scholarly journals Automated Analysis of Crackles in Patients with Interstitial Pulmonary Fibrosis

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
B. Flietstra ◽  
N. Markuzon ◽  
A. Vyshedskiy ◽  
R. Murphy
Keyword(s):  
Heart Failure ◽  
Pulmonary Fibrosis ◽  
Automated Analysis ◽  
Support Vector ◽  
Inappropriate Therapy ◽  
Lung Sound ◽  
Distinctive Features ◽  
Interstitial Pulmonary Fibrosis ◽  
Machine Learning Methods ◽  
Vector Machines

Background. The crackles in patients with interstitial pulmonary fibrosis (IPF) can be difficult to distinguish from those heard in patients with congestive heart failure (CHF) and pneumonia (PN). Misinterpretation of these crackles can lead to inappropriate therapy. The purpose of this study was to determine whether the crackles in patients with IPF differ from those in patients with CHF and PN.Methods. We studied 39 patients with IPF, 95 with CHF and 123 with PN using a 16-channel lung sound analyzer. Crackle features were analyzed using machine learning methods including neural networks and support vector machines.Results. The IPF crackles had distinctive features that allowed them to be separated from those in patients with PN with a sensitivity of 0.82, a specificity of 0.88 and an accuracy of 0.86. They were separated from those of CHF patients with a sensitivity of 0.77, a specificity of 0.85 and an accuracy of 0.82.Conclusion. Distinctive features are present in the crackles of IPF that help separate them from the crackles of CHF and PN. Computer analysis of crackles at the bedside has the potential of aiding clinicians in diagnosing IPF more easily and thus helping to avoid medication errors.

Identifying Cancer Targets Based on Machine Learning Methods via Chou’s 5-steps Rule and General Pseudo Components

2019 ◽  
Vol 19 (25) ◽  
pp. 2301-2317 ◽  
Author(s):  
Ruirui Liang ◽  
Jiayang Xie ◽  
Chi Zhang ◽  
Mengying Zhang ◽  
Hai Huang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Growth Rate ◽  
Big Data ◽  
Human Genome Project ◽  
Genome Project ◽  
Support Vector ◽  
Successful Implementation ◽  
Learning Methods ◽  
Machine Learning Methods ◽  
Vector Machines

In recent years, the successful implementation of human genome project has made people realize that genetic, environmental and lifestyle factors should be combined together to study cancer due to the complexity and various forms of the disease. The increasing availability and growth rate of ‘big data’ derived from various omics, opens a new window for study and therapy of cancer. In this paper, we will introduce the application of machine learning methods in handling cancer big data including the use of artificial neural networks, support vector machines, ensemble learning and naïve Bayes classifiers.

scholarly journals Predictive modeling for peri-implantitis by using machine learning techniques

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tomoaki Mameno ◽  
Masahiro Wada ◽  
Kazunori Nozaki ◽  
Toshihito Takahashi ◽  
Yoshitaka Tsujioka ◽  
...  
Keyword(s):  
Machine Learning ◽  
Demographic Data ◽  
Risk Indicators ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Machine Learning Methods ◽  
Complex Interactions ◽  
Learning Techniques ◽  
Increased Risk ◽  
Vector Machines

AbstractThe purpose of this retrospective cohort study was to create a model for predicting the onset of peri-implantitis by using machine learning methods and to clarify interactions between risk indicators. This study evaluated 254 implants, 127 with and 127 without peri-implantitis, from among 1408 implants with at least 4 years in function. Demographic data and parameters known to be risk factors for the development of peri-implantitis were analyzed with three models: logistic regression, support vector machines, and random forests (RF). As the results, RF had the highest performance in predicting the onset of peri-implantitis (AUC: 0.71, accuracy: 0.70, precision: 0.72, recall: 0.66, and f1-score: 0.69). The factor that had the most influence on prediction was implant functional time, followed by oral hygiene. In addition, PCR of more than 50% to 60%, smoking more than 3 cigarettes/day, KMW less than 2 mm, and the presence of less than two occlusal supports tended to be associated with an increased risk of peri-implantitis. Moreover, these risk indicators were not independent and had complex effects on each other. The results of this study suggest that peri-implantitis onset was predicted in 70% of cases, by RF which allows consideration of nonlinear relational data with complex interactions.

The impact of different parameter sets on the classification of asteroid types

2021 ◽  
Author(s):  
Hanna Klimczak ◽  
Wojciech Kotłowski ◽  
Dagmara Oszkiewicz ◽  
Francesca DeMeo ◽  
Agnieszka Kryszczyńska ◽  
...  
Keyword(s):  
Gradient Boosting ◽  
Support Vector ◽  
Multilayer Perceptrons ◽  
Machine Learning Methods ◽  
Vector Machines ◽  
Science Centre ◽  
The Difference ◽  
The Impact

