scholarly journals Bipolar Disorder: Clinical Perspectives and Implications with Cognitive Dysfunction and Dementia

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
R. Lopes ◽  
L. Fernandes
Keyword(s):  
Bipolar Disorder ◽  
Cognitive Dysfunction ◽  
Verbal Memory ◽  
English Language ◽  
Bipolar Affective Disorder ◽  
Affective Symptoms ◽  
Neurocognitive Evaluation ◽  
Near Future ◽  
A Current ◽  
Organic Dementia

Introduction. Cognitive dysfunction as a core feature in the course of bipolar affective disorder (BPD) is a current subject of debate and represents an important source of psychosocial and functional burden.Objectives. To stand out the connection and clinical implications between cognitive dysfunction, dementia, and BPD.Methods. A nonsystematic review of all English language PubMed articles published between 1995 and 2011 using the terms “bipolar disorder,” “cognitive dysfunction,” and “dementia”.Discussion. As a manifestation of an affective trait or stage, both in the acute phases and in remission, the domains affected include attention, executive function, and verbal memory. The likely evolution or overlap with the behavioural symptoms of an organic dementia allows it to be considered as a dementia specific to BPD. This is named by some authors, as BPD type VI, but others consider it a form of frontotemporal dementia. It is still not known if this process is neurodevelopmental or neurodegenerative in nature, or both simultaneously. The assessment should consider the iatrogenic effects of medication, the affective symptoms, and a neurocognitive evaluation.Conclusion. More specific neuropsychological tests and functional imaging studies are needed and will assume an important role in the near future for diagnosis and treatment.

scholarly journals Considerations on assisted resilience and individualized therapy in bipolar affective disorder, with a clinical case exemplification

2015 ◽  
Vol 88 (4) ◽  
pp. 462-467 ◽  
Author(s):  
Alexandra Bolos
Keyword(s):  
Bipolar Disorder ◽  
Affective Disorder ◽  
Clinical Case ◽  
Bipolar Affective Disorder ◽  
Indirect Costs ◽  
Economic Consequences ◽  
Case Presentation ◽  
Affective Symptoms ◽  
Psychosocial Consequences

Morbidity, mortality and economic consequences of bipolar affective disorder are very important to be evaluated because many of the costs entailed by this psychiatric disorder come from indirect costs due to inadequate diagnosis and treatment and from the characteristics of the affective symptoms itself. Psychotherapy focuses on diagnosis and the newest pharmacotherapy determines a decreasing of the morbidity of the disorder and also of its social and economic burden . However, more studies are necessary, with more heterogeneous patients, to find more predictors regarding the psychosocial consequences and to find more information about the prognosis of the bipolar disorder.In this context, in this paper we discuss the role of assisted resilience and the individualization of the therapy of bipolar affective disorder, especially that the resilience must be seen as a continuum and can be used anytime and in any situation, according to the theory of Geanellos. This idea is reflected in a case presentation of a patient with the diagnosis of bipolar disorder.

Euthymic bipolar disorder: Are there cognitive dysfunctions?

2011 ◽  
Vol 26 (S2) ◽  
pp. 198-198
Author(s):  
G. Da Ponte ◽  
T. Neves ◽  
M. Lobo
Keyword(s):  
Bipolar Disorder ◽  
Executive Functions ◽  
Cognitive Dysfunction ◽  
Cognitive Deficits ◽  
Verbal Memory ◽  
Clinical Case ◽  
Relevant Literature ◽  
Psychological Tests ◽  
Drug Treatments ◽  
Depressive Episodes

IntroductionThe presence of cognitive dysfunction in bipolar disorder is well established, but in the euthymic phase appear a few studies that point to the absence of cognitive deficits.ObjectivesAlert to cases of euthymic bipolar disorder with no cognitive dysfunction.MethodsReview of relevant literature and description of a clinical case with psychological tests that assess memory and executive functions.ResultsDescription of a clinical case: FP is a middle age woman, early retired, with a bipolar disorder type 2, which begins at age 30.Her disease has several depressive episodes, and in the last 10 years, she spent most of the days lying in bed and repeatedly resorted to the emergency department for excessive voluntary drug intoxication or simply because she “wanted” to be hospitalized; her husband could not stand this situation. In September of 2009, in addition to the medical and psychological consultations, she starts attending group therapy; over the next 6 months her medication was changed and finally her disease goes into remission.The psychological tests, made at euthymic phase, show’s no significant deficits in verbal memory and executive functions.ConclusionsThis patient has a disease with prolonged course and multiple hospitalizations and drug treatments, but don’t present relevant cognitive deficits, which may point to the fact that cognitive impairment is determined by biological factors.

