scholarly journals Adipokines and Sexual Hormones Associated with the Components of the Metabolic Syndrome in Pharmacologically Untreated Subjects: Data from the Brisighella Heart Study

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Arrigo F. G. Cicero ◽  
Paolo Magni ◽  
Massimo Moré ◽  
Massimiliano Ruscica ◽  
Elena Dozio ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Protective Factor ◽  
Plasma Lipids ◽  
Sexual Hormones ◽  
Men And Women ◽  
The Metabolic Syndrome ◽  
Heart Study ◽  
Main Factor

We evaluated the association of the sex hormone pattern and the serum level of the main adipokines to metabolic syndrome (MS) and its components in 199 pharmacologically untreated subjects. Men and women included in the age-class subgroups were matched for body mass index, waist circumference, blood pressure, heart rate, fasting plasma glucose, and plasma lipids. Men without MS had significantly lower leptin/adiponectin ratio than men with MS. Women without MS had lower leptin and leptin/adiponectin ratio than women with MS but had significantly higher adiponectin, estrone, and dehydroepiandrosterone levels. In men, the leptin/adiponectin ratio is the main factor associated to MS diagnosis (OR: 3.36, 95% CI 1.40–8.08), while in women adiponectin alone appears to be a protective factor (OR: 0.87, 95% CI 0.79–0.95). In conclusion, in a sample of pharmacologically untreated subjects, leptin/adiponectin ratio seems to be the factor more strongly associated to MS and its components.

Abstract P084: Associations of Anger and Hostility with the Metabolic Syndrome: Cross-sectional Analyses from the Jackson Heart Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Janice E Williams ◽  
Sharon B Wyatt ◽  
Mario Sims ◽  
Thomas H Mosley ◽  
Patricia M Dubbert ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
African American ◽  
Disease Risk ◽  
African American Men ◽  
Cardiovascular Disease Risk ◽  
Continuous Variables ◽  
Jackson Heart Study ◽  
Men And Women ◽  
The Metabolic Syndrome ◽  
Heart Study

There is evidence that anger and hostility are positively associated with the metabolic syndrome. In turn, the metabolic syndrome mediates the association between anger and hostility and adverse cardiac events. Very little is known about these associations in African-American populations. We assessed the hypothesis that anger and hostility are positively associated with the metabolic syndrome in an African-American cohort. Participants were 2,732 African-American men and women, ages 45 – 95, who were enrolled in the Jackson Heart Study at baseline. Anger was measured using the Spielberger State-Trait Anger Inventory, and hostility was measured using the Cook-Medley Hostility Scale. The metabolic syndrome was defined by the National Cholesterol Education Program, Adult Treatment Panel III criteria. Overall anger, components anger-in and anger-out, and hostility scores were entered into separate logistic regression models as continuous variables. In models adjusted for age, sex, educational level, and physical activity, higher levels of overall anger (β = 0.024, p = 0.006), anger-in (β = 0.028, p = 0.04), anger-out (β = 0.037, p = 0.04), and hostility (β = 0.021, p = 0.04) were associated with an increased prevalence of the metabolic syndrome. The correlation between anger and hostility was statistically significant but not strong (r = 0.38, p <0.0001). In men, 5 of the 16 individual anger items were significantly associated with the metabolic syndrome. The strongest was “I lose my temper” (β = 0.395, p = 0.003) and “I tend to harbor grudges” (β = 0.314, p = 0.008). In women, only 1 anger item, “I make sarcastic remarks” (β = 0.189, p = 0.04) was associated with the metabolic syndrome. In conclusion, higher levels of overall anger, anger-in, anger-out, and hostility were associated with an increased prevalence of the metabolic syndrome in middle- and older-aged African-American men and women. In men, an angry temperament and a tendency to hold grudges were particularly strong correlates of the metabolic syndrome. Increased understanding of the negative emotions anger and hostility among African-Americans may provide greater insights into cardiovascular disease risk in their population.

scholarly journals Fish intake, erythrocyten-3 fatty acid status and metabolic health in Danish adolescent girls and boys

2011 ◽  
Vol 107 (5) ◽  
pp. 697-704 ◽  
Author(s):  
Lotte Lauritzen ◽  
Laurine B. S. Harsløf ◽  
Lars I. Hellgren ◽  
Maiken H. Pedersen ◽  
Christian Mølgaard ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Plasma Lipids ◽  
Fish Intake ◽  
Birth Cohort Study ◽  
Food Diary ◽  
Chain Pufa ◽  
The Metabolic Syndrome ◽  
Adolescent Girls And Boys ◽  
Acid Status

