scholarly journals Peyronie’s Disease: Still a Surgical Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Daniel Martinez ◽  
Cesar E. Ercole ◽  
Tariq S. Hakky ◽  
Andrew Kramer ◽  
Rafael Carrion
Keyword(s):  
Tunica Albuginea ◽  
Surgical Techniques ◽  
Clinical Manifestations ◽  
Peyronie’S Disease ◽  
Morbid Condition ◽  
Surgical Disease ◽  
Peyronie's Disease ◽  
The Common ◽  
Clinically Significant ◽  
Morphologic Changes

Peyronie’s Disease (PD) remains a challenging and clinically significant morbid condition. Since its first description by François Gigot de la Peyronie, much of the treatment for PD remains nonstandardized. PD is characterized by the formation of fibrous plaques at the level of the tunica albuginea. Clinical manifestations include morphologic changes, such as curvatures and hourglass deformities. Here, we review the common surgical techniques for the management of patients with PD.

scholarly journals Peyronie's Disease: Evolving Surgical Management and the Role of Phosphodiesterase 5 Inhibitors

2009 ◽  
Vol 9 ◽  
pp. 822-845 ◽  
Author(s):  
Tariq F. Al-Shaiji ◽  
Gerald B. Brock
Keyword(s):  
Tunica Albuginea ◽  
Surgical Techniques ◽  
Peyronie’S Disease ◽  
Surgical Approaches ◽  
Penile Curvature ◽  
Advantages And Disadvantages ◽  
Phosphodiesterase 5 Inhibitors ◽  
Peyronie's Disease ◽  
Phosphodiesterase 5

Peyronie's disease (PD) is a fibrotic disorder of the tunica albuginea of the penis. It is characterized by different degrees of penile curvature and sexual dysfunction. Several medical treatments have been employed to manage the disorder, with variable success rates. Surgical therapy is reserved for patients with severe penile deformity that fails to improve with medical treatment and impedes coital function. The advantages and disadvantages of various surgical approaches have long been debated. Herein, we describe the evolving surgical techniques for PD using knowledge obtained from the contemporary literature. In addition, we discuss the emerging data regarding the role of phosphodiesterase 5 inhibitors in the management of PD.

scholarly journals Recent surgical advances in Peyronie’s Disease

2016 ◽  
Vol 29 (2) ◽  
pp. 131 ◽  
Author(s):  
Sandro Gaspar ◽  
José Santos Dias ◽  
Francisco Martins ◽  
Tomé Lopes
Keyword(s):  
Surgical Management ◽  
Tunica Albuginea ◽  
Surgical Techniques ◽  
Peyronie’S Disease ◽  
Sexual Life ◽  
Surgical Reconstruction ◽  
Management Technique ◽  
Disease Etiology ◽  
Peyronie's Disease ◽  
The Subject

<p><strong>Introduction:</strong> Peyronie’s disease, a fibrotic disorder of the tunica albuginea of the penis, has been associated with penile shortening and some degree of erectile dysfunction. It affects patient’s quality of life, leading to severe psychological, mental, and physical stress. Penile deformation hampers sexual life leading to depression, lack of sexual confidence, loss of sexual function and performance anxiety. Peyronie’s disease etiology is yet to be known. <br /><strong>Material and Methods:</strong> Literature search was conducted in Medline, Embase, and Cochrane databases in January 2015 in order to identify papers related to Peyronie’s disease, concerning evolving surgical management, technique, outcomes as well as ancillary treatments. Publications not concerning humans were not considered. We identified original articles, review articles, and editorials addressing the subject. All articles published in the English language were selected for screening. The eligibility criteria for inclusion were based on relevance concerning the subject. <br /><strong>Results:</strong> The variety of penile deformities associated with Peyronie’s disease still doesn’t have an effective and reliable non-surgical therapy. We summarize the updated surgical techniques and management algorithm described for Peyronie’s disease. <br /><strong>Discussion:</strong> Surgical management shares similar goals: correcting the curvature, preserving erectile function and penile length, and minimizing morbidity.<br /><strong>Conclusion:</strong> To date there is no high level of evidence-based data to determine the best surgical treatment of Peyronie’s disease. After proper diagnosis, surgical reconstruction should be based on giving a functional penis, that is, rectifying the penis with rigidity enough to enable sexual intercourse.</p><p> </p>

Initial experience in the treatment of Peyronie’s disease using testicular vaginal tunica graft

2021 ◽  
pp. 205141582110166
Author(s):  
Rico Luis ◽  
Villasante Nicolás ◽  
Blas Leandro ◽  
Bonnano Nicolás ◽  
Ameri Carlos
Keyword(s):  
Sexual Function ◽  
Tunica Albuginea ◽  
Peyronie’S Disease ◽  
Sexual Life ◽  
Rank Test ◽  
Penile Curvature ◽  
Initial Experience ◽  
Level Of Evidence ◽  
Paired Samples ◽  
Peyronie's Disease