<p>The aim of the project is the classification of asteroids according to the most commonly used asteroid taxonomy (Bus-Demeo et al. 2009) with the use of various machine learning methods like Logistic Regression, Naive Bayes, Support Vector Machines, Gradient Boosting and Multilayer Perceptrons. Different parameter sets are used for classification in order to compare the quality of prediction with limited amount of data, namely the difference in performance between using the 0.45mu to 2.45mu spectral range and multiple spectral features, as well as performing the Prinicpal Component Analysis to reduce the dimensions of the spectral data.</p> <p> </p> <p>This work has been supported by grant No. 2017/25/B/ST9/00740 from the National Science Centre, Poland.</p>

New Approaches to the Automated Analysis of Ultrasonic In-Line Inspection Data

2004 ◽  
Author(s):  
H. Willems ◽  
K. Reber ◽  
M. Zo¨llner ◽  
M. Ziegenmeyer
Keyword(s):  
Neural Networks ◽  
Automated Analysis ◽  
Support Vector ◽  
Metal Loss ◽  
The Past ◽  
Analysis Process ◽  
Vector Machines ◽  
Speed Up ◽  
Size Limits ◽  
Inspection Data

Inline inspection of pipelines by means of intelligent pigs usually results in large amounts of data that are analyzed offline by human experts. In order to increase the reliability of the data analysis process as well as to speed up analysis times methods of artificial intelligence such as neural networks have been used in the past with more or less success. The basic requirement for any technique to be used in practice is that no relevant features should be overlooked while keeping the false call rate as low as possible. For the task of automated analysis of in-line inspection data obtained from ultrasonic metal loss inspections, we have developed a two-stage approach. In a first step (called boxing), any defect candidates exceeding the specified size limits are recognized and described by a surrounding box. In the second step, all boxes from step 1 are analyzed yielding basically a relevant/non relevant decision. Each feature considered to be relevant is then classified according to a given set of feature classes. In order to efficiently perform step 2, we have adapted the SVM (support vector machines) algorithm which offers some important advantages compared to, for example, neural networks. We describe the approach applied, and examples as obtained from in-line inspection data are presented.

scholarly journals Predicting Protein Producibility in Filamentous Fungi

2017 ◽  
Author(s):  
Karmen L Dykstra ◽  
Juho Rousu ◽  
Mikko Arvas
Keyword(s):  
Filamentous Fungi ◽  
Predictive Performance ◽  
Support Vector ◽  
E Coli ◽  
Machine Learning Methods ◽  
Vector Machines ◽  
Production Host ◽  
Domain Information ◽  
Protein Dataset ◽  
Variable Performance

AbstractIn this paper we study the problem of predicting the producibility of recombinant proteins in filamentous fungi, especially T. reesei, using machine learning methods. We train supervised and semi-supervised support vector machines with protein sequences, represented by their amino acid composition as well as protein family and domain information. Our results indicate, somewhat surprisingly, that quite modest amount of proteins with experimental data are required to build a state-of-the-art classifier and that additional unlabeled sequences in semi-supervised models do not bring increased predictive performance. Our experiments in cross-species prediction show that models trained for the filamentous fungus A. niger protein dataset can be generalized to predict protein producibility in T. reesei, and vice versa, without sacrificing too much accuracy, regardless of their approximately 500 millions years of divergence. However, predictors trained on E. coli and S. cerevisiae datasets gave variable performance when applied to the filamentous fungi datasets, indicating that while protein producibility prediction can be generalized accross related species, fully generic prediction tools applicable to any protein production host may not be realistic to achieve.

scholarly journals Rescale-Invariant SVM for Binary Classification

2017 ◽  
Author(s):  
Mojtaba Montazery ◽  
Nic Wilson
Keyword(s):  
Machine Learning ◽  
Decision Making ◽  
Support Vector Machines ◽  
Binary Classification ◽  
Experimental Results ◽  
Support Vector ◽  
Computation Method ◽  
Learning Methods ◽  
Machine Learning Methods ◽  
Vector Machines

Support Vector Machines (SVM) are among the most well-known machine learning methods, with broad use in different scientific areas. However, one necessary pre-processing phase for SVM is normalization (scaling) of features, since SVM is not invariant to the scales of the features’ spaces, i.e., different ways of scaling may lead to different results. We define a more robust decision-making approach for binary classification, in which one sample strongly belongs to a class if it belongs to that class for all possible rescalings of features. We derive a way of characterising the approach for binary SVM that allows determining when an instance strongly belongs to a class and when the classification is invariant to rescaling. The characterisation leads to a computation method to determine whether one sample is strongly positive, strongly negative or neither. Our experimental results back up the intuition that being strongly positive suggests stronger confidence that an instance really is positive.

scholarly journals An Optimized Stacked Support Vector Machines Based Expert System for the Effective Prediction of Heart Failure

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 54007-54014 ◽  
Author(s):  
Liaqat Ali ◽  
Awais Niamat ◽  
Javed Ali Khan ◽  
Noorbakhsh Amiri Golilarz ◽  
Xiong Xingzhong ◽  
...  
Keyword(s):  
Heart Failure ◽  
Support Vector Machines ◽  
Expert System ◽  
Support Vector ◽  
Vector Machines
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