P01-223-Recovery of cognitive functioning in patients with co-occurring bipolar disorder and alcohol dependence during early remission from an acute mood episode

2011 ◽  
Vol 26 (S2) ◽  
pp. 224-224
Author(s):  
B. Levy ◽  
E. Manove ◽  
R. Weiss
Keyword(s):  
Bipolar Disorder ◽  
Alcohol Dependence ◽  
Cognitive Functioning ◽  
Cognitive Dysfunction ◽  
Verbal Memory ◽  
Visual Memory ◽  
Longitudinal Design ◽  
Dually Diagnosed ◽  
Mood Episode

IntroductionPreliminary data suggest that patients who suffer from both bipolar disorder (BD) and alcohol dependence (AD) may be more vulnerable to cognitive dysfunction than patients with a single diagnosis, especially during periods that are clinically unstable.ObjectiveThe purpose of this study was to examine the cognitive recovery of dually-diagnosed patients during remission from an acute mood disturbance.AimThe study aimed to replicate our previous comparison of cognitive functioning between BD patients with and without AD, while on the inpatient unit, and to extend this investigation in a longitudinal design post-discharge.MethodFifty-five adult inpatients with bipolar I disorder completed a neuropsychological battery, mood measures and substance abuse measures upon discharge from the hospital and at a 3 month follow up. Analyses provided group comparisons on these measures between patients who presented with co-occurrence of AD (n = 21) in the year prior to hospital admission and patients without a Substance Use Disorder (SUD; n = 34).ResultsCompared to patients without SUD, dually-diagnosed patients scored significantly more poorly on measures of visual memory, verbal memory and executive functioning both at hospital discharge and follow-up. They also exhibited more limited recovery of these functions over the course of this period. Mood symptoms decreased in both groups from discharge to follow up.ConclusionsPatients with co-occurring BD and AD may suffer from more severe cognitive dysfunction and less favorable recovery of cognitive deficits than BD patients without SUD over the course of remission from a mood episode.

A Case Report of a Woman with Premenstrual Dysphoric Disorder Misdiagnosed as Having Bipolar Affective Disorder

2020 ◽  
Vol 13 (2) ◽  
pp. 144-146
Author(s):  
Rossitza K. Iakimova ◽  
Maya Y. Stoimenova-Popova ◽  
Petranka G. Chumpalova ◽  
Milena S. Pandova ◽  
Maria B. Stoyanova
Keyword(s):  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Case Report ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Correct Diagnosis ◽  
Premenstrual Dysphoric Disorder ◽  
Mood Changes ◽  
Affective Symptoms

Summary Frequent mood changes are found in premenstrual dysphoric disorder (PMDD) as well as in bipolar affective disorder (BAD). The differential diagnosis is difficult because both conditions share some other common symptoms. We present a case study of a woman with premenstrual dysphoric disorder misdiagnosed as bipolar disorder. As a result, the patient was prescribed lithium and remained symptomatic for a prolonged period. She recovered only after initiation of treatment with a selective serotonin reuptake inhibitor, which is the treatment of choice in the management of PMDD. In such cases, the importance of affective symptoms evaluation is underscored in the context of the menstrual cycle, as well as in recognizing them for the correct diagnosis and treatment.

Sustained attention deficit in bipolar disorder

2002 ◽  
Vol 180 (4) ◽  
pp. 313-319 ◽  
Author(s):  
Luke Clark ◽  
Susan D. Iversen ◽  
Guy M. Goodwin
Keyword(s):  
Bipolar Disorder ◽  
Sustained Attention ◽  
Attention Deficit ◽  
Verbal Memory ◽  
Neuropsychological Functioning ◽  
Attentional Set ◽  
Illness Onset ◽  
Affective Symptoms ◽  
Attentional Set Shifting ◽  
Neuropsychological Tasks

BackgroundRecovery in bipolar disorder is central to its definition but is rarely complete. Previous work has suggested that neuropsychological impairment persists during the euthymic state but has been confounded partly by mild affective symptoms in remitted patients.AimsTo characterise neuropsychological functioning in the euthymic phase of bipolar disorder with an emphasis on tasks of executive functioning.MethodThirty euthymic patients with bipolar disorder were compared with thirty healthy controls on neuropsychological tasks differentially sensitive to damage within prefrontal cortex.ResultsBipolar I patients were impaired on tasks of attentional set shifting, verbal memory and sustained attention. Only sustained attention deficit survived controlling for mild affective symptoms. This deficit was related to progression of illness, but was none the less present in a subgroup of patients near illness onset.ConclusionsSustained attention deficit may represent a neuropsychological vulnerability marker for bipolar disorder, providing a focus for further understanding of the phenotype and analysis of the neuronal networks involved.

