scholarly journals Optoelectrofluidic Manipulation of Nanoparticles and Biomolecules

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Hyundoo Hwang ◽  
Je-Kyun Park
Keyword(s):  
Recent Progress ◽  
Clinical Diagnostics ◽  
Molecular Physics ◽  
Future Directions ◽  
Potential Applications ◽  
Optically Induced

This paper presents optoelectrofluidic technologies for manipulation of nanoparticles and biomolecules. Optoelectrofluidics provides an elegant scheme for the programmable manipulation of particles or fluids in microenvironments based on optically induced electrokinetics. Recent progress on the optoelectrofluidic manipulation of nanoobjects, which include nanospheres, nanowires, nanotubes, and biomolecules, is introduced. Some potential applications of the optoelectrofluidic nanoparticle manipulation, such as nanoparticles separation, nanostructures manufacturing, molecular physics, and clinical diagnostics, and their future directions are also discussed.

scholarly journals Signal Transduction in Leaf Senescence: Progress and Perspective

Plants ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 405 ◽  
Author(s):  
Salman Ahmad ◽  
Yongfeng Guo
Keyword(s):  
Signal Transduction ◽  
Leaf Senescence ◽  
Recent Progress ◽  
Crop Improvement ◽  
Cellular Level ◽  
Future Directions ◽  
Nutrient Remobilization ◽  
Potential Applications ◽  
Leaf Tissues ◽  
Inducing Factors

Leaf senescence is a degenerative process that is genetically controlled and involves nutrient remobilization prior to the death of leaf tissues. Age is a key developmental determinant of the process along with other senescence inducing factors. At the cellular level, different hormones, signaling molecules, and transcription factors contribute to the regulation of senescence. This review summarizes the recent progress in understanding the complexity of the senescence process with primary focuses on perception and transduction of senescence signals as well as downstream regulatory events. Future directions in this field and potential applications of related techniques in crop improvement will be discussed.

scholarly journals Perspective: Ferromagnetic Liquids

Materials ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 2712 ◽  
Author(s):  
Robert Streubel ◽  
Xubo Liu ◽  
Xuefei Wu ◽  
Thomas P. Russell
Keyword(s):  
Surface Tension ◽  
Magnetic Properties ◽  
Magnetic Nanoparticles ◽  
Remanent Magnetization ◽  
Recent Progress ◽  
Liquid Interfaces ◽  
Spin Frustration ◽  
Future Directions ◽  
Potential Applications

Mechanical jamming of nanoparticles at liquid–liquid interfaces has evolved into a versatile approach to structure liquids with solid-state properties. Ferromagnetic liquids obtain their physical and magnetic properties, including a remanent magnetization that distinguishes them from ferrofluids, from the jamming of magnetic nanoparticles assembled at the interface between two distinct liquids to minimize surface tension. This perspective provides an overview of recent progress and discusses future directions, challenges and potential applications of jamming magnetic nanoparticles with regard to 3D nano-magnetism. We address the formation and characterization of curved magnetic geometries, and spin frustration between dipole-coupled nanostructures, and advance our understanding of particle jamming at liquid–liquid interfaces.

Dual‐hormone artificial pancreas for management of type 1 diabetes: Recent progress and future directions

2021 ◽  
Author(s):  
Marco Infante ◽  
David A. Baidal ◽  
Michael R. Rickels ◽  
Andrea Fabbri ◽  
Jay S. Skyler ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Recent Progress ◽  
Artificial Pancreas ◽  
Future Directions

scholarly journals Extending McKinsey’s 7S model to understand strategic alignment in academic libraries

2019 ◽  
Vol 40 (5) ◽  
pp. 313-326 ◽  
Author(s):  
Andrew Martin Cox ◽  
Stephen Pinfield ◽  
Sophie Rutter
Keyword(s):  
Academic Libraries ◽  
Academic Library ◽  
Theoretical Work ◽  
Perceived Barriers ◽  
Future Directions ◽  
Content Type ◽  
Institutional Influences ◽  
Potential Applications ◽  
Strategic Position ◽  
Practical Implications

Purpose The purpose of this paper is to conceptualise the issues of alignment for changing academic libraries by using and extending McKinsey’s 7S model. Design/methodology/approach Theoretical work was conducted to consider and extend the 7S model for the situation of academic libraries. Empirical data were then used to confirm the value of these extensions and suggest further changes. The data to support the analysis were drawn from 33 interviews with librarians, library and non-library academics and experts, and a survey of UK library staff. Findings In the academic library context, the 7S model can be usefully extended to include three library functions (stuff, space and services) and users. It can also include institutional influences and stakeholders, and aspects of the external environment or situation, including suppliers and allies. The revised model then provides a useful framework within which data about library change can be analysed. Perceived barriers to successful performance fit the model and enable the identification of seven challenges of alignment. Research limitations/implications The resulting model has potential applications such as in the structuring analysis of academic library performance, mapping future directions of development and for exploring variations across the sector and internationally. Practical implications The revised model can be used by practitioners to think through their own strategic position and to act to shape their future, in the light of seven major areas of alignment. Originality/value The paper extends a well-known model used in strategy, to produce a more comprehensive, sector-specific analytic tool.

