scholarly journals Muscle Invasive Bladder Cancer: From Diagnosis to Survivorship

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
N. E. Mohamed ◽  
M. A. Diefenbach ◽  
H. H. Goltz ◽  
C. T. Lee ◽  
D. Latini ◽  
...  

Bladder cancer is the fifth most commonly diagnosed cancer and the most expensive adult cancer in average healthcare costs incurred per patient in the USA. However, little is known about factors influencing patients' treatment decisions, quality of life, and responses to treatment impairments. The main focus of this paper is to better understand the impact of muscle invasive bladder cancer on patient quality of life and its added implications for primary caregivers and healthcare providers. In this paper, we discuss treatment options, side effects, and challenges that patients and family caregivers face in different phases along the disease trajectory and further identify crucial areas of needed research.

2020 ◽  
Author(s):  
Alexandros Vaioulis ◽  
Konstantinos Bonotis ◽  
Konstantinos Perivoliotis ◽  
Yiannis Kiouvrekis ◽  
Stavros Gavras ◽  
...  

Introduction We evaluated anxiety and quality of life (QoL) in patients who were operated for non-muscle invasive bladder cancer (NMIBC) Methods The present study is a prospective analysis of patients with histopathologically confirmed NMIBCs after they were submitted to transurethral resection of the tumour (TURBT). Eligible were all adult patients with a single or multiple NMIBCs. All included patients followed therapy with either BCG or Epirubicin instillations. The SF-36 questionnaire Physical and Mental health aspects were used for QoL assessment. Similarly, the STAI-Y was introduced for the state (STAI-Y1) and trait anxiety (STAI-Y2) evaluation. Results In total, 117 eligible patients were included. Regarding SF-36 Physical a 6 months decrease was followed by an improvement at 12 months. Similarly, an increase of the SF-36 Mental health score was identified. In contrast to STAI-Y2, a long-term reduction of the state anxiety was identified. Preoperative SF-36 Physical was inversely correlated with age, while absence of alcohol was associated with lower mental health. Overall, patient characteristics, habits and the administered treatment did not affect the postoperative QoL and anxiety. Conclusions Patient QoL and anxiety improved during follow up. Although certain characteristics were related to QoL and anxiety, further larger scale studies are required.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Daniel A. Barocas ◽  
Denise R. Globe ◽  
Danielle C. Colayco ◽  
Ahunna Onyenwenyi ◽  
Amanda S. Bruno ◽  
...  

Seventy percent of newly diagnosed bladder cancers are classified as non-muscle-invasive bladder cancer (NMIBC) and are often associated with high rates of recurrence that require lifelong surveillance. Currently available treatment options for NMIBC are associated with toxicities that limit their use, and actual practice patterns vary depending upon physician and patient characteristics. In addition, bladder cancer has a high economic and humanistic burden in the United States (US) population and has been cited as one of the most costly cancers to treat. An unmet need exists for new treatment options associated with fewer complications, better patient compliance, and decreased healthcare costs. Increased prevention of recurrence through greater adherence to evidence-based guidelines and the development of novel therapies could therefore result in substantial savings to the healthcare system.


2020 ◽  
Vol 38 (6_suppl) ◽  
pp. 462-462
Author(s):  
Hannah McCloskey ◽  
Sean McCabe ◽  
Kathryn Gessner ◽  
Pauline Filippou ◽  
Judy Hamad ◽  
...  

462 Background: Treatment delivery for muscle invasive bladder cancer (MIBC) may involve general urologists, urologic oncologists or a multidisciplinary team that includes medical oncology and radiation oncology. Our objective was to evaluate differences in general and bladder cancer-specific quality of life (QOL) based on treating physician among MIBC patients. Methods: We performed a cross-sectional survey of bladder cancer patients using the Bladder Cancer Advocacy Network Patient Survey Network and Inspire platforms to determine general and bladder cancer-specific QOL using the EORTC QLQ-C30 and Bladder Cancer Index, respectively. Patients were also queried regarding demographic, socioeconomic and clinical characteristics. Patients were asked whether they sought care from a general urologist, urologic oncologist, medical oncologist and/or radiation oncologist. We present descriptive statistics and a multiple linear regression model to identify factors independently associated with QOL domain score. Results: 270 respondents identified as MIBC patients. Among MIBC respondents, 38% were female and 97% were white. The mean age was 67.4 years (range 30 to 93 years). Respondents were highly educated (67% completed college). Among MIBC patients, 17% sought care from a general urologist only, 33% from a urologic oncologist only, and 50% from a multidisciplinary team that included either a medical or radiation oncologist. Physician specialty was not associated with generic, sexual, or bowel QOL. Patients seeing a general urologist had—on average—better urinary function compared with those seeing a urologic oncologist or multidisciplinary team. On multivariable analysis, physician specialty remained a significant predictor of urinary function (p = 0.02), controlling for age, sex, race, recurrence, and comorbidity. Conclusions: Among MIBC patients, physician specialty does not substantially impact general QOL but may be associated with urinary function. This may relate to cancer severity or other unmeasured patient characteristics.


2008 ◽  
Vol 15 (5) ◽  
pp. 403-406 ◽  
Author(s):  
Katsuyoshi Hashine ◽  
Noriyoshi Miura ◽  
Kousaku Numata ◽  
Akitomi Shirato ◽  
Yoshiteru Sumiyoshi ◽  
...  

2019 ◽  
Vol 18 (5) ◽  
pp. e2544
Author(s):  
S. O’Meara ◽  
S. Considine ◽  
S. Anderson ◽  
M. Aboelmagd ◽  
S. Connolly ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document