scholarly journals Primary Renal Synovial Sarcoma

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Mehmet Gulum ◽  
Ercan Yeni ◽  
Murat Savas ◽  
Ilyas Ozardali ◽  
Ismail Ozdemir ◽  
...  
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Synovial Sarcoma ◽  
Surgical Resection ◽  
Radical Nephrectomy ◽  
English Literature ◽  
Adolescents And Young Adults ◽  
Renal Masses ◽  
Synovial Sarcomas

Synovial sarcomas are generally deep-seated tumors that most often occur in the proximity of large joints of adolescents and young adults. We describe two cases of primary renal synovial sarcoma that were treated successfully by radical nephrectomy. Synovial sarcoma originating from the kidney is extremely rare and the histogenesis is uncertain. Surgical resection and ifosfamide based chemotherapy are the mainstay for the management of renal synovial sarcoma. Fewer than 40 patients have been described in the English literature. Physicians should be aware of the possibility of malignancy in cystic renal masses and raise the suspicion of synovial sarcoma, especially when patients with renal masses are a young adult.

Monophasic Synovial Sarcoma Arising in the Vulva: A Case Report and Review of the Literature

2008 ◽  
Vol 132 (4) ◽  
pp. 698-702
Author(s):  
Beverly E. White ◽  
Alan Kaplan ◽  
Dolores H. Lopez-Terrada ◽  
Jae Y. Ro ◽  
Robert S. Benjamin ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Soft Tissues ◽  
English Literature ◽  
Review Of The Literature ◽  
First Case ◽  
Additional Surgery ◽  
Synovial Sarcomas ◽  
The Right ◽  
Disease Free ◽  
Vulvar Mass

Abstract Synovial sarcomas most commonly arise in the soft tissue of the extremities. Less commonly, these tumors present in the head and neck, abdominal wall, and other sites. However, synovial sarcoma occurring in the vulvar area is extremely rare. Only 2 previous cases of biphasic synovial sarcoma of the vulva have been reported, but no case of vulvar monophasic synovial sarcoma has been described in the English literature. We report the third case of synovial sarcoma and apparently the first case of monophasic synovial sarcoma arising in soft tissues of the vulva. The patient was a 33-year-old woman who presented for evaluation of a painless vulvar mass. The tumor was located in the deep fibroadipose tissue of the right vulva (6.5 × 4.2 × 3.5 cm). The histology of the lesion was that of a monophasic synovial sarcoma with a hemangiopericytic vascular pattern. A subsequent molecular analysis revealed SYT-SSX2 gene fusion, which confirmed the diagnosis of synovial sarcoma. After an initial wide local excision, the patient developed a recurrence in the right groin and received chemotherapy and additional surgery. The patient is currently disease free, on adjuvant chemotherapy, and being followed up closely.

scholarly journals Behind the Reasons: The Relationship Between Adolescent and Young Adult Mental Health Risk Factors and Exposure to Season One of Netflix’s 13 Reasons Why

2021 ◽  
Vol 3 ◽  
Author(s):  
Jabari Miles Evans ◽  
Alexis R. Lauricella ◽  
Drew P. Cingel ◽  
Davide Cino ◽  
Ellen Ann Wartella
Keyword(s):  
Mental Health ◽  
Young Adults ◽  
Young Adult ◽  
Social Anxiety ◽  
The United States ◽  
Individual Characteristics ◽  
Adolescents And Young Adults ◽  
Adolescent And Young Adult ◽  
Individual Level ◽  
Health Related

With increasing media choice, particularly through the rise of streaming services, it has become more important for empirical research to examine how youth decide which programs to view, particularly when the content focuses on difficult health topics such as suicide. The present study investigated why adolescents and young adults chose to view or not view season 1 of 13 Reasons Why and how individual-level variables related to adolescents’ and young adults’ viewing. Using survey data gathered from a sample of 1,100 adolescents and young adult viewers and non-viewers of the series in the United States, we examined how participants’ resilience, loneliness, and social anxiety related to whether participants viewed the first season or not. Our descriptive results indicate that adolescents who watched the show reported that it accurately depicted the social realities of their age group, they watched it because friends recommended it, and they found the subject matter to be interesting. Non-viewers reported that they chose not to view the show because the nature of the content was upsetting to them. In addition, results demonstrated that participants’ social anxiety and resilience related to participants’ viewing decisions, such that those with higher social anxiety and higher resilience were more likely to report watching season 1. Together, these data suggest that youth make intentional decisions about mental health-related media use in an attempt to choose content that is a good fit for based on individual characteristics.