ADOECIMENTO DE PROFESSORES UNIVERSITÁRIOS COM DIAGNÓSTICO DE TRANSTORNO AFETIVO BIPOLAR UMA REVISÃO DE LITERATURA

REVISTA FIMCA ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 1-6
Author(s):  
Pâmela Gomes Artioli ◽  
Natiely Souza Lima ◽  
Camila Silva
Keyword(s):  
Higher Education ◽  
Bipolar Disorder ◽  
Bipolar Affective Disorder ◽  
Physical Work ◽  
Education Professionals ◽  
Work Related ◽  
Analysis Technique ◽  
Work Routine ◽  
Teaching Area

Introdução: Com o passar dos anos, além de doenças laborais físicas, surge um novo cenário de doenças emocionais que vem afetando gradativamente profissionais da área da docência a pesquisa em questão visou identificar os transtornos mentais que mais provocam afastamento de docentes em instituições de ensino superior, (com ênfase no transtorno bipolar), onde contribuiu para se aprofundar a análise de fatores relacionados a esse tipo de transtorno. Objetivos: os objetivos deste estudo, são de realizar análise crática e reflexiva quanto ao número elevado de professores de ensino superior com o Transtorno Afetivo Bipolar, e a relação dos fatores associados a este impedimento dos profissionais, destacar também questões relativas à saúde mental, e identificar quais são as consequências que implicam na rotina de trabalho desses professores e o aumento de docentes com diagno?stico de Transtorno Bipolar. Materiais e Métodos: Quanto à fundamentação teórica, trata-se de um referencial bibliográfico ao passo que utiliza de literaturas científicas disponibilizadas por meio eletrônico. Utilizando-se como técnica de análise de dados a análise de conteúdo interpretativa. Os critérios de inclusão que foram usados são: publicações em português, entre os anos de 2000 a 2018 disponíveis na íntegra. Conclusão: Por fim chegou-se ao entendimento de que além da sobrecarga os docentes remanescentes, o adoecimento crescente dos profissionais da educação compromete a qualidade de vida desses profissionais. Introduction: Over the years, in addition to physical work-related illnesses, a new scenario of emotional diseases emerges that has gradually affected professionals in the teaching area. The research in question aimed at identifying the mental disorders that cause the most withdrawal of teachers in higher education institutions, (with emphasis on bipolar disorder), where it contributed to deepen the analysis of factors related to this type of disorder. Objectives: The objectives of this study are to perform a critical and reflexive analysis regarding the high number of teachers of higher education with Bipolar Affective Disorder, and the relation of the factors associated with this impediment of the professionals, also highlight issues related to mental health, and identify what are the consequences that imply in the work routine of these teachers and the increase of teachers diagnosed with Bipolar Disorder. Materials and Methods: Regarding the theoretical basis, it is a bibliographical reference while using scientific literatures made available electronically. The analysis of interpretive content was used as data analysis technique. The inclusion criteria that were used are: publications in Portuguese, between the years 2000 to 2018 available in full. Conclusion: Finally, it was understood that in addition to overloading the remaining teachers, the growing sickness of education professionals compromises the quality of life of these professionals.

Metabolic syndrome in subjects with bipolar disorder and major depressive disorder in a current depressive episode: Population-based study

2017 ◽  
Vol 92 ◽  
pp. 119-123 ◽  
Author(s):  
Fernanda Pedrotti Moreira ◽  
Karen Jansen ◽  
Taiane de Azevedo Cardoso ◽  
Thaíse Campos Mondin ◽  
Pedro Vieira da Silva Magalhães ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Bipolar Disorder ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Depressive Episode ◽  
Population Based ◽  
Major Depressive ◽  
Population Based Study ◽  
A Current

Who Responds to Prophylactic Lithium Therapy?

1993 ◽  
Vol 163 (S21) ◽  
pp. 20-26 ◽  
Author(s):  
M. T. Abou-Saleh
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Bipolar Affective Disorder ◽  
Positive Family History ◽  
Specific Treatment ◽  
Predictors Of Outcome ◽  
Powerful Predictor ◽  
Bipolar Illness ◽  
History Of ◽  
Psychotic Features

The search for predictors of outcome has not been particularly rewarding, and the use of lithium remains empirical: a trial of lithium is the most powerful predictor of outcome. However, lithium is a highly specific treatment for bipolar disorder. In non-bipolar affective disorder, factors of interest are correlates of bipolar disorder: mood-congruent psychotic features, retarded-endogenous profile, cyclothymic personality, positive family history of bipolar illness, periodicity, and normality between episodes of illness.

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