scholarly journals MEMS-Based Endoscopic Optical Coherence Tomography

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Jingjing Sun ◽  
Huikai Xie
Keyword(s):  
Optical Coherence Tomography ◽  
Cancer Detection ◽  
Early Cancer ◽  
Low Cost ◽  
Optical Coherence ◽  
Internal Organs ◽  
Imaging Results ◽  
Endoscopic Optical Coherence Tomography ◽  
Mems Technology ◽  
Endoscopic Oct

Early cancer detection has been playing an important role in reducing cancer mortality. Optical coherence tomography (OCT), due to its micron-scale resolution, has the ability to detect cancerous tissues at their early stages. For internal organs, endoscopic probes are needed as the penetration depth of OCT is about 1–3 mm. MEMS technology has the advantages of fast speed, small size, and low cost, and it has been widely used as the scanning engine in endoscopic OCT probes. Research results have shown great potential for OCT in endoscopic imaging by incorporating MEMS scanning mirrors. Various MEMS-OCT designs are introduced, and their imaging results are reviewed in the paper.

scholarly journals Stick-slip nonuniform rotation distortion correction in distal scanning optical coherence tomography catheters

2020 ◽  
Vol 13 (06) ◽  
pp. 2050030
Author(s):  
Jessica Mavadia-Shukla ◽  
Jianlin Zhang ◽  
Kaiyan Li ◽  
Xingde Li
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
Distortion Correction ◽  
Rat Colon ◽  
Optical Coherence ◽  
Stick Slip ◽  
Endoscopic Optical Coherence Tomography ◽  
Marker Free ◽  
Endoscopic Oct ◽  
Nonuniform Rotation

We present a robust and fiducial-marker-free algorithm that can identify and correct stick-slip distortion caused by nonuniform rotation (or beam scanning) in distally scanned catheters for endoscopic optical coherence tomography (OCT) images. This algorithm employs spatial frequency analysis to select and remove distortions. We demonstrate the feasibility of this algorithm on images acquired from ex vivo rat colon with a distally scanned DC motor-based endoscope. The proposed algorithm can be applied to general endoscopic OCT images for correcting nonuniform rotation distortion.

INTERPIXEL-SHIFTED ENDOSCOPIC OPTICAL COHERENCE TOMOGRAPHY FOR IN VIVO BLADDER CANCER DIAGNOSIS

2007 ◽  
Vol 07 (01) ◽  
pp. 105-117
Author(s):  
ZHENGUO WANG ◽  
CHRISTOPHER S. D. LEE ◽  
WAYNE C. WALTZER ◽  
ZHIJIA YUAN ◽  
YINGTIAN PAN
Keyword(s):  
Optical Coherence Tomography ◽  
Biological Tissue ◽  
Signal To Noise Ratio ◽  
Transitional Cell ◽  
Axial Direction ◽  
Depth Of Field ◽  
Optical Coherence ◽  
Endoscopic Optical Coherence Tomography ◽  
Endoscopic Oct

An interpixel-shifted spectral imaging technique is applied to MEMS-based spectral-domain endoscopic optical coherence tomography (SDEOCT) to enhance signal-to-noise ratio and effective imaging depth for in vivo imaging diagnosis of biological tissue. To validate the enhancements of pixel-shifted SDEOCT, experimental comparisons are presented to image animal and human bladder architectures in vivo and to diagnose human transitional cell cancers. Preliminary study shows that interpixel shifted SDEOCT not only increases the depth of field of SDOCT but also eliminates excessive artifacts induced by spectral aliasing effect, thus improving image contrast in areas with large depths (e.g. over 1.5 mm). These results suggest that endoscopic OCT equipped with interpixel-shifted spectral camera has the potential to enhance the diagnosis of biological tissue in in vivo settings that require a larger field of view in the axial direction, such as papillary bladder tumors with deep surface irregularities (e.g. asperities or invaginations).

scholarly journals Functional and morphological imaging of the human tympanic membrane with endoscopic optical coherence tomography

2017 ◽  
Vol 3 (2) ◽  
pp. 99-101
Author(s):  
Lars Kirsten ◽  
Joseph Morgenstern ◽  
Mikael Timo Erkkilä ◽  
Martin Schindler ◽  
Jonas Golde ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Tympanic Membrane ◽  
Ex Vivo ◽  
Motion Artifacts ◽  
Optical Coherence ◽  
Promising Tool ◽  
Doppler Oct ◽  
Endoscopic Optical Coherence Tomography ◽  
Endoscopic Oct ◽  
Human Middle Ear

AbstractIn this ex vivo feasibility study, endoscopic structural and functional optical coherence tomography (OCT) imaging with a field of view of 8 mm is presented allowing the inspection of nearly the entire tympanic membrane through the ear canal. The endoscope utilizes a gradient index optics for simultaneous OCT and video endoscopy. Additionally, Doppler-OCT allows the measurement of the tympanic membrane oscillation. Due to the fast image acquisition, only minor motion artifacts have been observed, which don’t affect the image quality. In conclusion, endoscopic OCT is considered as a promising tool for the comprehensive examination of the human middle ear.

scholarly journals Imaging of the human tympanic membrane by endoscopic optical coherence tomography

2018 ◽  
Vol 4 (1) ◽  
pp. 305-308
Author(s):  
Martin Schindler ◽  
Lars Kirsten ◽  
Joseph Morgenstern ◽  
Jonas Golde ◽  
Mikael Erkkilä ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Tympanic Membrane ◽  
Three Dimensional ◽  
Acoustic Stimulation ◽  
Surrounding Tissue ◽  
Optical Coherence ◽  
Doppler Oct ◽  
Endoscopic Optical Coherence Tomography ◽  
Endoscopic Oct ◽  
Working Distance

AbstractEndoscopic optical coherence tomography is a non-invasive and contactless imaging technique based on white light interferometry. It enables high-resolution three-dimensional imaging of scattering tissue up to a depth of about 2 mm. In addition, Doppler-OCT can detect sub-resolution movements. These features can be used to examine the tympanic membrane, the surrounding tissue and nearby areas of the tympanic cavity. For this purpose, we present an endoscopic OCT system, which provides access to the tympanic membrane. The design of the endoscope is based on a gradientindex (GRIN) lens system. This allows a broad field of view and a large working distance. An additional VIS beam path allows visual imaging and orientation inside the auditory canal. Therefore, illumination fibers are attached a round the GRIN-system. The resulting endoscope has a length of 55 mm and a diameter of 3.5 mm. By attaching an earphone and a probe microphone, the oscillation of the tympanic membrane can be measured under acoustic stimulation. With the endoscopic OCT system, we provide an examination tool for the diagnosis of a broad number of diseases like conductive hearing loss.

Compact, low-cost Ti:Al_2O_3 laser for in vivo ultrahigh-resolution optical coherence tomography

2003 ◽  
Vol 28 (11) ◽  
pp. 905 ◽  
Author(s):  
A. Unterhuber ◽  
B. Považay ◽  
B. Hermann ◽  
H. Sattmann ◽  
W. Drexler ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Low Cost ◽  
Optical Coherence ◽  
Ultrahigh Resolution
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