Background: Peyronie’s disease (PD) is a progressive disorder of the connective tissue of the tunica albuginea of the penis that produces an abnormal curvature, painful erections and different degrees of erectile dysfunction (ED). The aim of this study is to evaluate our initial experience in the surgical treatment of PD using an autologous graft of testicular vaginal tunica. Materials and methods: A retrospective study of 23 patients was carried out between 2015 and 2019. The successful surgical stretching rate was defined as a functional 20 degrees of curvature or less. Postoperative sexual function and complications rate were evaluated as secondary objectives. We used the abbreviated IIEF-5 questionnaire and evaluated the sexual function before and after the surgical procedure. Wilcoxon signed-rank test for paired samples (U test) was used, considering a value of p<0.05 to be statistically significant. Results: Only one patient presented a recurrence of the penile curvature, resulting in a 95.6% success rate of functional stretching. We observed a 1.6 and 0.9 difference between pre- and postoperative total score and satisfaction ( p = 0.002 and p = 0.003 respectively) Conclusion: In this series, the use of testicular vaginal tunic was found to be safe and effective with a significant change in the quality of sexual life, especially reflected in the overall satisfaction after the procedure and a low rate of complications. Level of evidence: Not applicable for this multicentre audit.

The use of Dimexide in the complex treatment of Peyronie's disease

1980 ◽  
Vol 61 (6) ◽  
pp. 53-54
Author(s):  
M. G. Muhamadeev ◽  
M. P. Trofimova
Keyword(s):  
Clinical Manifestations ◽  
Disease Recurrence ◽  
Peyronie’S Disease ◽  
Long Term Results ◽  
Complex Treatment ◽  
Results Of Treatment ◽  
Peyronie's Disease

We observed 9 patients with plastic induration of the penis (Peyronie's disease), 3 of them interrupted treatment. Long-term results of treatment were traced in 6 patients (age - from 48 to 60 years): in 5 patients, complaints and clinical manifestations of disease recurrence were not noted for 2-4 years.

Surgical Treatment of Peyronie’s Disease: Systematic Review of Techniques Involving or Not Tunica Albuginea Incision

2020 ◽  
Vol 8 (2) ◽  
pp. 324-332 ◽  
Author(s):  
Alan R.G. Barbosa ◽  
Lucas S. Takemura ◽  
Jonathan D. Cha ◽  
Arie Carneiro ◽  
Gustavo C. Lemos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Treatment ◽  
Tunica Albuginea ◽  
Peyronie’S Disease ◽  
Peyronie's Disease

Surgical Techniques for Difficult and Complicated Cases of Peyronie’s Disease

2015 ◽  
pp. 149-158
Author(s):  
Luigi Rolle ◽  
Carlo Ceruti ◽  
Massimiliano Timpano ◽  
Omid Sedigh ◽  
Marco Falcone ◽  
...  
Keyword(s):  
Surgical Techniques ◽  
Peyronie’S Disease ◽  
Peyronie's Disease

A clinico-aetiological and ultrasonographic study of Peyronie's disease

Sexual Health ◽  
2006 ◽  
Vol 3 (2) ◽  
pp. 113 ◽  
Author(s):  
Bhushan Kumar ◽  
Tarun Narang ◽  
Somesh Gupta ◽  
Madhu Gulati
Keyword(s):  
Clinical Presentation ◽  
Clinical Symptoms ◽  
Tunica Albuginea ◽  
Connective Tissue Disorder ◽  
Peyronie’S Disease ◽  
Penile Curvature ◽  
Age Group ◽  
History Of ◽  
Peyronie's Disease ◽  
Symptoms And Signs

Background: Peyronie’s disease is a localised connective tissue disorder that involves the tunica albuginea of the penis. Although long recognised as an important clinical entity of the male genitalia, the aetiology of this disease has remained poorly understood. Methods: The epidemiology and clinical presentation of Peyronie’s disease during a 10-year period was evaluated. Results: Forty-two men with Peyronie’s disease from Chandigarh, India were reviewed retrospectively. The prevalence of Peyronie’s patients was 1.97/1000 patients. Their ages ranged from 23 to 70 years. Most of them presented during the early phase of the disease. The most common presenting complaint was penile curvature in 34 (80.95%) followed by pain on erection in 28 (66.66%). History of penile trauma was revealed by four (9.52%) patients. Among the risk factors, hypercholesterolemia (60%), hypertension (33.3%) and asymptomatic hyperuricemia (28.34%) were the most common. Twenty-two patients with Peyronie’s disease were studied by ultrasonography. Ultrasonogram was more accurate than clinical assessment in delineating the extent of lesions. In one-third of the patients, sonography demonstrated the plaques to be more extensive than had been detected by clinical examination. Conclusions: The clinical symptoms and signs in our study were, in general, similar to those found in the previous studies. Higher incidence of hypertension and diabetes in patients with Peyronie’s disease may also be to an extent due to patients being in an older age group.

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