scholarly journals Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behçet’s Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Rachel Black ◽  
Sue Lester ◽  
Emma Dunstan ◽  
Farhad Shahram ◽  
Abdolhadi Nadji ◽  
...  
Keyword(s):  
Risk Factor ◽  
Copy Number Variation ◽  
Behçet’S Disease ◽  
Copy Number ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Fc Gamma Receptor ◽  
Behcet's Disease ◽  
Gamma Receptor ◽  
Number Variation

HLA-A26 is a risk factor for Behçet’s disease ocular lesions

2020 ◽  
Vol 31 (1) ◽  
pp. 214-218
Author(s):  
Hiroaki Kato ◽  
Masaki Takeuchi ◽  
Nobuyuki Horita ◽  
Takehito Ishido ◽  
Ryuta Mizuki ◽  
...  
Keyword(s):  
Risk Factor ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
Ocular Lesions

scholarly journals MiR-146a and miR-155 polymorphisms in Egyptian patients with Behcet’s disease

2021 ◽  
Author(s):  
Omayma Abdelaleem ◽  
Olfat Shaker
Keyword(s):  
Risk Factor ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Recessive Model ◽  
Additive Models ◽  
Ocular Involvement ◽  
Behcet's Disease ◽  
Egyptian Population ◽  
Egyptian Patients

IntroductionBackground: The current study designed to analyze whether polymorphisms of miR-146a and miR-155 are related to Behçet’s disease (BD) in Egyptian population.Material and methodsMethods: A total of 96 unrelated BD patients and 100 healthy subjects were genotyped for miR-146a (rs2910164) and miR-155(rs767649) using real-time polymerase chain reaction.ResultsResults: the results showed significant elevation in the frequency of rs2910164 GG and CC genotypes in BD patients compared with controls (adjusted OR = 22.156, 95% CI (4.728-103.818); P < 0.001 and adjusted OR = 40.358, 95% CI (8.928 -182.440); P < 0.001, respectively). Also, rs2910164 G allele conferred a higher risk of developing BD (adjusted OR = 3.665, 95% CI (2.013-6.671); P < 0.001). MiR-146a (rs2910164) polymorphism was a risk factor for susceptibility to BD in dominant, recessive and additive models of inheritance(All P < 0.001), while, the miR-155(rs767649) polymorphism was a risk factor in recessive model only (P = 0.021). GG and CG genotypes of rs2910164 were associated with higher BDCAI activity and ocular involvement compared with CC genotype (P = 0.005 and P =0.004, respectively). Genotype AT of rs767649 was related to higher BDCAI activity (P = 0. 026) compared with TT or AA genotypes.ConclusionsConclusion: The miR-146a (rs2910164) and miR-155(rs767649) were likely to play an important role in Egyptian population to develop BD and also influence disease severity.

scholarly journals High lipoprotein (a) levels as a thrombogenic risk factor in Behcet's disease.

1994 ◽  
Vol 53 (5) ◽  
pp. 351-352 ◽  
Author(s):  
A Orem ◽  
O Deger ◽  
O Memis ◽  
K Caliskan ◽  
G Cimsit
Keyword(s):  
Risk Factor ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease ◽  
Lipoprotein A
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