
Keyword(s):  
Absorptive Capacity ◽  
Business Management ◽  
Management Development ◽  
Review Of The Literature ◽  
Services Research ◽  
Operational Management ◽  
Business Knowledge ◽  
Level Of Knowledge ◽  
The Impact

Purpose – The aim of the presented article is to assess the impact of the capacity to absorb business advice on the improvement of business knowledge, and indirectly, on raising the level of strategic and operational management in micro and small innovative enterprises using business advice services. Research method – A review of the literature on examining the specificity of knowledge and management development in enterprises, the role of business advice and the capacity to absorb knowledge in this process. The second part of the article presents the results of the empirical research carried out using the CATI technique on a sample of 400 micro and small innovative Polish enterprises using business advice services. Results – The use of business advice services and the level of knowledge absorptive capacity increase the level of business knowledge of managers. The capacity to absorb knowledge positively moderates the impact of business advice on the level of business knowledge of managers, and, consequently, on the level of strategic and operational management. Originality /value – The research confirms the influence of the capacity to absorb knowledge on the level of knowledge of managers. Improving the level of knowledge and business management requires the use of business advice as well as the capacity to absorb knowledge.

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