scholarly journals American Visceral Leishmaniasis: Factors Associated with Lethality in the State of São Paulo, Brazil

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Geraldine Madalosso ◽  
Carlos Magno Fortaleza ◽  
Ana Freitas Ribeiro ◽  
Lisete Lage Cruz ◽  
Péricles Alves Nogueira ◽  
...  

Objectives. To identify factors associated with death in visceral leishmaniasis (VL) cases.Patients and Methodology. We evaluated prognostic factors for death from VL in São Paulo state, Brazil, from 1999 to 2005. A prognostic study nested in a clinical cohort was carried out by data analysis of 376 medical files. A comparison between VL fatal cases and survivors was performed for clinical, laboratory, and biological features. Association between variables and death was assessed by univariate analysis, and the multiple logistic regression model was used to determine adjusted odds ratio for death, controlling confounding factors.Results. Data analysis identified 53 fatal cases out of 376 patients, between 1999 and 2005 in São Paulo state. Lethality was 14.1% (53/376), being higher in patients older than fifty years. The main causes of death were sepsis, bleeding, liver failure, and cardiotoxicity due to treatment. Variables significantly associated with death were severe anemia, bleeding, heart failure, jaundice, diarrhea, fever for more than sixty days, age older than fifty years, and antibiotic use.Conclusion. Educational health measures are needed for the general population and continuing education programs for health professionals working in the affected areas with the purpose of identifying and treating early cases, thus preventing the disease evolution towards death.

Author(s):  
Fernando P. F. Zorzenon ◽  
Arthur F. Tomaseto ◽  
Matthew P. Daugherty ◽  
João R. S. Lopes ◽  
Marcelo P. Miranda

Acta Tropica ◽  
2016 ◽  
Vol 164 ◽  
pp. 233-242 ◽  
Author(s):  
Agda Maria Oliveira ◽  
Carolina Portugal Vieira ◽  
Margareth Regina Dibo ◽  
Marluci Monteiro Guirado ◽  
Lilian Aparecida Colebrusco Rodas ◽  
...  

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Lourdes Aparecida Zampieri D’Andrea ◽  
Elivelton da Silva Fonseca ◽  
Luiz Euribel Prestes-Carneiro ◽  
Raul Borges Guimarães ◽  
Renata Corrêa Yamashita ◽  
...  

2012 ◽  
Vol 28 (10) ◽  
pp. 1949-1964 ◽  
Author(s):  
Vanessa Aparecida Feijó de Souza ◽  
Luiz Ricardo Paes de Barros Cortez ◽  
Ricardo Augusto Dias ◽  
Marcos Amaku ◽  
José Soares Ferreira Neto ◽  
...  

A space-time analysis of American visceral leishmaniasis (AVL) in humans in the city of Bauru, São Paulo State, Brazil was carried out based on 239 cases diagnosed between June 2003 and October 2008. Spatial analysis of the disease showed that cases occurred especially in the city's urban areas. AVL annual incidence rates were calculated, demonstrating that the highest rate occurred in 2006 (19.55/100,000 inhabitants). This finding was confirmed by the time series analysis, which also showed a positive tendency over the period analyzed. The present study allows us to conclude that the disease was clustered in the Southwest side of the city in 2006, suggesting that this area may require special attention with regard to control and prevention measures.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Luiz Euribel Prestes-Carneiro ◽  
Patricia Rodrigues Naufal Spir ◽  
Mateus Fontanesi ◽  
Karen Gabriella Pereira Garcia ◽  
Francisco Assis da Silva ◽  
...  

2021 ◽  
Vol 15 (11) ◽  
pp. 1661-1669
Author(s):  
Juliane De Almeida Crispim ◽  
Luiz Henrique Arroyo ◽  
Thaís Zamboni Berra ◽  
Felipe Lima dos Santos ◽  
Ludmilla Leidianne Limirio Souza ◽  
...  

Introduction: Prisons are high-risk settings for drug-resistant tuberculosis because the prevalence of the tuberculosis (TB) is much higher than in the general population. This study to investigated the factors associated with drug-resistant tuberculosis in prisons in the state of São Paulo, Brazil. Methodology: Retrospective cohort of drug-resistant TB cases for incarcerated people in São Paulo state, reported in the Tuberculosis Patient Control System between 2006 and 2016. To analyze the factors associated with drug-resistant TB, the backward method (likelihood ratio) was used, determining the adjusted odds ratio and respective 95%CI coefficients. Multiple models were proposed to adjust for potential confusion and interaction. The best fit model was selected based on the lowest Akaike information criterion coefficient. Results: In total, 473 drug-resistant tuberculosis cases were reported in the prison population of Sāo Paulo state, the majority were male. The cases that presented negative results for sputum smear and sputum culture had, respectively, an aOR=0.6 and aOR=0.16 for drug-resistant tuberculosis in relation to the cases with positive results. The cases where the patient had AIDS and reported alcoholism, respectively, an aOR=1.47 and aOR=1.60 for drug-resistant TB. Individuals with a background treatment history for TB presented a stronger association with drug-resistant tuberculosis, aOR=35.08. Conclusions: Sputum spear, sputum culture, chest X-ray, AIDS, alcoholism and background treatment history for TB were factors associated with resistance to antituberculosis drugs among prisoners. This is useful for the implementation of disease control measures related to the detection and monitoring of cases in the prison system.


2020 ◽  
Vol 95 ◽  
pp. 44-49
Author(s):  
José Cláudio Simão ◽  
Cassiano Victória ◽  
Carlos Magno Castelo Branco Fortaleza

Author(s):  
Eduardo Alexandre Rancan ◽  
Eduardo Federighi Baisi Chagas ◽  
Márcia Aparecida Sperança ◽  
Valeria Camargo de Lacerda Carvalho ◽  
Luciamáre Perinetti Alves Martins ◽  
...  

2008 ◽  
Vol 357 (3-4) ◽  
pp. 153-173 ◽  
Author(s):  
Vanessa Madrucci ◽  
Fabio Taioli ◽  
Carlos César de Araújo

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