Marinen-3 long-chain PUFA (n-3 LCPUFA) may have a beneficial effect on several aspects of the metabolic syndrome (dyslipidaemia, insulin resistance, hypertension and abdominal obesity). The metabolic syndrome is increasing in prevalence during adolescence, but only few studies have investigated the effects ofn-3 LCPUFA in adolescence. The present study examines associations between fish intake (assessed by a 7 d pre-coded food diary), erythrocyte (RBC) DHA status (analysed by GC) and metabolic syndrome measures (anthropometry, blood pressure and plasma lipids, insulin and glucose) in 109 17-year-old children from the Copenhagen Birth Cohort Study. Of the children, 8 % were overweight or obese and few showed signs of the metabolic syndrome, but all the metabolic syndrome variables were correlated. Median fish intake was 10·7 (interquartile range 3·6–21·2) g/d. Boys tended to have a higher fish intake (P = 0·052), but girls had significantly higher RBC levels of DHA (P = 0·001). Sex and fish intake explained 37 % of the variance in RBC-DHA (P < 0·001). After adjusting for confounders, high DHA status was found to be significantly correlated with higher systolic blood pressure (P = 0·014) and increased fasting insulin (P = 0·018), but no adverse association was observed with the mean metabolic syndromez-score. Overall, the present study showed the expected association between fish intake and RBC-DHA, which in contrast to our expectations tended to be associated with a poorer metabolic profile. Whether these results reflect the physiological function ofn-3 LCPUFA, lifestyle factors associated with fish intake in Denmark, or mere chance remains to be investigated.

scholarly journals The Increasing Prevalence of Metabolic Syndrome among Finnish Men and Women over a Decade

2008 ◽  
Vol 93 (3) ◽  
pp. 832-836 ◽  
Author(s):  
Gang Hu ◽  
Jaana Lindström ◽  
Pekka Jousilahti ◽  
Markku Peltonen ◽  
Lena Sjöberg ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Glucose Metabolism ◽  
National Cholesterol Education Program ◽  
Central Obesity ◽  
International Diabetes Federation ◽  
Population Surveys ◽  
Cross Sectional ◽  
Men And Women ◽  
The Metabolic Syndrome

Abstract Objective: Our objective was to assess a 10-yr change in the prevalence of the metabolic syndrome defined by the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) among Finnish men and women. Design and Subjects: Two cross-sectional population surveys were performed in Finland in 1992 and 2002. A total of 3495 participants aged 45–64 yr were included in the analysis. Results: In both years the metabolic syndrome was more common among men than women. In men the prevalence of the metabolic syndrome tended to increase slightly between 1992 and 2002, from 48.8–52.6% (P = 0.139) based on the NCEP definition, and from 51.4–55.6% based on the IDF definition (P = 0.102). In women the prevalence of the metabolic syndrome increased significantly from 32.2–39.1% based on the NCEP definition (P = 0.003), and from 38.0–45.3% based on the IDF definition (P = 0.002). In both sexes the prevalence of high blood pressure decreased, but the abnormalities in glucose metabolism increased between 1992 and 2002. The prevalence of central obesity increased in women between 1992 and 2002. Conclusions: In Finland the prevalence of the metabolic syndrome, based both on the NCEP and IDF definitions, is higher in men than women. However, the increase in the prevalence of the metabolic syndrome, from 1992–2002, was significant only among women.

scholarly journals Increased body mass index adversely affects dyslipidemias, blood pressure and inflammation in men and women with metabolic syndrome (LB365)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Catherine Andersen ◽  
David Aguilar ◽  
Jennifer Jones ◽  
Christopher Blesso ◽  
Taif Al‐Sarraj ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Men And Women

scholarly journals Association of total bilirubin and indirect bilirubin content with metabolic syndrome among Kazakhs in Xinjiang

2020 ◽  
Author(s):  
Hao Hao ◽  
Heng Guo ◽  
Ru-lin Ma ◽  
Yi-zhong Yan ◽  
Yun-hua Hu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Protective Factor ◽  
Total Bilirubin ◽  
Incidence Density ◽  
Cox Regression Analysis ◽  
Indirect Bilirubin ◽  
The Metabolic Syndrome ◽  
High Level

Abstract Background: Some studies have shown that a high level of bilirubin is a protective factor against the metabolic syndrome (MS), while a high level of transaminase is a risk factor for the MS. However, the results are inconsistent, and there are few cohort studies.Methods: Using an ambispective cohort study, 565 Kazakhs from Xinjiang, China were selected as the study subjects. The serum bilirubin and transaminase levels of the subjects were divided into quartiles, and their relationships with MS and its components were analyzed. The definition of metabolic syndrome was based on the Joint Interim Statement (JIS) diagnostic criteria.Results: The average follow-up time for the subjects was 5.72 years. 204 subjects had MS, the cumulative incidence was 36.11%, and the incidence density was 63.10/1000 person-years. Multivariate Cox regression analysis showed that the levels of total bilirubin (TBIL) and indirect bilirubin (IBIL) were negatively correlated with the occurrence of MS. Compared to the lowest quartile level (Q1), the hazard ratios of MS for levels of TBIL at the Q2-Q4 quartile were: 0.408 (0.266-0.626), 0.374 (0.244-0.572), and 0.328 (0.216-0.500) while IBIL at Q2-Q4 level showed an MS hazard ratio of 0.572 (0.374-0.875), 0.432 (0.283-0.659), 0.434 (0.289-0.653), all at a 95% confidence level. In addition, TBIL and IBIL levels were negatively correlated with increased blood pressure, waist circumference, and triglyceride levels, and their highest TBIL quartile risk (Q4) was 0.479, 0.484, and 0.498 times higher than the lowest quartile (Q1).Conclusion: Serum TBIL and IBIL levels were negatively correlated with MS and its components (blood pressure, waist circumference and triglycerides).

