scholarly journals Linkage of Multiple Sclerosis and Guillain-Barre Syndrome: A Population-Based Survey in Isfahan, Iran

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Masoud Etemadifar ◽  
Peyman Roomizadeh ◽  
Seyed-Hossein Abtahi ◽  
Sepideh Sajjadi ◽  
Amin Abedini ◽  
...  

Background. Multiple Sclerosis (MS) and Guillain Barre Syndrome (GBS) are autoimmune demyelinating disorders of Central and Peripheral Nervous system, respectively. The coexistence of these two syndromes in an individual's life span is rare.Objectives. To inspect throughout Isfahan MS society (IMSS) records for MS cases who had history of documented GBS whether before the onset of MS or after it.Methods. This retrospective survey was carried out by analyzing the clinical records of 3,522 MS patients who were registered with IMSS, from April 2003 to July 2010. Eligible cases were requested to attend to IMSS for final clinical/paraclinical examinations.Results. Among 3,522 (2,716 women and 806 men) MS subjects, we could identify seven patients (six females and one male) with documented diagnosis of GBS. Six patients (five women and one man) had developed MS within6.5±7.0(range: 1–16) years after being diagnosed with GBS and one (a woman) had developed GBS three years after the diagnosis of MS.Conclusion. It seems that the development of MS in individuals with history of GBS is more than a simple incidental event.

2021 ◽  
pp. 1-5
Author(s):  
Amr Hassan ◽  
Alaa El-Mazny ◽  
Mohammed Saher ◽  
Ismail Ibrahim Ismail ◽  
Mohammed Almuqbil

Guillain-Barre syndrome (GBS) and multiple sclerosis (MS) are autoimmune demyelinating disorders of the peripheral and central nervous systems, respectively. The co-occurrence of these 2 conditions is rare in the literature. Herein, we present a rare case of GBS and MS in a 19-year-old female who presented initially with GBS followed by MS, and we provide a literature review. Despite being rare, it should be kept in mind in the differential diagnosis of patients with atypical and usual presentation of both diseases.


2018 ◽  
Vol 266 (2) ◽  
pp. 440-449 ◽  
Author(s):  
Helle Al-Hakem ◽  
Søren H. Sindrup ◽  
Henning Andersen ◽  
Charlotte Dornonville de la Cour ◽  
Lisbeth L. Lassen ◽  
...  

2017 ◽  
Vol 37 ◽  
pp. 19-23 ◽  
Author(s):  
Arturo Arias ◽  
Lilian Torres-Tobar ◽  
Gualberto Hernández ◽  
Deyanira Paipilla ◽  
Eduardo Palacios ◽  
...  

2019 ◽  
Vol 12 (4) ◽  
pp. e226925 ◽  
Author(s):  
Preet Mukesh Shah ◽  
Vijay Waman Dhakre ◽  
Ramya Veerasuri ◽  
Anand Bhabhor

A 56-year-old woman with a medical history of hypertension presented to our hospital with back pain, abdominal pain, vomiting and elevated blood pressure. The laboratory parameters including evaluation for secondary hypertension were within normal ranges at the time of presentation. During her hospitalisation, fluctuations in her blood pressure and pulse were observed which were attributed to autonomic disturbances, the cause of which was unknown. On the seventh day after presentation to the hospital, the patient developed focal seizures and slurred speech which was believed to be secondary to hyponatraemia detected at that time. Hyponatraemia improved with hypertonic saline and she experienced no further seizures. On the eighth day of her admission, she developed acute flaccid paralysis of all her limbs and respiratory distress. We concluded this to be secondary to Guillain-Barre syndrome (GBS). She responded to plasmapheresis.The presence of dysautonomia and hyponatraemia before the onset of paralysis makes this a rare presentation of GBS.


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