scholarly journals Underlying Ossification Phenotype in a Murine Model of Metastatic Synovial Sarcoma

2020 ◽  
Vol 21 (7) ◽  
pp. 2636
Author(s):  
Matthew Kirkham ◽  
Austen Kalivas ◽  
Kaniz Fatema ◽  
Sarah Luelling ◽  
Brooke H. Dubansky ◽  
...  
Keyword(s):  
Young Adults ◽  
Mouse Model ◽  
Synovial Sarcoma ◽  
Soft Tissues ◽  
Bone Development ◽  
Survival Rates ◽  
Primary Tumors ◽  
Synovial Sarcomas ◽  
Worse Prognosis ◽  
Genetic Mouse Models

Synovial sarcoma, an uncommon cancer, typically affects young adults. Survival rates range from 36% to 76%, decreasing significantly when metastases are present. Synovial sarcomas form in soft tissues, often near bones, with about 10% demonstrating ossification in the tumor. The literature is inconclusive on whether the presence of ossification portends a worse prognosis. To this end, we analyzed our genetic mouse models of synovial sarcoma to determine the extent of ossification in the tumors and its relationship with morbidity. We noted higher ossification within our metastatic mouse model of synovial sarcoma. Not only did we observe ossification within the tumors at a frequency of 7%, but an even higher frequency, 72%, of bone reactivity was detected by radiography. An enrichment of bone development genes was associated with primary tumors, even in the absence of an ossification phenotype. In spite of the ossification being intricately linked with the metastatic model, the presence of ossification was not associated with a faster or worse morbidity in the mice. Our conclusion is that both metastasis and ossification are dependent on time, but that they are independent of one another.

Putting Adolescents and Young Adults in a Room Together: Launching an Adolescent and Young Adult Oncology Council

2019 ◽  
Vol 8 (5) ◽  
pp. 540-546 ◽  
Author(s):  
Bethann M. Pflugeisen ◽  
Pandora Patterson ◽  
Catherine F. Macpherson ◽  
Bernadette C. Ray ◽  
Rebecca L. Jacobsen ◽  
...  
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Adolescents And Young Adults ◽  
Adolescent And Young Adult ◽  
Young Adult Oncology

Earrings: A Source of Bloodborne Infections?

PEDIATRICS ◽  
1992 ◽  
Vol 90 (6) ◽  
pp. 1005-1005
Author(s):  
PHILIP D. WALSON ◽  
MICHAEL T. BRADY
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Health Risk ◽  
Sexual Activity ◽  
Adolescents And Young Adults ◽  
Bloodborne Infections

To the Editor.— We recently became aware of a practice which has potential for transmission of bloodborne diseases: sharing of nonsterilized earrings. Both young adult-aged children of one of us (P. W.) confided that they had shared earrings with friends. Although both children were aware of the risks associated with the sharing of needles and sexual activity, neither associated sharing earrings with any health risk. Questioning of other adolescents and young adults revealed that this practice may be widespread.

scholarly journals Smoking prevalence, core/periphery network positions, and peer influence: Findings from five datasets on US adolescents and young adults

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248990
Author(s):  
Cheng Wang
Keyword(s):  
Young Adults ◽  
Young Adult ◽  
Peer Influence ◽  
Smoking Prevalence ◽  
Random Network ◽  
Smoking Behavior ◽  
The Other ◽  
Adolescents And Young Adults ◽  
Adolescent And Young Adult ◽  
The Past

Smoking prevalence has decreased significantly among US adolescents and young adults in the past 20 years. It is possible that adolescent and young adult smokers were moving from core to peripheral positions in social networks and thus less influential as suggested in previous research on adult smokers. We construct five sample datasets to test these hypotheses but none of them receives much support. When the proportion of smokers is relatively higher in two sample datasets, smokers tended to be at more marginal network positions than nonsmokers, both smokers and nonsmoker could exert peer influence, and the magnitude of peer influence from smokers was even greater than that from nonsmokers. When smoking was less frequent in the other three sample datasets, smokers and nonsmokers were at random network positions and no peer influence on smoking behavior was detected. Therefore, core/periphery network positions are still the key linking smoking prevalence and peer influence among US adolescents and young adults but operating through a different mechanism from their adult counterparts. When scientists design and conduct prevention programs against adolescent and young adult smoking behavior, core/periphery network positions, smoking prevalence, and peer influence should all be taken into consideration.

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