scholarly journals Association of total bilirubin and indirect bilirubin content with metabolic syndrome among Kazakhs in Xinjiang

2020 ◽  
Author(s):  
Hao Hao ◽  
Heng Guo ◽  
Ru-lin Ma ◽  
Yi-zhong Yan ◽  
Yun-hua Hu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Protective Factor ◽  
Total Bilirubin ◽  
Incidence Density ◽  
Cox Regression Analysis ◽  
Indirect Bilirubin ◽  
The Metabolic Syndrome ◽  
High Level

Abstract Background Some studies have shown that a high level of bilirubin is a protective factor against the metabolic syndrome (MS), while a high level of transaminase is a risk factor for the MS. However, the results are inconsistent, and there are few cohort studies.Methods Using an ambispective cohort study, 565 Kazakhs from Xinjiang, China were selected as the study subjects. The serum bilirubin and transaminase levels of the subjects were divided into quartiles, and their relationships with MS and its components were analyzed. The definition of metabolic syndrome was based on the Joint Interim Statement (JIS) diagnostic criteria.Results The average follow-up time for the subjects was 5.72 years. 204 subjects had MS, the cumulative incidence was 36.11%, and the incidence density was 63.10/1000 person-years. Multivariate Cox regression analysis showed that the levels of total bilirubin (TBIL) and indirect bilirubin (IBIL) were negatively correlated with the occurrence of MS. Compared to the lowest quartile level (Q1), the hazard ratios of MS for levels of TBIL at the Q2-Q4 quartile were: 0.408 (0.266-0.626), 0.374 (0.244-0.572), and 0.328 (0.216-0.500) while IBIL at Q2-Q4 level showed an MS hazard ratio of 0.572 (0.374-0.875), 0.432 (0.283-0.659), 0.434 (0.289-0.653), all at a 95% confidence level. In addition, TBIL and IBIL levels were negatively correlated with increased blood pressure, waist circumference, and triglyceride levels, and their highest TBIL quartile risk (Q4) was 0.479, 0.484, and 0.498 times higher than the lowest quartile (Q1).Conclusion Serum TBIL and IBIL levels were negatively correlated with MS and its components (blood pressure, waist circumference and triglycerides).

scholarly journals Impact of parental smoking on diabetes, hypertension and the metabolic syndrome in adult men and women in the San Antonio Heart Study

Diabetologia ◽  
2006 ◽  
Vol 49 (10) ◽  
pp. 2291-2298 ◽  
Author(s):  
K. J. Hunt ◽  
A. Hansis-Diarte ◽  
K. Shipman ◽  
J. E. Korte ◽  
S. P. Fowler ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
San Antonio ◽  
Parental Smoking ◽  
Men And Women ◽  
Adult Men ◽  
The Metabolic Syndrome ◽  
Heart Study

scholarly journals Age- and Gender-Specific Components of the Metabolic Syndrome in 2228 First Graders: The PEP Family Heart Study

Scientifica ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Peter Schwandt ◽  
Thomas Bertsch ◽  
Evelyn Liepold ◽  
Gerda-Maria Haas
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
First Graders ◽  
Growth Curves ◽  
Age And Gender ◽  
The Metabolic Syndrome ◽  
Family Heart Study ◽  
Heart Study ◽  
And Gender ◽  
Gender Specific

Because first graders are critical for excess weight gain, we assessed components of the metabolic syndrome (MetS) using the pediatric definition of the International Diabetes Federation (IDF). We compared four MetS components as defined by the IDF with age- and gender-specific components in 2228 first graders at the age of 6. The growth curves were derived from 22113 children and adolescents who participated in the PEP Family Heart Study. The aim was to determine in first graders precise values of waist circumference (WC), blood pressure (BP), triglycerides (TG), and HDL-Cholesterol (HDL-C) based on growth curves that were developed for a large German population of youths and to assess the prevalence in terms of both definitions at this critical age. The prevalence of high blood pressure for age was 13% compared with only 2% according to IDF. Because of this considerable divergence, we propose to define MetS components based on national growth curves.

Sign in / Sign up

Export Citation Format

Share Document