scholarly journals Recent progress in orexin/hypocretin physiology and pharmacology

2012 ◽  
Vol 3 (5) ◽  
pp. 447-463 ◽  
Author(s):  
Jyrki P. Kukkonen
Keyword(s):  
Stress Response ◽  
Recent Progress ◽  
Central Position ◽  
Future Directions

AbstractOrexin peptides and their cognate receptors were discovered 14 years ago. They soon took a very central position in the regulation of sleep and wakefulness. Active studies have further elucidated these functions as well as the role of orexins in, for instance, appetite, metabolism, analgesia, addiction, and stress response. This review summarizes all the important fields but especially aims at focusing on novel findings and future directions.

scholarly journals Bioengineering Approaches to Accelerate Clinical Translation of Stem Cell Therapies Treating Osteochondral Diseases

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Meng Wang ◽  
Yixuan Luo ◽  
Yin Yu ◽  
Fei Chen
Keyword(s):  
Mechanical Properties ◽  
Stem Cell ◽  
Recent Progress ◽  
Osteochondral Defect ◽  
Cell Phenotype ◽  
Stem Cell Therapies ◽  
Future Directions ◽  
Cell Therapies ◽  
Osteochondral Repair ◽  
Therapeutic Properties

The osteochondral tissue is an interface between articular cartilage and bone. The diverse composition, mechanical properties, and cell phenotype in these two tissues pose a big challenge for the reconstruction of the defected interface. Due to the availability and inherent regenerative therapeutic properties, stem cells provide tremendous promise to repair osteochondral defect. This review is aimed at highlighting recent progress in utilizing bioengineering approaches to improve stem cell therapies for osteochondral diseases, which include microgel encapsulation, adhesive bioinks, and bioprinting to control the administration and distribution. We will also explore utilizing synthetic biology tools to control the differentiation fate and deliver therapeutic biomolecules to modulate the immune response. Finally, future directions and opportunities in the development of more potent and predictable stem cell therapies for osteochondral repair are discussed.

scholarly journals Insulin - producing cells derived from stem cells: recent progress and future directions

2006 ◽  
Vol 10 (4) ◽  
pp. 866-883 ◽  
Author(s):  
A. Santana ◽  
R. Enseñat - Waser ◽  
María Isabel Arribas ◽  
J. A. Reig ◽  
E. Roche
Keyword(s):  
Stem Cells ◽  
Recent Progress ◽  
Future Directions ◽  
Insulin Producing Cells

scholarly journals Hormones and MS: Risk factors, biomarkers, and therapeutic targets

2018 ◽  
Vol 24 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Riley Bove ◽  
Wendy Gilmore
Keyword(s):  
Risk Factors ◽  
Sex Chromosomes ◽  
Recent Progress ◽  
Disease Risk ◽  
Life Stage ◽  
Therapeutic Targets ◽  
Prenatal Development ◽  
Childhood And Adolescence ◽  
Epigenetic Factors ◽  
Potential Applications

Sex differences in epidemiological, clinical, and pathological features of multiple sclerosis (MS) have been observed for decades, establishing a foundation for more recent progress in our understanding of their overall impact on the disease. In the ACTRIMS session on Hormones, Sex Chromosomes, and MS: Risk Factors, Biomarkers, and Therapeutic Targets, this progress was summarized in three presentations by pioneers in the field, revealing evidence that sex chromosomes, epigenetic factors, and sex hormones function as interactive determinants of disease risk and phenotype in a fashion dependent upon life stage, from prenatal development, childhood, and adolescence to adulthood and aging. Implications for the effects of puberty, pregnancy, menopause, and andropause on autoimmune and neurodegenerative mechanisms were discussed, along with potential applications of exogenous hormones. Although several limitations in current approaches and concepts were noted, current insights pave the way for future progress in our understanding of this enigmatic disease

Recent Progress in Chemical Modification of the Natural Polysaccharide Guar Gum

2021 ◽  
Vol 18 ◽  
Author(s):  
Simran Kaur ◽  
Soumava Santra
Keyword(s):  
Chemical Modification ◽  
Recent Progress ◽  
Guar Gum ◽  
Biological Properties ◽  
Hydroxyl Groups ◽  
Chemical Modifications ◽  
Natural Polysaccharide ◽  
Potential Applications ◽  
Pharmaceutical Industries

: Guar gum (GG) is a natural heteropolysaccharide. Due to its non-toxic, eco-friendly, and biodegradable nature, GG has found wide applications in many areas, in particular food, paper, textile, petroleum, and pharmaceutical industries. Therefore, GG is often called “Black Gold” as well. Due to the presence of hydroxyl groups, GG can be modified by various methods. The physical and biological properties of GG can be modulated by chemical modifications. In this manuscript, various methods for the chemical modifications of GG have been discussed according to the type of modifications. Mechanistic insights have also been provided whenever possible. In addition, potential applications of new GG derivatives have also been briefly mentioned.

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