scholarly journals Double Bolus Application in TWIST-MR-Angiography of the Cervical Arteries

2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Andreas Korn ◽  
Michael Fenchel ◽  
Till-Karsten Hauser ◽  
Sotirios Bisdas ◽  
Thomas Nägele ◽  
...  
Keyword(s):  
Image Quality ◽  
Mr Angiography ◽  
Bolus Injection ◽  
Diagnostic Image Quality ◽  
Diagnostic Image ◽  
Voxel Size ◽  
Time Resolved ◽  
Injection Protocol ◽  
Quality Rating ◽  
Image Quality Rating

Purpose. The aim of the present work was to test the feasibility of the time-resolved MR-angiography (TWIST-MRA) of cervical arteries using double bolus injection.Material and Methods. TWIST-MRA with a temporal resolution of 8.4 seconds for each frame and a spatial resolution with a voxel size of   was performed in 24 patients. A biphasic bolus injection protocol was used with the second injection being started 21 seconds after the first contrast dye bolus. Diagnostic image quality was rated according to a 4-point scale.Results. In 12 patients (50%) no clear separation between the cervical venous and arterial vessels was evident after the first bolus injection. Using TWIST-MRA data acquired after the second bolus a sufficient diagnostic image quality (rating , mean 3.5) could be obtained in 22 of 24 patients (92%).Discussion. The double bolus injection protocol using TWIST-MRA allows for very good separation of the cervical arteries.

scholarly journals Effect on diagnostic image quality of 3D warping registration algorithms for MR angiography in the lower legs

2012 ◽  
Vol 28 (4) ◽  
pp. 335
Author(s):  
Andrew J. Fagan ◽  
Daniel Foley ◽  
Jacinta E. Browne ◽  
Barry Sheane ◽  
Dearbhail O'Driscoll ◽  
...  
Keyword(s):  
Image Quality ◽  
Mr Angiography ◽  
Diagnostic Image Quality ◽  
Diagnostic Image

Minimizing table time in patients with claustrophobia using focused ferumoxytol-enhanced MR angiography (f-FEMRA): a feasibility study

2021 ◽  
Vol 94 (1125) ◽  
pp. 20210430
Author(s):  
Puja Shahrouki ◽  
Kim-Lien Nguyen ◽  
John M. Moriarty ◽  
Adam N. Plotnik ◽  
Takegawa Yoshida ◽  
...  
Keyword(s):  
Image Quality ◽  
Mr Angiography ◽  
Signal To Noise Ratio ◽  
Diagnostic Image Quality ◽  
Diagnostic Confidence ◽  
Motion Artefact ◽  
Scan Time ◽  
Wilcoxon Rank Sum Test ◽  
Significant Difference ◽  
Noise Ratio

Objectives: To assess the feasibility of a rapid, focused ferumoxytol-enhanced MR angiography (f-FEMRA) protocol in patients with claustrophobia. Methods: In this retrospective study, 13 patients with claustrophobia expressed reluctance to undergo conventional MR angiography, but agreed to a trial of up to 10 min in the scanner bore and underwent f-FEMRA. Thirteen matched control patients who underwent gadolinium-enhanced MR angiography (GEMRA) were identified for comparison of diagnostic image quality. For f-FEMRA, the time from localizer image acquisition to completion of the angiographic acquisition was measured. Two radiologists independently scored images on both f-FEMRA and GEMRA for arterial and venous image quality, motion artefact and diagnostic confidence using a 5-point scale, five being best. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in the aorta and IVC were measured. The Wilcoxon rank-sum test, one-way ANOVA with Tukey correction and two-tailed t tests were utilized for statistical analyses. Results: All scans were diagnostic and assessed with high confidence (scores ≥ 4). Average scan time for f-FEMRA was 6.27 min (range 3.56 to 10.12 min), with no significant difference between f-FEMRA and GEMRA in diagnostic confidence (4.86 ± 0.24 vs 4.69 ± 0.25, p = 0.13), arterial image quality (4.62 ± 0.57 vs 4.65 ± 0.49, p = 0.78) and motion artefact score (4.58 ± 0.49 vs 4.58 ± 0.28, p > 0.99). f-FEMRA scored significantly better for venous image quality than GEMRA (4.62 ± 0.42 vs 4.19 ± 0.56, p = 0.04). CNR in the IVC was significantly higher for steady-state f-FEMRA than GEMRA regardless of the enhancement phase (p < 0.05). Conclusions: Comprehensive vascular MR imaging of the thorax, abdomen and pelvis can be completed in as little as 5 min within the magnet bore using f-FEMRA, facilitating acceptance by patients with claustrophobia and streamlining workflow. Advances in knowledge: A focused approach to vascular imaging with ferumoxytol can be performed in patients with claustrophobia, limiting time in the magnet bore to 10 min or less, while acquiring fully diagnostic images of the thorax, abdomen and pelvis.

scholarly journals Contrast-Enhanced Magnetic Resonance Angiography Using a Novel Elastin-Specific Molecular Probe in an Experimental Animal Model

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Carolin Reimann ◽  
Julia Brangsch ◽  
Jan Ole Kaufmann ◽  
Lisa C. Adams ◽  
David C. Onthank ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Image Quality ◽  
Magnetic Resonance Angiography ◽  
Contrast Agent ◽  
Mr Angiography ◽  
Molecular Probe ◽  
Time Resolved ◽  
Clinical Dose ◽  
Contrast Enhanced ◽  
First Pass

Objectives. The aim of this study was to test the potential of a new elastin-specific molecular agent for the performance of contrast-enhanced first-pass and 3D magnetic resonance angiography (MRA), compared to a clinically used extravascular contrast agent (gadobutrol) and based on clinical MR sequences. Materials and Methods. Eight C57BL/6J mice (BL6, male, aged 10 weeks) underwent a contrast-enhanced first-pass and 3D MR angiography (MRA) of the aorta and its main branches. All examinations were on a clinical 3 Tesla MR system (Siemens Healthcare, Erlangen, Germany). The clinical dose of 0.1 mmol/kg was administered in both probes. First, a time-resolved MRA (TWIST) was acquired during the first-pass to assess the arrival and washout of the contrast agent bolus. Subsequently, a high-resolution 3D MRA sequence (3D T1 FLASH) was acquired. Signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) were calculated for all sequences. Results. The elastin-specific MR probe and the extravascular imaging agent (gadobutrol) enable high-quality MR angiograms in all animals. During the first-pass, the probes demonstrated a comparable peak enhancement (300.6 ± 32.9 vs. 288.5 ± 33.1, p>0.05). Following the bolus phase, both agents showed a comparable intravascular enhancement (SNR: 106.7 ± 11 vs. 102.3 ± 5.3; CNR 64.5 ± 7.4 vs. 61.1 ± 7.2, p>0.05). Both agents resulted in a high image quality with no statistical difference (p>0.05). Conclusion. The novel elastin-specific molecular probe enables the performance of first-pass and late 3D MR angiography with an intravascular contrast enhancement and image quality comparable to a clinically used extravascular contrast agent.

scholarly journals Enhancing Patient Experience With Internet Protocol Addressable Digital LED Lighting in Imaging Environments: A Phase I Study (Preprint)

2018 ◽  
Author(s):  
Melanie U Knopp ◽  
Katherine Binzel ◽  
Chadwick L Wright ◽  
Jun Zhang ◽  
Michael V Knopp
Keyword(s):  
Image Quality ◽  
Patient Experience ◽  
Patient Comfort ◽  
Patient Specific ◽  
Diagnostic Image Quality ◽  
Imaging Studies ◽  
Diagnostic Image ◽  
Clinical Imaging ◽  
Ambient Lighting ◽  
Led Lights

BACKGROUND Conventional approaches to improve the quality of clinical patient imaging studies focus predominantly on updating or replacing imaging equipment; however, it is often not considered that patients can also highly influence the diagnostic quality of clinical imaging studies. Patient-specific artifacts can limit the diagnostic image quality, especially when patients are uncomfortable, anxious, or agitated. Imaging facility or environmental conditions can also influence the patient’s comfort and willingness to participate in diagnostic imaging studies, especially when performed in visually unesthetic, anxiety-inducing, and technology-intensive imaging centers. When given the opportunity to change a single aspect of the environmental or imaging facility experience, patients feel much more in control of the otherwise unfamiliar and uncomfortable setting. Incorporating commercial, easily adaptable, ambient lighting products within clinical imaging environments allows patients to individually customize their environment for a more personalized and comfortable experience. OBJECTIVE The aim of this pilot study was to use a customizable colored light-emitting diode (LED) lighting system within a clinical imaging environment and demonstrate the feasibility and initial findings of enabling healthy subjects to customize the ambient lighting and color. Improving the patient experience within clinical imaging environments with patient-preferred ambient lighting and color may improve overall patient comfort, compliance, and participation in the imaging study and indirectly contribute to improving diagnostic image quality. METHODS We installed consumer-based internet protocol addressable LED lights using the ZigBee standard in different PET/CT scan rooms within a clinical imaging environment. We recruited healthy volunteers (n=35) to generate pilot data in order to develop a subsequent clinical trial. The visual perception assessment procedure utilized questionnaires with preprogrammed light/color settings and further assessed how subjects preferred ambient light and color within a clinical imaging setting. RESULTS Technical implementation using programmable LED lights was performed without any hardware or electrical modifications to the existing clinical imaging environment. Subject testing revealed substantial variabilities in color perception; however, clear trends in subject color preference were noted. In terms of the color hue of the imaging environment, 43% (15/35) found blue and 31% (11/35) found yellow to be the most relaxing. Conversely, 69% (24/35) found red, 17% (6/35) found yellow, and 11% (4/35) found green to be the least relaxing. CONCLUSIONS With the majority of subjects indicating that colored lighting within a clinical imaging environment would contribute to an improved patient experience, we predict that enabling patients to customize environmental factors like lighting and color to individual preferences will improve patient comfort and patient satisfaction. Improved patient comfort in clinical imaging environments may also help to minimize patient-specific imaging artifacts that can otherwise limit diagnostic image quality. CLINICALTRIAL ClinicalTrials.gov NCT03456895; https://clinicaltrials.gov/ct2/show/NCT03456895

scholarly journals Artifacts in magnetic resonance imaging: how it can really affect diagnostic image quality and confuse clinical diagnosis?

2018 ◽  
Vol 20 (2) ◽  
pp. 1202-1213 ◽  
Author(s):  
Tomas Budrys ◽  
Vincentas Veikutis ◽  
Saulius Lukosevicius ◽  
Rymante Gleizniene ◽  
Egle Monastyreckiene ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Image Quality ◽  
Clinical Diagnosis ◽  
Diagnostic Image Quality ◽  
Resonance Imaging ◽  
Diagnostic Image

Limits of the possible: diagnostic image quality in coronary angiography with third-generation dual-source CT

2017 ◽  
Vol 106 (7) ◽  
pp. 485-492 ◽  
Author(s):  
Marco M. Ochs ◽  
Fabian aus dem Siepen ◽  
Thomas Fritz ◽  
Florian Andre ◽  
Gitsios Gitsioudis ◽  
...  
Keyword(s):  
Image Quality ◽  
Coronary Angiography ◽  
Diagnostic Image Quality ◽  
Third Generation ◽  
Dual Source Ct ◽  
Diagnostic Image ◽  
Dual Source
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